Cobalt ameliorates renal injury in an obese, hypertensive type 2 diabetes rat model

Nephrology Dialysis Transplantation

Volumn 23, Issue 4, 2008, Pages 1166-1172

  Ohtomo, Shuichi ^a   Nangaku, Masaomi ^b   Izuhara, Yuko ^a   Takizawa, Shunya ^a   Strihou, Charles Van Ypersele De ^c   Miyata, Toshio ^a,d  

^a TOKAI UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^d TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Chronic hypoxia; Cobalt chloride; Diabetic nephropathy; Hypoxia inducible factor; Oxidative stress

Indexed keywords

COBALT CHLORIDE; CONNECTIVE TISSUE GROWTH FACTOR; ERYTHROPOIETIN; HEME OXYGENASE 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; PENTOSIDINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN; ADVANCED GLYCATION END PRODUCT; ANTIMUTAGENIC AGENT; ARGININE; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; COBALT; DRUG DERIVATIVE; ENDOTHELIAL PAS DOMAIN CONTAINING PROTEIN 1; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; HIF1A PROTEIN, RAT; IMMEDIATE EARLY PROTEIN; LYSINE; MESSENGER RNA; SIGNAL PEPTIDE; SOMATOMEDIN BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC HYPERTENSION; DIABETIC NEPHROPATHY; DRUG EFFECT; GLYCATION; HISTOPATHOLOGY; HYPERGLYCEMIA; HYPERLIPIDEMIA; KIDNEY INJURY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIA; RAT; ANIMAL; ANOXIA; BIOSYNTHESIS; BLOOD PRESSURE; COMPARATIVE STUDY; DISEASE COURSE; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERTENSION; KIDNEY; MALE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; SPONTANEOUSLY HYPERTENSIVE RAT; VASCULARIZATION; WESTERN BLOTTING;

ANIMALS; ANOXIA; ANTIMUTAGENIC AGENTS; ARGININE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BLOOD PRESSURE; BLOTTING, WESTERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COBALT; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; DISEASE PROGRESSION; GENE EXPRESSION; GLYCOSYLATION END PRODUCTS, ADVANCED; HYPERTENSION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMEDIATE-EARLY PROTEINS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY; LYSINE; MALE; NADPH OXIDASE; OBESITY; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; RATS; RATS, INBRED SHR; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA;

EID: 42949165144     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfm715     Document Type: Article

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