메뉴 건너뛰기




Volumn 41, Issue 4, 2014, Pages 525-533

Altered serum levels of adipokines and insulin in Probable Alzheimer's disease

Author keywords

Adiponectin; Alzheimer's disease; Amyloid ; Insulin; Leptin

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; CHOLESTEROL; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LEPTIN; TRIACYLGLYCEROL;

EID: 84922677289     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-140006     Document Type: Article
Times cited : (92)

References (61)
  • 1
    • 84857036121 scopus 로고    scopus 로고
    • Epidemiology of dementia
    • McNamara P, ed. ABC-CLIO, California
    • Qiu C, Fratiglioni L (2011) Epidemiology of dementia. In Dementia Treatments and Developments, McNamara P, ed. ABC-CLIO, California, pp. 1-33.
    • (2011) Dementia Treatments and Developments , pp. 1-33
    • Qiu, C.1    Fratiglioni, L.2
  • 2
  • 3
    • 77951060145 scopus 로고    scopus 로고
    • Proteases and proteolysis in Alzheimer disease: A multifactorial view on the disease process
    • Strooper BD (2010) Proteases and proteolysis in Alzheimer disease: A multifactorial view on the disease process. Physiol Rev 90, 465-494.
    • (2010) Physiol Rev , vol.90 , pp. 465-494
    • Strooper, B.D.1
  • 4
    • 84882939776 scopus 로고    scopus 로고
    • Advances in the patho-genesis of Alzheimer's disease: A re-evaluation of amyloid cascade hypothesis
    • Dong S, Duan Y, Hu Y, Zhao Z (2012) Advances in the patho-genesis of Alzheimer's disease: A re-evaluation of amyloid cascade hypothesis. Transl Neurodegener 1, 18.
    • (2012) Transl Neurodegener , vol.1 , pp. 18
    • Dong, S.1    Duan, Y.2    Hu, Y.3    Zhao, Z.4
  • 5
    • 84868127393 scopus 로고    scopus 로고
    • From mitochon-drial dysfunction to amyloid beta formation: Novel insights into the pathogenesis of Alzheimer's disease
    • Leuner K, Muller WE, Reichert AS (2012) From mitochon-drial dysfunction to amyloid beta formation: Novel insights into the pathogenesis of Alzheimer's disease. Mol Neurobiol 46, 186-193.
    • (2012) Mol Neurobiol , vol.46 , pp. 186-193
    • Leuner, K.1    Muller, W.E.2    Reichert, A.S.3
  • 6
    • 69049109744 scopus 로고    scopus 로고
    • Biomarkers ofoxidative and nitrosative damage in Alzheimer's disease and mild cognitive impairment
    • Mangialasche F, Polidori MC, Monastero R (2009) Biomarkers ofoxidative and nitrosative damage in Alzheimer's disease and mild cognitive impairment. Aging Res Rev 8, 285-305.
    • (2009) Aging Res Rev , vol.8 , pp. 285-305
    • Mangialasche, F.1    Polidori, M.C.2    Monastero, R.3
  • 7
    • 45749151056 scopus 로고    scopus 로고
    • Animal models of Alzheimer's disease and frontotemporal dementia
    • Gotz J, Ittner LM (2008) Animal models of Alzheimer's disease and frontotemporal dementia. Nat Rev Neurosci 9, 532-544.
    • (2008) Nat Rev Neurosci , vol.9 , pp. 532-544
    • Gotz, J.1    Ittner, L.M.2
  • 8
    • 84867131908 scopus 로고    scopus 로고
    • Alzheimer's disease in a dish: Promisesand challengesofhuman stemcell models
    • Young JE, Goldstein LS (2012) Alzheimer's disease in a dish: Promisesand challengesofhuman stemcell models. Hum Mol Genet 21, R82-R89.
    • (2012) Hum Mol Genet , vol.21 , pp. R82-R89
    • Young, J.E.1    Goldstein, L.S.2
  • 9
    • 84890521380 scopus 로고    scopus 로고
    • Serum homocys-teine, dehydroepiandrosterone sulphate and lipoprotein (a) in Alzheimer's disease and vascular dementia
    • Ray L, Khemka VK, Behera P, Bandyopadhyay K, Pal S, Pal K, Basu D, Chakrabarti S (2013) Serum homocys-teine, dehydroepiandrosterone sulphate and lipoprotein (a) in Alzheimer's disease and vascular dementia. Aging Dis 4, 57-64.
