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Volumn 2014, Issue , 2014, Pages

SOCS1 and regulation of regulatory T cells plasticity

Author keywords

[No Author keywords available]

Indexed keywords

SUPPRESSOR OF CYTOKINE SIGNALING 1; TRANSCRIPTION FACTOR FOXP3; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; SOCS1 PROTEIN, HUMAN; SUPPRESSOR OF CYTOKINE SIGNALING;

EID: 84929136427     PISSN: 23148861     EISSN: 23147156     Source Type: Journal    
DOI: 10.1155/2014/943149     Document Type: Review
Times cited : (25)

References (88)
  • 1
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • S. Hori, T. Nomura, and S. Sakaguchi, "Control of regulatory T cell development by the transcription factor Foxp3, " Science, vol. 299, no. 5609, pp. 1057-1061, 2003.
    • (2003) Science , vol.299 , Issue.5609 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 2
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • S. Sakaguchi, "Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses, " Annual Review of Immunology, vol. 22, pp. 531-562, 2004.
    • (2004) Annual Review of Immunology , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 3
    • 43949105866 scopus 로고    scopus 로고
    • Regulatory T cells and immune tolerance
    • S. Sakaguchi, T. Yamaguchi, T. Nomura, and M. Ono, "Regulatory T cells and immune tolerance, " Cell, vol. 133, no. 5, pp. 775-787, 2008.
    • (2008) Cell , vol.133 , Issue.5 , pp. 775-787
    • Sakaguchi, S.1    Yamaguchi, T.2    Nomura, T.3    Ono, M.4
  • 4
    • 67649138829 scopus 로고    scopus 로고
    • Regulatory T cells in the control of host-microorganism interactions
    • Y. Belkaid and K. Tarbell, "Regulatory T cells in the control of host-microorganism interactions, " Annual Review of Immunology, vol. 27, pp. 551-589, 2009.
    • (2009) Annual Review of Immunology , vol.27 , pp. 551-589
    • Belkaid, Y.1    Tarbell, K.2
  • 5
    • 33847125247 scopus 로고    scopus 로고
    • RegulatoryT-cell functions are subverted and converted owing to attenuated Foxp3 expression
    • Y. Y. Wanand R. A. Flavell, "RegulatoryT-cell functions are subverted and converted owing to attenuated Foxp3 expression, " Nature, vol. 445, no. 7129, pp. 766-770, 2007.
    • (2007) Nature , vol.445 , Issue.7129 , pp. 766-770
    • Wanand, Y.Y.1    Flavell, A.R.2
  • 6
    • 0035167967 scopus 로고    scopus 로고
    • The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
    • C. L. Bennett, J. Christie, F. Ramsdell, et al., "The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3, " Nature Genetics, vol. 27, no. 1, pp. 20-21, 2001.
    • (2001) Nature Genetics , vol.27 , Issue.1 , pp. 20-21
    • Bennett, C.L.1    Christie, J.2    Ramsdell, F.3
  • 7
    • 0035162560 scopus 로고    scopus 로고
    • Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
    • M. E. Brunkow, E. W. Jeffery, K. A. Hjerrild, et al., "Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse, " Nature Genetics, vol. 27, no. 1, pp. 68-73, 2001.
    • (2001) Nature Genetics , vol.27 , Issue.1 , pp. 68-73
    • Brunkow, M.E.1    Jeffery, E.W.2    Hjerrild, K.A.3
  • 8
    • 82155170631 scopus 로고    scopus 로고
    • Thymic and peripheral differentiation of regulatory T Cells
    • H. Lee, J. L. Bautista, and C. Hsieh, "Thymic and peripheral differentiation of regulatory T Cells, " Advances in Immunology, vol. 112, pp. 25-71, 2011.
    • (2011) Advances in Immunology , vol.112 , pp. 25-71
    • Lee, H.1    Bautista, J.L.2    Hsieh, C.3
  • 9
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25-naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
    • W. Chen, W. Jin, N. Hardegen, et al., "Conversion of peripheral CD4+CD25-naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3, " The Journal of Experimental Medicine, vol. 198, no. 12, pp. 1875-1886, 2003.
    • (2003) The Journal of Experimental Medicine , vol.198 , Issue.12 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3
  • 10
    • 79958021546 scopus 로고    scopus 로고
    • IL-2 controls the stability of Foxp3 expression in TGF-β-induced Foxp3+ T cells in vivo
    • Q. Chen, Y. C. Kim, A. Laurence, G. A. Punkosdy, and E. M. Shevach, "IL-2 controls the stability of Foxp3 expression in TGF-β-induced Foxp3+ T cells in vivo, " Journal of Immunology, vol. 186, no. 11, pp. 6329-6337, 2011.
    • (2011) Journal of Immunology , vol.186 , Issue.11 , pp. 6329-6337
    • Chen, Q.1    Kim, Y.C.2    Laurence, A.3    Punkosdy, G.A.4    Shevach, E.M.5
  • 12
    • 69049107358 scopus 로고    scopus 로고
    • Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
    • X. Zhou, S. L. Bailey-Bucktrout, L. T. Jeker, et al., "Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo, " Nature Immunology, vol. 10, no. 9, pp. 1000-1007, 2009.
