Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden

Brain

Volumn 134, Issue 6, 2011, Pages 1635-1646

  Drzezga, Alexander ^a,b,d   Becker, J Alex ^a   Van Dijk, Koene R A ^a,b,c   Sreenivasan, Aishwarya ^a,b   Talukdar, Tanveer ^a,b   Sullivan, Caroline ^a,b   Schultz, Aaron P ^a,b   Sepulcre, Jorge ^a,b,c   Putcha, Deepti ^a,b   Greve, Doug ^b   Johnson, Keith A ^a   Sperling, Reisa A ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD UNIVERSITY   (United States)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

amyloid; cortical hubs; functional connectivity; magnetic resonance imaging; metabolism; mild cognitive impairment; positron emission tomography

Indexed keywords

AMYLOID; FLUORODEOXYGLUCOSE F 18; GLUCOSE; N METHYL 2 (4 METHYLAMINOPHENYL) 6 HYDROXYBENZOTHIAZOLE C 11; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN ATROPHY; BRAIN DEGENERATION; BRAIN DYSFUNCTION; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; DEMENTIA; DISEASE PREDISPOSITION; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GLUCOSE METABOLISM; HUMAN; MALE; MILD COGNITIVE IMPAIRMENT; NEUROPATHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; POSTERIOR CINGULATE; PRECUNEUS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; VOXEL BASED MORPHOMETRY;

EID: 79957800704     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awr066     Document Type: Article

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