Correction of the Δf508 mutation in the cystic fibrosis transmembrane conductance regulator gene by zinc-finger nuclease homology-directed repair

BioResearch Open Access

Volumn 1, Issue 3, 2012, Pages 99-103

  Lee, Ciaran M ^a   Flynn, Rowan ^a,b   Hollywood, Jennifer A ^a   Scallan, Martina F ^a   Harrison, Patrick T ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

AAV vectors; DNA repair; Gene therapy; Viral vectors; Zinc finger nuclease

Indexed keywords

COMPLEMENTARY DNA; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; OLIGONUCLEOTIDE; PLASMID VECTOR; VIRUS VECTOR; ZINC FINGER NUCLEASE;

AMPLICON; ARTICLE; BRONCHUS MUCOSA; CELL FUNCTION; CONTROLLED STUDY; CYSTIC FIBROSIS; DNA END JOINING REPAIR; DNA REPAIR; DNA SEQUENCE; DOUBLE STRANDED DNA BREAK; EXON; GENE FREQUENCY; GENE MUTATION; GENE TARGETING; GENE THERAPY; HOMOLOGY DIRECTED REPAIR; HUMAN; HUMAN CELL; INVERTED TERMINAL REPEAT; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 85054130139     PISSN: None     EISSN: 21647860     Source Type: Journal    
DOI: 10.1089/biores.2012.0218     Document Type: Article

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