-
2
-
-
84901605375
-
Understanding how cystic fibrosis mutations disrupt CFTR function: From single molecules to animal models
-
Wang Y, Wrennall JA, Cai Z, et al. Understanding how cystic fibrosis mutations disrupt CFTR function: from single molecules to animal models. Int J Biochem Cell Biol 2014;52:47-57.
-
(2014)
Int J Biochem Cell Biol
, vol.52
, pp. 47-57
-
-
Wang, Y.1
Wrennall, J.A.2
Cai, Z.3
-
3
-
-
34047166052
-
Airway surface dehydration in cystic fibrosis: Pathogenesis and therapy
-
Boucher RC. Airway surface dehydration in cystic fibrosis: pathogenesis and therapy. Annu Rev Med 2007;58:157-170.
-
(2007)
Annu Rev Med
, vol.58
, pp. 157-170
-
-
Boucher, R.C.1
-
4
-
-
84890429584
-
Nasal potential difference measurements in diagnosis of cystic fibrosis: An international survey
-
Naehrlich L, et al. Nasal potential difference measurements in diagnosis of cystic fibrosis: an international survey. J Cyst Fibros 2014;13:24-28.
-
(2014)
J Cyst Fibros
, vol.13
, pp. 24-28
-
-
Naehrlich, L.1
-
5
-
-
20944434002
-
Potential difference measurements in the lower airway of children with and without cystic fibrosis
-
Davies JC, et al. Potential difference measurements in the lower airway of children with and without cystic fibrosis. Am J Respir Crit Care Med 2005;171:1015-1019.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 1015-1019
-
-
Davies, J.C.1
-
6
-
-
52949154301
-
Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs
-
Rogers CS, et al. Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs. Science 2008; 321:1837-1841.
-
(2008)
Science
, vol.321
, pp. 1837-1841
-
-
Rogers, C.S.1
-
7
-
-
78649915334
-
Loss of anion transport without increased sodium absorption characterizes newborn porcine cystic fibrosis airway epithelia
-
Chen JH, et al. Loss of anion transport without increased sodium absorption characterizes newborn porcine cystic fibrosis airway epithelia. Cell 2010;143:911-923.
-
(2010)
Cell
, vol.143
, pp. 911-923
-
-
Chen, J.H.1
-
8
-
-
84863476402
-
Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung
-
Pezzulo AA, et al. Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung. Nature 2012;487:109-113.
-
(2012)
Nature
, vol.487
, pp. 109-113
-
-
Pezzulo, A.A.1
-
9
-
-
0022485439
-
Lysosomal enzymes from polymorphonuclear leukocytes and proteinase inhibitors in patients with cystic fibrosis
-
Goldstein W, and Doring G. Lysosomal enzymes from polymorphonuclear leukocytes and proteinase inhibitors in patients with cystic fibrosis. Am Rev Respir Dis 1986;134:49-56.
-
(1986)
Am Rev Respir Dis
, vol.134
, pp. 49-56
-
-
Goldstein, W.1
Doring, G.2
-
10
-
-
0026681802
-
Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line
-
Nakamura H, Yoshimura K, McElvaney NG, et al. Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line. J Clin Invest 1992;89:1478-1484.
-
(1992)
J Clin Invest
, vol.89
, pp. 1478-1484
-
-
Nakamura, H.1
Yoshimura, K.2
McElvaney, N.G.3
-
11
-
-
35748973573
-
Cystic fibrosis transmembrane conductance regulator-independent phagosomal acidification in macrophages
-
Haggie PM, and Verkman AS. Cystic fibrosis transmembrane conductance regulator-independent phagosomal acidification in macrophages. J Biol Chem 2007;282:31422-31428.
-
(2007)
J Biol Chem
, vol.282
, pp. 31422-31428
-
-
Haggie, P.M.1
Verkman, A.S.2
-
12
-
-
33748146503
-
CFTR regulates phagosome acidification in macrophages and alters bactericidal activity
-
Di A, et al. CFTR regulates phagosome acidification in macrophages and alters bactericidal activity. Nat Cell Biol 2006;8:933-944.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 933-944
-
-
Di, A.1
-
13
-
-
80051554943
-
Lack of cystic fibrosis transmembrane conductance regulator in CD3+ lymphocytes leads to aberrant cytokine secretion and hyperinflammatory adaptive immune responses
-
Mueller C, et al. Lack of cystic fibrosis transmembrane conductance regulator in CD3+ lymphocytes leads to aberrant cytokine secretion and hyperinflammatory adaptive immune responses. Am J Respir Cell Mol Biol 2011;44:922-929.
-
(2011)
Am J Respir Cell Mol Biol
, vol.44
, pp. 922-929
-
-
Mueller, C.1
-
14
-
-
84929820981
-
-
last accessed May 11, 2015
-
Cystic Fibrosis Worldwide. www.cfww.org (last accessed May 11, 2015).
-
-
-
-
15
-
-
84929820982
-
-
last accessed April 28, 2015
-
Cystic Fibrosis Registry. www.cysticfibrosis.org.uk/media/598466/annual-data-report-2013-jul14.pdf (last accessed April 28, 2015).
-
-
-
-
16
-
-
0024423668
-
Identification of the cystic fibrosis gene: Genetic analysis
-
Kerem B, et al. Identification of the cystic fibrosis gene: genetic analysis. Science 1989;245:1073-1080.
-
(1989)
Science
, vol.245
, pp. 1073-1080
-
-
Kerem, B.1
-
17
-
-
0024424270
-
Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
-
Riordan JR, et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 1989;245:1066-1073.
