-
1
-
-
0000026508
-
Cystic fibrosis
-
C.R. Scriver, A.L. Beaudet, W.S. Sly, and D. Valle, editors. McGraw-Hill, Inc., New York
-
Welsh, M.J., L.-C. Tsui, T.F. Boat, and A.L. Beaudet. 1995. Cystic fibrosis. In The Metabolic and Molecular Basis of Inherited Disease, C.R. Scriver, A.L. Beaudet, W.S. Sly, and D. Valle, editors. McGraw-Hill, Inc., New York. 3799-3876.
-
(1995)
The Metabolic and Molecular Basis of Inherited Disease
, pp. 3799-3876
-
-
Welsh, M.J.1
Tsui, L.-C.2
Boat, T.F.3
Beaudet, A.L.4
-
2
-
-
0027377523
-
Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis
-
Zabner, J., L.A. Couture, R.J. Gregory, S.M. Graham, A.E. Smith, and M.J. Welsh. 1993. Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis. Cell. 75:207-216.
-
(1993)
Cell
, vol.75
, pp. 207-216
-
-
Zabner, J.1
Couture, L.A.2
Gregory, R.J.3
Graham, S.M.4
Smith, A.E.5
Welsh, M.J.6
-
3
-
-
0028168641
-
Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis
-
Crystal, R.G., N.G. McElvaney, M.A. Rosenfeld, C.S. Chu, A. Mastrangeli, J.G. Hay, S.L. Brody, H.A. Jaffe, N.T. Eissa, and C. Danel. 1994. Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis. Nat. Genet. 8:42-51.
-
(1994)
Nat. Genet.
, vol.8
, pp. 42-51
-
-
Crystal, R.G.1
McElvaney, N.G.2
Rosenfeld, M.A.3
Chu, C.S.4
Mastrangeli, A.5
Hay, J.G.6
Brody, S.L.7
Jaffe, H.A.8
Eissa, N.T.9
Danel, C.10
-
4
-
-
0028802876
-
Modification of nasal epithelial potential differences of individuals with cystic fibrosis consequent to local administration of a normal CFTR cDNA adenovirus gene transfer vector
-
Hay, J.G., N.G. McElvaney, J. Herena, and R.G. Crystal. 1995. Modification of nasal epithelial potential differences of individuals with cystic fibrosis consequent to local administration of a normal CFTR cDNA adenovirus gene transfer vector. Hum. Gene Ther. 6:1487-1496.
-
(1995)
Hum. Gene Ther.
, vol.6
, pp. 1487-1496
-
-
Hay, J.G.1
McElvaney, N.G.2
Herena, J.3
Crystal, R.G.4
-
5
-
-
13344286312
-
Repeat administration of an adenovirus vector encoding CFTR to the nasal epithelium of patients with cystic fibrosis
-
Zabner, J., B.W. Ramsey, D.P. Meeker, M.I. Aitken, R.P. Balfour, R.L. Gibson, J. Launspach, R.A. Moscicki, S.M. Richards, T.A. Standaert, et al. 1996. Repeat administration of an adenovirus vector encoding CFTR to the nasal epithelium of patients with cystic fibrosis. J. Clin. Invest. 97:1504-1511.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 1504-1511
-
-
Zabner, J.1
Ramsey, B.W.2
Meeker, D.P.3
Aitken, M.I.4
Balfour, R.P.5
Gibson, R.L.6
Launspach, J.7
Moscicki, R.A.8
Richards, S.M.9
Standaert, T.A.10
-
6
-
-
0029100239
-
A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis
-
Knowles, M.R., K.W. Hohneker, Z. Zhou, J.C. Olsen, T.L. Noah, P.C. Hu, M.W. Leigh, J.F. Engelhardt, L.J. Edwards, K.R. Jones, et al. 1995. A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis. N. Engl. J. Med. 333:823-831.
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 823-831
-
-
Knowles, M.R.1
Hohneker, K.W.2
Zhou, Z.3
Olsen, J.C.4
Noah, T.L.5
Hu, P.C.6
Leigh, M.W.7
Engelhardt, J.F.8
Edwards, L.J.9
Jones, K.R.10
-
7
-
-
0026459987
-
Aerosol gene delivery in vivo
-
Stribling, R., E. Brunette, D. Liggitt, K. Gaensler, and R. Debs. 1992. Aerosol gene delivery in vivo. Proc. Natl. Acad. Sci. USA. 89:11277-11281.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 11277-11281
-
-
Stribling, R.1
Brunette, E.2
Liggitt, D.3
Gaensler, K.4
Debs, R.5
-
8
-
-
0028056371
-
Aerosol and intravenous transfection of human α1-antitrypsin gene to lungs of rabbits
-
Canonico, A.E., J.T. Conary, B.O. Meyrick, and K.L. Brigham. 1994. Aerosol and intravenous transfection of human α1-antitrypsin gene to lungs of rabbits. Am. J. Respir. Cell Mol. Biol. 10:24-29.