    • (2009) Nature Immunology , vol.10 , Issue.9 , pp. 1000-1007
    • Zhou, X.1    Bailey-Bucktrout, S.L.2    Jeker, L.T.3
  • 13
    • 84891838421 scopus 로고    scopus 로고
    • Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis
    • K. Noriko, O. Kazuo, S. Shinichiro, et al., "Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis, " Nature Medicine, vol. 20, no. 1, pp. 62-68, 2014.
    • (2014) Nature Medicine , vol.20 , Issue.1 , pp. 62-68
    • Noriko, K.1    Kazuo, O.2    Shinichiro, S.3
  • 15
  • 16
    • 4143066714 scopus 로고    scopus 로고
    • Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors
    • C. Hsieh, Y. Liang, A. J. Tyznik, S. G. Self, D. Liggitt, and A. Y. Rudensky, "Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors, " Immunity, vol. 21, no. 2, pp. 267-277, 2004.
    • (2004) Immunity , vol.21 , Issue.2 , pp. 267-277
    • Hsieh, C.1    Liang, Y.2    Tyznik, A.J.3    Self, S.G.4    Liggitt, D.5    Rudensky, A.Y.6
  • 17
    • 0033682056 scopus 로고    scopus 로고
    • B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
    • B. Salomon, D. J. Lenschow, L. Rhee, et al., "B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes, " Immunity, vol. 12, no. 4, pp. 431-440, 2000.
    • (2000) Immunity , vol.12 , Issue.4 , pp. 431-440
    • Salomon, B.1    Lenschow, D.J.2    Rhee, L.3
  • 18
    • 13944260538 scopus 로고    scopus 로고
    • CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
    • X. Tai, M. Cowan, L. Feigenbaum, and A. Singer, "CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2, " Nature Immunology, vol. 6, no. 2, pp. 152-162, 2005.
    • (2005) Nature Immunology , vol.6 , Issue.2 , pp. 152-162
    • Tai, X.1    Cowan, M.2    Feigenbaum, L.3    Singer, A.4
  • 20
    • 41149113441 scopus 로고    scopus 로고
    • The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells
    • S. Haxhinasto, D. Mathis, and C. Benoist, "The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells, " The Journal of Experimental Medicine, vol. 205, no. 3, pp. 565-574, 2008.
    • (2008) The Journal of Experimental Medicine , vol.205 , Issue.3 , pp. 565-574
    • Haxhinasto, S.1    Mathis, D.2    Benoist, C.3
  • 21
    • 84886947397 scopus 로고    scopus 로고
    • Transcriptional control of regulatory T cell development and function
    • C. T. Luo and M. O. Li, "Transcriptional control of regulatory T cell development and function, " Trends in Immunology, vol. 34, no. 11, pp. 531-539, 2013.
    • (2013) Trends in Immunology , vol.34 , Issue.11 , pp. 531-539
    • Luo, C.T.1    Li, M.O.2
  • 22
    • 33644844341 scopus 로고    scopus 로고
    • Molecularmechanisms underlying FOXP3 induction in human T cells
    • P. Mantel, N. Ouaked, B. Ruckert, et al., "Molecularmechanisms underlying FOXP3 induction in human T cells, " Journal of Immunology, vol. 176, no. 6, pp. 3593-3602, 2006.
    • (2006) Journal of Immunology , vol.176 , Issue.6 , pp. 3593-3602
    • Mantel, P.1    Ouaked, N.2    Ruckert, B.3
  • 23
    • 79953769170 scopus 로고    scopus 로고
    • The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells
    • article 269
    • T. Sekiya, I. Kashiwagi, N. Inoue, et al., "The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells, " Nature Communications, vol. 2, no. 1, article 269, 2011.
    • (2011) Nature Communications , vol.2 , Issue.1
    • Sekiya, T.1    Kashiwagi, I.2    Inoue, N.3
  • 24
    • 85027932757 scopus 로고    scopus 로고
    • Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis
    • T. Sekiya, I. Kashiwagi, R. Yoshida, et al., "Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis, " Nature Immunology, vol. 14, no. 3, pp. 230-237, 2013.
    • (2013) Nature Immunology , vol.14 , Issue.3 , pp. 230-237
    • Sekiya, T.1    Kashiwagi, I.2    Yoshida, R.3
  • 25
    • 38349095578 scopus 로고    scopus 로고
    • Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer
    • Y. Tone, K. Furuuchi, Y. Kojima, M. L. Tykocinski, M. I. Greene, and M. Tone, "Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer, "Nature Immunology, vol. 9, no. 2, pp. 194-202, 2008.
    • (2008) Nature Immunology , vol.9 , Issue.2 , pp. 194-202
    • Tone, Y.1    Furuuchi, K.2    Kojima, Y.3    Tykocinski, M.L.4    Greene, M.I.5    Tone, M.6
  • 26
    • 47249085266 scopus 로고    scopus 로고
    • STAT6 inhibits TGF-β1-mediated Foxp3 induction through direct binding to the Foxp3 promoter, which is reverted by retinoic acid receptor
    • H. Takaki, K. Ichiyama, K. Koga, et al., "STAT6 inhibits TGF-β1-mediated Foxp3 induction through direct binding to the Foxp3 promoter, which is reverted by retinoic acid receptor, " The Journal of Biological Chemistry, vol. 283, no. 22, pp. 14955-14962, 2008.