-
(1989)
Science
, vol.245
, pp. 1066-1073
-
-
Riordan, J.R.1
-
18
-
-
0024453308
-
Identification of the cystic fibrosis gene: Chromosome walking and jumping
-
Rommens JM, et al. Identification of the cystic fibrosis gene: chromosome walking and jumping. Science 1989; 245:1059-1065.
-
(1989)
Science
, vol.245
, pp. 1059-1065
-
-
Rommens, J.M.1
-
19
-
-
0003452177
-
-
last accessed May 11, 2015
-
Cystic Fibrosis Mutation Database. www.genet.sickkids.on.ca/cftr/ (last accessed May 11, 2015).
-
Cystic Fibrosis Mutation Database
-
-
-
20
-
-
84929820983
-
-
last accessed May 11, 2015
-
Cystic Fibrosis Foundation. www.cff.org/research/TDN/ (last accessed May 11, 2015).
-
-
-
-
21
-
-
84929820984
-
-
last accessed May 11, 2015
-
European Cystic Fibrosis Society https://www.ecfs.eu/ctn (last accessed May 11, 2015).
-
-
-
-
22
-
-
80455162465
-
A CFTR potentiator in patients with cystic fibrosis and the G551D mutation
-
Ramsey BW, et al. A CFTR potentiator in patients with cystic fibrosis and the G551D mutation. N Engl J Med 2011;365:1663-1672.
-
(2011)
N Engl J Med
, vol.365
, pp. 1663-1672
-
-
Ramsey, B.W.1
-
23
-
-
84911493956
-
Efficacy and safety of ivacaftor in patients with cystic fibrosis and a non-G551D gating mutation
-
De Boeck K, et al. Efficacy and safety of ivacaftor in patients with cystic fibrosis and a non-G551D gating mutation. J Cyst Fibros 2014;13:674-680.
-
(2014)
J Cyst Fibros
, vol.13
, pp. 674-680
-
-
De Boeck, K.1
-
24
-
-
84918819788
-
New pharmacological approaches for cystic fibrosis: Promises, progress, pitfalls
-
Bell SC, De BK, and Amaral MD. New pharmacological approaches for cystic fibrosis: promises, progress, pitfalls. Pharmacol Ther 2015;145C:19-34.
-
(2015)
Pharmacol Ther
, vol.145 C
, pp. 19-34
-
-
Bell, S.C.1
De, B.K.2
Amaral, M.D.3
-
25
-
-
84861891585
-
Advances in cell and gene-based therapies for cystic fibrosis lung disease
-
Oakland M, Sinn PL, and McCray PB, Jr. Advances in cell and gene-based therapies for cystic fibrosis lung disease. Mol Ther 2012;20:1108-1115.
-
(2012)
Mol Ther
, vol.20
, pp. 1108-1115
-
-
Oakland, M.1
Sinn, P.L.2
McCray, P.B.3
-
26
-
-
0026918861
-
Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis
-
Johnson LG, et al. Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis. Nat Genet 1992;2:21-25.
-
(1992)
Nat Genet
, vol.2
, pp. 21-25
-
-
Johnson, L.G.1
-
27
-
-
68049143467
-
CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium
-
Zhang L, et al. CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium. PLoS Biol 2009;7:e1000155.
-
(2009)
PLoS Biol
, vol.7
, pp. e1000155
-
-
Zhang, L.1
-
28
-
-
84877079632
-
Adenoviral gene transfer corrects the ion transport defect in the sinus epithelia of a porcine CF model
-
Potash AE, et al. Adenoviral gene transfer corrects the ion transport defect in the sinus epithelia of a porcine CF model. Mol Ther 2013;21:947-953.
-
(2013)
Mol Ther
, vol.21
, pp. 947-953
-
-
Potash, A.E.1
-
29
-
-
0027502580
-
Genetic basis of variable exon 9 skipping in cystic fibrosis transmembrane conductance regulator mRNA
-
Chu CS, Trapnell BC, Curristin S, et al. Genetic basis of variable exon 9 skipping in cystic fibrosis transmembrane conductance regulator mRNA. Nat Genet 1993;3:151-156.
-
(1993)
Nat Genet
, vol.3
, pp. 151-156
-
-
Chu, C.S.1
Trapnell, B.C.2
Curristin, S.3
-
30
-
-
0033586375
-
Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: A double-blind placebo-controlled trial
-
Alton EW, et al. Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: a double-blind placebo-controlled trial. Lancet 1999;353:947-954.
-
(1999)
Lancet
, vol.353
, pp. 947-954
-
-
Alton, E.W.1
-
31
-
-
0033924663
-
Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis
-
Hyde SC, et al. Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis. Gene Ther 2000;7:1156-1165.
-
(2000)
Gene Ther
, vol.7
, pp. 1156-1165
-
-
Hyde, S.C.1
-
32
-
-
0028912888
-
Normalization of raised sodium absorption and raised calcium-mediated chloride secretion by adenovirus-mediated expression of cystic fibrosis transmembrane conductance regulator in primary human cystic fibrosis airway epithelial cells
-
Johnson LG, Boyles SE, Wilson J, et al. Normalization of raised sodium absorption and raised calcium-mediated chloride secretion by adenovirus-mediated expression of cystic fibrosis transmembrane conductance regulator in primary human cystic fibrosis airway epithelial cells. J Clin Invest 1995;95:1377-1382.
-
(1995)
J Clin Invest
, vol.95
, pp. 1377-1382
-
-
Johnson, L.G.1
Boyles, S.E.2
Wilson, J.3
-
33
-
-
27944491619
-
Gene transfer of CFTR to airway epithelia: Low levels of expression are sufficient to correct Cl - Transport and overexpression can generate basolateral CFTR
-
Farmen SL, et al. Gene transfer of CFTR to airway epithelia: low levels of expression are sufficient to correct Cl - transport and overexpression can generate basolateral CFTR. Am J Physiol Lung Cell Mol Physiol 2005;289: L1123-L1130.
