Adaptation to hypoxia in the diabetic rat kidney

Kidney International

Volumn 73, Issue 1, 2008, Pages 34-42

  Rosenberger, C ^a   Khamaisi, M ^b,c   Abassi, Z ^d   Shilo, V ^b,c   Weksler Zangen, S ^b,c   Goldfarb, M ^e   Shina, A ^b,c   Zibertrest, F ^b,c   Eckardt, K U ^f   Rosen, S ^g   Heyman, S N ^b,c  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^c HEBREW UNIVERSITY   (Israel)

^d TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^e BIKUR CHOLIM HOSPITAL   (Israel)

^f UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^g HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Cell biology; Diabetes mellitus; Heme oxygenase; Hypoxia; Immunohistochemistry; Renal pathology

Indexed keywords

CONTRAST MEDIUM; GLUCOSE; HEME OXYGENASE 1; HYPOXIA INDUCIBLE FACTOR 1; OCTREOTIDE; PIMONIDAZOLE; STREPTOZOCIN; SUPEROXIDE DISMUTASE; TEMPOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISEASE ASSOCIATION; ENZYME INDUCTION; GLOMERULUS FILTRATION RATE; HYPERGLYCEMIA; HYPOXIA; INTRAVENOUS GLUCOSE TOLERANCE TEST; KIDNEY ISCHEMIA; MALE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT; STREPTOZOCIN DIABETES;

EID: 37249086816     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5002567     Document Type: Article

References (51)

