Safety and Biological Efficacy of a Lipid-CFTR Complex for Gene Transfer in the Nasal Epithelium of Adult Patients with Cystic Fibrosis

Molecular Therapy

Volumn 1, Issue 1, 2000, Pages 105-114

  Noone, Peadar G ^a   Hohneker, Katherine W ^a   Zhou, Zhaoqing ^a   Johnson, Larry G ^a   Foy, Carla ^a   Gipson, Clay ^a   Jones, Kim ^a   Noah, Terry L ^a   Leigh, Margaret W ^a   Schwartzbach, Caryl ^b   Efthimiou, John ^b   Pearlman, Rodney ^c   Boucher, Richard C ^a   Knowles, Michael R ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b GLAXOSMITHKLINE   (United States)

^c Urigen Pharmaceuticals Inc   (United States)

Author keywords

Liposome; gene transfer; cystic fibrosis; CFTR; EDMPC

Indexed keywords

CFTR PROTEIN, HUMAN; CHLORIDE; COMPLEMENTARY DNA; LIPOSOME; PRIMER DNA; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYSTIC FIBROSIS; DOUBLE BLIND PROCEDURE; ELECTRIC CONDUCTIVITY; EPITHELIUM; FEMALE; GENE THERAPY; GENE TRANSFER; GENETICS; HUMAN; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; NOSE MUCOSA; NUCLEOTIDE SEQUENCE; SAFETY;

ADULT; BASE SEQUENCE; CHLORIDES; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DNA PRIMERS; DNA, COMPLEMENTARY; DOUBLE-BLIND METHOD; ELECTRIC CONDUCTIVITY; EPITHELIUM; FEMALE; GENE THERAPY; GENE TRANSFER TECHNIQUES; HUMANS; LIPOSOMES; MALE; MIDDLE AGED; NASAL MUCOSA; SAFETY;

EID: 0033660570     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.1999.0009     Document Type: Article

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