-
(2005)
Am J Physiol Lung Cell Mol Physiol
, vol.289
, pp. L1123-L1130
-
-
Farmen, S.L.1
-
34
-
-
78649647597
-
Role of epithelial HCO3 transport in mucin secretion: Lessons from cystic fibrosis
-
Quinton PM. Role of epithelial HCO3 transport in mucin secretion: lessons from cystic fibrosis. Am J Physiol Cell Physiol 2010;299:C1222-C1233.
-
(2010)
Am J Physiol Cell Physiol
, vol.299
, pp. C1222-C1233
-
-
Quinton, P.M.1
-
35
-
-
0026951303
-
Submucosal glands are the predominant site of CFTR expression in the human bronchus
-
Engelhardt JF, et al. Submucosal glands are the predominant site of CFTR expression in the human bronchus. Nat Genet 1992;2:240-248.
-
(1992)
Nat Genet
, vol.2
, pp. 240-248
-
-
Engelhardt, J.F.1
-
36
-
-
18244377969
-
Characterization of wild-type and DF508 cystic fibrosis transmembrane regulator in human respiratory epithelia
-
Kreda SM, et al. Characterization of wild-type and DF508 cystic fibrosis transmembrane regulator in human respiratory epithelia. Mol Biol Cell 2005;16:2154-2167.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 2154-2167
-
-
Kreda, S.M.1
-
37
-
-
0033918281
-
Cystic fibrosis F508del patients have apically localized CFTR in a reduced number of airway cells
-
Penque D, et al. Cystic fibrosis F508del patients have apically localized CFTR in a reduced number of airway cells. Lab Invest 2000;80:857-868.
-
(2000)
Lab Invest
, vol.80
, pp. 857-868
-
-
Penque, D.1
-
38
-
-
72149093771
-
Disease-causing mutations in the cystic fibrosis transmembrane conductance regulator determine the functional responses of alveolar macrophages
-
Deriy LV, et al. Disease-causing mutations in the cystic fibrosis transmembrane conductance regulator determine the functional responses of alveolar macrophages. J Biol Chem 2009;284:35926-35938.
-
(2009)
J Biol Chem
, vol.284
, pp. 35926-35938
-
-
Deriy, L.V.1
-
39
-
-
33748654201
-
CFTR Expression in human neutrophils and the phagolysosomal chlorination defect in cystic fibrosis
-
Painter RG, et al. CFTR Expression in human neutrophils and the phagolysosomal chlorination defect in cystic fibrosis. Biochemistry 2006;45:10260-10269.
-
(2006)
Biochemistry
, vol.45
, pp. 10260-10269
-
-
Painter, R.G.1
-
40
-
-
84884802285
-
Moving forward: Cystic fibrosis gene therapy
-
Griesenbach U, and Alton EW. Moving forward: cystic fibrosis gene therapy. Hum Mol Genet 2013;22:R52-R58.
-
(2013)
Hum Mol Genet
, vol.22
, pp. R52-R58
-
-
Griesenbach, U.1
Alton, E.W.2
-
41
-
-
4644258829
-
Adenoviral vectors for gene transfer and therapy
-
Volpers C, and Kochanek S. Adenoviral vectors for gene transfer and therapy. J Gene Med 2004;6 Suppl 1:S164-S171.
-
(2004)
J Gene Med
, vol.6
, pp. S164-S171
-
-
Volpers, C.1
Kochanek, S.2
-
42
-
-
33845411897
-
Visualization of a-helices in a 6-Ångstrom resolution cryoelectron microscopy structure of adenovirus allows refinement of capsid protein assignments
-
Saban SD, Silvestry M, Nemerow GR, et al. Visualization of a-helices in a 6-Ångstrom resolution cryoelectron microscopy structure of adenovirus allows refinement of capsid protein assignments. J Virol 2006;80:12049-12059.
-
(2006)
J Virol
, vol.80
, pp. 12049-12059
-
-
Saban, S.D.1
Silvestry, M.2
Nemerow, G.R.3
-
43
-
-
59849102099
-
Adenoviruses: Update on structure and function
-
Russell WC. Adenoviruses: update on structure and function. J Gen Virol 2009;90:1-20.
-
(2009)
J Gen Virol
, vol.90
, pp. 1-20
-
-
Russell, W.C.1
-
44
-
-
43049178300
-
Progress and prospects: Gene therapy for genetic diseases with helper-dependent adenoviral vectors
-
Brunetti-Pierri N, and Ng P. Progress and prospects: gene therapy for genetic diseases with helper-dependent adenoviral vectors. Gene Ther 2008;15:553-560.
-
(2008)
Gene Ther
, vol.15
, pp. 553-560
-
-
Brunetti-Pierri, N.1
Ng, P.2
-
45
-
-
0027377523
-
Adenovirusmediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis
-
Zabner J, Couture LA, Gregory RJ, et al. Adenovirusmediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis. Cell 1993;75:207-216.
-
(1993)
Cell
, vol.75
, pp. 207-216
-
-
Zabner, J.1
Couture, L.A.2
Gregory, R.J.3
-
46
-
-
0028168641
-
Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis
-
Crystal RG, et al. Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis. Nat Genet 1994;8:42-51.
-
(1994)
Nat Genet
, vol.8
, pp. 42-51
-
-
Crystal, R.G.1
-
47
-
-
0029100239
-
A controlled study of adenoviral-vectormediated gene transfer in the nasal epithelium of patients with cystic fibrosis
-
Knowles MR, et al. A controlled study of adenoviral-vectormediated gene transfer in the nasal epithelium of patients with cystic fibrosis. N Engl J Med 1995;333:823-831.