1. Hochachka PW, Buck LT, Doll CJ, Land C. Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack. Proc Natl Acad Sci USA 1996; 93: 9493-9498.
2. Palm F, Cederberg J, Hansell P et al. Reactive oxygen species cause diabetes-induced decrease in renal oxygen tension. Diabetologia 2003; 46: 1153-1160.
3. Ries M, Basseau F, Tyndal B et al. Renal diffusion and BOLD MRI in experimental diabetic nephropathy. Blood oxygen level-dependent. J Magn Reson Imaging 2003; 17: 104-113.
4. Eckardt KU, Bernhardt WM, Weidemann A et al. Role of hypoxia in the pathogenesis of renal disease. Kidney Int Suppl 2005; 99: S46-S51.
5. Rosenberger C, Rosen S, Heyman SN. Intrarenal oxygenation in acute renal failure. Clin Exp Pharmacol Physiol 2006; 33: 980-988.
6. Nangaku M. Chronic hypoxia and tubulointerstitial injury: a final common pathway to end stage renal failure. J Am Soc Nephrol 2006; 17: 17-25.
7. Griffin MD, Bergstralhn EJ, Larson TS. Renal papillary necrosis - a sixteen-year clinical experience. J Am Soc Nephrol 1995; 6: 248-256.
8. Rudnick MR, Goldfarb S, Wexler L et al. Nephrotoxicity of ionic and nonionic contrast media in 1196 patients: a randomized trial. The lohexol Cooperative Study. Kidney Int 1995; 47: 254-261.
9. McCullough PA, Wolyn R, Rocher LL et al. Acute renal failure after coronary intervention: incidence, risk factors, and relationship to mortality. Am J Med 1997; 103: 368-375.
10. Thakar CV, Arrigain S, Worley S et al. A clinical score to predict acute renal failure after cardiac surgery. J Am Soc Nephrol 2005; 16: 162-168.
11. Rosner MH, Okusa MD. Acute kidney injury associated with cardiac surgery. Clin J Am Soc Nephrol 2006; 1: 19-32.
12. Jones CA, Krolewski AS, Rogus J et al. Epidemic of end-stage renal disease in people with diabetes in the United States population: do we know the cause? Kidney Int 2005; 67: 1684-1691.
13. Maxwell PH. HIF-1's relationship to oxygen: simple yet sophisticated. Cell Cycle 2004; 3: 156-159.
14. Metzen E, Ratcliffe PJ. HIF hydroxylation and cellular oxygen sensing. Biol Chem 2004; 385: 223-230.
15. Semenza GL. Hydroxylation of HIF-1: oxygen sensing at the molecular level. Physiology 2004; 19: 176-182.
16. Rosenberger C, Rosen S, Heyman S. Current understanding of HIF in renal disease. Kidney Blood Press Res 2005; 28: 325-340.
17. Arjamaa O, Nikinmaa M. Oxygen-dependent diseases in the retina: role of hypoxia-inducible factors. Exp Eye Res 2006; 83: 473-483.
18. Pouyssegur J, Mechta-Grigoriou F. Redox regulation of the hypoxia-inducible factor. Biol Chem 2006; 387: 1337-1346.
19. Kaelin Jr WG. ROS: really involved in oxygen sensing. Cell Metab 2005; 1: 357-358.
20. Kietzmann T, Gorlach A. Reactive oxygen species in the control of hypoxia-inducible factor-mediated gene expression. Semin Cell Dev Biol 2005; 16: 474-486.
21. Zou AP, Cowley Jr AW. Reactive oxygen species and molecular regulation of renal oxygenation. Acta Physiol Scand 2003; 179: 233-241.
22. Fridlyand LE, Philipson LH. Oxidative reactive species in cell injury: mechanisms in diabetes mellitus and therapeutic approaches. Ann N Y Acad Sci 2005; 1066: 136-151.
23. Li N, Yi FX, Spurrier JL et al. Production of superoxide through NADH oxidase in thick ascending limb of Henle's loop in rat kidney. Am J Physiol Renal Physiol 2002; 282: F1111-F1119.
24. Zou AP, Li N, Cowley Jr AW. Production and actions of superoxide in the renal medulla. Hypertension 2001; 37: 547-553.
25. Juncos R, Garvin JL. Superoxide enhances Na-K-2Cl cotransporter activity in the thick ascending limb. Am J Physiol Renal Physiol 2005; 288: F982-F987.
26. Yang ZZ, Zhang AY, Yi FX et al. Redox regulation of HIF-1alpha levels and HO-1 expression in renal medullary interstitial cells. Am J Physiol Renal Physiol 2003; 284: F1207-F1215.
27. Banday AA, Marwaha A, Tallam LS, Lokhandwala MF. Tempol reduces oxidative stress, improves insulin sensitivity, decreases renal dopamine D1 receptor hyperphosphorylation, and restores D1 receptor-G-protein coupling and function in obese Zucker rats. Diabetes 2005; 54: 2219-2226.
28. Abraham NG, Kappas A. Heme oxygenase and the cardiovascular-renal system. Free Radic Biol Med 2005; 39: 1-25.
29. Rosenberger C, Heyman SN, Rosen S et al. Upregulation of HIF in experimental acute renal failure: evidence for a protective transcriptional response to hypoxia. Kidney Int 2005; 67: 531-542.
30. Rosenberger C, Griethe W, Gruber G et al. Cellular responses to hypoxia after renal segmental infarction. Kidney Int 2003; 64: 874-886.
31. Rosenberger C, Rosen S, Shina A et al. Hypoxia inducible factors and tubular cell survival in isolated perfused kidneys. Kidney Int 2006; 70: 60-70.
32. Rosenberger C, Mandriota S, Jürgensen JS et al. Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys. J Am Soc Nephrol 2002; 13: 1721-1732.
33. Manotham K, Tanaka T, Ohse T et al. A biologic role of HIF-1 in the renal medulla. Kidney Int 2005; 67: 1428-1439.
34. Prasad PV, Priatna A, Spokes K, Epstein FH. Changes in intrarenal oxygenation as evaluated by BOLD MRI in a rat kidney model for radiocontrast nephropathy. J Magn Reson Imaging 2001; 13: 744-747.
35. Kraynak AR, Storer RD, Jensen RD et al. Extent and persistence of streptozotocin-induced DNA damage and cell proliferation in rat kidney as determined by in vivo alkaline elution and BrdUrd labeling assays. Toxicol Appl Pharmacol 1995; 35: 279-286.
36. Epstein FH, Silva P, Spokes K et al. Renal medullary Na-K-ATPase and hypoxic injury in perfused rat kidneys. Kidney Int 1989; 36: 768-772.
37. Ward DT, Yau SK, Mee AP et al. Functional, molecular, and biochemical characterization of streptozotocin-induced diabetes. J Am Soc Nephrol 2001; 12: 779-790.
38. Leyssac PP, Holstein-Rathlou N-H, Skott O. Renal blood flow, early distal sodium, and plasma renin concentrations during osmotic diuresis. Am J Physiol Regul Integr Comp Physiol 2000; 279: R1268-R1276.
39. Wald H, Scherzer P, Rasch R, Popovtzer MM. Renal tubular Na(+)-K(+)-ATPase in diabetes mellitus: relationship to metabolic abnormality. Am J Physiol 1993; 265: E96-E101.
40. Tsimaratos M, Coste TC, Djemli-Shipkolye A et al. Gamma-linolenic acid restores renal medullary thick ascending limb Na(+), K(+)-ATPase activity in diabetic rats. J Nutr 2001; 131: 3160-3165.
41. Haddad JJ, Harb HL. Cytokines and the regulation of the hypoxia-inducible factor (HIF)-1alpha. Int Immunopharmacol 2005; 5: 461-483.
42. Zhou J, Fandrey J, Schümann J et al. NO and TNF-alpha release from activated macrophages stabilize HIF-1alpha in resting tubular LLC-PK1 cells. Am J Physiol 2003; 284: C439-C446.
43. Katavetin P, Miyata T, Inagi R et al. High glucose blunts vascular endothelial growth factor response to hypoxia via the oxidative stress-regulated hypoxia-inducible factor/hypoxia-responsible element pathway. J Am Soc Nephrol 2006; 17: 1405-1413.
44. Yagil H, Barak A, Ben-Dor D et al. Nonproteinuric diabetes-associated nephropathy in the Cohen rat model of type 2 diabetes. Diabetes 2005; 54: 1487-1496.
45. Weksler-Zangen S, Yagil H, Zangen DH et al. The newly inbred cohen diabetic rat. A non-obese normolipidemic genetic model of diet-induced type 2 diabetes expressing sex differences. Diabetes 2001; 50: 2521-2529.
46. Li J, Chen YJ, Quilley J. Effect of tempol on renal cyclooxygenase expression and activity in experimental diabetes in the rat. J Pharmacol Exp Ther 2005; 314: 818-824.
47. Nassar T, Kadery B, Lotan H et al. Effects of the superoxide dismutase-mimetic compound tempol on endothelial dysfunction in streptozotocin-induced diabetic rats. Eur J Pharmacol 2002; 436: 111-118.
48. Lien EL, Garsky VM. Route of administration as a factor in the selectivity of hormone suppression of a somatostatin analogue in rats. Horm Metab Res 1981; 13: 675-678.
49. Goldfarb M, Rosenberger C, Abassi Z et al. Acute-on-chronic renal failure in the rat: functional compensation and hypoxia tolerance. Am J Nephrol 2006; 26: 22-33.
50. Franko AJ, Chapmann JD. Binding of 14C-misonidazole to hypoxic cells in V79 spheroids. Br J Cancer 1982; 45: 694-699.
51. Arteel GE, Thurmann RG, Raleigh JA. Reductive metabolism of the hypoxia marker pimonidazole is regulated by oxygen tension independent of the pyridine nucleotide redox state. Eur J Biochem 1998; 253: 743-750.