-
(1994)
Am. J. Respir. Cell Mol. Biol.
, vol.10
, pp. 24-29
-
-
Canonico, A.E.1
Conary, J.T.2
Meyrick, B.O.3
Brigham, K.L.4
-
9
-
-
0027361622
-
Non-invasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice
-
Alton, E.W., P.G. Middleton, N.J. Caplen, S.N. Smith, D.M. Steel, F.M. Munkonge, P.K. Jeffery, D.M. Geddes, S.L. Hart, R. Williamson, et al. 1993. Non-invasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice. Nat. Genet. 5:135-142.
-
(1993)
Nat. Genet.
, vol.5
, pp. 135-142
-
-
Alton, E.W.1
Middleton, P.G.2
Caplen, N.J.3
Smith, S.N.4
Steel, D.M.5
Munkonge, F.M.6
Jeffery, P.K.7
Geddes, D.M.8
Hart, S.L.9
Williamson, R.10
-
10
-
-
0027475701
-
Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy
-
Hyde, S.C., D.R. Gill, C.F. Higgins, A.E. Trezise, L.J. MacVinish, A.W. Cuthbert, R. Ratcliff, M.J. Evans, and W.H. Colledge. 1993. Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy. Nature (Lond.). 362:250-255.
-
(1993)
Nature (Lond.)
, vol.362
, pp. 250-255
-
-
Hyde, S.C.1
Gill, D.R.2
Higgins, C.F.3
Trezise, A.E.4
MacVinish, L.J.5
Cuthbert, A.W.6
Ratcliff, R.7
Evans, M.J.8
Colledge, W.H.9
-
11
-
-
0029875289
-
Characterization of plasmid DNA transfer into mouse skeletal muscle: Evaluation of uptake mechanism, expression and secretion of gene products into blood
-
Levy, M.Y., L.G. Barron, K.B. Meyer, and F.C. Szoka, Jr. 1996. Characterization of plasmid DNA transfer into mouse skeletal muscle: evaluation of uptake mechanism, expression and secretion of gene products into blood. Gene Ther. 3:201-211.
-
(1996)
Gene Ther.
, vol.3
, pp. 201-211
-
-
Levy, M.Y.1
Barron, L.G.2
Meyer, K.B.3
Szoka Jr., F.C.4
-
12
-
-
0029036884
-
Lung-specific direct in vivo gene transfer with recombinant plasmid DNA
-
Tsan, M.F., J.E. White, and B. Shepard. 1995. Lung-specific direct in vivo gene transfer with recombinant plasmid DNA. Am. J. Physiol. 268:L1052-L1056.
-
(1995)
Am. J. Physiol.
, vol.268
-
-
Tsan, M.F.1
White, J.E.2
Shepard, B.3
-
13
-
-
0028913411
-
Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
-
Caplen, N.J., E.W. Alton, P.G. Middleton, J.R. Dorin, B.J. Stevenson, X. Gao, S.R. Durham, P.K. Jeffery, M.E. Hodson, C. Coutelle, et al. 1995. Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Nat. Med. 1:39-46.
-
(1995)
Nat. Med.
, vol.1
, pp. 39-46
-
-
Caplen, N.J.1
Alton, E.W.2
Middleton, P.G.3
Dorin, J.R.4
Stevenson, B.J.5
Gao, X.6
Durham, S.R.7
Jeffery, P.K.8
Hodson, M.E.9
Coutelle, C.10
-
14
-
-
8244238394
-
A placebo-controlled study of liposome-mediated gene transfer to the nasal epithelium of patients with cystic fibrosis
-
Gill, D.R., K.W. Southern, K.A. Mofford, T. Seddon, L. Huang, F. Sorgi, A. Thomson, L.J. MacVinish, R. Ratcliff, D. Bilton, et al. 1997. A placebo-controlled study of liposome-mediated gene transfer to the nasal epithelium of patients with cystic fibrosis. Gene Ther. 4:199-209.
-
(1997)
Gene Ther.
