-
1
-
-
84860279257
-
The pathogenesis of early retinal changes of diabetic retinopathy
-
COI: 1:STN:280:DC%2BC38vhvFejtQ%3D%3D
-
Arden GB, Sivaprasad S (2012) The pathogenesis of early retinal changes of diabetic retinopathy. Documenta ophthalmologica Adv in ophthalmol 124:15–26
-
(2012)
Documenta ophthalmologica Adv in ophthalmol
, vol.124
, pp. 15-26
-
-
Arden, G.B.1
Sivaprasad, S.2
-
2
-
-
58049209727
-
Stabilization of HIF-1alpha is critical to improve wound healing in diabetic mice
-
PID: 19057015, COI: 1:CAS:528:DC%2BD1cXhsFamu7vK
-
Botusan IR, Sunkari VG, Savu O, Catrina AI, Grunler J, Lindberg S, Pereira T, Yla-Herttuala S, Poellinger L, Brismar K et al (2008) Stabilization of HIF-1alpha is critical to improve wound healing in diabetic mice. Proc Natl Acad Sci U S A 105:19426–19431
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 19426-19431
-
-
Botusan, I.R.1
Sunkari, V.G.2
Savu, O.3
Catrina, A.I.4
Grunler, J.5
Lindberg, S.6
Pereira, T.7
Yla-Herttuala, S.8
Poellinger, L.9
Brismar, K.10
-
3
-
-
61849161619
-
Reduced oxygenation in diabetic rat kidneys measured by T2* weighted magnetic resonance micro-imaging
-
PID: 19227472
-
Edlund J, Hansell P, Fasching A, Liss P, Weis J, Glickson JD, Palm F (2009) Reduced oxygenation in diabetic rat kidneys measured by T2* weighted magnetic resonance micro-imaging. Adv Exp Med Biol 645:199–204
-
(2009)
Adv Exp Med Biol
, vol.645
, pp. 199-204
-
-
Edlund, J.1
Hansell, P.2
Fasching, A.3
Liss, P.4
Weis, J.5
Glickson, J.D.6
Palm, F.7
-
4
-
-
53649085571
-
Ozagrel reverses streptozotocin-induced constriction of arterioles in rat retina
-
PID: 18718478, COI: 1:CAS:528:DC%2BD1cXht1Kgsr3P
-
Lee S, Morgan GA, Harris NR (2008) Ozagrel reverses streptozotocin-induced constriction of arterioles in rat retina. Microvasc Res 76:217–223
-
(2008)
Microvasc Res
, vol.76
, pp. 217-223
-
-
Lee, S.1
Morgan, G.A.2
Harris, N.R.3
-
5
-
-
44949232374
-
Neurovascular control and neurogenic inflammation in diabetes
-
PID: 18442183
-
Schaper NC, Huijberts M, Pickwell K (2008) Neurovascular control and neurogenic inflammation in diabetes. Diabetes Metab Res Rev 24(Suppl 1):S40–44
-
(2008)
Diabetes Metab Res Rev
, vol.24
, pp. S40-S44
-
-
Schaper, N.C.1
Huijberts, M.2
Pickwell, K.3
-
6
-
-
76149143129
-
Diabetic angiopathy, the complement system and the tumor necrosis factor superfamily
-
PID: 20098449, COI: 1:CAS:528:DC%2BC3cXpslCqsw%3D%3D
-
Flyvbjerg A (2010) Diabetic angiopathy, the complement system and the tumor necrosis factor superfamily. Nat Rev Endocrinol 6:94–101
-
(2010)
Nat Rev Endocrinol
, vol.6
, pp. 94-101
-
-
Flyvbjerg, A.1
-
7
-
-
46349110918
-
Diabetes-induced up-regulation of uncoupling protein-2 results in increased mitochondrial uncoupling in kidney proximal tubular cells
-
PID: 18439413, COI: 1:CAS:528:DC%2BD1cXnsFCmu7c%3D
-
Friederich M, Fasching A, Hansell P, Nordquist L, Palm F (2008) Diabetes-induced up-regulation of uncoupling protein-2 results in increased mitochondrial uncoupling in kidney proximal tubular cells. Biochim Biophys Acta 1777:935–940
-
(2008)
Biochim Biophys Acta
, vol.1777
, pp. 935-940
-
-
Friederich, M.1
Fasching, A.2
Hansell, P.3
Nordquist, L.4
Palm, F.5
-
8
-
-
77954345078
-
Oxygen homeostasis
-
PID: 20836033, COI: 1:CAS:528:DC%2BC3cXmtVSrtr4%3D
-
Semenza GL (2010) Oxygen homeostasis. Wiley Interdiscip Rev Syst Biol Med 2:336–361
-
(2010)
Wiley Interdiscip Rev Syst Biol Med
, vol.2
, pp. 336-361
-
-
Semenza, G.L.1
-
9
-
-
0031000736
-
A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development
-
PID: 9113979, COI: 1:CAS:528:DyaK2sXjtVyitbY%3D
-
Ema M, Taya S, Yokotani N, Sogawa K, Matsuda Y, Fujii-Kuriyama Y (1997) A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development. Proc Natl Acad Sci USA 94:4273–4278
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4273-4278
-
-
Ema, M.1
Taya, S.2
Yokotani, N.3
Sogawa, K.4
Matsuda, Y.5
Fujii-Kuriyama, Y.6
-
10
-
-
84655161946
-
HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression
-
COI: 1:CAS:528:DC%2BC3MXhs1aisbzM
-
Keith B, Johnson RS, Simon MC (2012) HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression. Nat Rev Cancer 12:9–22
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 9-22
-
-
Keith, B.1
Johnson, R.S.2
Simon, M.C.3
-
11
-
-
80555135912
-
Oxygen-dependent cleavage of the p75 neurotrophin receptor triggers stabilization of HIF-1alpha
-
PID: 22055192
-
Le Moan N, Houslay DM, Christian F, Houslay MD, Akassoglou K (2011) Oxygen-dependent cleavage of the p75 neurotrophin receptor triggers stabilization of HIF-1alpha. Mol Cell 44:476–490
-
(2011)
Mol Cell
, vol.44
, pp. 476-490
-
-
Le Moan, N.1
Houslay, D.M.2
Christian, F.3
Houslay, M.D.4
Akassoglou, K.5
-
12
-
-
66749129781
-
Regulation of hypoxia-inducible factor 2alpha signaling by the stress-responsive deacetylase sirtuin 1
-
PID: 19498162, COI: 1:CAS:528:DC%2BD1MXms12gurk%3D
-
Dioum EM, Chen R, Alexander MS, Zhang Q, Hogg RT, Gerard RD, Garcia JA (2009) Regulation of hypoxia-inducible factor 2alpha signaling by the stress-responsive deacetylase sirtuin 1. Science 324:1289–1293
-
(2009)
Science
, vol.324
, pp. 1289-1293
-
-
Dioum, E.M.1
Chen, R.2
Alexander, M.S.3
Zhang, Q.4
Hogg, R.T.5
Gerard, R.D.6
Garcia, J.A.7
-
13
-
-
74549142287
-
The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha
-
PID: 20141841, COI: 1:CAS:528:DC%2BC3cXkvVWitLc%3D
-
Zhong L, D’Urso A, Toiber D, Sebastian C, Henry RE, Vadysirisack DD, Guimaraes A, Marinelli B, Wikstrom JD, Nir T et al (2010) The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha. Cell 140:280–293
-
(2010)
Cell
, vol.140
, pp. 280-293
-
-
Zhong, L.1
D’Urso, A.2
Toiber, D.3
Sebastian, C.4
Henry, R.E.5
Vadysirisack, D.D.6
Guimaraes, A.7
Marinelli, B.8
Wikstrom, J.D.9
Nir, T.10
-
14
-
-
79952501323
-
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1alpha destabilization
-
PID: 21397863, COI: 1:CAS:528:DC%2BC3MXjtFKis74%3D
-
Finley LW, Carracedo A, Lee J, Souza A, Egia A, Zhang J, Teruya-Feldstein J, Moreira PI, Cardoso SM, Clish CB et al (2011) SIRT3 opposes reprogramming of cancer cell metabolism through HIF1alpha destabilization. Cancer Cell 19:416–428
-
(2011)
Cancer Cell
, vol.19
, pp. 416-428
-
-
Finley, L.W.1
Carracedo, A.2
Lee, J.3
Souza, A.4
