Deferoxamine enhances neovascularization and accelerates wound healing in diabetic rats via the accumulation of hypoxia-inducible factor-1α

Diabetes Research and Clinical Practice

Volumn 101, Issue 1, 2013, Pages 62-71

  Hou, Zhanjiang ^a   Nie, Chunlei ^b   Si, Zhenxing ^a   Ma, Yongsheng ^a  

^a THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Deferoxamine; Diabetic wound; Hypoxia inducible factor 1 ; Vascularization

Indexed keywords

DEFEROXAMINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; RP 75747; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VASCULOTROPIN; SIDEROPHORE; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFICACY; DRUG MECHANISM; ENDOTHELIUM CELL; EPITHELIZATION; GRANULATION TISSUE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; UPREGULATION; WOUND HEALING; WOUND HEALING IMPAIRMENT; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; GENETICS; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; SPRAGUE DAWLEY RAT; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; DEFEROXAMINE; DIABETES MELLITUS, EXPERIMENTAL; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALE; NEOVASCULARIZATION, PATHOLOGIC; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; SIDEROPHORES; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

EID: 84879601468     PISSN: 01688227     EISSN: 18728227     Source Type: Journal    
DOI: 10.1016/j.diabres.2013.04.012     Document Type: Article

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