Calorie restriction delays the progression of lesions to pancreatic cancer in the LSL-KrasG12D; Pdx-1/Cre mouse model of pancreatic cancer

Experimental Biology and Medicine

Volumn 238, Issue 7, 2013, Pages 787-797

  Lanza Jacoby, Susan ^a   Yan, Guang ^a   Radice, Glenn ^a   LePhong, Christopher ^a   Baliff, Jeffrey ^a   Hess, Rachael ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

calorie restriction; Glut1; intermittent calorie restriction; LSL KrasG12D; mammalian target of rapamycin (mTOR); pancreatic cancer; Pdx 1 Cre mice

Indexed keywords

ADIPONECTIN; CYCLINE; GLUCOSE; GLUCOSE TRANSPORTER 1; LEPTIN; MAMMALIAN TARGET OF RAPAMYCIN; SIRTUIN 1; SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CALORIC RESTRICTION; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DIETARY INTAKE; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; INCIDENCE; MOUSE; NONHUMAN; PANCREAS ADENOCARCINOMA; PRECANCER; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

CALORIE RESTRICTION; GLUT1; INTERMITTENT CALORIE RESTRICTION; LSL-KRASG12D; MAMMALIAN TARGET OF RAPAMYCIN (MTOR); PANCREATIC CANCER; PDX-1/CRE MICE;

ADIPONECTIN; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CALORIC RESTRICTION; CELL PROLIFERATION; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEEDING BEHAVIOR; HOMEODOMAIN PROTEINS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; INTEGRASES; LEPTIN; MICE; MICE, TRANSGENIC; ORGAN SIZE; PANCREAS; PANCREATIC DUCTS; PANCREATIC NEOPLASMS; PHOSPHORYLATION; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTO-ONCOGENE PROTEINS P21(RAS); SIGNAL TRANSDUCTION; SIRTUIN 1; TRANS-ACTIVATORS;

EID: 84884171074     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/1535370213493727     Document Type: Article

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