Egia, A.5
Zhang, J.6
Teruya-Feldstein, J.7
Moreira, P.I.8
Cardoso, S.M.9
Clish, C.B.10
-
15
-
-
84878542447
-
Deciphering the emerging role of SUMO conjugation in the hypoxia-signaling cascade
-
PID: 23362194
-
Nunez-O’Mara A, Berra E (2013) Deciphering the emerging role of SUMO conjugation in the hypoxia-signaling cascade. Biol Chem 394:459–469
-
(2013)
Biol Chem
, vol.394
, pp. 459-469
-
-
Nunez-O’Mara, A.1
Berra, E.2
-
16
-
-
79952137486
-
miR-210: more than a silent player in hypoxia
-
PID: 21360638, COI: 1:CAS:528:DC%2BC3MXisV2jsrc%3D
-
Devlin C, Greco S, Martelli F, Ivan M (2011) miR-210: more than a silent player in hypoxia. IUBMB Life 63:94–100
-
(2011)
IUBMB Life
, vol.63
, pp. 94-100
-
-
Devlin, C.1
Greco, S.2
Martelli, F.3
Ivan, M.4
-
17
-
-
63449103705
-
Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis
-
PID: 19255431, COI: 1:CAS:528:DC%2BD1MXjslChu7w%3D
-
Xia X, Lemieux ME, Li W, Carroll JS, Brown M, Liu XS, Kung AL (2009) Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis. Proc Natl Acad Sci U S A 106:4260–4265
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 4260-4265
-
-
Xia, X.1
Lemieux, M.E.2
Li, W.3
Carroll, J.S.4
Brown, M.5
Liu, X.S.6
Kung, A.L.7
-
18
-
-
0014014125
-
Sorbitol pathway: presence in nerve and cord with substrate accumulation in diabetes
-
PID: 5907911, COI: 1:CAS:528:DyaF28XntVarug%3D%3D
-
Gabbay KH, Merola LO, Field RA (1966) Sorbitol pathway: presence in nerve and cord with substrate accumulation in diabetes. Science 151:209–210
-
(1966)
Science
, vol.151
, pp. 209-210
-
-
Gabbay, K.H.1
Merola, L.O.2
Field, R.A.3
-
19
-
-
0026469097
-
Complications: neuropathy, pathogenetic considerations
-
PID: 1464245, COI: 1:STN:280:DyaK3s%2FpvFOktg%3D%3D
-
Greene DA, Sima AA, Stevens MJ, Feldman EL, Lattimer SA (1992) Complications: neuropathy, pathogenetic considerations. Diabetes Care 15:1902–1925
-
(1992)
Diabetes Care
, vol.15
, pp. 1902-1925
-
-
Greene, D.A.1
Sima, A.A.2
Stevens, M.J.3
Feldman, E.L.4
Lattimer, S.A.5
-
20
-
-
48449094505
-
Polyol pathway mediates iron-induced oxidative injury in ischemic-reperfused rat heart
-
PID: 18549825, COI: 1:CAS:528:DC%2BD1cXpslWku7s%3D
-
Tang WH, Wu S, Wong TM, Chung SK, Chung SS (2008) Polyol pathway mediates iron-induced oxidative injury in ischemic-reperfused rat heart. Free Radic Biol Med 45:602–610
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 602-610
-
-
Tang, W.H.1
Wu, S.2
Wong, T.M.3
Chung, S.K.4
Chung, S.S.5
-
21
-
-
0028304845
-
Nonenzymatic glycosylation in vitro and in bovine endothelial cells alters basic fibroblast growth factor activity. A model for intracellular glycosylation in diabetes
-
PID: 8040253, COI: 1:CAS:528:DyaK2cXltlWnt7g%3D
-
Giardino I, Edelstein D, Brownlee M (1994) Nonenzymatic glycosylation in vitro and in bovine endothelial cells alters basic fibroblast growth factor activity. A model for intracellular glycosylation in diabetes. J Clin Invest 94:110–117
-
(1994)
J Clin Invest
, vol.94
, pp. 110-117
-
-
Giardino, I.1
Edelstein, D.2
Brownlee, M.3
-
22
-
-
78649753203
-
The chaperone-dependent ubiquitin ligase CHIP targets HIF-1alpha for degradation in the presence of methylglyoxal
-
PID: 21124777, COI: 1:CAS:528:DC%2BC3cXhsFaqu7nP
-
Bento CF, Fernandes R, Ramalho J, Marques C, Shang F, Taylor A, Pereira P (2010) The chaperone-dependent ubiquitin ligase CHIP targets HIF-1alpha for degradation in the presence of methylglyoxal. PLoS ONE 5:e15062
-
(2010)
PLoS ONE
, vol.5
, pp. e15062
-
-
Bento, C.F.1
Fernandes, R.2
Ramalho, J.3
Marques, C.4
Shang, F.5
Taylor, A.6
Pereira, P.7
-
23
-
-
44849131121
-
Decreasing intracellular superoxide corrects defective ischemia-induced new vessel formation in diabetic mice
-
PID: 18227068, COI: 1:CAS:528:DC%2BD1cXksFagur4%3D
-
Ceradini DJ, Yao D, Grogan RH, Callaghan MJ, Edelstein D, Brownlee M, Gurtner GC (2008) Decreasing intracellular superoxide corrects defective ischemia-induced new vessel formation in diabetic mice. J Biol Chem 283:10930–10938
-
(2008)
J Biol Chem
, vol.283
, pp. 10930-10938
-
-
Ceradini, D.J.1
Yao, D.2
Grogan, R.H.3
Callaghan, M.J.4
Edelstein, D.5
Brownlee, M.6
Gurtner, G.C.7
-
24
-
-
69449108536
-
The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues
-
PID: 19666581, COI: 1:CAS:528:DC%2BD1MXhtVOitrrF
-
Thangarajah H, Yao D, Chang EI, Shi Y, Jazayeri L, Vial IN, Galiano RD, Du XL, Grogan R, Galvez MG et al (2009) The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues. Proc Natl Acad Sci U S A 106:13505–13510
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 13505-13510
-
-
Thangarajah, H.1
Yao, D.2
Chang, E.I.3
Shi, Y.4
Jazayeri, L.5
Vial, I.N.6
Galiano, R.D.7
Du, X.L.8
Grogan, R.9
Galvez, M.G.10
-
25
-
-
9444296528
-
Hyperglycemia regulates hypoxia-inducible factor-1alpha protein stability and function
-
PID: 15561954, COI: 1:CAS:528:DC%2BD2cXhtVOls7bN
-
Catrina SB, Okamoto K, Pereira T, Brismar K, Poellinger L (2004) Hyperglycemia regulates hypoxia-inducible factor-1alpha protein stability and function. Diabetes 53:3226–3232
-
(2004)
Diabetes
, vol.53
, pp. 3226-3232
-
-
Catrina, S.B.1
Okamoto, K.2
Pereira, T.3
Brismar, K.4
Poellinger, L.5
-
26
-
-
77955835661
-
Methylglyoxal-induced imbalance in the ratio VEGF/Ang-2 secreted by retinal pigment epithelial cells leads to endothelial dysfunction
-
PID: 20562294, COI: 1:CAS:528:DC%2BC3cXhtlGjt7jP
-
Bento CF, Fernandes R, Matafome P, Sena C, Seica R, Pereira P (2010) Methylglyoxal-induced imbalance in the ratio VEGF/Ang-2 secreted by retinal pigment epithelial cells leads to endothelial dysfunction. Exp Physiol 95:955–70
-
(2010)
Exp Physiol
, vol.95
, pp. 955-970
-
-
Bento, C.F.1
Fernandes, R.2
Matafome, P.3
Sena, C.4
Seica, R.5
Pereira, P.6
-
27
-
-
0035941358
-
Regulation of vascular endothelial growth factor expression by advanced glycation end products
-
PID: 11571295, COI: 1:STN:280:DC%2BD3MnmslKhuw%3D%3D
-
Treins C, Giorgetti-Peraldi S, Murdaca J, Van Obberghen E (2001) Regulation of vascular endothelial growth factor expression by advanced glycation end products. J Biol Chem 276:43836–43841
-
(2001)
J Biol Chem
, vol.276
, pp. 43836-43841
-
-
Treins, C.1
Giorgetti-Peraldi, S.2
Murdaca, J.3
Van Obberghen, E.4
-
28
-
-
37549011413
-
