Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2

Cancer Research

Volumn 58, Issue 16, 1998, Pages 3743-3750

  Deryugina, Elena I ^a   Bourdon, Mario A ^a   Reisfeld, Ralph A ^b   Strongin, Alex ^a  

^a La Jolla Institute for Experimental Medicine   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; COLLAGEN; COMPLEMENTARY DNA; GELATINASE A; INTEGRIN; ORGANOMERCURY COMPOUND; RECOMBINANT ENZYME; TISSUE INHIBITOR OF METALLOPROTEINASE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MICROTUBULE; PRIORITY JOURNAL; TUMOR CELL;

COLLAGEN; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; FIBROSARCOMA; GELATINASES; GLIOMA; HUMANS; INTEGRINS; MATRIX METALLOPROTEINASE 2; METALLOENDOPEPTIDASES; MOLECULAR WEIGHT; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0032529241     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Birkedal-Hansen, H., Moore, W. G. I., Bodden, M. K., Windsor, L. J., Birkedal-Hansen, B., DeCarlo, A., and Engler, J. A. Matrix metalloproteinases: a review. Crit. Rev. Oral Biol. Med., 4: 197-250, 1993.
2. Sato, H., Takino, H., Okada, Y., Cao, J., Yamamoto, E., and Seiki, M. A matrix metalloproteinase expressed on the surface of invasive tumor cells. Nature (Lond.), 370: 61-65, 1994.
3. Strongin, A. Y., Collier, I., Bannikov, G., Manner, B. L., Grant, G. A., and Goldberg, G. I. Mechanism of cell surface activation of 72-kDa type IV collagenase. J. Biol. Chem., 270: 5331-5338, 1995.
4. Aznavoorian, S., Murphy, A. N., Steuer-Stevenson, W. G., and Liotta, L. A. Molecular aspects of tumor invasion and metastasis. Cancer (Phila.), 71: 1368-1383, 1993.
5. Yamamoto, M., Mohanam, S., Sawaya, R., Fuller, G. N., Seiki, M., Sato, H., Gokaslan, Z-L., Liotta, L. A., Nicolson, G. L., and Rao, J. S. Differential expression of membrane type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro. Cancer Res., 56: 384-392, 1996.
6. 3. Cell, 85: 683-693, 1996.
7. Deryugina, E. I., Bourdon, M. A., Luo, G-X., Reisfeld, R. A., and Strongin, A. Matrix metalloproteinase activation modulates glioma cell migration. J. Cell Sci., 110: 2473-2482, 1997.
8. Nakahara, H., Howard, L., Thompson, E. W., Sato, H., Seiki, M., Yeh, Y., and Chen, W. T. Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadipodia is required for cell invasion. Proc. Natl. Acad. Sci. USA, 94: 7959-7964, 1997.
9. Pei, D., and Weiss, S. J. Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase-1 process progelatinase A and express intrinsic matrix-degrading activity, J. Biol. Chem., 271: 9135-9140, 1996.
10. Strongin, A. Y., Marmer, B. L., Grant, G. A., and Goldberg, G. I. Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TIMP-2. J. Biol. Chem., 268: 14033-14039, 1993.
11. Ko, Y. C., Langley, K. E., Mendiaz, E. A., Parker, V. P., Taylor, S. M., and DeClerck, Y. A. The C-terminal domain of tissue inhibitor of metalloproteinases-2 is required for cell binding but not for antimetalloproteinase activity. Biochem. Biophys. Res. Commun., 236: 100-105, 1997.
12. Zucker, S., Drews, M., Conner, C., Foda, H. D., DeClerck, Y. A., Langley, K. E., Bahou, W. F., Docherty, A. J. P., and Cao, J. Tissue inhibitor of metalloproteinase-2 (TIMP-2) binds to the catalytic domain of the cell surface receptor, membrane type 1-matrix metalloproteinase (MT1-MMP). J. Biol. Chem., 273: 1216-1222, 1998.
13. Goldberg, G. I., Marmer, B. L., Grant, G. A., Eisen, A. Z., Wilhelm, S., and He, C. Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteinases designated TIMP-2. Proc. Natl. Acad. Sci. USA, 86: 8207-8211, 1989.
14. Will, H., Atkinson, S. J., Butler, G. S., Smith, B., and Murphy, G. The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-2 and TIMP-3. J. Biol. Chem., 271: 17119-17123, 1996.
15. Gullberg, D., Tingstrom, A., Thuresson, A-C., Olsson, L., Terracio, L., Borg, T. K., and Rubin, K. β1 Integrin-mediated collagen gel contraction is stimulated by PDGF. Exp. Cell Res., 186: 264-272, 1990.
16. Seltzer, J. L., Lee, A-Y., Akers, K. T., Sudbeck, B., Southon, E., Wayner, E. A., and Eisen, A. Z. Activation of 72-kDa type IV collagenase/gelatinase by normal fibroblasts in collagen lattices is mediated by integrin receptors but is not related to lattice contraction. Exp. Cell Res., 213: 365-374, 1994.
17. 1, integrin complex in collagen gel contraction in vitro by fibroblasts. J. Cell. Physiol., 165: 425-437, 1995.
18. 1, integrins. J. Cell Biol., 131: 1903-1915, 1995.
19. 1 integrin expression in osteogenic cells. J. Biol. Chem., 270: 376-382, 1995.
20. Thieszen, S. L., Dalton, M., Gadson, P. F., Patterson, E., and Rosenquist, T. H. Embryonic lineage of vascular smooth muscle cells determines responses to collagen matrices and integrin receptor expression. Exp. Cell Res., 227: 135-145, 1996.
