Strategies for controlled delivery of biologics for cartilage repair

Advanced Drug Delivery Reviews

Volumn 84, Issue , 2015, Pages 123-134

  Lam, Johnny ^a   Lu, Steven ^a   Kasper, F Kurtis ^a   Mikos, Antonios G ^a  

^a Rice University   (United States)

Author keywords

Cartilage tissue engineering; Controlled release; Drug delivery; Growth factors; Osteochondral repair; Spatiotemporal strategies

Indexed keywords

BIOACTIVITY; CARTILAGE; DRUG DELIVERY; TARGETED DRUG DELIVERY; TISSUE; TISSUE ENGINEERING;

CARTILAGE TISSUE ENGINEERING; CONTROLLED RELEASE; GROWTH FACTOR; OSTEOCHONDRAL REPAIRS; SPATIOTEMPORAL STRATEGIES;

CONTROLLED DRUG DELIVERY;

3,4,6 O TRIBUTANOYLATED N ACETYLGLUCOSAMINE; ALGINIC ACID; ANGIOGENIC FACTOR; ANTIINFLAMMATORY AGENT; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BOVINE SERUM ALBUMIN; CHONDROITIN SULFATE; FIBROBLAST GROWTH FACTOR 2; GROWTH FACTOR; HYALURONIC ACID; IBUPROFEN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; MICROPARTICLE; MOLECULAR SCAFFOLD; NANOPARTICLE; OLIGO[POLY(ETHYLENE GLYCOL)FUMARATE]; OSTEOGENIC PROTEIN 1; PARATHYROID HORMONE; PARATHYROID HORMONE RELATED PROTEIN; PROSTAGLANDIN E2; PROTEOGLYCAN 4; SOMATOMEDIN C; STROMAL CELL DERIVED FACTOR 1; SULFORAPHANE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; UNCLASSIFIED DRUG; UNINDEXED DRUG; BIOLOGICAL FACTOR;

ANTIINFLAMMATORY ACTIVITY; BIODEGRADABILITY; BONE TISSUE; BULK PHASE DELIVERY; CALCIFICATION; CARTILAGE; CARTILAGE CELL; CARTILAGE REPAIR; CELL DIFFERENTIATION; CELL HOMING; CELL INFILTRATION; CELL MATURATION; CELL PROLIFERATION; CELL TRANSPORT; CHONDROGENESIS; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; GEL; GENE THERAPY; GROWTH INHIBITION; HOMEOSTASIS; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; INJECTION; INTRAARTICULAR DRUG ADMINISTRATION; MESENCHYMAL STEM CELL; MUSCULOSKELETAL DEVELOPMENT; NONHUMAN; OSTEOARTHRITIS; OSTEOCHONDRAL TISSUE; OSTEOCHONDRITIS; OUTCOME ASSESSMENT; PALLIATIVE THERAPY; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SPATIALLY CONTROLLED DELIVERY; STATIC ELECTRICITY; TEMPORALLY CONTROLLED DELIVERY; THROMBOCYTE RICH PLASMA; TISSUE ENGINEERING; TISSUE REGENERATION; TREATMENT DURATION; UPREGULATION; WOUND HEALING; ARTICULAR CARTILAGE; DRUG EFFECTS; HUMAN; PHYSIOLOGY; PROCEDURES;

BIOLOGICAL FACTORS; CARTILAGE, ARTICULAR; DRUG DELIVERY SYSTEMS; HUMANS;

EID: 84929133804     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2014.06.006     Document Type: Review

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