    • (2008) The Journal of Biological Chemistry , vol.283 , Issue.22 , pp. 14955-14962
    • Takaki, H.1    Ichiyama, K.2    Koga, K.3
  • 27
    • 76749133610 scopus 로고    scopus 로고
    • Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
    • Y. Zheng, S. Josefowicz, A. Chaudhry, X. P. Peng, K. Forbush, and A. Y. Rudensky, "Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate, " Nature, vol. 463, no. 7282, pp. 808-812, 2010.
    • (2010) Nature , vol.463 , Issue.7282 , pp. 808-812
    • Zheng, Y.1    Josefowicz, S.2    Chaudhry, A.3    Peng, X.P.4    Forbush, K.5    Rudensky, A.Y.6
  • 28
    • 77955498891 scopus 로고    scopus 로고
    • Smad2 and Smad3 are redundantly essential for the TGF-β-mediated regulation of regulatory T plasticity and Th1 development
    • T. Takimoto, Y. Wakabayashi, T. Sekiya, et al., "Smad2 and Smad3 are redundantly essential for the TGF-β-mediated regulation of regulatory T plasticity and Th1 development, " Journal of Immunology, vol. 185, no. 2, pp. 842-855, 2010.
    • (2010) Journal of Immunology , vol.185 , Issue.2 , pp. 842-855
    • Takimoto, T.1    Wakabayashi, Y.2    Sekiya, T.3
  • 29
    • 34447265236 scopus 로고    scopus 로고
    • CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: A role for DNA methylation
    • H.-P. Kim and W. J. Leonard, "CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation, " The Journal of Experimental Medicine, vol. 204, no. 7, pp. 1543-1551, 2007.
    • (2007) The Journal of Experimental Medicine , vol.204 , Issue.7 , pp. 1543-1551
    • Kim, H.-P.1    Leonard, W.J.2
  • 30
    • 33845935950 scopus 로고    scopus 로고
    • IL-2 receptor β-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells
    • M. A. Burchill, J. Yang, C. Vogtenhuber, B. R. Blazar, and M. A. Farrar, "IL-2 receptor β-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells, " Journal of Immunology, vol. 178, no. 1, pp. 280-290, 2007.
    • (2007) Journal of Immunology , vol.178 , Issue.1 , pp. 280-290
    • Burchill, M.A.1    Yang, J.2    Vogtenhuber, C.3    Blazar, B.R.4    Farrar, M.A.5
  • 31
    • 70449407848 scopus 로고    scopus 로고
    • Alloantigen-specific de novo-induced Foxp3+ Treg revert in vivo and do not protect from experimental GVHD
    • C. Koenecke, N. Czeloth, A. Bubke, et al., "Alloantigen-specific de novo-induced Foxp3+ Treg revert in vivo and do not protect from experimental GVHD, " European Journal of Immunology, vol. 39, no. 11, pp. 3091-3096, 2009.
    • (2009) European Journal of Immunology , vol.39 , Issue.11 , pp. 3091-3096
    • Koenecke, C.1    Czeloth, N.2    Bubke, A.3
  • 32
    • 33846980131 scopus 로고    scopus 로고
    • Epigenetic control of the foxp3 locus in regulatory T cells
    • article e38
    • S. Floess, J. Freyer, C. Siewert, et al., "Epigenetic control of the foxp3 locus in regulatory T cells, " PLoS Biology, vol. 5, no. 2, article e38, 2007.
    • (2007) PLoS Biology , vol.5 , Issue.2
    • Floess, S.1    Freyer, J.2    Siewert, C.3
  • 33
    • 79958021546 scopus 로고    scopus 로고
    • IL-2 controls the stability of Foxp3 expression in TGF-β-induced Foxp3+ T cells in vivo
    • Q. Chen, Y. C. Kim, A. Laurence, G. A. Punkosdy, and E. M. Shevach, "IL-2 controls the stability of Foxp3 expression in TGF-β-induced Foxp3+ T cells in vivo, " Journal of Immunology, vol. 186, no. 11, pp. 6329-6337, 2011.
    • (2011) Journal of Immunology , vol.186 , Issue.11 , pp. 6329-6337
    • Chen, Q.1    Kim, Y.C.2    Laurence, A.3    Punkosdy, G.A.4    Shevach, E.M.5
  • 34
    • 84875498856 scopus 로고    scopus 로고
    • Development and maintenance of regulatory T cells
    • N. Ohkura, Y. Kitagawa, and S. Sakaguchi, "Development and maintenance of regulatory T cells, " Immunity, vol. 38, no. 3, pp. 414-423, 2013.
    • (2013) Immunity , vol.38 , Issue.3 , pp. 414-423
    • Ohkura, N.1    Kitagawa, Y.2    Sakaguchi, S.3
  • 35
    • 84866533054 scopus 로고    scopus 로고
    • A multiply redundant genetic switch "locks in" the transcriptional signature of regulatory T cells
    • W. Fu, A. Ergun, T. Lu, et al., "A multiply redundant genetic switch "locks in" the transcriptional signature of regulatory T cells, " Nature Immunology, vol. 13, no. 10, pp. 972-980, 2012.
    • (2012) Nature Immunology , vol.13 , Issue.10 , pp. 972-980
    • Fu, W.1    Ergun, A.2    Lu, T.3
  • 36
    • 84869148187 scopus 로고    scopus 로고
    • TCell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development
    • N. Ohkura, M. Hamaguchi, H. Morikawa, et al., "TCell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development, " Immunity, vol. 37, no. 5, pp. 785-799, 2012.
