Enhanced selection of FoxP3+ T-regulatory cells protects CTLA-4-deficient mice from CNS autoimmune disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 9, 2009, Pages 3306-3311

  Verhagen, Johan ^a   Gabryšová, Leona ^a   Minaee, Sophie ^a   Sabatos, Catherine A ^a   Anderson, Graham ^b   Sharpe, Arlene H ^c   Wraith, David C ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Costimulation; Experimental autoimmune encephalomyelitis; Thymus suppression

Indexed keywords

CD28 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; MYELIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; ENCEPHALOMYELITIS; FEMALE; GENE EXPRESSION; GENE REPRESSION; LYMPHOPROLIFERATIVE DISEASE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; THYMUS;

ANIMALS; ANTIGENS, CD; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE DELETION; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MALE; MICE; MICE, KNOCKOUT; SPLEEN; THYMUS GLAND;

MUS;

EID: 62549084354     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0803186106     Document Type: Article

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