    • (2013) Aging Dis , vol.4 , pp. 57-64
    • Ray, L.1    Khemka, V.K.2    Behera, P.3    Bandyopadhyay, K.4    Pal, S.5    Pal, K.6    Basu, D.7    Chakrabarti, S.8
  • 10
    • 0029788383 scopus 로고    scopus 로고
    • Regional hypometabolism in Alzheimer's disease as measured by positron emission tomography after correction for effects of partial volume averaging
    • Meltzer CC, Zubieta JK, Brandt J, Tune LE, Mayberg HS, Frost JJ (1996) Regional hypometabolism in Alzheimer's disease as measured by positron emission tomography after correction for effects of partial volume averaging. Neurology 47, 454-461.
    • (1996) Neurology , vol.47 , pp. 454-461
    • Meltzer, C.C.1    Zubieta, J.K.2    Brandt, J.3    Tune, L.E.4    Mayberg, H.S.5    Frost, J.J.6
  • 11
    • 77950911528 scopus 로고    scopus 로고
    • Reduced lean mass in early Alzheimer disease and its association with brain atrophy
    • Burns JM, Johnson DK, Watts A, Swerdlow RH, Brooks WM (2010) Reduced lean mass in early Alzheimer disease and its association with brain atrophy. Arch Neurol 67, 428-433.
    • (2010) Arch Neurol , vol.67 , pp. 428-433
    • Burns, J.M.1    Johnson, D.K.2    Watts, A.3    Swerdlow, R.H.4    Brooks, W.M.5
  • 13
    • 84255175411 scopus 로고    scopus 로고
    • Obesity, leptin, and Alzheimer's disease
    • Lee EB (2011) Obesity, leptin, and Alzheimer's disease. Ann NY Acad Sci 1243, 15-29.
    • (2011) Ann NY Acad Sci , vol.1243 , pp. 15-29
    • Lee, E.B.1
  • 19
    • 0031449491 scopus 로고    scopus 로고
    • Human plasma leptin in obese subjects and diabetics
    • Tasaka Y, Yanagisawa K, Iwamoto Y (1997) Human plasma leptin in obese subjects and diabetics. Endocr J 44, 671-676.
    • (1997) Endocr J , vol.44 , pp. 671-676
    • Tasaka, Y.1    Yanagisawa, K.2    Iwamoto, Y.3
  • 20
    • 9144235551 scopus 로고    scopus 로고
    • Adiponectin and leptin in relation to insulin sensitivity
    • Soodini GR (2004) Adiponectin and leptin in relation to insulin sensitivity. Metab Syndr Relat Disord 2, 114-123.
    • (2004) Metab Syndr Relat Disord , vol.2 , pp. 114-123
    • Soodini, G.R.1
  • 24
    • 84863229451 scopus 로고    scopus 로고
    • Lipids and adipokines as risk factors for Alzheimer's disease
    • Warren MW, Hynan LS, Weiner MF (2012) Lipids and adipokines as risk factors for Alzheimer's disease. J Alzheimers Dis 29, 151-157.
    • (2012) J Alzheimers Dis , vol.29 , pp. 151-157
    • Warren, M.W.1    Hynan, L.S.2    Weiner, M.F.3
  • 26
    • 84860903756 scopus 로고    scopus 로고
    • Biomarkers for insulin resistance and inflammation and the risk for all-cause dementia and Alzheimer disease: Results from the framingham heart study
    • Van Himbergen TM, Beiser AS, Ai M, Seshadri S, Otokozawa S, Au R, Thongtang N, Wolf PA, Schaefer EJ (2012) Biomarkers for insulin resistance and inflammation and the risk for all-cause dementia and Alzheimer disease: Results from the Framingham Heart Study. Arch Neurol 69, 594-600.