-
(1995)
N Engl J Med
, vol.333
, pp. 823-831
-
-
Knowles, M.R.1
-
48
-
-
0028802876
-
Modification of nasal epithelial potential differences of individuals with cystic fibrosis consequent to local administration of a normal CFTR cDNA adenovirus gene transfer vector
-
Hay JG, McElvaney NG, Herena J, et al. Modification of nasal epithelial potential differences of individuals with cystic fibrosis consequent to local administration of a normal CFTR cDNA adenovirus gene transfer vector. Hum Gene Ther 1995;6:1487-1496.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1487-1496
-
-
Hay, J.G.1
McElvaney, N.G.2
Herena, J.3
-
49
-
-
13344286312
-
Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis
-
Zabner J, et al. Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis. J Clin Invest 1996;97:1504-1511.
-
(1996)
J Clin Invest
, vol.97
, pp. 1504-1511
-
-
Zabner, J.1
-
50
-
-
16944367323
-
Aerosol administration of a recombinant adenovirus expressing CFTR to cystic fibrosis patients: A phase I clinical trial
-
Bellon G, et al. Aerosol administration of a recombinant adenovirus expressing CFTR to cystic fibrosis patients: a phase I clinical trial. Hum Gene Ther 1997;8:15-25.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 15-25
-
-
Bellon, G.1
-
51
-
-
0032718592
-
Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus
-
Harvey BG, et al. Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus. J Clin Invest 1999; 104:1245-1255.
-
(1999)
J Clin Invest
, vol.104
, pp. 1245-1255
-
-
Harvey, B.G.1
-
52
-
-
0033544951
-
A phase I study of adenovirusmediated transfer of the human cystic fibrosis transmembrane conductance regulator gene to a lung segment of individuals with cystic fibrosis
-
Zuckerman JB, et al. A phase I study of adenovirusmediated transfer of the human cystic fibrosis transmembrane conductance regulator gene to a lung segment of individuals with cystic fibrosis. Hum Gene Ther 1999;10:2973-2985.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 2973-2985
-
-
Zuckerman, J.B.1
-
53
-
-
0034820241
-
Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. I. Methods, safety, and clinical implications
-
Joseph PM, et al. Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. I. Methods, safety, and clinical implications. Hum Gene Ther 2001;12:1369-1382.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 1369-1382
-
-
Joseph, P.M.1
-
54
-
-
0034831612
-
Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. II. Transfection efficiency in airway epithelium
-
Perricone MA, et al. Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. II. Transfection efficiency in airway epithelium. Hum Gene Ther 2001;12:1383-1394.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 1383-1394
-
-
Perricone, M.A.1
-
55
-
-
0033537837
-
Basolateral localization of fiber receptors limits adenovirus infection from the apical surface of airway epithelia
-
Walters RW, et al. Basolateral localization of fiber receptors limits adenovirus infection from the apical surface of airway epithelia. J Biol Chem 1999;274:10219-10226.
-
(1999)
J Biol Chem
, vol.274
, pp. 10219-10226
-
-
Walters, R.W.1
-
56
-
-
27944457244
-
Aerosol delivery of an enhanced helperdependent adenovirus formulation to rabbit lung using an intratracheal catheter
-
Koehler DR, et al. Aerosol delivery of an enhanced helperdependent adenovirus formulation to rabbit lung using an intratracheal catheter. J Gene Med 2005;7:1409-1420.
-
(2005)
J Gene Med
, vol.7
, pp. 1409-1420
-
-
Koehler, D.R.1
-
57
-
-
79952143411
-
Gene therapy with helper-dependent adenoviral vectors: Current advances and future perspectives
-
Vetrini F, and Ng P. Gene therapy with helper-dependent adenoviral vectors: current advances and future perspectives. Viruses 2010;2:1886-1917.
-
(2010)
Viruses
, vol.2
, pp. 1886-1917
-
-
Vetrini, F.1
Ng, P.2
-
58
-
-
0037853137
-
Reduced inflammation and improved airway expression using helper-dependent adenoviral vectors with a K18 promoter
-
Toietta G, et al. Reduced inflammation and improved airway expression using helper-dependent adenoviral vectors with a K18 promoter. Mol Ther 2003;7:649-658.
-
(2003)
Mol Ther
, vol.7
, pp. 649-658
-
-
Toietta, G.1
-
59
-
-
0347364650
-
Protection of Cftr knockout mice from acute lung infection by a helper-dependent adenoviral vector expressing Cftr in airway epithelia
-
Koehler DR, et al. Protection of Cftr knockout mice from acute lung infection by a helper-dependent adenoviral vector expressing Cftr in airway epithelia. Proc Natl Acad Sci U S A 2003;100:15364-15369.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15364-15369
-
-
Koehler, D.R.1
-
60
-
-
84896730363
-
Differential adeno-associated virus serotype-specific interaction patterns with synthetic heparins and other glycans
-
Mietzsch M, Broecker F, Reinhardt A, et al. Differential adeno-associated virus serotype-specific interaction patterns with synthetic heparins and other glycans. J Virol 2014;88:2991-3003.
-
(2014)
J Virol
, vol.88
, pp. 2991-3003
-
-
Mietzsch, M.1
Broecker, F.2
Reinhardt, A.3
-
61
-
-
84861998784
-
Intracellular transport of recombinant adeno-associated virus vectors
-
Nonnenmacher M, and Weber T. Intracellular transport of recombinant adeno-associated virus vectors. Gene Ther 2012;19:649-658.
