-
1
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot, J. D., M. A. Gavin, and A. Y. Rudensky. 2003. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 4: 330-336.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
2
-
-
34247277666
-
Foxp3 in control of the regulatory T cell lineage
-
Zheng, Y., and A. Y. Rudensky. 2007. Foxp3 in control of the regulatory T cell lineage. Nat. Immunol. 8: 457-462.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 457-462
-
-
Zheng, Y.1
Rudensky, A.Y.2
-
3
-
-
0348223787
-
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
Chen, W., W. Jin, N. Hardegen, K. J. Lei, L. Li, N. Marinos, G. McGrady, and S. M. Wahl. 2003. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J. Exp. Med. 198: 1875-1886.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.J.4
Li, L.5
Marinos, N.6
McGrady, G.7
Wahl, S.M.8
-
4
-
-
2142645808
-
Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7
-
Fantini, M. C., C. Becker, G. Monteleone, F. Pallone, P. R. Galle, and M. F. Neurath. 2004. Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7. J. Immunol. 172: 5149-5153.
-
(2004)
J. Immunol.
, vol.172
, pp. 5149-5153
-
-
Fantini, M.C.1
Becker, C.2
Monteleone, G.3
Pallone, F.4
Galle, P.R.5
Neurath, M.F.6
-
5
-
-
10344220512
-
CD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion
-
Curotto de Lafaille, M. A., A. C. Lino, N. Kutchukhidze, and J. J. Lafaille. 2004. CD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion. J. Immunol. 173: 7259-7268.
-
(2004)
J. Immunol.
, vol.173
, pp. 7259-7268
-
-
Curotto De Lafaille, M.A.1
Lino, A.C.2
Kutchukhidze, N.3
Lafaille, J.J.4
-
6
-
-
29244435493
-
Inducing and expanding regulatory T cell populations by foreign antigen
-
Kretschmer, K., I. Apostolou, D. Hawiger, K. Khazaie, M. C. Nussenzweig, and H. von Boehmer. 2005. Inducing and expanding regulatory T cell populations by foreign antigen. Nat. Immunol. 6: 1219-1227.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1219-1227
-
-
Kretschmer, K.1
Apostolou, I.2
Hawiger, D.3
Khazaie, K.4
Nussenzweig, M.C.5
Von Boehmer, H.6
-
7
-
-
44649144463
-
Autoantigen-specific TGFbeta-induced Foxp3+ regulatory T cells prevent autoimmunity by inhibiting dendritic cells from activating autoreactive T cells
-
DiPaolo, R. J., C. Brinster, T. S. Davidson, J. Andersson, D. Glass, and E. M. Shevach. 2007. Autoantigen-specific TGFbeta-induced Foxp3+ regulatory T cells prevent autoimmunity by inhibiting dendritic cells from activating autoreactive T cells. J. Immunol. 179: 4685-4693.
-
(2007)
J. Immunol.
, vol.179
, pp. 4685-4693
-
-
DiPaolo, R.J.1
Brinster, C.2
Davidson, T.S.3
Andersson, J.4
Glass, D.5
Shevach, E.M.6
-
8
-
-
50549102020
-
TGF-beta-induced Foxp3+ regulatory T cells rescue scurfy mice
-
Huter, E. N., G. A. Punkosdy, D. D. Glass, L. I. Cheng, J. M. Ward, and E. M. Shevach. 2008. TGF-beta-induced Foxp3+ regulatory T cells rescue scurfy mice. Eur. J. Immunol. 38: 1814-1821.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 1814-1821
-
-
Huter, E.N.1
Punkosdy, G.A.2
Glass, D.D.3
Cheng, L.I.4
Ward, J.M.5
Shevach, E.M.6
-
9
-
-
48249143387
-
Mitigation of experimental allergic encephalomyelitis by TGF-beta induced Foxp3+ regulatory T lymphocytes through the induction of anergy and infectious tolerance
-
Selvaraj, R. K., and T. L. Geiger. 2008. Mitigation of experimental allergic encephalomyelitis by TGF-beta induced Foxp3+ regulatory T lymphocytes through the induction of anergy and infectious tolerance. J. Immunol. 180: 2830-2838.