Hypoxia-inducible factor-1 mediates neuronal expression of the receptor for advanced glycation end products following hypoxia/ischemia
-
PID: 17942394, COI: 1:CAS:528:DC%2BD2sXhsVSgtr%2FI
-
Pichiule P, Chavez JC, Schmidt AM, Vannucci SJ (2007) Hypoxia-inducible factor-1 mediates neuronal expression of the receptor for advanced glycation end products following hypoxia/ischemia. J Biol Chem 282:36330–36340
-
(2007)
J Biol Chem
, vol.282
, pp. 36330-36340
-
-
Pichiule, P.1
Chavez, J.C.2
Schmidt, A.M.3
Vannucci, S.J.4
-
29
-
-
84887432293
-
A liver Hif-2alpha-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition
-
PID: 24037094, COI: 1:CAS:528:DC%2BC3sXhsVeqsb7F
-
Wei K, Piecewicz SM, McGinnis LM, Taniguchi CM, Wiegand SJ, Anderson K, Chan CW, Mulligan KX, Kuo D, Yuan J et al (2013) A liver Hif-2alpha-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition. Nat Med 19:1331–1337
-
(2013)
Nat Med
, vol.19
, pp. 1331-1337
-
-
Wei, K.1
Piecewicz, S.M.2
McGinnis, L.M.3
Taniguchi, C.M.4
Wiegand, S.J.5
Anderson, K.6
Chan, C.W.7
Mulligan, K.X.8
Kuo, D.9
Yuan, J.10
-
30
-
-
37249086816
-
Adaptation to hypoxia in the diabetic rat kidney
-
PID: 17914354, COI: 1:CAS:528:DC%2BD2sXhsVaqur%2FN
-
Rosenberger C, Khamaisi M, Abassi Z, Shilo V, Weksler-Zangen S, Goldfarb M, Shina A, Zibertrest F, Eckardt KU, Rosen S et al (2008) Adaptation to hypoxia in the diabetic rat kidney. Kidney Int 73:34–42
-
(2008)
Kidney Int
, vol.73
, pp. 34-42
-
-
Rosenberger, C.1
Khamaisi, M.2
Abassi, Z.3
Shilo, V.4
Weksler-Zangen, S.5
Goldfarb, M.6
Shina, A.7
Zibertrest, F.8
Eckardt, K.U.9
Rosen, S.10
-
31
-
-
77649189113
-
Hypoxia and the expression of HIF-1alpha and HIF-2alpha in the retina of streptozotocin-injected mice and rats
-
PID: 20005221, COI: 1:CAS:528:DC%2BC3cXitVaqsrs%3D
-
Wright WS, McElhatten RM, Messina JE, Harris NR (2010) Hypoxia and the expression of HIF-1alpha and HIF-2alpha in the retina of streptozotocin-injected mice and rats. Exp Eye Res 90:405–412
-
(2010)
Exp Eye Res
, vol.90
, pp. 405-412
-
-
Wright, W.S.1
McElhatten, R.M.2
Messina, J.E.3
Harris, N.R.4
-
32
-
-
0030729851
-
High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria
-
PID: 9369223, COI: 1:CAS:528:DyaK2sXms1eksro%3D
-
Korshunov SS, Skulachev VP, Starkov AA (1997) High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. FEBS Lett 416:15–18
-
(1997)
FEBS Lett
, vol.416
, pp. 15-18
-
-
Korshunov, S.S.1
Skulachev, V.P.2
Starkov, A.A.3
-
33
-
-
0034643340
-
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
-
PID: 10783895, COI: 1:CAS:528:DC%2BD3cXjtVals70%3D
-
Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, Yorek MA, Beebe D, Oates PJ, Hammes HP et al (2000) Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 404:787–790
-
(2000)
Nature
, vol.404
, pp. 787-790
-
-
Nishikawa, T.1
Edelstein, D.2
Du, X.L.3
Yamagishi, S.4
Matsumura, T.5
Kaneda, Y.6
Yorek, M.A.7
Beebe, D.8
Oates, P.J.9
Hammes, H.P.10
-
34
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia
-
PID: 16517405
-
Kim JW, Tchernyshyov I, Semenza GL, Dang CV (2006) HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab 3:177–185
-
(2006)
Cell Metab
, vol.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
35
-
-
43649104579
-
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
-
PID: 18281291, COI: 1:CAS:528:DC%2BD1cXksFagtbk%3D
-
Zhang H, Bosch-Marce M, Shimoda LA, Tan YS, Baek JH, Wesley JB, Gonzalez FJ, Semenza GL (2008) Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem 283:10892–10903
-
(2008)
J Biol Chem
, vol.283
, pp. 10892-10903
-
-
Zhang, H.1
Bosch-Marce, M.2
Shimoda, L.A.3
Tan, Y.S.4
Baek, J.H.5
Wesley, J.B.6
Gonzalez, F.J.7
Semenza, G.L.8
-
36
-
-
33947724515
-
HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells
-
PID: 17418790, COI: 1:CAS:528:DC%2BD2sXkvVeltLg%3D
-
Fukuda R, Zhang H, Kim JW, Shimoda L, Dang CV, Semenza GL (2007) HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells. Cell 129:111–122
-
(2007)
Cell
, vol.129
, pp. 111-122
-
-
Fukuda, R.1
Zhang, H.2
Kim, J.W.3
Shimoda, L.4
Dang, C.V.5
Semenza, G.L.6
-
37
-
-
70349478990
-
MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2
-
PID: 19808020, COI: 1:CAS:528:DC%2BD1MXhsFKltL3E
-
Chan SY, Zhang YY, Hemann C, Mahoney CE, Zweier JL, Loscalzo J (2009) MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2. Cell Metab 10:273–284
-
(2009)
Cell Metab
, vol.10
, pp. 273-284
-
-
Chan, S.Y.1
Zhang, Y.Y.2
Hemann, C.3
Mahoney, C.E.4
Zweier, J.L.5
Loscalzo, J.6
-
38
-
-
77951238575
-
Mitochondrial regulation of oxygen sensing
-
PID: 20204741, COI: 1:CAS:528:DC%2BC3cXhsFyjtrvO
-
Chandel NS (2010) Mitochondrial regulation of oxygen sensing. Adv Exp Med Biol 661:339–354
-
(2010)
Adv Exp Med Biol
, vol.661
, pp. 339-354
-
-
Chandel, N.S.1
-
39
-
-
24144467846
-
ROS: really involved in oxygen sensing
-
PID: 16054083, COI: 1:CAS:528:DC%2BD2MXlslajs7Y%3D
-
Kaelin WG Jr (2005) ROS: really involved in oxygen sensing. Cell Metab 1:357–358
-
(2005)
Cell Metab
, vol.1
, pp. 357-358
-
-
Kaelin, W.G.1
-
40
-
-
33745006163
-
Nitric oxide inhibits HIF-1alpha protein accumulation under hypoxic conditions: implication of 2-oxoglutarate and iron
-
PID: 16310922, COI: 1:CAS:528:DC%2BD28XmtVOlu7Y%3D
-
Kozhukhar AV, Yasinska IM, Sumbayev VV (2006) Nitric oxide inhibits HIF-1alpha protein accumulation under hypoxic conditions: implication of 2-oxoglutarate and iron. Biochimie 88:411–418
-
(2006)
Biochimie
, vol.88
, pp. 411-418
-
-
Kozhukhar, A.V.1
Yasinska, I.M.2
Sumbayev, V.V.3
-
41
-
-
28844462418
-
Role of poly(ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme
-
PID: 16356120, COI: 1:CAS:528:DC%2BD2MXhtlWht7%2FJ
-
Pacher P, Szabo C (2005) Role of poly(ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme. Antioxid Redox Signal 7:1568–1580
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 1568-1580
-
-
Pacher, P.1
Szabo, C.2
-
42
-
-
70349205438
-
Poly(ADP-ribose) polymerase-1 modulation of in vivo response of brain hypoxia-inducible factor-1 to hypoxia/reoxygenation is mediated by nitric oxide and factor inhibiting HIF
-
PID: 19656264, COI: 1:CAS:528:DC%2BD1MXht1ertLnF
-
Martinez-Romero R, Canuelo A, Martinez-Lara E, Javier Oliver F, Cardenas S, Siles E (2009) Poly(ADP-ribose) polymerase-1 modulation of in vivo response of brain hypoxia-inducible factor-1 to hypoxia/reoxygenation is mediated by nitric oxide and factor inhibiting HIF. J Neurochem 111:150–159