    • (2012) Arch Neurol , vol.69 , pp. 594-600
    • Van Himbergen, T.M.1    Beiser, A.S.2    Ai, M.3    Seshadri, S.4    Otokozawa, S.5    Au, R.6    Thongtang, N.7    Wolf, P.A.8    Schaefer, E.J.9
  • 27
    • 84856450866 scopus 로고    scopus 로고
    • Leptin: A novel therapeutic target in Alzheimer's disease?
    • Beccano-Kelly D, Harvey J (2012) Leptin: A novel therapeutic target in Alzheimer's disease? Int J Alzheimers Dis 2012, 594137.
    • (2012) Int J Alzheimers Dis , vol.2012 , pp. 594137
    • Beccano-Kelly, D.1    Harvey, J.2
  • 29
  • 30
    • 37549040190 scopus 로고    scopus 로고
    • The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS
    • Kadowaki T, Yamauchi T, Kubota N (2008) The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS. FEBS Lett 582, 74-80.
    • (2008) FEBS Lett , vol.582 , pp. 74-80
    • Kadowaki, T.1    Yamauchi, T.2    Kubota, N.3
  • 31
    • 33745834319 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
    • Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K (2006) Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Invest 116, 1784-1792.
    • (2006) J Clin Invest , vol.116 , pp. 1784-1792
    • Kadowaki, T.1    Yamauchi, T.2    Kubota, N.3    Hara, K.4    Ueki, K.5    Tobe, K.6
  • 34
    • 67649742213 scopus 로고    scopus 로고
    • Risk of incident Alzheimer's disease in diabetic patients: A systematic review of prospective trials
    • Kopf D, Frolich L (2009) Risk of incident Alzheimer's disease in diabetic patients: A systematic review of prospective trials. J Alzheimers Dis 16, 677-685.
    • (2009) J Alzheimers Dis , vol.16 , pp. 677-685
    • Kopf, D.1    Frolich, L.2
  • 35
    • 84874455392 scopus 로고    scopus 로고
    • Type 2 diabetes as a risk factor for Alzheimer's disease: The confounders, interactions, and neuropathology associated with this relationship
    • Vagelatos NT, Eslick GD (2013) Type 2 diabetes as a risk factor for Alzheimer's disease: The confounders, interactions, and neuropathology associated with this relationship. Epidemiol Rev 35, 152-160.
    • (2013) Epidemiol Rev , vol.35 , pp. 152-160
    • Vagelatos, N.T.1    Eslick, G.D.2
  • 36
    • 79960896430 scopus 로고    scopus 로고
    • Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes
    • Liu Y, Liu F, Grundke-Iqbal I, Iqbal K, Gong CX (2011) Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes. J Pathol 225, 54-62.
    • (2011) J Pathol , vol.225 , pp. 54-62
    • Liu, Y.1    Liu, F.2    Grundke-Iqbal, I.3    Iqbal, K.4    Gong, C.X.5
  • 37
    • 79960555700 scopus 로고    scopus 로고
    • Possible implications of insulin resistance and glucose metabolism in Alzheimer's disease pathogenesis
    • Bosco D, Fava A, Plastino M, Montalcini T, Pujia A (2011) Possible implications of insulin resistance and glucose metabolism in Alzheimer's disease pathogenesis. J Cell Mol Med 15, 1807-1821.
    • (2011) J Cell Mol Med , vol.15 , pp. 1807-1821
    • Bosco, D.1    Fava, A.2    Plastino, M.3    Montalcini, T.4    Pujia, A.5
  • 38
    • 0036828769 scopus 로고    scopus 로고
    • Alzheimer's disease: Treatment in discovery and development
    • Citron M (2002) Alzheimer's disease: Treatment in discovery and development. Nat Neurosci 5, 1055-1057.
    • (2002) Nat Neurosci , vol.5 , pp. 1055-1057
    • Citron, M.1
  • 39
    • 0036227542 scopus 로고    scopus 로고
    • Type 2 diabetes, diabetes, apo E gene and the risk for dementia and related pathogenesis: The honolulu-Asia aging study
    • Peila R, Rodriguez BL, Lauren LJ (2002) Type 2 diabetes, diabetes, Apo E gene and the risk for dementia and related pathogenesis: The Honolulu-Asia Aging Study. Diabetes 51, 1256-1262.