-
(2012)
Gene Ther
, vol.19
, pp. 649-658
-
-
Nonnenmacher, M.1
Weber, T.2
-
62
-
-
49149113894
-
Adeno-associated virus vector genomes persist as episomal chromatin in primate muscle
-
Penaud-Budloo M, et al. Adeno-associated virus vector genomes persist as episomal chromatin in primate muscle. J Virol 2008;82:7875-7885.
-
(2008)
J Virol
, vol.82
, pp. 7875-7885
-
-
Penaud-Budloo, M.1
-
63
-
-
0028534879
-
Adeno-associated virus vector gene expression occurs in nondividing cells in the absence of vector DNA integration
-
Flotte TR, Afione SA, and Zeitlin PL. Adeno-associated virus vector gene expression occurs in nondividing cells in the absence of vector DNA integration. Am J Respir Cell Mol Biol 1994;11:517-521.
-
(1994)
Am J Respir Cell Mol Biol
, vol.11
, pp. 517-521
-
-
Flotte, T.R.1
Afione, S.A.2
Zeitlin, P.L.3
-
64
-
-
84880289352
-
A largely random AAV integration profile after LPLD gene therapy
-
Kaeppel C, et al. A largely random AAV integration profile after LPLD gene therapy. Nat Med 2013;19:889-891.
-
(2013)
Nat Med
, vol.19
, pp. 889-891
-
-
Kaeppel, C.1
-
65
-
-
34548512049
-
Repeated aerosolized AAV-CFTR for treatment of cystic fibrosis: A randomized placebo-controlled phase 2B trial
-
Moss RB, et al. Repeated aerosolized AAV-CFTR for treatment of cystic fibrosis: a randomized placebo-controlled phase 2B trial. Hum Gene Ther 2007;18:726-732.
-
(2007)
Hum Gene Ther
, vol.18
, pp. 726-732
-
-
Moss, R.B.1
-
66
-
-
0027412209
-
Expression of the cystic fibrosis transmembrane conductance regulator from a novel adeno-associated virus promoter
-
Flotte TR, et al. Expression of the cystic fibrosis transmembrane conductance regulator from a novel adeno-associated virus promoter. J Biol Chem 1993;268:3781-3790.
-
(1993)
J Biol Chem
, vol.268
, pp. 3781-3790
-
-
Flotte, T.R.1
-
67
-
-
63649130139
-
Analysis of adeno-associated virus progenitor cell transduction in mouse lung
-
Liu X, et al. Analysis of adeno-associated virus progenitor cell transduction in mouse lung. Mol Ther 2009;17:285-293.
-
(2009)
Mol Ther
, vol.17
, pp. 285-293
-
-
Liu, X.1
-
68
-
-
84879683527
-
CpG-depleted adeno-associated virus vectors evade immune detection
-
Faust SM, et al. CpG-depleted adeno-associated virus vectors evade immune detection. J Clin Invest 2013;123: 2994-3001.
-
(2013)
J Clin Invest
, vol.123
, pp. 2994-3001
-
-
Faust, S.M.1
-
69
-
-
73849120718
-
Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints
-
Vandenberghe LH, et al. Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints. Gene Ther 2009;16:1416-1428.
-
(2009)
Gene Ther
, vol.16
, pp. 1416-1428
-
-
Vandenberghe, L.H.1
-
70
-
-
73849130017
-
Generation of novel AAV variants by directed evolution for improved CFTR delivery to human ciliated airway epithelium
-
Li W, et al. Generation of novel AAV variants by directed evolution for improved CFTR delivery to human ciliated airway epithelium. Mol Ther 2009;17:2067-2077.
-
(2009)
Mol Ther
, vol.17
, pp. 2067-2077
-
-
Li, W.1
-
71
-
-
77649272865
-
Dual reporter comparative indexing of rAAV pseudotyped vectors in chimpanzee airway
-
Flotte TR, et al. Dual reporter comparative indexing of rAAV pseudotyped vectors in chimpanzee airway. Mol Ther 2010;18:594-600.
-
(2010)
Mol Ther
, vol.18
, pp. 594-600
-
-
Flotte, T.R.1
-
72
-
-
77953128609
-
Expression of human a1 -antitrypsin in mice and dogs following AAV6 vector-mediated gene transfer to the lungs
-
Halbert CL, et al. Expression of human a1 -antitrypsin in mice and dogs following AAV6 vector-mediated gene transfer to the lungs. Mol Ther 2010;18:1165-1172.
-
(2010)
Mol Ther
, vol.18
, pp. 1165-1172
-
-
Halbert, C.L.1
-
73
-
-
62549150024
-
Transduction efficiencies of novel AAV vectors in mouse airway epithelium in vivo and human ciliated airway epithelium in vitro
-
Limberis MP, Vandenberghe LH, Zhang L, et al. Transduction efficiencies of novel AAV vectors in mouse airway epithelium in vivo and human ciliated airway epithelium in vitro. Mol Ther 2009;17:294-301.
-
(2009)
Mol Ther
, vol.17
, pp. 294-301
-
-
Limberis, M.P.1
Vandenberghe, L.H.2
Zhang, L.3
-
74
-
-
84859440283
-
The AAV vector toolkit: Poised at the clinical crossroads
-
Asokan A, Schaffer DV, and Samulski RJ. The AAV vector toolkit: poised at the clinical crossroads. Mol Ther 2012;20:699-708.
-
(2012)
Mol Ther
, vol.20
, pp. 699-708
-
-
Asokan, A.1
Schaffer, D.V.2
Samulski, R.J.3
-
75
-
-
43049119982
-
Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice
-
Allocca M, et al. Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice. J Clin Invest 2008;118:1955-1964.
-
(2008)
J Clin Invest
, vol.118
, pp. 1955-1964
-
-
Allocca, M.1
-
76
-
-
62549141507
-
Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental transsplicing
-
Song Y, et al. Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental transsplicing. Hum Gene Ther 2009;20:267-281.