-
(2009)
J Neurochem
, vol.111
, pp. 150-159
-
-
Martinez-Romero, R.1
Canuelo, A.2
Martinez-Lara, E.3
Javier Oliver, F.4
Cardenas, S.5
Siles, E.6
-
43
-
-
84864323177
-
Novel links between HIFs, type 2 diabetes, and metabolic syndrome
-
PID: 22766319, COI: 1:CAS:528:DC%2BC38XpvVOqtb4%3D
-
Girgis CM, Cheng K, Scott CH, Gunton JE (2012) Novel links between HIFs, type 2 diabetes, and metabolic syndrome. Trends Endocrinol Metab 23:372–380
-
(2012)
Trends Endocrinol Metab
, vol.23
, pp. 372-380
-
-
Girgis, C.M.1
Cheng, K.2
Scott, C.H.3
Gunton, J.E.4
-
44
-
-
68949159760
-
Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue
-
PID: 19546236, COI: 1:CAS:528:DC%2BD1MXhtVSju7nO
-
Halberg N, Khan T, Trujillo ME, Wernstedt-Asterholm I, Attie AD, Sherwani S, Wang ZV, Landskroner-Eiger S, Dineen S, Magalang UJ et al (2009) Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue. Mol Cell Biol 29:4467–4483
-
(2009)
Mol Cell Biol
, vol.29
, pp. 4467-4483
-
-
Halberg, N.1
Khan, T.2
Trujillo, M.E.3
Wernstedt-Asterholm, I.4
Attie, A.D.5
Sherwani, S.6
Wang, Z.V.7
Landskroner-Eiger, S.8
Dineen, S.9
Magalang, U.J.10
-
45
-
-
77958508121
-
Adipose tissue-specific inhibition of hypoxia-inducible factor 1(alpha) induces obesity and glucose intolerance by impeding energy expenditure in mice
-
PID: 20716529, COI: 1:CAS:528:DC%2BC3cXht12nu7zE
-
Zhang X, Lam KS, Ye H, Chung SK, Zhou M, Wang Y, Xu A (2010) Adipose tissue-specific inhibition of hypoxia-inducible factor 1(alpha) induces obesity and glucose intolerance by impeding energy expenditure in mice. J Biol Chem 285:32869–32877
-
(2010)
J Biol Chem
, vol.285
, pp. 32869-32877
-
-
Zhang, X.1
Lam, K.S.2
Ye, H.3
Chung, S.K.4
Zhou, M.5
Wang, Y.6
Xu, A.7
-
46
-
-
84878313576
-
Prolyl hydroxylase domain protein 2 plays a critical role in diet-induced obesity and glucose intolerance
-
PID: 23630130, COI: 1:CAS:528:DC%2BC3sXosFKru78%3D
-
Matsuura H, Ichiki T, Inoue E, Nomura M, Miyazaki R, Hashimoto T, Ikeda J, Takayanagi R, Fong GH, Sunagawa K (2013) Prolyl hydroxylase domain protein 2 plays a critical role in diet-induced obesity and glucose intolerance. Circulation 127:2078–2087
-
(2013)
Circulation
, vol.127
, pp. 2078-2087
-
-
Matsuura, H.1
Ichiki, T.2
Inoue, E.3
Nomura, M.4
Miyazaki, R.5
Hashimoto, T.6
Ikeda, J.7
Takayanagi, R.8
Fong, G.H.9
Sunagawa, K.10
-
47
-
-
80053408653
-
Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet-fed mice
-
PID: 21873554, COI: 1:CAS:528:DC%2BC3MXhtl2is7zN
-
Jiang C, Qu A, Matsubara T, Chanturiya T, Jou W, Gavrilova O, Shah YM, Gonzalez FJ (2011) Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet-fed mice. Diabetes 60:2484–2495
-
(2011)
Diabetes
, vol.60
, pp. 2484-2495
-
-
Jiang, C.1
Qu, A.2
Matsubara, T.3
Chanturiya, T.4
Jou, W.5
Gavrilova, O.6
Shah, Y.M.7
Gonzalez, F.J.8
-
48
-
-
84856628731
-
Dietary obesity-associated Hif1alpha activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD + system
-
PID: 22302938, COI: 1:CAS:528:DC%2BC38XitlWgtLg%3D
-
Krishnan J, Danzer C, Simka T, Ukropec J, Walter KM, Kumpf S, Mirtschink P, Ukropcova B, Gasperikova D, Pedrazzini T et al (2012) Dietary obesity-associated Hif1alpha activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD + system. Genes Dev 26:259–270
-
(2012)
Genes Dev
, vol.26
, pp. 259-270
-
-
Krishnan, J.1
Danzer, C.2
Simka, T.3
Ukropec, J.4
Walter, K.M.5
Kumpf, S.6
Mirtschink, P.7
Ukropcova, B.8
Gasperikova, D.9
Pedrazzini, T.10
-
49
-
-
82355191512
-
Disruption of HIF-1alpha in hepatocytes impairs glucose metabolism in diet-induced obesity mice
-
PID: 22051049, COI: 1:CAS:528:DC%2BC3MXhsFeju7vI
-
Ochiai D, Goda N, Hishiki T, Kanai M, Senoo-Matsuda N, Soga T, Johnson RS, Yoshimura Y, Suematsu M (2011) Disruption of HIF-1alpha in hepatocytes impairs glucose metabolism in diet-induced obesity mice. Biochem Biophys Res Commun 415:445–449
-
(2011)
Biochem Biophys Res Commun
, vol.415
, pp. 445-449
-
-
Ochiai, D.1
Goda, N.2
Hishiki, T.3
Kanai, M.4
Senoo-Matsuda, N.5
Soga, T.6
Johnson, R.S.7
Yoshimura, Y.8
Suematsu, M.9
-
50
-
-
84900552363
-
Loss of HIF-1alpha impairs GLUT4 translocation and glucose uptake by the skeletal muscle cells
-
PID: 24619881, COI: 1:CAS:528:DC%2BC2cXptVCitLw%3D
-
Sakagami H, Makino Y, Mizumoto K, Isoe T, Takeda Y, Watanabe J, Fujita Y, Takiyama Y, Abiko A, Haneda M (2014) Loss of HIF-1alpha impairs GLUT4 translocation and glucose uptake by the skeletal muscle cells. Am J Physiol Endocrinol Metab 306:E1065–E1076
-
(2014)
Am J Physiol Endocrinol Metab
, vol.306
, pp. E1065-E1076
-
-
Sakagami, H.1
Makino, Y.2
Mizumoto, K.3
Isoe, T.4
Takeda, Y.5
Watanabe, J.6
Fujita, Y.7
Takiyama, Y.8
Abiko, A.9
Haneda, M.10
-
51
-
-
77955284188
-
The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism
-
PID: 20399150, COI: 1:CAS:528:DC%2BC3cXmtleis7g%3D
-
Zhang N, Fu Z, Linke S, Chicher J, Gorman JJ, Visk D, Haddad GG, Poellinger L, Peet DJ, Powell F et al (2010) The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism. Cell Metab 11:364–378
-
(2010)
Cell Metab
, vol.11
, pp. 364-378
-
-
Zhang, N.1
Fu, Z.2
Linke, S.3
Chicher, J.4
Gorman, J.J.5
Visk, D.6
Haddad, G.G.7
Poellinger, L.8
Peet, D.J.9
Powell, F.10
-
52
-
-
77950344913
-
Oxygen tension regulates pancreatic beta-cell differentiation through hypoxia-inducible factor 1alpha
-
PID: 20009089, COI: 1:CAS:528:DC%2BC3cXjslegtbc%3D
-
Heinis M, Simon MT, Ilc K, Mazure NM, Pouyssegur J, Scharfmann R, Duvillie B (2010) Oxygen tension regulates pancreatic beta-cell differentiation through hypoxia-inducible factor 1alpha. Diabetes 59:662–669
-
(2010)
Diabetes
, vol.59
, pp. 662-669
-
-
Heinis, M.1
Simon, M.T.2
Ilc, K.3
Mazure, N.M.4
Pouyssegur, J.5
Scharfmann, R.6
Duvillie, B.7
-
53
-
-
61749090485
-
Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice
-
PID: 19065050, COI: 1:CAS:528:DC%2BD1MXmtFChtQ%3D%3D
-
Cantley J, Selman C, Shukla D, Abramov AY, Forstreuter F, Esteban MA, Claret M, Lingard SJ, Clements M, Harten SK et al (2009) Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice. J Clin Invest 119:125–135
-
(2009)
J Clin Invest
, vol.119
, pp. 125-135
-
-
Cantley, J.1
Selman, C.2