    • (2002) Diabetes , vol.51 , pp. 1256-1262
    • Peila, R.1    Rodriguez, B.L.2    Lauren, L.J.3
  • 41
    • 84883555275 scopus 로고    scopus 로고
    • Renin-angiotensin system blockers affect cognitive decline and serum adipocytokines in Alzheimer's disease
    • Furiya Y, Ryo M, Kawahara M, Kiriyama T, Morikawa M, Ueno S (2013) Renin-angiotensin system blockers affect cognitive decline and serum adipocytokines in Alzheimer's disease. Alzheimers Dement 9, 512-518.
    • (2013) Alzheimers Dement , vol.9 , pp. 512-518
    • Furiya, Y.1    Ryo, M.2    Kawahara, M.3    Kiriyama, T.4    Morikawa, M.5    Ueno, S.6
  • 42
    • 84896472465 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus and Alzheimer's disease: From physiopathology to treatment implications
    • Moreira RO, Campos SC, Soldera AL (2013) Type 2 diabetes mellitus and Alzheimer's disease: From physiopathology to treatment implications. Diabetes Metab Res Rev, doi: 10.1002/dmrr.2442
    • (2013) Diabetes Metab Res Rev
    • Moreira, R.O.1    Campos, S.C.2    Soldera, A.L.3
  • 46
    • 0345669752 scopus 로고    scopus 로고
    • Alzheimer's disease: The cholesterol connection
    • Puglielli L, Tanzi RE, Kovacs DM (2003) Alzheimer's disease: The cholesterol connection. Nat Neurosci 6, 345-351.
    • (2003) Nat Neurosci , vol.6 , pp. 345-351
    • Puglielli, L.1    Tanzi, R.E.2    Kovacs, D.M.3
  • 47
    • 80051472136 scopus 로고    scopus 로고
    • Oxysterols as biomarkers in neurodegenerative diseases
    • Leoni V, Caccia C (2011) Oxysterols as biomarkers in neurodegenerative diseases. Chem Phys Lipids 164, 515-524.
    • (2011) Chem Phys Lipids , vol.164 , pp. 515-524
    • Leoni, V.1    Caccia, C.2
  • 49
    • 0033958076 scopus 로고    scopus 로고
    • Serum cholesterol, APOE genotype, and the risk of Alzheimer's disease: A population-based study of African Americans
    • Evans RM, Emsley CL, Gao S, Sahota A, Hall KS, Farlow MR, Hendrie H (2000) Serum cholesterol, APOE genotype, and the risk of Alzheimer's disease: A population-based study of African Americans. Neurology 54, 240-242.
    • (2000) Neurology , vol.54 , pp. 240-242
    • Evans, R.M.1    Emsley, C.L.2    Gao, S.3    Sahota, A.4    Hall, K.S.5    Farlow, M.R.6    Hendrie, H.7
  • 50
    • 2442684094 scopus 로고    scopus 로고
    • Cholesterol and APOE genotype interact to influence Alzheimer disease progression
    • Evans RM, Hui S, Perkins A, Lahiri DK, Poirier J, Farlow MR (2004) Cholesterol and APOE genotype interact to influence Alzheimer disease progression. Neurology 62, 1869-1871.
    • (2004) Neurology , vol.62 , pp. 1869-1871
    • Evans, R.M.1    Hui, S.2    Perkins, A.3    Lahiri, D.K.4    Poirier, J.5    Farlow, M.R.6
  • 51
    • 0036300343 scopus 로고    scopus 로고
    • Hypertension and hypercholesterolaemia as risk factors for Alzheimer's disease: Potential for pharmacological intervention
    • Kivipelto M, Laakso MP, Tuomilehto J, Nissinen A, Soininen H (2002) Hypertension and hypercholesterolaemia as risk factors for Alzheimer's disease: Potential for pharmacological intervention. CNS Drugs 16, 435-444.
    • (2002) CNS Drugs , vol.16 , pp. 435-444
    • Kivipelto, M.1    Laakso, M.P.2    Tuomilehto, J.3    Nissinen, A.4    Soininen, H.5
  • 53
    • 77955657566 scopus 로고    scopus 로고
    • Beyond the signaling effect role of amyloid ß42 on the processing of APP, and its clinical implications
    • Lahiri DK, Maloney B (2010) Beyond the signaling effect role of amyloid ß42 on the processing of APP, and its clinical implications. Exp Neurol 225, 51-54.