-
(2008)
J. Immunol.
, vol.180
, pp. 2830-2838
-
-
Selvaraj, R.K.1
Geiger, T.L.2
-
10
-
-
33645786794
-
Adaptive islet-specific regulatory CD4 T cells control autoimmune diabetes and mediate the disappearance of pathogenic Th1 cells in vivo
-
Weber, S. E., J. Harbertson, E. Godebu, G. A. Mros, R. C. Padrick, B. D. Carson, S. F. Ziegler, and L. M. Bradley. 2006. Adaptive islet-specific regulatory CD4 T cells control autoimmune diabetes and mediate the disappearance of pathogenic Th1 cells in vivo. J. Immunol. 176: 4730-4739.
-
(2006)
J. Immunol.
, vol.176
, pp. 4730-4739
-
-
Weber, S.E.1
Harbertson, J.2
Godebu, E.3
Mros, G.A.4
Padrick, R.C.5
Carson, B.D.6
Ziegler, S.F.7
Bradley, L.M.8
-
11
-
-
14244260068
-
DNA methylation and the expanding epigenetics of T cell lineage commitment
-
Wilson, C. B., K. W. Makar, M. Shnyreva, and D. R. Fitzpatrick. 2005. DNA methylation and the expanding epigenetics of T cell lineage commitment. Semin. Immunol. 17: 105-119.
-
(2005)
Semin. Immunol.
, vol.17
, pp. 105-119
-
-
Wilson, C.B.1
Makar, K.W.2
Shnyreva, M.3
Fitzpatrick, D.R.4
-
12
-
-
33846980131
-
Epigenetic control of the foxp3 locus in regulatory T cells
-
Floess, S., J. Freyer, C. Siewert, U. Baron, S. Olek, J. Polansky, K. Schlawe, H. D. Chang, T. Bopp, E. Schmitt, et al. 2007. Epigenetic control of the foxp3 locus in regulatory T cells. PLoS Biol. 5: e38.
-
(2007)
PLoS Biol.
, vol.5
-
-
Floess, S.1
Freyer, J.2
Siewert, C.3
Baron, U.4
Olek, S.5
Polansky, J.6
Schlawe, K.7
Chang, H.D.8
Bopp, T.9
Schmitt, E.10
-
13
-
-
34447265236
-
CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: A role for DNA methylation
-
Kim, H. P., and W. J. Leonard. 2007. CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation. J. Exp. Med. 204: 1543-1551.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1543-1551
-
-
Kim, H.P.1
Leonard, W.J.2
-
14
-
-
34548755672
-
DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells
-
Baron, U., S. Floess, G. Wieczorek, K. Baumann, A. Grützkau, J. Dong, A. Thiel, T. J. Boeld, P. Hoffmann, M. Edinger, et al. 2007. DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells. Eur. J. Immunol. 37: 2378-2389.
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 2378-2389
-
-
Baron, U.1
Floess, S.2
Wieczorek, G.3
Baumann, K.4
Grützkau, A.5
Dong, J.6
Thiel, A.7
Boeld, T.J.8
Hoffmann, P.9
Edinger, M.10
-
15
-
-
45449095936
-
FOXP3 promoter demethylation reveals the committed Treg population in humans
-
Janson, P. C., M. E. Winerdal, P. Marits, M. Thorn, R. Ohlsson, and O. Winqvist. 2008. FOXP3 promoter demethylation reveals the committed Treg population in humans. PLoS One 3: e1612.
-
(2008)
PLoS One
, vol.3
-
-
Janson, P.C.1
Winerdal, M.E.2
Marits, P.3
Thorn, M.4
Ohlsson, R.5
Winqvist, O.6
-
16
-
-
58849118836
-
Epigenetic control of FOXP3 expression: The key to a stable regulatory T-cell lineage?
-
Huehn, J., J. K. Polansky, and A. Hamann. 2009. Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage? Nat. Rev. Immunol. 9: 83-89.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 83-89
-
-
Huehn, J.1
Polansky, J.K.2
Hamann, A.3
-
17
-
-
70449717294
-
Epigenetic mechanisms of regulation of Foxp3 expression
-
Lal, G., and J. S. Bromberg. 2009. Epigenetic mechanisms of regulation of Foxp3 expression. Blood 114: 3727-3735.