Shukla, D.3
Abramov, A.Y.4
Forstreuter, F.5
Esteban, M.A.6
Claret, M.7
Lingard, S.J.8
Clements, M.9
Harten, S.K.10
-
54
-
-
56549094039
-
PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells
-
PID: 19056893, COI: 1:CAS:528:DC%2BD1cXhsVKhs7%2FI
-
Zehetner J, Danzer C, Collins S, Eckhardt K, Gerber PA, Ballschmieter P, Galvanovskis J, Shimomura K, Ashcroft FM, Thorens B et al (2008) PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells. Genes Dev 22:3135–3146
-
(2008)
Genes Dev
, vol.22
, pp. 3135-3146
-
-
Zehetner, J.1
Danzer, C.2
Collins, S.3
Eckhardt, K.4
Gerber, P.A.5
Ballschmieter, P.6
Galvanovskis, J.7
Shimomura, K.8
Ashcroft, F.M.9
Thorens, B.10
-
55
-
-
61949412026
-
A role for von Hippel-Lindau protein in pancreatic beta-cell function
-
PID: 19033400, COI: 1:CAS:528:DC%2BD1MXhslersbc%3D
-
Puri S, Cano DA, Hebrok M (2009) A role for von Hippel-Lindau protein in pancreatic beta-cell function. Diabetes 58:433–441
-
(2009)
Diabetes
, vol.58
, pp. 433-441
-
-
Puri, S.1
Cano, D.A.2
Hebrok, M.3
-
56
-
-
23744439083
-
Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes
-
PID: 16096055, COI: 1:CAS:528:DC%2BD2MXovV2qsrs%3D
-
Gunton JE, Kulkarni RN, Yim S, Okada T, Hawthorne WJ, Tseng YH, Roberson RS, Ricordi C, O’Connell PJ, Gonzalez FJ et al (2005) Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes. Cell 122:337–349
-
(2005)
Cell
, vol.122
, pp. 337-349
-
-
Gunton, J.E.1
Kulkarni, R.N.2
Yim, S.3
Okada, T.4
Hawthorne, W.J.5
Tseng, Y.H.6
Roberson, R.S.7
Ricordi, C.8
O’Connell, P.J.9
Gonzalez, F.J.10
-
57
-
-
77953001315
-
Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets
-
Cheng K, Ho K, Stokes R, Scott C, Lau SM, Hawthorne WJ, O’Connell PJ, Loudovaris T, Kay TW, Kulkarni RN et al (2010) Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets. J Clin Invest
-
(2010)
J Cl
-
-
Cheng, K.1
Ho, K.2
Stokes, R.3
Scott, C.4
Lau, S.M.5
Hawthorne, W.J.6
O’Connell, P.J.7
Loudovaris, T.8
Kay, T.W.9
Kulkarni, R.N.10
-
58
-
-
84863474509
-
Acute hypoxia induces apoptosis of pancreatic beta-cell by activation of the unfolded protein response and upregulation of CHOP
-
PID: 22695615, COI: 1:STN:280:DC%2BC38jhsFamuw%3D%3D
-
Zheng X, Wang X, Ma Z, Gupta Sunkari V, Botusan I, Takeda T, Bjorklund A, Inoue M, Catrina SB, Brismar K et al (2012) Acute hypoxia induces apoptosis of pancreatic beta-cell by activation of the unfolded protein response and upregulation of CHOP. Cell Death Dis 3:e322
-
(2012)
Cell Death Dis
, vol.3
, pp. e322
-
-
Zheng, X.1
Wang, X.2
Ma, Z.3
Gupta Sunkari, V.4
Botusan, I.5
Takeda, T.6
Bjorklund, A.7
Inoue, M.8
Catrina, S.B.9
Brismar, K.10
-
59
-
-
84872219305
-
Hypoxia-inducible factor 1alpha (HIF-1alpha) potentiates beta-cell survival after islet transplantation of human and mouse islets
-
Stokes RA, Cheng K, Deters N, Lau SM, Hawthorne WJ, O’Connell PJ, Stolp J, Grey S, Loudovaris T, Kay TW et al (2012) Hypoxia-inducible factor 1alpha (HIF-1alpha) potentiates beta-cell survival after islet transplantation of human and mouse islets. Cell Transplant
-
(2012)
Cell Transplant
-
-
Stokes, R.A.1
Cheng, K.2
Deters, N.3
Lau, S.M.4
Hawthorne, W.J.5
O’Connell, P.J.6
Stolp, J.7
Grey, S.8
Loudovaris, T.9
Kay, T.W.10
-
60
-
-
84862528769
-
Coenzyme Q10 prevents GDP-sensitive mitochondrial uncoupling, glomerular hyperfiltration and proteinuria in kidneys from db/db mice as a model of type 2 diabetes
-
Persson MF, Franzen S, Catrina SB, Dallner G, Hansell P, Brismar K, Palm F (2012) Coenzyme Q10 prevents GDP-sensitive mitochondrial uncoupling, glomerular hyperfiltration and proteinuria in kidneys from db/db mice as a model of type 2 diabetes. Diabetologia
-
(2012)
Diabetologia
-
-
Persson, M.F.1
Franzen, S.2
Catrina, S.B.3
Dallner, G.4
Hansell, P.5
Brismar, K.6
Palm, F.7
-
61
-
-
33645308317
-
Renoprotective properties of angiotensin receptor blockers beyond blood pressure lowering
-
PID: 16236804, COI: 1:CAS:528:DC%2BD28XhvFajsQ%3D%3D
-
Izuhara Y, Nangaku M, Inagi R, Tominaga N, Aizawa T, Kurokawa K, Van Ypersele De Strihou C, Miyata T (2005) Renoprotective properties of angiotensin receptor blockers beyond blood pressure lowering. J Am Soc Nephrol 16:3631–3641
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 3631-3641
-
-
Izuhara, Y.1
Nangaku, M.2
Inagi, R.3
Tominaga, N.4
Aizawa, T.5
Kurokawa, K.6
Van Ypersele De Strihou, C.7
Miyata, T.8
-
62
-
-
84883352068
-
Impact of the hypoxia-inducible factor-1 alpha (HIF-1alpha) Pro582Ser polymorphism on diabetes nephropathy
-
Gu HF, Zheng X, Abu Seman N, Gu T, Botusan IR, Sunkari VG, Lokman EF, Brismar K, Catrina SB (2012) Impact of the hypoxia-inducible factor-1 alpha (HIF-1alpha) Pro582Ser polymorphism on diabetes nephropathy. Diabetes care
-
(2012)
Diabetes care
-
-
Gu, H.F.1
Zheng, X.2
Abu Seman, N.3
Gu, T.4
Botusan, I.R.5
Sunkari, V.G.6
Lokman, E.F.7
Brismar, K.8
Catrina, S.B.9
-
63
-
-
77953688069
-
High glucose activates HIF-1-mediated signal transduction in glomerular mesangial cells through a carbohydrate response element binding protein
-
PID: 20375990, COI: 1:CAS:528:DC%2BC3cXnsVyhs7Y%3D
-
Isoe T, Makino Y, Mizumoto K, Sakagami H, Fujita Y, Honjo J, Takiyama Y, Itoh H, Haneda M (2010) High glucose activates HIF-1-mediated signal transduction in glomerular mesangial cells through a carbohydrate response element binding protein. Kidney Int 78(1):48–59
-
(2010)
Kidney Int
, vol.78
, Issue.1
, pp. 48-59
-
-
Isoe, T.1
Makino, Y.2
Mizumoto, K.3
Sakagami, H.4
Fujita, Y.5
Honjo, J.6
Takiyama, Y.7
Itoh, H.8
Haneda, M.9
-
64
-
-
33750866706
-
Altered gene expression related to glomerulogenesis and podocyte structure in early diabetic nephropathy of db/db mice and its restoration by pioglitazone
-
PID: 17003339, COI: 1:CAS:528:DC%2BD28XhtVGlsrbN
-
Makino H, Miyamoto Y, Sawai K, Mori K, Mukoyama M, Nakao K, Yoshimasa Y, Suga S (2006) Altered gene expression related to glomerulogenesis and podocyte structure in early diabetic nephropathy of db/db mice and its restoration by pioglitazone. Diabetes 55:2747–2756
-
(2006)
Diabetes
, vol.55
, pp. 2747-2756
-
-
Makino, H.1
Miyamoto, Y.2
Sawai, K.3
Mori, K.4
Mukoyama, M.5
Nakao, K.6
Yoshimasa, Y.7
Suga, S.8
-
65
-
-
84939898507
-
Effect of pioglitazone on diabetic nephropathy and expression of HIF-1alpha and VEGF in the renal tissues of type 2 diabetic rats