-
(2009)
Hum Gene Ther
, vol.20
, pp. 267-281
-
-
Song, Y.1
-
77
-
-
84890129810
-
A novel chimeric adenoassociated virus 2/ human bocavirus 1 parvovirus vector efficiently transduces human airway epithelia
-
Yan Z, et al. A novel chimeric adenoassociated virus 2/ human bocavirus 1 parvovirus vector efficiently transduces human airway epithelia. Mol Ther 2013;21:2181-2194.
-
(2013)
Mol Ther
, vol.21
, pp. 2181-2194
-
-
Yan, Z.1
-
78
-
-
84905442242
-
Overcoming the cystic fibrosis sputum barrier to leading adeno-associated virus gene therapy vectors
-
Schuster BS, et al. Overcoming the cystic fibrosis sputum barrier to leading adeno-associated virus gene therapy vectors. Mol Ther 2014;22:1484-1493.
-
(2014)
Mol Ther
, vol.22
, pp. 1484-1493
-
-
Schuster, B.S.1
-
79
-
-
84910633195
-
In vivo evaluation of adeno-associated virus gene transfer in airways of mice with acute or chronic respiratory infection
-
Myint M, et al. In vivo evaluation of adeno-associated virus gene transfer in airways of mice with acute or chronic respiratory infection. Hum Gene Ther 2014;25:966-976.
-
(2014)
Hum Gene Ther
, vol.25
, pp. 966-976
-
-
Myint, M.1
-
80
-
-
84911383748
-
Long-term safety and efficacy of factor IX gene therapy in hemophilia B
-
Nathwani AC, et al. Long-term safety and efficacy of factor IX gene therapy in hemophilia B. N Engl J Med 2014;371:1994-2004.
-
(2014)
N Engl J Med
, vol.371
, pp. 1994-2004
-
-
Nathwani, A.C.1
-
81
-
-
84928599756
-
The status of RPE65 gene therapy trials: Safety and efficacy
-
Epub ahead of print
-
Pierce EA, and Bennett J. The status of RPE65 gene therapy trials: safety and efficacy. Cold Spring Harb Perspect Med 2015 [Epub ahead of print]; DOI: 10.1101/cshperspect.a017285.
-
(2015)
Cold Spring Harb Perspect Med
-
-
Pierce, E.A.1
Bennett, J.2
-
82
-
-
84929820985
-
-
last accessed May 11, 2015
-
Pfizer. www.pfizer.com/news (last accessed May 11, 2015).
-
-
-
-
83
-
-
84929820986
-
-
last accessed May 11, 2015
-
Sanofi-Genzyme. http://news.genzyme.com/ (last accessed May 11, 2015).
-
-
-
-
84
-
-
78650141161
-
a-Fetoprotein gene delivery to the nasal epithelium of nonhuman primates by human parainfluenza viral vectors
-
Zhang L, et al. a-Fetoprotein gene delivery to the nasal epithelium of nonhuman primates by human parainfluenza viral vectors. Hum Gene Ther 2010;21:1657-1664.
-
(2010)
Hum Gene Ther
, vol.21
, pp. 1657-1664
-
-
Zhang, L.1
-
86
-
-
34548730279
-
Sendai virus-mediated CFTR gene transfer to the airway epithelium
-
Ferrari S, et al. Sendai virus-mediated CFTR gene transfer to the airway epithelium. Gene Ther 2007;14:1371-1379.
-
(2007)
Gene Ther
, vol.14
, pp. 1371-1379
-
-
Ferrari, S.1
-
87
-
-
79951517862
-
Validation of recombinant Sendai virus in a non-natural host model
-
Griesenbach U, et al. Validation of recombinant Sendai virus in a non-natural host model. Gene Ther 2010;18: 182-188.
-
(2010)
Gene Ther
, vol.18
, pp. 182-188
-
-
Griesenbach, U.1
-
88
-
-
33645139296
-
Effect of tolerance induction to immunodominant T-cell epitopes of Sendai virus on gene expression following repeat administration to lung
-
Griesenbach U, et al. Effect of tolerance induction to immunodominant T-cell epitopes of Sendai virus on gene expression following repeat administration to lung. Gene Ther 2006;13:449-456.
-
(2006)
Gene Ther
, vol.13
, pp. 449-456
-
-
Griesenbach, U.1
-
89
-
-
84879867061
-
Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome
-
Aiuti A, et al. Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome. Science 2013;341:1233151.
-
(2013)
Science
, vol.341
, pp. 1233151
-
-
Aiuti, A.1
-
90
-
-
84879873039
-
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy
-
Biffi A, et al. Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy. Science 2013;341:1233158.
-
(2013)
Science
, vol.341
, pp. 1233158
-
-
Biffi, A.1
-
91
-
-
84897076939
-
Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: A dose escalation, open-label, phase 1/2 trial
-
Palfi S, et al. Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial. Lancet 2014;383:1138-1146.
-
(2014)
Lancet
, vol.383
, pp. 1138-1146
-
-
Palfi, S.1
-
92
-
-
84878941170
-
New developments in lentiviral vector design, production and purification
-
Segura MM, Mangion M, Gaillet B, et al. New developments in lentiviral vector design, production and purification. Expert Opin Biol Ther 2013;13:987-1011.
