Disruption of HIF-1α in hepatocytes impairs glucose metabolism in diet-induced obesity mice

Biochemical and Biophysical Research Communications

Volumn 415, Issue 3, 2011, Pages 445-449

  Ochiai, Daigo ^a   Goda, Nobuhito ^b,c   Hishiki, Takako ^a   Kanai, Mai ^c   Senoo Matsuda, Nanami ^b,c   Soga, Tomoyoshi ^a   Johnson, Randall S ^d   Yoshimura, Yasunori ^a   Suematsu, Makoto ^a,b  

^a KEIO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c WASEDA UNIVERSITY   (Japan)

^d SECTION OF MOLECULAR BIOLOGY   (United States)

Author keywords

Carbohydrate metabolism; Diabetes; Glucokinase; HIF 1; Hypoxia; Liver

Indexed keywords

GLUCOKINASE; GLUCOSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INSULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; HYPERGLYCEMIA; HYPOXEMIA; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LIPID DIET; LIVER CELL; MALE; MOUSE; NONHUMAN; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; DIABETES MELLITUS; DIET, HIGH-FAT; GLUCOSE; GLUCOSE TOLERANCE TEST; HEPATOCYTES; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INSULIN RESISTANCE; MICE; MICE, OBESE; OBESITY; SUCROSE;

MUS;

EID: 82355191512     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.10.089     Document Type: Article

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