Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis

Journal of Clinical Investigation

Volumn 97, Issue 6, 1996, Pages 1504-1511

  Zabner, Joseph ^a   Ramsey, Bonnie W ^b   Meeker, David P ^c   Aitken, Moira L ^b   Balfour, Rosemary P ^d   Gibson, Ronald L ^b   Launspach, Jan ^a   Moscicki, Richard A ^c   Richards, Susan M ^c   Standaert, Thomas A ^b   Williams Warren, Judy ^b   Wadsworth, Samuel C ^c   Smith, Alan E ^c   Welsh, Michael J ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

^c GENZYME CORPORATION   (United States)

^d 500 EMRB ^*

Author keywords

airway; chloride ion channel; gene transfer; immune response

Indexed keywords

CHLORIDE; CYTOKINE; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; ION CHANNEL; NEUTRALIZING ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; VIRUS VECTOR;

ADENOVIRUS; ADULT; ANTIBODY PRODUCTION; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CHLORIDE CONDUCTANCE; CLINICAL ARTICLE; CLINICAL TRIAL; CYSTIC FIBROSIS; FEMALE; GENE MUTATION; GENE THERAPY; GENE TRANSFER; HUMAN; HUMORAL IMMUNITY; MALE; MEMBRANE CONDUCTANCE; NOSE MUCOSA; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; VIRUS RECOMBINANT;

EID: 13344286312     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118573     Document Type: Article

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