A largely random AAV integration profile after LPLD gene therapy

Nature Medicine

Volumn 19, Issue 7, 2013, Pages 889-891

  Kaeppel, Christine ^a   Beattie, Stuart G ^b,d   Fronza, Raffaele ^a   Van Logtenstein, Richard ^b   Salmon, Florence ^b   Schmidt, Sabine ^a   Wolf, Stephan ^a   Nowrouzi, Ali ^a   Glimm, Hanno ^a   Von Kalle, Christof ^a   Petry, Harald ^b   Gaudet, Daniel ^c   Schmidt, Manfred ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIQURE   (Netherlands)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PARVOVIRUS VECTOR;

ARTICLE; CARCINOGENICITY; CPG ISLAND; DNA INTEGRATION; GENE THERAPY; HUMAN; MITOCHONDRIAL GENOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIRUS GENE;

ANIMALS; BINDING SITES; DEPENDOVIRUS; GENETIC THERAPY; GENETIC VECTORS; HUMANS; HYPERLIPOPROTEINEMIA TYPE I; INJECTIONS, INTRAMUSCULAR; LIPOPROTEIN LIPASE; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; MUTAGENESIS, INSERTIONAL; TRANSCRIPTOME; VIRUS INTEGRATION;

ADENO-ASSOCIATED VIRUS;

EID: 84880289352     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3230     Document Type: Article

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