-
(2013)
Expert Opin Biol Ther
, vol.13
, pp. 987-1011
-
-
Segura, M.M.1
Mangion, M.2
Gaillet, B.3
-
93
-
-
0036431592
-
Recovery of airway cystic fibrosis transmembrane conductance regulator function in mice with cystic fibrosis after single-dose lentivirus-mediated gene transfer
-
Limberis M, Anson DS, Fuller M, et al. Recovery of airway cystic fibrosis transmembrane conductance regulator function in mice with cystic fibrosis after single-dose lentivirus-mediated gene transfer. Hum Gene Ther 2002; 13:1961-1970.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1961-1970
-
-
Limberis, M.1
Anson, D.S.2
Fuller, M.3
-
94
-
-
0037320020
-
Pseudotyped lentivirus vectors derived from simian immunodeficiency virus SIVagm with envelope glycoproteins from paramyxovirus
-
Kobayashi M, Iida A, Ueda Y, et al. Pseudotyped lentivirus vectors derived from simian immunodeficiency virus SIVagm with envelope glycoproteins from paramyxovirus. J Virol 2003;77:2607-2614.
-
(2003)
J Virol
, vol.77
, pp. 2607-2614
-
-
Kobayashi, M.1
Iida, A.2
Ueda, Y.3
-
95
-
-
55249121439
-
Lentivirus vector can be readministered to nasal epithelia without blocking immune responses
-
Sinn PL, Arias AC, Brogden KA, et al. Lentivirus vector can be readministered to nasal epithelia without blocking immune responses. J Virol 2008;82:10684-10692.
-
(2008)
J Virol
, vol.82
, pp. 10684-10692
-
-
Sinn, P.L.1
Arias, A.C.2
Brogden, K.A.3
-
96
-
-
84873046676
-
High efficiency gene transfer to airways of mice using influenza hemagglutinin pseudotyped lentiviral vectors
-
Patel M, Giddings AM, Sechelski J, et al. High efficiency gene transfer to airways of mice using influenza hemagglutinin pseudotyped lentiviral vectors. J Gene Med 2013;15:51-62.
-
(2013)
J Gene Med
, vol.15
, pp. 51-62
-
-
Patel, M.1
Giddings, A.M.2
Sechelski, J.3
-
97
-
-
77956667210
-
Lysophosphatidylcholine as an adjuvant for lentiviral vector mediated gene transfer to airway epithelium: Effect of acyl chain length
-
Cmielewski P, Anson DS, and Parsons DW. Lysophosphatidylcholine as an adjuvant for lentiviral vector mediated gene transfer to airway epithelium: effect of acyl chain length. Respir Res 2010;11:84.
-
(2010)
Respir Res
, vol.11
, pp. 84
-
-
Cmielewski, P.1
Anson, D.S.2
Parsons, D.W.3
-
98
-
-
18244409874
-
Viscoelastic gel formulations enhance airway epithelial gene transfer with viral vectors
-
Sinn PL, Shah AJ, Donovan MD, et al. Viscoelastic gel formulations enhance airway epithelial gene transfer with viral vectors. Am J Respir Cell Mol Biol 2005;32:404-410.
-
(2005)
Am J Respir Cell Mol Biol
, vol.32
, pp. 404-410
-
-
Sinn, P.L.1
Shah, A.J.2
Donovan, M.D.3
-
99
-
-
77953138185
-
Toward gene therapy for cystic fibrosis using a lentivirus pseudotyped with sendai virus envelopes
-
Mitomo K, et al. Toward gene therapy for cystic fibrosis using a lentivirus pseudotyped with sendai virus envelopes. Mol Ther 2010;18:1173-1182.
-
(2010)
Mol Ther
, vol.18
, pp. 1173-1182
-
-
Mitomo, K.1
-
100
-
-
84868266593
-
Assessment of F/HN-pseudotyped lentivirus as a clinically relevant vector for lung gene therapy
-
Griesenbach U, et al. Assessment of F/HN-pseudotyped lentivirus as a clinically relevant vector for lung gene therapy. Am J Respir Crit Care Med 2012;186:846-856.
-
(2012)
Am J Respir Crit Care Med
, vol.186
, pp. 846-856
-
-
Griesenbach, U.1
-
102
-
-
84886648166
-
The Committee for Advanced Therapies of the European Medicines Agency reflection paper on management of clinical risks deriving from insertional mutagenesis
-
Aiuti A, et al. The Committee for Advanced Therapies of the European Medicines Agency reflection paper on management of clinical risks deriving from insertional mutagenesis. Hum Gene Ther Clin Dev 2013;24:47-54.
-
(2013)
Hum Gene Ther Clin Dev
, vol.24
, pp. 47-54
-
-
Aiuti, A.1
-
103
-
-
77956928344
-
Transfusion independence and HMGA2 activation after gene therapy of human b-thalassaemia
-
Cavazzana-Calvo M, et al. Transfusion independence and HMGA2 activation after gene therapy of human b-thalassaemia. Nature 2010;467:318-322.
-
(2010)
Nature
, vol.467
, pp. 318-322
-
-
Cavazzana-Calvo, M.1
-
104
-
-
0028913411
-
Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
-
Caplen NJ, et al. Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Nat Med 1995;1:39-46.
-
(1995)
Nat Med
, vol.1
, pp. 39-46
-
-
Caplen, N.J.1
-
105
-
-
8244238394
-
A placebo-controlled study of liposomemediated gene transfer to the nasal epithelium of patients with cystic fibrosis
-
Gill DR, et al. A placebo-controlled study of liposomemediated gene transfer to the nasal epithelium of patients with cystic fibrosis. Gene Ther 1997;4:199-209.
-
(1997)
Gene Ther
, vol.4
, pp. 199-209
-
-
Gill, D.R.1
-
106
-
-
8244245761
-
Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
-
Porteous DJ, et al. Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Gene Ther 1997;4:210-218.