21. Stephens, P., Genever, P. G., Wood, E. J., and Raxworthy, J. Integrin receptor involvement in actin cable formation in an in vitro model of events associated with wound contraction. Int. J. Biochem. Cell Biol., 29: 121-128, 1997.
22. Davis, G.E., and Camarillo, C. W. Regulation of endothelial cell morphogenesis by integrins, mechanical forces, and matrix guidance pathways. Exp. Cell Res., 276: 113-123, 1995.
23. Eastwood, M., Porter, R., Khan, U., McGrouther, G., and Brown, R. Quantitative analysis of collagen gel contractile forces generated by dermal fibroblasts and the relationship to cell morphology. J. Cell. Physiol., 166: 33-42, 1996.
24. Yamato, M., Adachi, E., Yamamoto, K., and Hayashi, T. Condensation of collagen fibrils to the direct vicinity of fibroblasts as a cause of gel contraction. J. Biochem. (Tokyo), 117: 940-946, 1995.
25. Allenberg, M., Weinstein, T., Li, I., and Silwerman, M. Activation of procollagenase IV by cytochalasin D and concanavalin A in cultured rat mesanglial cells: linkage to cytoskeletal reorganization. J. Am. Soc. Nephrol., 10: 1760-1770, 1994.
26. Tomasek, J. J., Halliday, N. L., Updike, D. L., Ahern-Moore, S., Vu, T-K. H., Liu, R. W., and Howard, E. Gelatinase A activation is regulated by the organization of the polymerized actin cytoskeleton. J. Biol. Chem., 272: 7482-7487, 1997.
27. Kolodney, M. S., and Elson, E. L. Contraction due to microtubule disruption is associated with increased phosphorylation of myosin regulatory light chain. Proc. Natl. Acad. Sci. USA, 92: 10252-10256, 1995.
28. Lee, Y-R., Oshita, Y., Tsuboi, R., and Ogawa, H. Combination of insulin-like growth factor (IGF)-I and IGF-binding protein-1 promotes fibroblast-embedded collagen gel contraction. Endocrinology, 137: 5278-5283, 1996.
29. Moulin, V., Auger, F. A., O'Connor-McCourt, M., and Germain, L. Fetal and postnatal sera differentially modulate human dermal fibroblast phenotypic and functional features in vitro. J. Cell. Physiol., 171: 1-10, 1997.
30. Vemon, R. B., and Sage, H. Contraction of fibrillar type I collagen by endothelial cells: a study in vitro. J. Cell. Biochem., 60: 185-197, 1996.
31. Tuan, T-L., Song, A., Chang, S., Younai, S., and Nimni, M. E. In vitro fibroplasia: matrix contraction, cell growth, and collagen production of fibroblasts cultured in fibrin gels. Exp. Cell Res., 223: 127-134, 1996.
32. Asaga, H., Kikuchi, S., and Yoshizato, K. Collagen gel contraction by fibroblasts requires cellular fibronectin but not plasma fibronectin. Exp. Cell Res., 193: 442-448, 1986.
33. Bittner, K., Liszio, C., Blumberg, P., Schönherr, E., and Kresse, H. Modulation of collagen gel contraction by decorin. Biochem. J., 314: 159-166, 1996.
34. Chiquet-Ehrismann, R., Tannheimer, M., Koch, M., Brunner, A., Spring, J., Martin, D., Baumgartner, S., and Chiquet, M. Tenascin-C expression by fibroblasts is elevated in stressed collagen gels. J. Cell Biol., 127: 2093-2101, 1994.
35. II-induced DNA synthesis and collagen contraction. J. Clin. Investig., 98: 2218-2227, 1996.
36. Frisch, S. M., Reich, R., Collier, I. E., Genrich, T. L., Martin, G., and Goldberg, G. I. Adenovirus E1A represses protease gene expression and inhibits metastasis of human tumor cells. Oncogene, 5: 75-83, 1990.
37. Deryugina, E. I., Luo, G-X., Reisfeld, R. A., Bourdon, M. A., and Strongin, A. Tumor cell invasion through Matrigel is regulated by activated matrix metalloproteinase-2. Anticancer Res., 17: 3201-3210, 1997.
38. Goldberg, G. I., Strongin, A., Collier, I. E., Genrich, T., and Manner, B. L. Interaction of 92-kDa type IV collagenase with the tissue inhibitor of metalloproteinases prevents dimerization, complex formation with interstitial collagenase, and activation of the proenzyme with stromelysin. J. Biol. Chem., 267: 4583-4591, 1992.
39. v integrin subunit. Hybridoma, 15: 279-288, 1996.
40. Guidry, C., and Grinnell, F. Studies of the mechanism of hydrated collagen gel reorganization by human skin fibroblasts, J. Cell Sci., 79: 67-81, 1985.
41. Gomez, D. E., Alonso, D. F., Yoshiji, H., and Thorgeirsson, U. P. Tissue inhibitors of metalloproteinases: structure, regulation and biological functions. Eur. J. Cell Biol., 74: 111-122, 1997.
42. Danowski, B. A. Fibroblast contractility and actin organization are stimulated by microtubule inhibitors. J. Cell Sci., 93: 255-266, 1989.
43. Vasquez, R. J., Howel, B., Yvon, A-M. C., Wadsworth, P., and Cassimeris, L. Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro. Mol. Biol. Cell, 8: 973-985, 1997.