Neurovascular control and neurogenic inflammation in diabetes

Diabetes/Metabolism Research and Reviews

Volumn 24, Issue SUPPL. 1, 2008, Pages

  Schaper, Nicolaas C ^a   Huijberts, M ^a   Pickwell, K ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Charcot neuro osteoarthropathy; Diabetes; Foot ulcer; Microcirculation; Neurogenic inflammation; Neuropathy

Indexed keywords

ACETYLCHOLINE; CALCITONIN GENE RELATED PEPTIDE; SUBSTANCE P; TUMOR NECROSIS FACTOR ALPHA;

ANALGESIA (SENSORY DYSFUNCTION); BLOOD VESSEL REACTIVITY; CAPILLARY FLOW; CARDIOVASCULAR RISK; CONFERENCE PAPER; DENERVATION; DIABETES MELLITUS; DIABETIC FOOT; DIABETIC NEUROPATHY; DISEASE CONTROL; DISEASE EXACERBATION; DISEASE PREDISPOSITION; ENZYME ACTIVITY; FILTRATION; HOMEOSTASIS; HUMAN; MICROVASCULAR ISCHEMIA; NEUROGENIC INFLAMMATION; NEUROPATHIC JOINT DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; RISK ASSESSMENT; TISSUE INJURY;

BLOOD FLOW VELOCITY; DIABETIC NEUROPATHIES; HUMANS; INFLAMMATION; MICROCIRCULATION;

EID: 44949232374     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.862     Document Type: Conference Paper

References (41)

