Glucotoxicity induces glucose-6-phosphatase catalytic unit expression by acting on the interaction of HIF-1α with CREB-binding protein

Diabetes

Volumn 61, Issue 10, 2012, Pages 2451-2460

  Gautier Stein, Amandine ^a,b,c   Soty, Maud ^a,b,c   Chilloux, Julien ^a,b,c   Zitoun, Carine ^a,b,c   Rajas, Fabienne ^a,b,c   Mithieux, Gilles ^a,b,c  

^a INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE   (France)

^b UNIVERSITÉ DE LYON   (France)

^c UNIVERSITÉ LYON 1   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GLUCOSE; GLUCOSE 6 PHOSPHATASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TROLOX C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GLUCONEOGENESIS; HEPATOMA CELL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; LIVER CELL; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INTERACTION; TOXICITY; TRANSCRIPTION REGULATION; TUMOR CELL LINE;

ANIMALS; CELL LINE; CELLS, CULTURED; CREB-BINDING PROTEIN; GLUCOSE; GLUCOSE-6-PHOSPHATASE; HEPATOCYTES; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIVER; MICE; PROMOTER REGIONS, GENETIC; REACTIVE OXYGEN SPECIES;

EID: 84866594039     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-0986     Document Type: Article

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