-
Xu X, Chen P, Zheng Q, Wang Y, Chen W (2011) Effect of pioglitazone on diabetic nephropathy and expression of HIF-1alpha and VEGF in the renal tissues of type 2 diabetic rats. Diabetes Res Clin Pract 60:981–92
-
(2011)
Diabetes Res Clin Pract
, vol.60
, pp. 981-992
-
-
Xu, X.1
Chen, P.2
Zheng, Q.3
Wang, Y.4
Chen, W.5
-
66
-
-
84866594039
-
Glucotoxicity induces glucose-6-phosphatase catalytic unit expression by acting on the interaction of HIF-1alpha with CREB-binding protein
-
PID: 22787137, COI: 1:CAS:528:DC%2BC38XhsVent7fL
-
Gautier-Stein A, Soty M, Chilloux J, Zitoun C, Rajas F, Mithieux G (2012) Glucotoxicity induces glucose-6-phosphatase catalytic unit expression by acting on the interaction of HIF-1alpha with CREB-binding protein. Diabetes 61:2451–2460
-
(2012)
Diabetes
, vol.61
, pp. 2451-2460
-
-
Gautier-Stein, A.1
Soty, M.2
Chilloux, J.3
Zitoun, C.4
Rajas, F.5
Mithieux, G.6
-
67
-
-
33646358954
-
High glucose blunts vascular endothelial growth factor response to hypoxia via the oxidative stress-regulated hypoxia-inducible factor/hypoxia-responsible element pathway
-
PID: 16597689, COI: 1:CAS:528:DC%2BD28XkvVKrsbk%3D
-
Katavetin P, Miyata T, Inagi R, Tanaka T, Sassa R, Ingelfinger JR, Fujita T, Nangaku M (2006) High glucose blunts vascular endothelial growth factor response to hypoxia via the oxidative stress-regulated hypoxia-inducible factor/hypoxia-responsible element pathway. J Am Soc Nephrol 17:1405–1413
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1405-1413
-
-
Katavetin, P.1
Miyata, T.2
Inagi, R.3
Tanaka, T.4
Sassa, R.5
Ingelfinger, J.R.6
Fujita, T.7
Nangaku, M.8
-
68
-
-
42949165144
-
Cobalt ameliorates renal injury in an obese, hypertensive type 2 diabetes rat model
-
PID: 17967803, COI: 1:CAS:528:DC%2BD1cXjs12lsLY%3D
-
Ohtomo S, Nangaku M, Izuhara Y, Takizawa S, Strihou CY, Miyata T (2008) Cobalt ameliorates renal injury in an obese, hypertensive type 2 diabetes rat model. Nephrol Dial Transplant 23:1166–1172
-
(2008)
Nephrol Dial Transplant
, vol.23
, pp. 1166-1172
-
-
Ohtomo, S.1
Nangaku, M.2
Izuhara, Y.3
Takizawa, S.4
Strihou, C.Y.5
Miyata, T.6
-
69
-
-
80054976363
-
Tubular deficiency of von Hippel-Lindau attenuates renal disease progression in anti-GBM glomerulonephritis
-
PID: 21925138, COI: 1:CAS:528:DC%2BC3MXhsFCmu7zN
-
Theilig F, Enke AK, Scolari B, Polzin D, Bachmann S, Koesters R (2011) Tubular deficiency of von Hippel-Lindau attenuates renal disease progression in anti-GBM glomerulonephritis. Am J Pathol 179:2177–88
-
(2011)
Am J Pathol
, vol.179
, pp. 2177-2188
-
-
Theilig, F.1
Enke, A.K.2
Scolari, B.3
Polzin, D.4
Bachmann, S.5
Koesters, R.6
-
70
-
-
20944446740
-
Hypoxia-inducible factor-1alpha is involved in the attenuation of experimentally induced rat glomerulonephritis
-
PID: 15775723, COI: 1:CAS:528:DC%2BD2MXkt1ShtL0%3D
-
Kudo Y, Kakinuma Y, Mori Y, Morimoto N, Karashima T, Furihata M, Sato T, Shuin T, Sugiura T (2005) Hypoxia-inducible factor-1alpha is involved in the attenuation of experimentally induced rat glomerulonephritis. Nephron Exp Nephrol 100:e95–103
-
(2005)
Nephron Exp Nephrol
, vol.100
, pp. e95-e103
-
-
Kudo, Y.1
Kakinuma, Y.2
Mori, Y.3
Morimoto, N.4
Karashima, T.5
Furihata, M.6
Sato, T.7
Shuin, T.8
Sugiura, T.9
-
71
-
-
84885005460
-
Deal watch: astraZeneca bets on FibroGen’s anaemia drug
-
PID: 24080688
-
Flight MH (2013) Deal watch: astraZeneca bets on FibroGen’s anaemia drug. Nat Rev Drug Discov 12:730
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 730
-
-
Flight, M.H.1
-
72
-
-
84867539657
-
HIF-1alpha in the heart: a double agent?
-
PID: 22673235
-
Hashmi S, Al-Salam S (2012) HIF-1alpha in the heart: a double agent? Cardiol Rev 20:268–73
-
(2012)
Cardiol Rev
, vol.20
, pp. 268-273
-
-
Hashmi, S.1
Al-Salam, S.2
-
73
-
-
0033602795
-
Glycometabolic state at admission: important risk marker of mortality in conventionally treated patients with diabetes mellitus and acute myocardial infarction: long-term results from the diabetes and insulin-glucose infusion in acute myocardial infarction (DIGAMI) study
-
PID: 10338454, COI: 1:CAS:528:DyaK1MXjvVKmtrw%3D
-
Malmberg K, Norhammar A, Wedel H, Ryden L (1999) Glycometabolic state at admission: important risk marker of mortality in conventionally treated patients with diabetes mellitus and acute myocardial infarction: long-term results from the diabetes and insulin-glucose infusion in acute myocardial infarction (DIGAMI) study. Circulation 99:2626–2632
-
(1999)
Circulation
, vol.99
, pp. 2626-2632
-
-
Malmberg, K.1
Norhammar, A.2
Wedel, H.3
Ryden, L.4
-
74
-
-
0025900699
-
In-hospital prognosis of patients with fasting hyperglycemia after first myocardial infarction
-
PID: 1954815
-
O’Sullivan JJ, Conroy RM, Robinson K, Hickey N, Mulcahy R (1991) In-hospital prognosis of patients with fasting hyperglycemia after first myocardial infarction. Diabetes Care 14:758–760
-
(1991)
Diabetes Care
, vol.14
, pp. 758-760
-
-
O’Sullivan, J.J.1
Conroy, R.M.2
Robinson, K.3
Hickey, N.4
Mulcahy, R.5
-
75
-
-
4344593331
-
Expression of angiogenic factors during acute coronary syndromes in human type 2 diabetes
-
PID: 15331549, COI: 1:CAS:528:DC%2BD2cXns1Shs7Y%3D
-
Marfella R, Esposito K, Nappo F, Siniscalchi M, Sasso FC, Portoghese M, Di Marino MP, Baldi A, Cuzzocrea S, Di Filippo C et al (2004) Expression of angiogenic factors during acute coronary syndromes in human type 2 diabetes. Diabetes 53:2383–2391
-
(2004)
Diabetes
, vol.53
, pp. 2383-2391
-
-
Marfella, R.1
Esposito, K.2
Nappo, F.3
Siniscalchi, M.4
Sasso, F.C.5
Portoghese, M.6
Di Marino, M.P.7
Baldi, A.8
Cuzzocrea, S.9
Di Filippo, C.10
-
76
-
-
84880401475
-
N-acetylcysteine and allopurinol confer synergy in attenuating myocardial ischemia injury via restoring HIF-1alpha/HO-1 signaling in diabetic rats
-
PID: 23874823, COI: 1:CAS:528:DC%2BC3sXht1WmtLrJ
-
Mao X, Wang T, Liu Y, Irwin MG, Ou JS, Liao XL, Gao X, Xu Y, Ng KF, Vanhoutte PM et al (2013) N-acetylcysteine and allopurinol confer synergy in attenuating myocardial ischemia injury via restoring HIF-1alpha/HO-1 signaling in diabetic rats. PLoS ONE 8:e68949
-
(2013)
PLoS ONE
, vol.8
, pp. e68949
-
-
Mao, X.1
Wang, T.2
Liu, Y.3
Irwin, M.G.4
Ou, J.S.5
