Protection of Cftr knockout mice from acute lung infection by a helper-dependent adenoviral vector expressing Cftr in airway epithelia

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 26, 2003, Pages 15364-15369

  Koehler, David R ^a,d   Sajjan, Umadevi ^a   Chow, Yu Hua ^a,d   Martin, Bernard ^a   Kent, Geraldine ^b   Tanswell, A Keith ^a,c,d   McKerlie, Colin ^a,d   Forstner, Janet F ^a   Hu, Jim ^a,c,d  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

Burkholderia cepacia complex; Cystic fibrosis; Cytokeratin 18

Indexed keywords

ADENOVIRUS VECTOR; CYTOKERATIN 18; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COUNT; BURKHOLDERIA CEPACIA; CELL CULTURE; CELL STRAIN COS1; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYSTIC FIBROSIS; GENE THERAPY; HISTOPATHOLOGY; INFECTION SENSITIVITY; KNOCKOUT MOUSE; LUNG INFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM;

ANALYSIS OF VARIANCE; ANIMALS; BURKHOLDERIA INFECTIONS; CERCOPITHECUS AETHIOPS; COS CELLS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC VECTORS; HUMANS; LUNG; MICE; MICE, KNOCKOUT; RESPIRATORY MUCOSA; RESPIRATORY TRACT INFECTIONS; TRANSFECTION;

ADENOVIRIDAE; ANIMALIA; BACTERIA (MICROORGANISMS); BURKHOLDERIA; BURKHOLDERIA CEPACIA; BURKHOLDERIA CEPACIA COMPLEX;

EID: 0347364650     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.2436478100     Document Type: Article

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