-
(1997)
Gene Ther
, vol.4
, pp. 210-218
-
-
Porteous, D.J.1
-
107
-
-
0033660570
-
Safety and biological efficacy of a lipid- CFTR complex for gene transfer in the nasal epithelium of adult patients with cystic fibrosis
-
Noone PG, et al. Safety and biological efficacy of a lipid- CFTR complex for gene transfer in the nasal epithelium of adult patients with cystic fibrosis. Mol Ther 2000;1:105-114.
-
(2000)
Mol Ther
, vol.1
, pp. 105-114
-
-
Noone, P.G.1
-
108
-
-
0034915570
-
A clinical inflammatory syndrome attributable to aerosolized lipid-DNA administration in cystic fibrosis
-
Ruiz FE, et al. A clinical inflammatory syndrome attributable to aerosolized lipid-DNA administration in cystic fibrosis. Hum Gene Ther 2001;12:751-761.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 751-761
-
-
Ruiz, F.E.1
-
109
-
-
0030759153
-
Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo
-
Zabner J, et al. Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo. J Clin Invest 1997;100:1529-1537.
-
(1997)
J Clin Invest
, vol.100
, pp. 1529-1537
-
-
Zabner, J.1
-
110
-
-
19944398726
-
Compacted DNA nanoparticles administered to the nasal mucosa of cystic fibrosis subjects are safe and demonstrate partial to complete cystic fibrosis transmembrane regulator reconstitution
-
Konstan MW, et al. Compacted DNA nanoparticles administered to the nasal mucosa of cystic fibrosis subjects are safe and demonstrate partial to complete cystic fibrosis transmembrane regulator reconstitution. Hum Gene Ther 2004;15:1255-1269.
-
(2004)
Hum Gene Ther
, vol.15
, pp. 1255-1269
-
-
Konstan, M.W.1
-
111
-
-
84929820987
-
-
last accessed May 11, 2015
-
The U.K. Cystic Fibrosis Gene Therapy Consortium. www.cfgenetherapy.org.uk/genetherapy/article/CF-Gene-Therapy-Clinical-Trials (last accessed May 11, 2015).
-
-
-
-
112
-
-
80054087238
-
Pre-clinical evaluation of three nonviral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung
-
McLachlan G, et al. Pre-clinical evaluation of three nonviral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung. Gene Ther 2011;18:996-1005.
-
(2011)
Gene Ther
, vol.18
, pp. 996-1005
-
-
McLachlan, G.1
-
113
-
-
84902660472
-
Aerosol delivery of DNA/liposomes to the lung for cystic fibrosis gene therapy
-
Davies LA, Nunez-Alonso GA, McLachlan G, et al. Aerosol delivery of DNA/liposomes to the lung for cystic fibrosis gene therapy. Hum Gene Ther Clin Dev 2014;25: 97-107.
-
(2014)
Hum Gene Ther Clin Dev
, vol.25
, pp. 97-107
-
-
Davies, L.A.1
Nunez-Alonso, G.A.2
McLachlan, G.3
-
114
-
-
43449111490
-
CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression
-
Hyde SC, et al. CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression. Nat Biotechnol 2008;26:549-551.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 549-551
-
-
Hyde, S.C.1
-
115
-
-
84877593162
-
Changes in physiological, functional and structural markers of cystic fibrosis lung disease with treatment of a pulmonary exacerbation
-
Horsley AR, et al. Changes in physiological, functional and structural markers of cystic fibrosis lung disease with treatment of a pulmonary exacerbation. Thorax 2013;68: 532-539.
-
(2013)
Thorax
, vol.68
, pp. 532-539
-
-
Horsley, A.R.1
-
116
-
-
84885388155
-
The safety profile of a cationic lipidmediated cystic fibrosis gene transfer agent following repeated monthly aerosol administration to sheep
-
Alton EW, et al. The safety profile of a cationic lipidmediated cystic fibrosis gene transfer agent following repeated monthly aerosol administration to sheep. Biomaterials 2013;34:10267-10277.
-
(2013)
Biomaterials
, vol.34
, pp. 10267-10277
-
-
Alton, E.W.1
-
117
-
-
84891742682
-
Toxicology study assessing efficacy and safety of repeated administration of lipid/DNA complexes to mouse lung
-
Alton EW, et al. Toxicology study assessing efficacy and safety of repeated administration of lipid/DNA complexes to mouse lung. Gene Ther 2014;21:89-95.
-
(2014)
Gene Ther
, vol.21
, pp. 89-95
-
-
Alton, E.W.1
-
118
-
-
84923106217
-
Therapeutic genome editing: Prospects and challenges
-
Cox DB, Platt RJ, and Zhang F. Therapeutic genome editing: prospects and challenges. Nat Med 2015;21:121-131.
-
(2015)
Nat Med
, vol.21
, pp. 121-131
-
-
Cox, D.B.1
Platt, R.J.2
Zhang, F.3
-
119
-
-
84890033064
-
Functional repair of CFTR by CRISPR/ Cas9 in intestinal stem cell organoids of cystic fibrosis patients
-
Schwank G, et al. Functional repair of CFTR by CRISPR/ Cas9 in intestinal stem cell organoids of cystic fibrosis patients. Cell Stem Cell 2013;13:653-658.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 653-658
-
-
Schwank, G.1
-
120
-
-
85054130139
-
Correction of the DF508 mutation in the cystic fibrosis transmembrane conductance regulator gene by zinc-finger nuclease homology-directed repair
-
Lee CM, Flynn R, Hollywood JA, et al. Correction of the DF508 mutation in the cystic fibrosis transmembrane conductance regulator gene by zinc-finger nuclease homology-directed repair. Biores Open Access 2012;1: 99-108.
-
(2012)
Biores Open Access
, vol.1
, pp. 99-108
-
-
Lee, C.M.1
Flynn, R.2
Hollywood, J.A.3
|