    • (2012) Immunity , vol.37 , Issue.5 , pp. 785-799
    • Ohkura, N.1    Hamaguchi, M.2    Morikawa, H.3
  • 37
    • 67650090496 scopus 로고    scopus 로고
    • Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity
    • C. Schmidl, M. Klug, T. J. Boeld, et al., "Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity, " Genome Research, vol. 19, no. 7, pp. 1165-1174, 2009.
    • (2009) Genome Research , vol.19 , Issue.7 , pp. 1165-1174
    • Schmidl, C.1    Klug, M.2    Boeld, T.J.3
  • 38
    • 84869148187 scopus 로고    scopus 로고
    • T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development
    • N. Ohkura, M. Hamaguchi, H. Morikawa, et al., "T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development, " Immunity, vol. 37, no. 5, pp. 785-799, 2012.
    • (2012) Immunity , vol.37 , Issue.5 , pp. 785-799
    • Ohkura, N.1    Hamaguchi, M.2    Morikawa, H.3
  • 39
    • 34047174849 scopus 로고    scopus 로고
    • Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production
    • S. E. Allan, S. Q. Crome, N. K. Crellin, et al., "Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production, " International Immunology, vol. 19, no. 4, pp. 345-354, 2007.
    • (2007) International Immunology , vol.19 , Issue.4 , pp. 345-354
    • Allan, S.E.1    Crome, S.Q.2    Crellin, N.K.3
  • 41
    • 84857416489 scopus 로고    scopus 로고
    • Plasticity of Foxp3 + T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells
    • T. Miyao, S. Floess, R. Setoguchi, et al., "Plasticity of Foxp3 + T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells, " Immunity, vol. 36, no. 2, pp. 262-275, 2012.
    • (2012) Immunity , vol.36 , Issue.2 , pp. 262-275
    • Miyao, T.1    Floess, S.2    Setoguchi, R.3
  • 42
    • 77955859925 scopus 로고    scopus 로고
    • Regulatory T-cell stability and plasticity in mucosal and systemic immune systems
    • M. Murai, P. Krause, H. Cheroutre, and M. Kronenberg, "Regulatory T-cell stability and plasticity in mucosal and systemic immune systems, " Mucosal Immunology, vol. 3, no. 5, pp. 443-449, 2010.
    • (2010) Mucosal Immunology , vol.3 , Issue.5 , pp. 443-449
    • Murai, M.1    Krause, P.2    Cheroutre, H.3    Kronenberg, M.4
  • 43
    • 77957371028 scopus 로고    scopus 로고
    • Stability of the regulatory T cell lineage in vivo
    • Y. P. Rubtsov, R. E. Niec, S. Josefowicz, et al., "Stability of the regulatory T cell lineage in vivo, " Science, vol. 329, no. 5999, pp. 1667-1671, 2010.
    • (2010) Science , vol.329 , Issue.5999 , pp. 1667-1671
    • Rubtsov, Y.P.1    Niec, R.E.2    Josefowicz, S.3
  • 44
    • 77749245810 scopus 로고    scopus 로고
    • C-Rel: A pioneer in directing regulatory T-cell lineage commitment?
    • S. Hori, "c-Rel: a pioneer in directing regulatory T-cell lineage commitment?" European Journal of Immunology, vol. 40, no. 3, pp. 664-667, 2010.
    • (2010) European Journal of Immunology , vol.40 , Issue.3 , pp. 664-667
    • Hori, S.1
  • 45
    • 34447265236 scopus 로고    scopus 로고
    • CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: A role for DNA methylation
    • H. Kim and W. J. Leonard, "CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation, " Journal of Experimental Medicine, vol. 204, no. 7, pp. 1543-1551, 2007.
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.7 , pp. 1543-1551
    • Kim, H.1    Leonard, W.J.2
  • 46
    • 77957724587 scopus 로고    scopus 로고
    • The Ets-1 transcription factor controls the development and function of natural regulatory T cells
    • E. Mouly, K. Chemin, H. V. Nguyen, et al., "The Ets-1 transcription factor controls the development and function of natural regulatory T cells, " Journal of Experimental Medicine, vol. 207, no. 10, pp. 2113-2125, 2010.
    • (2010) Journal of Experimental Medicine , vol.207 , Issue.10 , pp. 2113-2125
    • Mouly, E.1    Chemin, K.2    Nguyen, H.V.3
  • 48
    • 84866548843 scopus 로고    scopus 로고
    • Transcription factor Foxp3 and its protein partners form a complex regulatory network
    • D. Rudra, P. Deroos, A. Chaudhry, et al., "Transcription factor Foxp3 and its protein partners form a complex regulatory network, " Nature Immunology, vol. 13, no. 10, pp. 1010-1019, 2012.
    • (2012) Nature Immunology , vol.13 , Issue.10 , pp. 1010-1019
    • Rudra, D.1    Deroos, P.2    Chaudhry, A.3
  • 49
    • 33746228122 scopus 로고    scopus 로고
    • FOXP3 controls regulatory T cell function through cooperation with NFAT
    • Y. Wu, M. Borde, V. Heissmeyer, et al., "FOXP3 controls regulatory T cell function through cooperation with NFAT, " Cell, vol. 126, no. 2, pp. 375-387, 2006.