, vol.4
, pp. 199-209
-
-
Gill, D.R.1
Southern, K.W.2
Mofford, K.A.3
Seddon, T.4
Huang, L.5
Sorgi, F.6
Thomson, A.7
MacVinish, L.J.8
Ratcliff, R.9
Bilton, D.10
-
15
-
-
8244245761
-
Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
-
Porteous, D.J., J.R. Dorin, G. McLachlan, H. Davidson-Smith, H. Davidson, B.J. Stevenson, A.C. Carothers, W.A.H. Wallace, S. Moralee, C. Hoenes, et al. 1997. Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Gene Ther. 4:210-218.
-
(1997)
Gene Ther.
, vol.4
, pp. 210-218
-
-
Porteous, D.J.1
Dorin, J.R.2
McLachlan, G.3
Davidson-Smith, H.4
Davidson, H.5
Stevenson, B.J.6
Carothers, A.C.7
Wallace, W.A.H.8
Moralee, S.9
Hoenes, C.10
-
16
-
-
19244363903
-
Detailed analysis of structures and formulations of cationic lipids lor efficient gene transfer to the lung
-
Lee, E.R., J. Marshall, C.S. Siegel, C. Jiang, N.S. Yew, M.R. Nichels, J.B. Nietupski, R.J. Ziegler, M. Lane, K.X. Wang, et al. 1996. Detailed analysis of structures and formulations of cationic lipids lor efficient gene transfer to the lung. Hum. Gene Ther. 7:1701-1717.
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 1701-1717
-
-
Lee, E.R.1
Marshall, J.2
Siegel, C.S.3
Jiang, C.4
Yew, N.S.5
Nichels, M.R.6
Nietupski, J.B.7
Ziegler, R.J.8
Lane, M.9
Wang, K.X.10
-
17
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
-
(1987)
Anal. Biochem.
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
18
-
-
0029854816
-
Asymmetry in the nasal mucociliary transport rate
-
Nuutinen, J. 1996. Asymmetry in the nasal mucociliary transport rate. Laryngoscope. 106:1424-1428.
-
(1996)
Laryngoscope
, vol.106
, pp. 1424-1428
-
-
Nuutinen, J.1
-
19
-
-
0029056088
-
Cellular and molecular barriers to gene transfer by a cationic lipid
-
Zabner, J., A.J. Fasbender, T. Moninger, K.A. Poellinger, and M.J. Welsh. 1995. Cellular and molecular barriers to gene transfer by a cationic lipid. J. Biol. Chem. 270:18997-19007.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18997-19007
-
-
Zabner, J.1
Fasbender, A.J.2
Moninger, T.3
Poellinger, K.A.4
Welsh, M.J.5
-
20
-
-
0031013538
-
Loss of binding and entry of liposome-DNA complexes decreases transfection efficiency in differentiated airway epithelial cells
-
Matsui, H., L.G. Johnson, S.H. Randell, and R.C. Boucher. 1997. Loss of binding and entry of liposome-DNA complexes decreases transfection efficiency in differentiated airway epithelial cells. J. Biol. Chem. 272:1117-1126.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 1117-1126
-
-
Matsui, H.1
Johnson, L.G.2
Randell, S.H.3
Boucher, R.C.4
-
21
-
-
0029078539
-
Intratracheal gene delivery to the mouse airway: Characterization of plasmid DNA expression and pharmacokinetics
-
Meyer, K.B., M.M. Thompson, M.Y. Levy, L.G. Barron, and F.C. Szoka, Jr. 1995. Intratracheal gene delivery to the mouse airway: characterization of plasmid DNA expression and pharmacokinetics. Gene Ther. 2:450-460.
-
(1995)
Gene Ther.
, vol.2
, pp. 450-460
-
-
Meyer, K.B.1
Thompson, M.M.2
Levy, M.Y.3
Barron, L.G.4
Szoka Jr., F.C.5
-
23
-
-
0025231388
-
Direct gene transfer into mouse muscle in vivo
-
Wolff, J.A., R.W. Malone, P. Williams, W. Chong, G. Acsadi, A. Jani, and P.L. Felgner. 1990. Direct gene transfer into mouse muscle in vivo. Science (Wash. DC). 247:1465-1468.