-
(2009)
Blood
, vol.114
, pp. 3727-3735
-
-
Lal, G.1
Bromberg, J.S.2
-
18
-
-
49649107703
-
DNA methylation controls Foxp3 gene expression
-
Polansky, J. K., K. Kretschmer, J. Freyer, S. Floess, A. Garbe, U. Baron, S. Olek, A. Hamann, H. von Boehmer, and J. Huehn. 2008. DNA methylation controls Foxp3 gene expression. Eur. J. Immunol. 38: 1654-1663.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 1654-1663
-
-
Polansky, J.K.1
Kretschmer, K.2
Freyer, J.3
Floess, S.4
Garbe, A.5
Baron, U.6
Olek, S.7
Hamann, A.8
Von Boehmer, H.9
Huehn, J.10
-
19
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli, E., Y. Carrier, W. Gao, T. Korn, T. B. Strom, M. Oukka, H. L. Weiner, and V. K. Kuchroo. 2006. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441: 235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn, T.4
Strom, T.B.5
Oukka, M.6
Weiner, H.L.7
Kuchroo, V.K.8
-
20
-
-
38949164425
-
Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway
-
Elias, K. M., A. Laurence, T. S. Davidson, G. Stephens, Y. Kanno, E. M. Shevach, and J. J. O'Shea. 2008. Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway. Blood 111: 1013-1020.
-
(2008)
Blood
, vol.111
, pp. 1013-1020
-
-
Elias, K.M.1
Laurence, A.2
Davidson, T.S.3
Stephens, G.4
Kanno, Y.5
Shevach, E.M.6
O'Shea, J.J.7
-
21
-
-
59749089572
-
A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta
-
Corrected Article
-
Selvaraj, R. K., and T. L. Geiger. 2007. A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta. J. Immunol. 179: 1390 [Corrected Article].
-
(2007)
J. Immunol.
, vol.179
, pp. 1390
-
-
Selvaraj, R.K.1
Geiger, T.L.2
-
22
-
-
33645465526
-
Selective stimulation of T cell subsets with antibody-cytokine immune complexes
-
Boyman, O., M. Kovar, M. P. Rubinstein, C. D. Surh, and J. Sprent. 2006. Selective stimulation of T cell subsets with antibody-cytokine immune complexes. Science 311: 1924-1927.
-
(2006)
Science
, vol.311
, pp. 1924-1927
-
-
Boyman, O.1
Kovar, M.2
Rubinstein, M.P.3
Surh, C.D.4
Sprent, J.5
-
23
-
-
65549091509
-
In vivo expansion of T reg cells with IL-2-mAb complexes: Induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression
-
Webster, K. E., S. Walters, R. E. Kohler, T. Mrkvan, O. Boyman, C. D. Surh, S. T. Grey, and J. Sprent. 2009. In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression. J. Exp. Med. 206: 751-760.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 751-760
-
-
Webster, K.E.1
Walters, S.2
Kohler, R.E.3
Mrkvan, T.4
Boyman, O.5
Surh, C.D.6
Grey, S.T.7
Sprent, J.8
-
24
-
-
15444374646
-
Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
-
Setoguchi, R., S. Hori, T. Takahashi, and S. Sakaguchi. 2005. Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J. Exp. Med. 201: 723-735.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 723-735
-
-
Setoguchi, R.1
Hori, S.2
Takahashi, T.3
Sakaguchi, S.4
-
25
-
-
42149145285
-
Ex vivo generated regulatory T cells modulate experimental autoimmune myasthenia gravis
-
Aricha, R., T. Feferman, S. Fuchs, and M. C. Souroujon. 2008. Ex vivo generated regulatory T cells modulate experimental autoimmune myasthenia gravis. J. Immunol. 180: 2132-2139.
