Serum from calorie-restricted animals delays senescence and extends the lifespan of normal human fibroblasts in vitro

Aging

Volumn 7, Issue 3, 2015, Pages 152-166

  de Cabo, Rafael ^a   Liu, Lijuan ^a   Ali, Ahmed ^a   Price, Nathan ^a   Zhang, Jing ^a   Wang, Mingyi ^a   Lakatta, Edward ^a   Irusta, Pablo M ^a,b  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Aging; Caloric restriction; Human diploid fibroblasts; Lifespan extension; Senescence; SIRT1

Indexed keywords

BETA GALACTOSIDASE; CONDITIONED MEDIUM; GELATINASE A; GLB1 PROTEIN, HUMAN; MMP2 PROTEIN, HUMAN; PROTEIN P53; SIRT1 PROTEIN, HUMAN; SIRTUIN 1;

ANIMAL; CALORIC RESTRICTION; CELL AGING; CELL LINE; CONDITIONED MEDIUM; DIPLOIDY; DOWN REGULATION; FIBROBLAST; FISCHER 344 RAT; HUMAN; LONGEVITY; MALE; METABOLISM; PHENOTYPE; PHYSIOLOGY; SERUM;

ANIMALS; BETA-GALACTOSIDASE; CALORIC RESTRICTION; CELL AGING; CELL LINE; CULTURE MEDIA, CONDITIONED; DIPLOIDY; DOWN-REGULATION; FIBROBLASTS; HUMANS; LONGEVITY; MALE; MATRIX METALLOPROTEINASE 2; PHENOTYPE; RATS, INBRED F344; SERUM; SIRTUIN 1; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84929334583     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100719     Document Type: Article

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