    • (2006) Cell , vol.126 , Issue.2 , pp. 375-387
    • Wu, Y.1    Borde, M.2    Heissmeyer, V.3
  • 50
    • 34247215187 scopus 로고    scopus 로고
    • Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
    • M. Ono, H. Yaguchi, N. Ohkura, et al., "Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1, " Nature, vol. 446, no. 7136, pp. 685-689, 2007.
    • (2007) Nature , vol.446 , Issue.7136 , pp. 685-689
    • Ono, M.1    Yaguchi, H.2    Ohkura, N.3
  • 51
    • 70349741295 scopus 로고    scopus 로고
    • Indispensable role of the Runx1-Cbftranscription complex for in vivo-suppressive function of FoxP3+ regulatory T cells
    • A. Kitoh, M. Ono, Y. Naoe, et al., "Indispensable role of the Runx1-Cbftranscription complex for in vivo-suppressive function of FoxP3+ regulatory T cells, " Immunity, vol. 31, no. 4, pp. 609-620, 2009.
    • (2009) Immunity , vol.31 , Issue.4 , pp. 609-620
    • Kitoh, A.1    Ono, M.2    Naoe, Y.3
  • 52
    • 58849118836 scopus 로고    scopus 로고
    • Epigenetic control of FOXP3 expression: The key to a stable regulatory T-cell lineage?
    • J. Huehn, J. K. Polansky, and A. Hamann, "Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?" Nature Reviews Immunology, vol. 9, no. 2, pp. 83-89, 2009.
    • (2009) Nature Reviews Immunology , vol.9 , Issue.2 , pp. 83-89
    • Huehn, J.1    Polansky, J.K.2    Hamann, A.3
  • 53
    • 34249799285 scopus 로고    scopus 로고
    • Cutting edge: Regulatory T cells induce CD4+CD25 -Foxp3-T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-β
    • L. Xu, A. Kitani, I. Fuss, and W. Strober, "Cutting edge: Regulatory T cells induce CD4+CD25 -Foxp3-T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-β, " Journal of Immunology, vol. 178, no. 11, pp. 6725-6729, 2007.
    • (2007) Journal of Immunology , vol.178 , Issue.11 , pp. 6725-6729
    • Xu, L.1    Kitani, A.2    Fuss, I.3    Strober, W.4
  • 54
    • 46749138596 scopus 로고    scopus 로고
    • Molecular antagonism and plasticity of regulatory and inflammatory T cell programs
    • X. O. Yang, R. Nurieva, G. J. Martinez, et al., "Molecular antagonism and plasticity of regulatory and inflammatory T cell programs, " Immunity, vol. 29, no. 1, pp. 44-56, 2008.
    • (2008) Immunity , vol.29 , Issue.1 , pp. 44-56
    • Yang, X.O.1    Nurieva, R.2    Martinez, G.J.3
  • 55
    • 70449532980 scopus 로고    scopus 로고
    • Decrease of Foxp3+ treg cell number and acquisition of effector cell phenotype during lethal infection
    • G. Oldenhove, N. Bouladoux, E. A. Wohlfert, et al., "Decrease of Foxp3+ treg cell number and acquisition of effector cell phenotype during lethal infection, " Immunity, vol. 31, no. 5, pp. 772-786, 2009.
    • (2009) Immunity , vol.31 , Issue.5 , pp. 772-786
    • Oldenhove, G.1    Bouladoux, N.2    Wohlfert, E.A.3
  • 56
    • 84860187314 scopus 로고    scopus 로고
    • Inflammationdriven reprogramming of CD4+ foxp3+ regulatory T cells into pathogenicTh1/Th17t effectors is abrogated bymTORinhibition in vivo
    • Article ID e35572
    • E. Yurchenko, M. T. Shio, T. C. Huang, et al., "Inflammationdriven reprogramming of CD4+ foxp3+ regulatory T cells into pathogenicTh1/Th17t effectors is abrogated bymTORinhibition in vivo, " PLoS ONE, vol. 7, no. 4, Article ID e35572, 2012.
    • (2012) PLoS ONE , vol.7 , Issue.4
    • Yurchenko, E.1    Shio, M.T.2    Huang, T.C.3
  • 57
    • 80555154007 scopus 로고    scopus 로고
    • SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-β and IL-17A production
    • R. Takahashi, S. Nishimoto, G. Muto, et al., "SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-β and IL-17A production, " Journal of Experimental Medicine, vol. 208, no. 10, pp. 2055-2067, 2011.
    • (2011) Journal of Experimental Medicine , vol.208 , Issue.10 , pp. 2055-2067
    • Takahashi, R.1    Nishimoto, S.2    Muto, G.3
  • 58
    • 79958134797 scopus 로고    scopus 로고
    • Identification of T helper type 1-like, Foxp3+ regulatory T cells in human autoimmune disease
    • M. Dominguez-Villar, C. M. Baecher-Allan, and D. A. Hafler, "Identification of T helper type 1-"like, Foxp3+ regulatory T cells in human autoimmune disease, " Nature Medicine, vol. 17, no. 6, pp. 673-675, 2011.