1. Boulton AJ. The diabetic foot: from art to science. The 18th Camillo Golgi lecture. Diabetologia 2004; 47: 1343-1353.
2. Steinhoff M, Sander S, Seeliger S, Ansel JC, Schmelz M, Luger T. Modern aspects of cutaneous neurogenic inflammation. Arch Dermatol 2003; 139: 1479-1488.
3. Shepherd AJ, Downing JE, Miyan JA. Without nerves, immunology remains incomplete -in vivo veritas. Immunology 2005; 116: 145-163.
4. Purewal TS, Goss DE, Watkins PJ, Edmonds ME. Lower limb venous pressure in diabetic neuropathy. Diabetes Care 1995; 18: 377-381.
5. Leftandt JD, Bosma E, Oomen PH, et al. Sympathetic mediated vasomotion and skin capillary permeability in diabetic patients with peripheral neuropathy. Diabetologia 2003; 46: 40-47.
6. Lower RF, Kenzora JE. The diabetic neuropathic foot: a triple crush syndrome-measurement of compartmental pressures of normal and diabetic feet. Orthopedics 1994; 17: 241-248.
7. Ragheb J, Buggy DJ. Editorial III: Tissue oxygen tension (PTO2) in anaesthesia and perioperative medicine. Br J Anaesth 2004; 92: 464-468.
8. Netten PM, Wollersheim H, Thien T, Lutterman JA. Skin microcirculation of the foot in diabetic neuropathy. Clin Sci 1996; 91:559-565.
9. Netten PM, Wollersheim H, Gielen MJ, Den Arend JA, Lutterman JA, Thien T. The influence of u1nar nerve blockade on skin microvascular blood flow. Eur J Clin Invest 1995; 25: 515-522.
10. Nabuurs-Franssen MH, Houben AJ, Tooke JE, Schaper NC. The effect of polyneuropathy on foot microcirculation in Type II diabetes. Diabetologia 2002; 45: 1164-1171.
11. Kim JA, Montagnani M, Koh KK, Quon MJ. Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation 2006; 113: 1888-1904.
12. Rayman G, Malik RA, Sharma AK, Day JL. Microvascular response to tissue injury and capillary ultrastructure in the foot skin of type 1 diabetic patients. Clin Sci 1995; 89: 467-474.
13. Huvers FC, De Leeuw PW, Houben AJ, et al. Endothelium-dependent vasodilatation, plasma markers of endothelial function, and adrenergic vasoconstrictor responses in type 1 diabetes under near-normoglycemic conditions. Diabetes 1999; 48: 1300-1307.
14. Khan F, Elhadd TA, Greene SA, Belch JJ. Impaired skin microvascular function in children, adolescents, and young adults with type 1 diabetes. Diabetes Care 2000; 23: 215-220.
15. Forst T, Pfutzner A, Kunt T, et al. Skin microcirculation in patients with type I diabetes with and without neuropathy after neurovascular stimulation. Clin Sci 1998; 94: 255-261.
16. Katz A, Ekberg K, Johansson BL, Wahren J. Diminished skin blood flow in Type I diabetes: evidence for non-endothelium-dependent dysfunction. Clin Sci 2001; 101: 59-64.
17. Houben AJ, Schaper NC, Slaaf DW, Tangelder GJ, Nieuwenhuijzen Kruseman AC. Skin blood cell flux in insulin-dependent diabetic subjects in relation to retinopathy or incipient nephropathy. Eur J Clin Invest 1992; 22: 67-72.
18. Veves A, Akbari CM, Primavera J, et al. Endothelial dysfunction and the expression of endothelial nitric oxide synthetase in diabetic neuropathy, vascular disease, and foot ulceration. Diabetes 1998; 47: 457-463.
19. Greenman RL, Panasyuk S, Wang X, et al. Early changes in the skin microcirculation and muscle metabolism of the diabetic foot. Lancet 2005; 366: 1711-1717.
20. Suzuki E, Kashiwagi A, Hidaka H, et al. 1H- and 31P-magnetic resonance spectroscopy and imaging as a new diagnostic tool to evaluate neuropathic foot ulcers in Type II diabetic patients. Diabetologia 2000; 43: 165-172.
21. Flynn MD, Tooke JE. Diabetic neuropathy and the microcirculation. Diabet Med 1995; 12: 298-301.
22. Arora S, Pomposelli F, LoGerfo FW, Veves A. Cutaneous microcirculation in the neuropathic diabetic foot improves significantly but not completely after successful lower extremity revascularization. J Vasc Surg 2002; 35: 501-505.
23. Walmsley D, Wiles PG. Early loss of neurogenic inflammation in the human diabetic foot. Clin Sci 1991; 80: 605-610.
24. Pfutzner A, Forst T, Engelbach M, et al. The influence of isolated small nerve fibre dysfunction on microvascular control in patients with diabetes mellitus. Diabet Med 2001; 18: 489-494.
25. Kramer HH, Schmelz M, Birklein F, Bickel A. Electrically stimulated axon reflexes are diminished in diabetic small fiber neuropathies. Diabetes 2004; 53: 769-774.
26. Krishnan ST, Rayman G. The LDIflare: a novel test of C-fiber function demonstrates early neuropathy in type 2 diabetes. Diabetes Care 2004; 27: 2930-2935.
27. Koitka A, Abraham P, Bouhanick B, Sigaudo-Roussel D, Demiot C, Saumet JL. Impaired pressure-induced vasodilation at the foot in young adults with type 1 diabetes. Diabetes 2004; 53: 721-725.
28. Richards AM, Floyd DC, Terenghi G, McGrouther DA. Cellular changes in denervated tissue during wound healing in a rat model. Br J Dermatol 1999; 140: 1093-1099.
29. Smith PG, Liu M. Impaired cutaneous wound healing after sensory denervation in developing rats: effects on cell proliferation and apoptosis. Cell Tissue Res 2002; 307: 281-291.
30. Nabuurs-Franssen MH, Sleegers R, Huijberts MS, et al. Total contact casting of the diabetic foot in daily practice: a prospective follow-up study. Diabetes Care 2005; 28: 243-247.
31. Krishnan ST, Quattrini C, Jeziorska M, Malik RA, Rayman G. Neurovascular factors in wound healing in the foot skin of type 2 diabetic subjects. Diabetes Care 2007; 30: 3058-3062.
32. Tracey KJ. Physiology and immunology of the cholinergic and inflammatory pathway. J Clin Invest 2007; 117: 289-296.
33. Di Carli MF, Bianco-Battles D, Landa ME, et al. Effects of autonomic neuropathy on coronary blood flow in patients with diabetes mellitus. Circulation 1999; 100: 813-819.
34. Nitenberg A, Ledoux S, Valensi P, Sachs R, Attali JR, Antony I. Impairment of coronary microvascular dilation in response to cold pressor-induced sympathetic stimulation in type 2 diabetic patients with abnormal stress thallium imaging. Diabetes 2001; 50: 1180-1185.
35. Maser RE, Lenhard MJ. Cardiovascular autonomic neuropathy due to diabetes mellitus: clinical manifestations, consequences, and treatment. J Clin Endocrinol Metab 2005; 90: 5896-5903.
36. Scheuermann-Freestone M, Madsen PL, Manners D, et al. Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes. Circulation 2003; 107: 3040-3046.
37. Prompers L, Huijberts M, Apelqvist J, et al. High prevalence of ischaemia, infection and serious comorbidity in patients with diabetic foot disease in Europe. Baseline results from the Eurodiale study. Diabetologia 2007; 50: 18-25.
38. Lipsky BA, International consensus group on diagnosing and treating the infected diabetic foot. A report from the international consensus on diagnosing and treating the infected diabetic foot. Diabetes Metab Res Rev 2004; 20(Suppl. 1): S68-S77.
39. Beresford L, Orange O, Bell EB, Miyan JA. Nerve fibres are required to evoke a contact sensitivity response in mice. Immunology 2004; 111: 118-125.
40. Petrova NL, Moniz C, Elias DA, Buxton-Thomas M, Bates M, Edmonds ME. Is there a systemic inflammatory response in the acute charcot foot? Diabetes Care 2007; 30: 997-998.
41. Stevens MJ, Dayanikli F, Raffel DM, et al. Scintigraphic assessment of regionalized defects in myocardial sympathetic innervation and blood flow regulation in diabetic patients with autonomic neuropathy. J Am Coll Cardiol 1998; 31: 1575-1584.