-
(1990)
Science (Wash. DC)
, vol.247
, pp. 1465-1468
-
-
Wolff, J.A.1
Malone, R.W.2
Williams, P.3
Chong, W.4
Acsadi, G.5
Jani, A.6
Felgner, P.L.7
-
24
-
-
0029744337
-
Long-term expression of erythropoietin in the systemic circulation of mice after intramuscular injection of a plasmid DNA vector
-
Tripathy, S.K., E.C. Svensson, G.B. Black, E. Goldwasser, M. Margalith, P.M. Hobart, and J.M. Leiden. 1996. Long-term expression of erythropoietin in the systemic circulation of mice after intramuscular injection of a plasmid DNA vector. Proc. Natl. Acad. Sci. USA. 93:10876-10880.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10876-10880
-
-
Tripathy, S.K.1
Svensson, E.C.2
Black, G.B.3
Goldwasser, E.4
Margalith, M.5
Hobart, P.M.6
Leiden, J.M.7
-
25
-
-
0029891426
-
Direct gene transfer to mouse melanoma by intratumor injection of free DNA
-
Yang, J.P., and L. Huang. 1996. Direct gene transfer to mouse melanoma by intratumor injection of free DNA. Gene Ther. 3:542-548.
-
(1996)
Gene Ther.
, vol.3
, pp. 542-548
-
-
Yang, J.P.1
Huang, L.2
-
26
-
-
0028670903
-
Gene expression following direct injection of DNA into liver
-
Hickman, M.A., R.W. Malone, K. Lehmann-Bruinsma, T.R. Sih, D. Knoell, F.C. Szoka, R. Walzem, D.M. Carlson, and J.S. Powell. 1994. Gene expression following direct injection of DNA into liver. Hum. Gene Ther. 5:1477-1483.
-
(1994)
Hum. Gene Ther.
, vol.5
, pp. 1477-1483
-
-
Hickman, M.A.1
Malone, R.W.2
Lehmann-Bruinsma, K.3
Sih, T.R.4
Knoell, D.5
Szoka, F.C.6
Walzem, R.7
Carlson, D.M.8
Powell, J.S.9
-
27
-
-
0029781318
-
Naked DNA delivered intraportally expresses efficiently in hepatocytes
-
Budker, V., G. Zhang, S. Knechtle, and J.A. Wolff. 1996. Naked DNA delivered intraportally expresses efficiently in hepatocytes. Gene Ther. 3:593-598.
-
(1996)
Gene Ther.
, vol.3
, pp. 593-598
-
-
Budker, V.1
Zhang, G.2
Knechtle, S.3
Wolff, J.A.4
-
29
-
-
0026557261
-
Behavior of genes directly injected into the rat heart in vivo
-
Buttrick, P.M., A. Kass, R.N. Kitsis, M.L. Kaplan, and L.A. Leinwand. 1992. Behavior of genes directly injected into the rat heart in vivo. Circ. Res. 70: 193-198.
-
(1992)
Circ. Res.
, vol.70
, pp. 193-198
-
-
Buttrick, P.M.1
Kass, A.2
Kitsis, R.N.3
Kaplan, M.L.4
Leinwand, L.A.5
-
30
-
-
0029874283
-
Direct gene delivery to synovium. An evaluation of potential vectors in vitro and in vivo
-
Nita, I., S.C. Ghivizzani, J. Galea-Lauri, G. Bandara, H.I. Georgescu, P.D. Robbins, and C.H. Evans. 1996. Direct gene delivery to synovium. An evaluation of potential vectors in vitro and in vivo. Arthritis Rheum. 39:820-828.
-
(1996)
Arthritis Rheum.
, vol.39
, pp. 820-828
-
-
Nita, I.1
Ghivizzani, S.C.2
Galea-Lauri, J.3
Bandara, G.4
Georgescu, H.I.5
Robbins, P.D.6
Evans, C.H.7
-
31
-
-
16944361840
-
A concentrated and stable aerosol formulation of cationic lipid: DNA complexes giving high level gene expression in mouse lung
-
Eastman, S.-J., M.J. Lukason, J.D. Tousignant, H. Murray, M.D. Lane, J.A. St. George, G.Y. Akita, M. Cherry, S.H. Cheng, and R.K. Scheule. 1997. A concentrated and stable aerosol formulation of cationic lipid: DNA complexes giving high level gene expression in mouse lung. Hum. Gene Ther. 8:765-773.
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 765-773
-
-
Eastman, S.-J.1
Lukason, M.J.2
Tousignant, J.D.3
Murray, H.4
Lane, M.D.5
St. George, J.A.6
Akita, G.Y.7
Cherry, M.8
Cheng, S.H.9
Scheule, R.K.10
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