Liao, X.L.6
Gao, X.7
Xu, Y.8
Ng, K.F.9
Vanhoutte, P.M.10
-
77
-
-
66049097308
-
Activation of a HIF1alpha-PPARgamma axis underlies the integration of glycolytic and lipid anabolic pathways in pathologic cardiac hypertrophy
-
PID: 19490906, COI: 1:CAS:528:DC%2BD1MXps1ensro%3D
-
Krishnan J, Suter M, Windak R, Krebs T, Felley A, Montessuit C, Tokarska-Schlattner M, Aasum E, Bogdanova A, Perriard E et al (2009) Activation of a HIF1alpha-PPARgamma axis underlies the integration of glycolytic and lipid anabolic pathways in pathologic cardiac hypertrophy. Cell Metab 9:512–524
-
(2009)
Cell Metab
, vol.9
, pp. 512-524
-
-
Krishnan, J.1
Suter, M.2
Windak, R.3
Krebs, T.4
Felley, A.5
Montessuit, C.6
Tokarska-Schlattner, M.7
Aasum, E.8
Bogdanova, A.9
Perriard, E.10
-
78
-
-
34548590934
-
Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: a meta-analysis of randomized trials
-
PID: 17848652, COI: 1:CAS:528:DC%2BD2sXhtVGmtL3J
-
Lincoff AM, Wolski K, Nicholls SJ, Nissen SE (2007) Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: a meta-analysis of randomized trials. JAMA 298:1180–1188
-
(2007)
JAMA
, vol.298
, pp. 1180-1188
-
-
Lincoff, A.M.1
Wolski, K.2
Nicholls, S.J.3
Nissen, S.E.4
-
79
-
-
34250212715
-
Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
-
PID: 17517853, COI: 1:CAS:528:DC%2BD2sXms1SisrY%3D
-
Nissen SE, Wolski K (2007) Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med 356:2457–2471
-
(2007)
N Engl J Med
, vol.356
, pp. 2457-2471
-
-
Nissen, S.E.1
Wolski, K.2
-
80
-
-
84861891920
-
MicroRNA dysregulation in diabetic ischemic heart failure patients
-
PID: 22427379, COI: 1:CAS:528:DC%2BC38XotlKjsro%3D
-
Greco S, Fasanaro P, Castelvecchio S, D’Alessandra Y, Arcelli D, Di Donato M, Malavazos A, Capogrossi MC, Menicanti L, Martelli F (2012) MicroRNA dysregulation in diabetic ischemic heart failure patients. Diabetes 61:1633–1641
-
(2012)
Diabetes
, vol.61
, pp. 1633-1641
-
-
Greco, S.1
Fasanaro, P.2
Castelvecchio, S.3
D’Alessandra, Y.4
Arcelli, D.5
Di Donato, M.6
Malavazos, A.7
Capogrossi, M.C.8
Menicanti, L.9
Martelli, F.10
-
81
-
-
77954608736
-
Cardiac-specific overexpression of HIF-1(alpha) prevents deterioration of glycolytic pathway and cardiac remodeling in streptozotocin-induced diabetic mice
-
PID: 20566749, COI: 1:CAS:528:DC%2BC3cXpslCrsr4%3D
-
Xue W, Cai L, Tan Y, Thistlethwaite P, Kang YJ, Li X, Feng W (2010) Cardiac-specific overexpression of HIF-1(alpha) prevents deterioration of glycolytic pathway and cardiac remodeling in streptozotocin-induced diabetic mice. Am J Pathol 177:97–105
-
(2010)
Am J Pathol
, vol.177
, pp. 97-105
-
-
Xue, W.1
Cai, L.2
Tan, Y.3
Thistlethwaite, P.4
Kang, Y.J.5
Li, X.6
Feng, W.7
-
82
-
-
39749087544
-
Hypoxia inducible factor-1 upregulates adiponectin in diabetic mouse hearts and attenuates post-ischemic injury
-
PID: 18287886, COI: 1:CAS:528:DC%2BD1cXit1yhtbk%3D
-
Natarajan R, Salloum FN, Fisher BJ, Kukreja RC, Fowler AA 3rd (2008) Hypoxia inducible factor-1 upregulates adiponectin in diabetic mouse hearts and attenuates post-ischemic injury. J Cardiovasc Pharmacol 51:178–187
-
(2008)
J Cardiovasc Pharmacol
, vol.51
, pp. 178-187
-
-
Natarajan, R.1
Salloum, F.N.2
Fisher, B.J.3
Kukreja, R.C.4
Fowler, A.A.5
-
83
-
-
77954165358
-
Modified multipotent stromal cells with epidermal growth factor restore vasculogenesis and blood flow in ischemic hind-limb of type II diabetic mice
-
PID: 20440273, COI: 1:CAS:528:DC%2BC3cXotFeisbg%3D
-
Amin AH, Abd Elmageed ZY, Nair D, Partyka MI, Kadowitz PJ, Belmadani S, Matrougui K (2010) Modified multipotent stromal cells with epidermal growth factor restore vasculogenesis and blood flow in ischemic hind-limb of type II diabetic mice. Lab Invest 90:985–96
-
(2010)
Lab Invest
, vol.90
, pp. 985-996
-
-
Amin, A.H.1
Abd Elmageed, Z.Y.2
Nair, D.3
Partyka, M.I.4
Kadowitz, P.J.5
Belmadani, S.6
Matrougui, K.7
-
84
-
-
72449157983
-
Decreased mobilization of endothelial progenitor cells contributes to impaired neovascularization in diabetes
-
PID: 19558529, COI: 1:CAS:528:DC%2BD1MXhsVSkur%2FP
-
Kang LN, Chen Q, Wang L, Gao L, Meng K, Chen JH, Ferro A, Xu B (2009) Decreased mobilization of endothelial progenitor cells contributes to impaired neovascularization in diabetes. Clin Exp Pharmacol Physiol 36:E47–E56
-
(2009)
Clin Exp Pharmacol Physiol
, vol.36
, pp. E47-E56
-
-
Kang, L.N.1
Chen, Q.2
Wang, L.3
Gao, L.4
Meng, K.5
Chen, J.H.6
Ferro, A.7
Xu, B.8
-
85
-
-
73249140173
-
Adenoviral transfer of HIF-1alpha enhances vascular responses to critical limb ischemia in diabetic mice
-
PID: 19841279, COI: 1:CAS:528:DC%2BD1MXhsVKmtLvM
-
Sarkar K, Fox-Talbot K, Steenbergen C, Bosch-Marce M, Semenza GL (2009) Adenoviral transfer of HIF-1alpha enhances vascular responses to critical limb ischemia in diabetic mice. Proc Natl Acad Sci U S A 106:18769–18774
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 18769-18774
-
-
Sarkar, K.1
Fox-Talbot, K.2
Steenbergen, C.3
Bosch-Marce, M.4
Semenza, G.L.5
-
86
-
-
84939905173
-
-
Stockholm: Sweden
-
Sakagami H, Makino Y, Mizumoto K, Isoe T, Takeda J, Watanabe J, Fujita Y, Takiyama Y, Abiko A, Haneda M (2010) Knockdown of hypoxia-inducible factor-1 alpha ameliorates insulin-stimulated glucose uptake in the skeletal muscle cellsEASD meeting, Stockholm, Sweden
-
(2010)
Knockdown of hypoxia-inducible factor-1 alpha ameliorates insulin-stimulated glucose uptake in the skeletal muscle cellsEASD meeting
-
-
Sakagami, H.1
Makino, Y.2
Mizumoto, K.3
Isoe, T.4
Takeda, J.5
Watanabe, J.6
Fujita, Y.7
Takiyama, Y.8
Abiko, A.9
Haneda, M.10
-
87
-
-
50949099761
-
The role of HIF-1 in hypoxic response in the skeletal muscle
-
PID: 18269201
-
Mason S, Johnson RS (2007) The role of HIF-1 in hypoxic response in the skeletal muscle. Adv Exp Med Biol 618:229–244
-
(2007)
Adv Exp Med Biol
, vol.618
, pp. 229-244
-
-
Mason, S.1
Johnson, R.S.2
-
88
-
-
78650750309
-
PGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber types
-
PID: 21106753, COI: 1:CAS:528:DC%2BC3cXhs1WjsrbO
-
Rasbach KA, Gupta RK, Ruas JL, Wu J, Naseri E, Estall JL, Spiegelman BM (2010) PGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber types. Proc Natl Acad Sci U S A 107:21866–21871
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 21866-21871
