-
1
-
-
12444279265
-
On the origin of cancer cells
-
Warburg O. On the origin of cancer cells. Science 1956;123:309-14.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
2
-
-
28544446058
-
Mitochondrial tumour suppressors: A genetic and biochemical update
-
Gottlieb E, Tomlinson IP. Mitochondrial tumour suppressors: a genetic and biochemical update. Nat Rev Cancer 2005;5:857-66.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 857-866
-
-
Gottlieb, E.1
Tomlinson, I.P.2
-
3
-
-
2542561169
-
Akt stimulates aerobic glycolysis in cancer cells
-
Elstrom RL, Bauer DE, Buzzai M, et al. Akt stimulates aerobic glycolysis in cancer cells. Cancer Res 2004;64:3892-9.
-
(2004)
Cancer Res
, vol.64
, pp. 3892-3899
-
-
Elstrom, R.L.1
Bauer, D.E.2
Buzzai, M.3
-
4
-
-
14744284637
-
Multifaceted roles of glycolytic enzymes
-
Kim JW, Dang CV. Multifaceted roles of glycolytic enzymes. Trends Biochem Sci 2005;30:142-50.
-
(2005)
Trends Biochem Sci
, vol.30
, pp. 142-150
-
-
Kim, J.W.1
Dang, C.V.2
-
5
-
-
21744442902
-
Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis
-
Li F, Wang Y, Zeller KI, et al. Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis. Mol Cell Biol 2005;25:6225-34.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 6225-6234
-
-
Li, F.1
Wang, Y.2
Zeller, K.I.3
-
6
-
-
3543144346
-
E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis
-
Powers JT, Hong S, Mayhew CN, Rogers PM, Knudsen ES, Johnson DG. E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis. Mol Cancer Res 2004;2:303-14.
-
(2004)
Mol Cancer Res
, vol.2
, pp. 303-314
-
-
Powers, J.T.1
Hong, S.2
Mayhew, C.N.3
Rogers, P.M.4
Knudsen, E.S.5
Johnson, D.G.6
-
7
-
-
33745149291
-
p53 regulates mitochondrial respiration
-
Matoba S, Kang JG, Patino WD, et al. p53 regulates mitochondrial respiration. Science 2006;312:1650-3.
-
(2006)
Science
, vol.312
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.G.2
Patino, W.D.3
-
8
-
-
17844383964
-
Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements
-
Ramanathan A, Wang C, Schreiber SL. Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements. Proc Natl Acad Sci U S A 2005;102:5992-7.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 5992-5997
-
-
Ramanathan, A.1
Wang, C.2
Schreiber, S.L.3
-
9
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003;3:721-32.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
10
-
-
0035937715
-
Regulation of glut1 mRNA by hypoxia-inducible factor-1. Interaction between H-ras and hypoxia
-
Chen C, Pore N, Behrooz A, Ismail-Beigi F, Maity A. Regulation of glut1 mRNA by hypoxia-inducible factor-1. Interaction between H-ras and hypoxia. J Biol Chem 2001;276:9519-25.
-
(2001)
J Biol Chem
, vol.276
, pp. 9519-9525
-
-
Chen, C.1
Pore, N.2
Behrooz, A.3
Ismail-Beigi, F.4
Maity, A.5
-
11
-
-
0036718539
-
Molecular basis of the VHL hereditary cancer syndrome
-
Kaelin WG, Jr. Molecular basis of the VHL hereditary cancer syndrome. Nat Rev Cancer 2002;2:673-82.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 673-682
-
-
Kaelin Jr., W.G.1
-
12
-
-
19944433653
-
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase
-
Selak MA, Armour SM, MacKenzie ED, et al. Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase. Cancer Cell 2005;7:77-85.
-
(2005)
Cancer Cell
, vol.7
, pp. 77-85
-
-
Selak, M.A.1
Armour, S.M.2
MacKenzie, E.D.3
-
13
-
-
33644622570
-
HIF-1 mediates adaptation to hypoxia by actively down-regulating mitochondrial oxygen consumption
-
Papandreou I, Cairns RA, Fontana L, Lim AL, Denko NC. HIF-1 mediates adaptation to hypoxia by actively down-regulating mitochondrial oxygen consumption. Cell Metab 2006;3:187-97.
-
(2006)
Cell Metab
, vol.3
, pp. 187-197
-
-
Papandreou, I.1
Cairns, R.A.2
Fontana, L.3
Lim, A.L.4
Denko, N.C.5
-
14
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
Kim JW, Tchernyshyov I, Semenza GL, Dang CV. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab 2006;3:177-85.
-
(2006)
Cell Metab
, vol.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
15
-
-
13444272912
-
Pyruvate dehydrogenase and pyruvate dehydrogenase kinase expression in non small cell lung cancer and tumor-associated stroma
-
Koukourakis M, Giatromanolaki A, Sivridis F, Gatter KC, Harris AL. Pyruvate dehydrogenase and pyruvate dehydrogenase kinase expression in non small cell lung cancer and tumor-associated stroma Neoplasia 2005;7:1-6.
-
(2005)
Neoplasia
, vol.7
, pp. 1-6
-
-
Koukourakis, M.1
Giatromanolaki, A.2
Sivridis, F.3
Gatter, K.C.4
Harris, A.L.5
-
16
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Nat Rev Cancer 2004;4:891-9.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
17
-
-
27844526600
-
Akt-dependent transformation: There is more to growth than just surviving
-
Plas DR, Thompson CB. Akt-dependent transformation: there is more to growth than just surviving. Oncogene 2005;24:7435-42.
-
(2005)
Oncogene
, vol.24
, pp. 7435-7442
-
-
Plas, D.R.1
Thompson, C.B.2
-
18
-
-
26644441651
-
ATP citrate lyase inhibition can suppress tumor cell growth
-
Halzivassiliou G, Zhao F, Bauer DE, et al. ATP citrate lyase inhibition can suppress tumor cell growth. Cancer Cell 2005:8:311-21.
-
(2005)
Cancer Cell
, vol.8
, pp. 311-321
-
-
Halzivassiliou, G.1
Zhao, F.2
Bauer, D.E.3
-
19
-
-
12544256565
-
Inhibition of glycolysis in cancer cells: A novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia
-
Xu RH, Pelicano H, Zhou Y, et al. Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia. Cancer Res 2005;65:613-21.
-
(2005)
Cancer Res
, vol.65
, pp. 613-621
-
-
Xu, R.H.1
Pelicano, H.2
Zhou, Y.3
-
20
-
-
11244347171
-
Glycolytic enzymes can modulate cellular life span
-
Kondoh H, Lleonart ME, Gu J, et al. Glycolytic enzymes can modulate cellular life span. Cancer Res 2005;65:177-85.
-
(2005)
Cancer Res
, vol.65
, pp. 177-185
-
-
Kondoh, H.1
Lleonart, M.E.2
Gu, J.3
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