    • (2011) Nature Medicine , vol.17 , Issue.6 , pp. 673-675
    • Dominguez-Villar, M.1    Baecher-Allan, C.M.2    Hafler, D.A.3
  • 59
    • 84865367294 scopus 로고    scopus 로고
    • STAT3 transcription factor promotes instability of nTreg cells and limits generation of iTreg cells during acute murine graft-versus-host disease
    • A. Laurence, S. Amarnath, J. Mariotti, et al., "STAT3 transcription factor promotes instability of nTreg cells and limits generation of iTreg cells during acute murine graft-versus-host disease, " Immunity, vol. 37, no. 2, pp. 209-222, 2012.
    • (2012) Immunity , vol.37 , Issue.2 , pp. 209-222
    • Laurence, A.1    Amarnath, S.2    Mariotti, J.3
  • 60
    • 79955028001 scopus 로고    scopus 로고
    • Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes
    • S. A. McClymont, A. L. Putnam, M. R. Lee, et al., "Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes, " Journal of Immunology, vol. 186, no. 7, pp. 3918-3926, 2011.
    • (2011) Journal of Immunology , vol.186 , Issue.7 , pp. 3918-3926
    • McClymont, S.A.1    Putnam, A.L.2    Lee, M.R.3
  • 61
    • 78650124721 scopus 로고    scopus 로고
    • Reprogrammed Foxp3+ regulatory T cells provide essential help to support crosspresentation and CD8+ T cell priming in naive mice
    • M. D. Sharma, D. Hou, B. Baban, et al., "Reprogrammed Foxp3+ regulatory T cells provide essential help to support crosspresentation and CD8+ T cell priming in naive mice, " Immunity, vol. 33, no. 6, pp. 942-954, 2010.
    • (2010) Immunity , vol.33 , Issue.6 , pp. 942-954
    • Sharma, M.D.1    Hou, D.2    Baban, B.3
  • 62
    • 84887512828 scopus 로고    scopus 로고
    • Selfantigen-driven activation induces instability of regulatory t cells during an inflammatory autoimmune response
    • S. Bailey-Bucktrout, M. Martinez-Llordella, X. Zhou, et al., "Selfantigen-driven activation induces instability of regulatory t cells during an inflammatory autoimmune response, " Immunity, vol. 39, no. 5, pp. 949-962, 2013.
    • (2013) Immunity , vol.39 , Issue.5 , pp. 949-962
    • Bailey-Bucktrout, S.1    Martinez-Llordella, M.2    Zhou, X.3
  • 63
    • 84875153425 scopus 로고    scopus 로고
    • Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-in rheumatoid arthritis
    • H. Nie, Y. Zheng, R. Li, et al., "Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-in rheumatoid arthritis, " Nature Medicine, vol. 19, no. 3, pp. 322-328, 2013.
    • (2013) Nature Medicine , vol.19 , Issue.3 , pp. 322-328
    • Nie, H.1    Zheng, Y.2    Li, R.3
  • 64
    • 78751696183 scopus 로고    scopus 로고
    • Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: Safety profile and detection kinetics
    • C. G. Brunstein, J. S. Miller, Q. Cao, et al., "Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics, " Blood, vol. 117, no. 3, pp. 1061-1070, 2011.
    • (2011) Blood , vol.117 , Issue.3 , pp. 1061-1070
    • Brunstein, C.G.1    Miller, J.S.2    Cao, Q.3
  • 65
    • 84887512828 scopus 로고    scopus 로고
    • Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response
    • S. L. Bailey-Bucktrout, M. Martinez-Llordella, X. Zhou, et al., "Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response, " Immunity, vol. 39, no. 5, pp. 949-962, 2013.
    • (2013) Immunity , vol.39 , Issue.5 , pp. 949-962
    • Bailey-Bucktrout, S.L.1    Martinez-Llordella, M.2    Zhou, X.3
  • 66
    • 84884161974 scopus 로고    scopus 로고
    • TRAF6 is essential for maintenance of regulatory T cells that suppress Th2 type autoimmunity
    • Article IDe74639
    • G. Muto, H. Kotani, T. Kondo, et al., "TRAF6 is essential for maintenance of regulatory T cells that suppress Th2 type autoimmunity, " PLoS ONE, vol. 8, no. 9, Article IDe74639, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.9
    • Muto, G.1    Kotani, H.2    Kondo, T.3
  • 67
    • 84883767441 scopus 로고    scopus 로고
    • Inhibition of p300 impairs Foxp3+ T regulatory cell function and promotes antitumor immunity
    • Y. Liu, L. Wang, J. Predina, et al., "Inhibition of p300 impairs Foxp3+ T regulatory cell function and promotes antitumor immunity, " Nature Medicine, vol. 19, no. 9, pp. 1173-1177, 2013.
    • (2013) Nature Medicine , vol.19 , Issue.9 , pp. 1173-1177
    • Liu, Y.1    Wang, L.2    Predina, J.3
  • 68
    • 84869872964 scopus 로고    scopus 로고
    • Novel Foxo1-dependent transcriptional programs control T reg cell function
    • W. Ouyang, W. Liao, C. T. Luo, et al., "Novel Foxo1-dependent transcriptional programs control T reg cell function, " Nature, vol. 491, no. 7425, pp. 554-559, 2012.