    • (2010) Exp Neurol , vol.225 , pp. 51-54
    • Lahiri, D.K.1    Maloney, B.2
  • 54
    • 3442878151 scopus 로고    scopus 로고
    • Cholesterol and Alzheimer's disease: Clinical and experimental models suggest interactions of different genetic, dietary and environmental risk factors
    • Sambamurti K, Granholm AC, Kindy MS, Bhat NR, Greig NH, Lahiri DK, Mintzer JE (2004) Cholesterol and Alzheimer's disease: Clinical and experimental models suggest interactions of different genetic, dietary and environmental risk factors. Curr Drug Targets 5, 517-528.
    • (2004) Curr Drug Targets , vol.5 , pp. 517-528
    • Sambamurti, K.1    Granholm, A.C.2    Kindy, M.S.3    Bhat, N.R.4    Greig, N.H.5    Lahiri, D.K.6    Mintzer, J.E.7
  • 55
    • 70350432817 scopus 로고    scopus 로고
    • The LEARn model: An epigenetic explanation for idiopathic neurobiological diseases
    • Lahiri DK, Maloney B, Zawia NH (2009) The LEARn model: An epigenetic explanation for idiopathic neurobiological diseases. Mol Psychiatry 14, 992-1003.
    • (2009) Mol Psychiatry , vol.14 , pp. 992-1003
    • Lahiri, D.K.1    Maloney, B.2    Zawia, N.H.3
  • 57
    • 80053928598 scopus 로고    scopus 로고
    • Cholesterol level and statin usein Alzheimer disease: I. Review of epidemi-ological and preclinical studies
    • Shepardson NE, Shankar GM, Selkoe DJ (2011) Cholesterol level and statin usein Alzheimer disease: I. Review of epidemi-ological and preclinical studies. Arch Neurol 68, 1239-1244.
    • (2011) Arch Neurol , vol.68 , pp. 1239-1244
    • Shepardson, N.E.1    Shankar, G.M.2    Selkoe, D.J.3
  • 58
    • 81355164295 scopus 로고    scopus 로고
    • Cholesterol level and statin use in Alzheimer disease: II. Review of human trials and recommendations
    • Shepardson NE, Shankar GM, Selkoe DJ (2011) Cholesterol level and statin use in Alzheimer disease: II. Review of human trials and recommendations. Arch Neurol 68, 1385-1392.
    • (2011) Arch Neurol , vol.68 , pp. 1385-1392
    • Shepardson, N.E.1    Shankar, G.M.2    Selkoe, D.J.3
  • 59
    • 79956076567 scopus 로고    scopus 로고
    • Introduction to the recommendations from the national institute on aging-Alzheimer's association workgroups on diagnostic guidelines for Alzheimer's disease
    • Jack CR Jr, Albert MS, Knopman DS, McKhann GM, Sperling RA, Carrillo MC, Thies B, Phelps CH (2011) Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7, 257-262.
    • (2011) Alzheimers Dement , vol.7 , pp. 257-262
    • Jack, C.R.1    Albert, M.S.2    Knopman, D.S.3    McKhann, G.M.4    Sperling, R.A.5    Carrillo, M.C.6    Thies, B.7    Phelps, C.H.8
  • 61
    • 33645883249 scopus 로고    scopus 로고
    • Insulin and lep-tin induce glut4 plasma membrane translocation and glucose uptake in a human neuronal cell line by a phosphatidyli-nositol 3-kinase-dependent mechanism
    • Benomar Y, Naour N, Aubourg A, Bailleux V, Gertler A, Djiane J, Guerre-Millo M, Taouis M (2006) Insulin and lep-tin induce Glut4 plasma membrane translocation and glucose uptake in a human neuronal cell line by a phosphatidyli-nositol 3-kinase-dependent mechanism. Endocrinology 147, 2550-2556.
    • (2006) Endocrinology , vol.147 , pp. 2550-2556
    • Benomar, Y.1    Naour, N.2    Aubourg, A.3    Bailleux, V.4    Gertler, A.5    Djiane, J.6    Guerre-Millo, M.7    Taouis, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.