-
-
Rasbach, K.A.1
Gupta, R.K.2
Ruas, J.L.3
Wu, J.4
Naseri, E.5
Estall, J.L.6
Spiegelman, B.M.7
-
89
-
-
0034326273
-
Coordinate up-regulation of hypoxia inducible factor (HIF)-1alpha and HIF-1 target genes during multi-stage epidermal carcinogenesis and wound healing
-
PID: 11085544, COI: 1:CAS:528:DC%2BD3cXotV2ltr4%3D
-
Elson DA, Ryan HE, Snow JW, Johnson R, Arbeit JM (2000) Coordinate up-regulation of hypoxia inducible factor (HIF)-1alpha and HIF-1 target genes during multi-stage epidermal carcinogenesis and wound healing. Cancer Res 60:6189–6195
-
(2000)
Cancer Res
, vol.60
, pp. 6189-6195
-
-
Elson, D.A.1
Ryan, H.E.2
Snow, J.W.3
Johnson, R.4
Arbeit, J.M.5
-
90
-
-
51449105857
-
Age-dependent impairment of HIF-1alpha expression in diabetic mice: correction with electroporation-facilitated gene therapy increases wound healing, angiogenesis, and circulating angiogenic cells
-
PID: 18506785, COI: 1:CAS:528:DC%2BD1cXht1eltrnM
-
Liu L, Marti GP, Wei X, Zhang X, Zhang H, Liu YV, Nastai M, Semenza GL, Harmon JW (2008) Age-dependent impairment of HIF-1alpha expression in diabetic mice: correction with electroporation-facilitated gene therapy increases wound healing, angiogenesis, and circulating angiogenic cells. J Cell Physiol 217:319–327
-
(2008)
J Cell Physiol
, vol.217
, pp. 319-327
-
-
Liu, L.1
Marti, G.P.2
Wei, X.3
Zhang, X.4
Zhang, H.5
Liu, Y.V.6
Nastai, M.7
Semenza, G.L.8
Harmon, J.W.9
-
91
-
-
79960103014
-
Topical prolyl hydroxylase domain-2 silencing improves diabetic murine wound closure
-
Wetterau M, George F, Weinstein A, Nguyen PD, Tutela JP, Knobel D, Cohen Ba O, Warren SM, Saadeh PB (2011) Topical prolyl hydroxylase domain-2 silencing improves diabetic murine wound closure. Wound repair and regen: official publ of the Wound Healing Soc [and] the Eur Tissue Repair Soc 19:481–486
-
(2011)
Wound repair and regen: official publ of the Wound Healing Soc [and] the Eur Tissue Repair Soc
, vol.19
, pp. 481-486
-
-
Wetterau, M.1
George, F.2
Weinstein, A.3
Nguyen, P.D.4
Tutela, J.P.5
Knobel, D.6
Cohen Ba, O.7
Warren, S.M.8
Saadeh, P.B.9
-
92
-
-
84879601468
-
Deferoxamine enhances neovascularization and accelerates wound healing in diabetic rats via the accumulation of hypoxia-inducible factor-1alpha
-
Hou Z, Nie C, Si Z, Ma Y (2013) Deferoxamine enhances neovascularization and accelerates wound healing in diabetic rats via the accumulation of hypoxia-inducible factor-1alpha. Diabetes Res Clin Pract
-
(2013)
Diabetes Res Cl
-
-
Hou, Z.1
Nie, C.2
Si, Z.3
Ma, Y.4
-
93
-
-
0030010417
-
Retinal blood flow changes in patients with insulin-dependent diabetes mellitus and no diabetic retinopathy
-
PID: 8603873, COI: 1:STN:280:DyaK287otFCntA%3D%3D
-
Bursell SE, Clermont AC, Kinsley BT, Simonson DC, Aiello LM, Wolpert HA (1996) Retinal blood flow changes in patients with insulin-dependent diabetes mellitus and no diabetic retinopathy. Invest Ophthalmol Vis Sci 37:886–897
-
(1996)
Invest Ophthalmol Vis Sci
, vol.37
, pp. 886-897
-
-
Bursell, S.E.1
Clermont, A.C.2
Kinsley, B.T.3
Simonson, D.C.4
Aiello, L.M.5
Wolpert, H.A.6
-
94
-
-
0027942607
-
Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders
-
PID: 7526212, COI: 1:STN:280:DyaK2M%2FlvFamsA%3D%3D
-
Aiello LP, Avery RL, Arrigg PG, Keyt BA, Jampel HD, Shah ST, Pasquale LR, Thieme H, Iwamoto MA, Park JE et al (1994) Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med 331:1480–1487
-
(1994)
N Engl J Med
, vol.331
, pp. 1480-1487
-
-
Aiello, L.P.1
Avery, R.L.2
Arrigg, P.G.3
Keyt, B.A.4
Jampel, H.D.5
Shah, S.T.6
Pasquale, L.R.7
Thieme, H.8
Iwamoto, M.A.9
Park, J.E.10
-
95
-
-
78049232810
-
A comparison of hypoxia-inducible factor-alpha in surgically exised neovascular membranes of patients with diabetes compared with epiretinal membranes in nondiabetic patients
-
Lim JI, Spee C, Hinton DR (2010) A comparison of hypoxia-inducible factor-alpha in surgically exised neovascular membranes of patients with diabetes compared with epiretinal membranes in nondiabetic patients. Retina
-
(2010)
Retina
-
-
Lim, J.I.1
Spee, C.2
Hinton, D.R.3
-
96
-
-
4444317558
-
Altered insulin signaling in retinal tissue in diabetic states
-
PID: 15201286, COI: 1:CAS:528:DC%2BD2cXntFSnt7w%3D
-
Kondo T, Kahn CR (2004) Altered insulin signaling in retinal tissue in diabetic states. J Biol Chem 279:37997–38006
-
(2004)
J Biol Chem
, vol.279
, pp. 37997-38006
-
-
Kondo, T.1
Kahn, C.R.2
-
97
-
-
48649089571
-
Expression of erythropoietin and its receptor in the human retina: a comparative study of diabetic and nondiabetic subjects
-
PID: 18332162
-
Garcia-Ramirez M, Hernandez C, Simo R (2008) Expression of erythropoietin and its receptor in the human retina: a comparative study of diabetic and nondiabetic subjects. Diabetes Care 31:1189–1194
-
(2008)
Diabetes Care
, vol.31
, pp. 1189-1194
-
-
Garcia-Ramirez, M.1
Hernandez, C.2
Simo, R.3
-
98
-
-
0037008770
-
Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway
-
PID: 12032158, COI: 1:CAS:528:DC%2BD38XlvFKgtL0%3D
-
Treins C, Giorgetti-Peraldi S, Murdaca J, Semenza GL, Van Obberghen E (2002) Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway. J Biol Chem 277:27975–27981
-
(2002)
J Biol Chem
, vol.277
, pp. 27975-27981
-
-
Treins, C.1
Giorgetti-Peraldi, S.2
Murdaca, J.3
Semenza, G.L.4
Van Obberghen, E.5
-
99
-
-
0036196081
-
Acute intensive insulin therapy exacerbates diabetic blood-retinal barrier breakdown via hypoxia-inducible factor-1alpha and VEGF
-
COI: 1:CAS:528:DC%2BD38Xit1Gnsrs%3D
-
Poulaki V, Qin W, Joussen AM, Hurlbut P, Wiegand SJ, Rudge J, Yancopoulos GD, Adamis AP (2002) Acute intensive insulin therapy exacerbates diabetic blood-retinal barrier breakdown via hypoxia-inducible factor-1alpha and VEGF. JClinInvest 109:805–815
-
(2002)
JClinInvest
, vol.109
, pp. 805-815
-
-
Poulaki, V.1
Qin, W.2
Joussen, A.M.3
Hurlbut, P.4
Wiegand, S.J.5
Rudge, J.6
Yancopoulos, G.D.7
Adamis, A.P.8
-
100
-
-
79953286300
-
Role of HIF-1alpha in maternal hyperglycemia-induced embryonic vasculopathy
-
Yang P, Reece EA (2011) Role of HIF-1alpha in maternal hyperglycemia-induced embryonic vasculopathy. Am J Obstet Gynecol 204(332):e331–337
-
(2011)
Am J Obstet Gynecol
, vol.204
, Issue.332
, pp. e331-e337
-
-
Yang, P.1
Reece, E.A.2
|