    • (2012) Nature , vol.491 , Issue.7425 , pp. 554-559
    • Ouyang, W.1    Liao, W.2    Luo, C.T.3
  • 69
    • 84895751735 scopus 로고    scopus 로고
    • PARP-1 controls immunosuppressive function of regulatory T cells by destabilizing Foxp3
    • Article ID e71590
    • P. Zhang, T. Maruyama, J. E. Konkel, et al., "PARP-1 controls immunosuppressive function of regulatory T cells by destabilizing Foxp3, " PloS ONE, vol. 8, no. 8, Article ID e71590, 2013.
    • (2013) PloS ONE , vol.8 , Issue.8
    • Zhang, P.1    Maruyama, T.2    Konkel, J.E.3
  • 70
    • 84879087114 scopus 로고    scopus 로고
    • Cutting edge: Receptors for C3a and C5a modulate stability of alloantigen-reactive induced regulatory T cells
    • W. van der Touw, P. Cravedi, W. Kwan, E. Paz-Artal, M. Merad, and P. S. Heeger, "Cutting edge: receptors for C3a and C5a modulate stability of alloantigen-reactive induced regulatory T cells, " Journal of Immunology, vol. 190, no. 12, pp. 5921-5925, 2013.
    • (2013) Journal of Immunology , vol.190 , Issue.12 , pp. 5921-5925
    • Touw Der W.Van1    Cravedi, P.2    Kwan, W.3    Paz-Artal, E.4    Merad, M.5    Heeger, P.S.6
  • 71
    • 84863229506 scopus 로고    scopus 로고
    • Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells
    • H. Kwon, H. W. Lim, J. Wu, M. Schnolzer, E. Verdin, and M. Ott, "Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells, " Journal of Immunology, vol. 188, no. 6, pp. 2712-2721, 2012.
    • (2012) Journal of Immunology , vol.188 , Issue.6 , pp. 2712-2721
    • Kwon, H.1    Lim, H.W.2    Wu, J.3    Schnolzer, M.4    Verdin, E.5    Ott, M.6
  • 72
    • 80555154007 scopus 로고    scopus 로고
    • SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-β and IL-17A production
    • R. Takahashi, S. Nishimoto, G. Muto, et al., "SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-β and IL-17A production, "TheJournal of Experimental Medicine, vol. 208, no. 10, pp. 2055-2067, 2011.
    • (2011) TheJournal of Experimental Medicine , vol.208 , Issue.10 , pp. 2055-2067
    • Takahashi, R.1    Nishimoto, S.2    Muto, G.3
  • 73
    • 58149268107 scopus 로고    scopus 로고
    • Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein
    • L. Lu, T. Thai, D. P. Calado, et al., "Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein, " Immunity, vol. 30, no. 1, pp. 80-91, 2009.
    • (2009) Immunity , vol.30 , Issue.1 , pp. 80-91
    • Lu, L.1    Thai, T.2    Calado, D.P.3
  • 74
    • 77956632634 scopus 로고    scopus 로고
    • Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses
    • L. Lu, M. P. Boldin, A. Chaudhry, et al., "Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses, " Cell, vol. 142, no. 6, pp. 914-929, 2010.
    • (2010) Cell , vol.142 , Issue.6 , pp. 914-929
    • Lu, L.1    Boldin, M.P.2    Chaudhry, A.3
  • 75
    • 34249660614 scopus 로고    scopus 로고
    • SOCS proteins, cytokine signalling and immune regulation
    • A. Yoshimura, T. Naka, and M. Kubo, "SOCS proteins, cytokine signalling and immune regulation, " Nature Reviews Immunology, vol. 7, no. 6, pp. 454-465, 2007.
    • (2007) Nature Reviews Immunology , vol.7 , Issue.6 , pp. 454-465
    • Yoshimura, A.1    Naka, T.2    Kubo, M.3
  • 76
    • 84859900589 scopus 로고    scopus 로고
    • Ubc13maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells
    • J. Chang, Y. Xiao, H. Hu, et al., "Ubc13maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells, " Nature Immunology, vol. 13, no. 5, pp. 481-490, 2012.
    • (2012) Nature Immunology , vol.13 , Issue.5 , pp. 481-490
    • Chang, J.1    Xiao, Y.2    Hu, H.3
  • 77
    • 44849115688 scopus 로고    scopus 로고
    • Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-β on STAT3 and Smads
    • K. Tanaka, K. Ichiyama, M. Hashimoto, et al., "Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-β on STAT3 and Smads, " Journal of Immunology, vol. 180, no. 6, pp. 3746-3756, 2008.
    • (2008) Journal of Immunology , vol.180 , Issue.6 , pp. 3746-3756
    • Tanaka, K.1    Ichiyama, K.2    Hashimoto, M.3
  • 78
    • 84867901322 scopus 로고    scopus 로고
    • Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo
    • M. Yadav, C. Louvet, D. Davini, et al., "Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo, " Journal of Experimental Medicine, vol. 209, no. 10, pp. 1713-1722, 2012.
    • (2012) Journal of Experimental Medicine , vol.209 , Issue.10 , pp. 1713-1722
    • Yadav, M.1    Louvet, C.2    Davini, D.3
  • 79
    • 84867899425 scopus 로고    scopus 로고
    • Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosagenerated induced Foxp3+ T reg cells
    • J. M. Weiss, A. M. Bilate, M. Gobert, et al., "Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosagenerated induced Foxp3+ T reg cells, " The Journal of Experimental Medicine, vol. 209, no. 10, pp. 1723-1742, 2012.