-
(2008)
J. Immunol.
, vol.180
, pp. 2132-2139
-
-
Aricha, R.1
Feferman, T.2
Fuchs, S.3
Souroujon, M.C.4
-
26
-
-
77958013857
-
Enhancement of antigen-specific Treg vaccination in vivo
-
Daniel, C., K. Wennhold, H. J. Kim, and H. von Boehmer. 2010. Enhancement of antigen-specific Treg vaccination in vivo. Proc. Natl. Acad. Sci. USA 107: 16246-16251.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 16246-16251
-
-
Daniel, C.1
Wennhold, K.2
Kim, H.J.3
Von Boehmer, H.4
-
27
-
-
33644556146
-
Prolonged TCR/CD28 engagement drives IL-2-independent T cell clonal expansion through signaling mediated by the mammalian target of rapamycin
-
Colombetti, S., V. Basso, D. L. Mueller, and A. Mondino. 2006. Prolonged TCR/CD28 engagement drives IL-2-independent T cell clonal expansion through signaling mediated by the mammalian target of rapamycin. J. Immunol. 176: 2730-2738.
-
(2006)
J. Immunol.
, vol.176
, pp. 2730-2738
-
-
Colombetti, S.1
Basso, V.2
Mueller, D.L.3
Mondino, A.4
-
28
-
-
4544241811
-
Tolerance, not immunity, crucially depends on IL-2
-
Malek, T. R., and A. L. Bayer. 2004. Tolerance, not immunity, crucially depends on IL-2. Nat. Rev. Immunol. 4: 665-674.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 665-674
-
-
Malek, T.R.1
Bayer, A.L.2
-
29
-
-
68949120834
-
The initial phase of an immune response functions to activate regulatory T cells
-
O'Gorman, W. E., H. Dooms, S. H. Thorne, W. F. Kuswanto, E. F. Simonds, P. O. Krutzik, G. P. Nolan, and A. K. Abbas. 2009. The initial phase of an immune response functions to activate regulatory T cells. J. Immunol. 183: 332-339.
-
(2009)
J. Immunol.
, vol.183
, pp. 332-339
-
-
O'Gorman, W.E.1
Dooms, H.2
Thorne, S.H.3
Kuswanto, W.F.4
Simonds, E.F.5
Krutzik, P.O.6
Nolan, G.P.7
Abbas, A.K.8
-
30
-
-
76749133610
-
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
-
Zheng, Y., S. Josefowicz, A. Chaudhry, X. P. Peng, K. Forbush, and A. Y. Rudensky. 2010. Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature 463: 808-812.
-
(2010)
Nature
, vol.463
, pp. 808-812
-
-
Zheng, Y.1
Josefowicz, S.2
Chaudhry, A.3
Peng, X.P.4
Forbush, K.5
Rudensky, A.Y.6
-
31
-
-
35448930435
-
Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype
-
Tran, D. Q., H. Ramsey, and E. M. Shevach. 2007. Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype. Blood 110: 2983-2990.
-
(2007)
Blood
, vol.110
, pp. 2983-2990
-
-
Tran, D.Q.1
Ramsey, H.2
Shevach, E.M.3
-
32
-
-
48249098821
-
Epigenetic inheritance of DNA methylation limits activation-induced expression of FOXP3 in conventional human CD25-CD4+ T cells
-
Nagar, M., H. Vernitsky, Y. Cohen, D. Dominissini, Y. Berkun, G. Rechavi, N. Amariglio, and I. Goldstein. 2008. Epigenetic inheritance of DNA methylation limits activation-induced expression of FOXP3 in conventional human CD25-CD4+ T cells. Int. Immunol. 20: 1041-1055.
-
(2008)
Int. Immunol.
, vol.20
, pp. 1041-1055
-
-
Nagar, M.1
Vernitsky, H.2
Cohen, Y.3
Dominissini, D.4
Berkun, Y.5
Rechavi, G.6
Amariglio, N.7
Goldstein, I.8
-
33
-
-
33846923124
-
IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells
-
Zheng, S. G., J. Wang, P. Wang, J. D. Gray, and D. A. Horwitz. 2007. IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells. J. Immunol. 178: 2018-2027.
-
(2007)
J. Immunol.
, vol.178
, pp. 2018-2027
-
-
Zheng, S.G.1
Wang, J.2
Wang, P.3
Gray, J.D.4
Horwitz, D.A.5
|