    • (2012) The Journal of Experimental Medicine , vol.209 , Issue.10 , pp. 1723-1742
    • Weiss, J.M.1    Bilate, A.M.2    Gobert, M.3
  • 80
    • 27344438941 scopus 로고    scopus 로고
    • Immune cells and cytokines in systemic lupus erythematosus: An update
    • V. C. Kyttaris, Y. Juang, and G. C. Tsokos, "Immune cells and cytokines in systemic lupus erythematosus: an update," Current Opinion in Rheumatology, vol. 17, no. 5, pp. 518522, 2005.
    • (2005) Current Opinion in Rheumatology , vol.17 , Issue.5 , pp. 518-522
    • Kyttaris, V.C.1    Juang, Y.2    Tsokos, G.C.3
  • 81
    • 23244463009 scopus 로고    scopus 로고
    • Failure of CD25+ T cells from lupus-prone mice to suppress lupus glomerulonephritis and sialoadenitis
    • H. Bagavant and K. S. K. Tung, "Failure of CD25+ T cells from lupus-prone mice to suppress lupus glomerulonephritis and sialoadenitis, " Journal of Immunology, vol. 175, no. 2, pp. 944-950, 2005.
    • (2005) Journal of Immunology , vol.175 , Issue.2 , pp. 944-950
    • Bagavant, H.1    Tung, K.S.K.2
  • 82
    • 62449202866 scopus 로고    scopus 로고
    • Preferential generation of follicular B helper T cells from Foxp3 + T cells in gut Peyers patches
    • M. Tsuji, N. Komatsu, S. Kawamoto, et al., "Preferential generation of follicular B helper T cells from Foxp3 + T cells in gut Peyers patches, " Science, vol. 323, no. 5920, pp. 1488-1492, 2009.
    • (2009) Science , vol.323 , Issue.5920 , pp. 1488-1492
    • Tsuji, M.1    Komatsu, N.2    Kawamoto, S.3
  • 83
    • 79961158055 scopus 로고    scopus 로고
    • Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
    • Y. Chung, S. Tanaka, F. Chu, et al., "Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions, " Nature Medicine, vol. 17, no. 8, pp. 983-988, 2011.
    • (2011) Nature Medicine , vol.17 , Issue.8 , pp. 983-988
    • Chung, Y.1    Tanaka, S.2    Chu, F.3
  • 84
    • 79961151137 scopus 로고    scopus 로고
    • Foxp3+ follicular regulatory T cells control the germinal center response
    • M. A. Linterman, W. Pierson, S. K. Lee, et al., "Foxp3+ follicular regulatory T cells control the germinal center response, " Nature Medicine, vol. 17, no. 8, pp. 975-982, 2011.
    • (2011) Nature Medicine , vol.17 , Issue.8 , pp. 975-982
    • Linterman, M.A.1    Pierson, W.2    Lee, S.K.3
  • 85
    • 80555133319 scopus 로고    scopus 로고
    • Regulation of the germinal center reaction by Foxp3+ follicular regulatory T cells
    • I. Wollenberg, A. Agua-Doce, A. Hernandez, et al., "Regulation of the germinal center reaction by Foxp3+ follicular regulatory T cells, " Journal of Immunology, vol. 187, no. 9, pp. 4553-4560, 2011.
    • (2011) Journal of Immunology , vol.187 , Issue.9 , pp. 4553-4560
    • Wollenberg, I.1    Agua-Doce, A.2    Hernandez, A.3
  • 86
    • 84892544628 scopus 로고    scopus 로고
    • TRAF3 regulates the effector function of regulatory T cells and humoral immune responses
    • J.-H. Chang, H. Hu, J. Jin, et al., "TRAF3 regulates the effector function of regulatory T cells and humoral immune responses, " The Journal of ExperimentalMedicine, vol. 211, no. 1, pp. 137-151, 2014.
    • (2014) The Journal of ExperimentalMedicine , vol.211 , Issue.1 , pp. 137-151
    • Chang, J.-H.1    Hu, H.2    Jin, J.3
  • 87
    • 65449149735 scopus 로고    scopus 로고
    • Altered homeostasis of CD4+ FoxP3+ regulatory T-cell subpopulations in systemic lupus erythematosus
    • J. Suen, H. Li, Y. Jong, B. Chiang, and J. Yen, "Altered homeostasis of CD4+ FoxP3+ regulatory T-cell subpopulations in systemic lupus erythematosus, " Immunology, vol. 127, no. 2, pp. 196-205, 2009.
    • (2009) Immunology , vol.127 , Issue.2 , pp. 196-205
    • Suen, J.1    Li, H.2    Jong, Y.3    Chiang, B.4    Yen, J.5
  • 88
    • 40549128298 scopus 로고    scopus 로고
    • Dysfunctional CD4+, CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-producing antigen-presenting cells
    • B. Yan, S. Ye, G. Chen, M. Kuang, N. Shen, and S. Chen, "Dysfunctional CD4+, CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-producing antigen-presenting cells, " Arthritis and Rheumatism, vol. 58, no. 3, pp. 801-812, 2008.
    • (2008) Arthritis and Rheumatism , vol.58 , Issue.3 , pp. 801-812
    • Yan, B.1    Ye, S.2    Chen, G.3    Kuang, M.4    Shen, N.5    Chen, S.6


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