A transduced living hyaline cartilage graft releasing transgenic stromal cell-derived factor-1 inducing endogenous stem cell homing in vivo

Tissue Engineering - Part A

Volumn 19, Issue 9-10, 2013, Pages 1091-1099

  Zhang, Feng ^a   Leong, Wenyan ^a   Su, Kai ^a   Fang, Yu ^a   Wang, Dong An ^a  

^a Nanyang Technological University   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CARTILAGE; CELL CULTURE; CELL PROLIFERATION; FLOW CYTOMETRY; MAMMALS; STEM CELLS; TISSUE;

ADENOVIRAL VECTORS; BIOLOGICAL ANALYSIS; CELL POPULATIONS; CIRCULATION SYSTEMS; ENDOGENOUS STEM CELLS; FLOW CYTOMETRY ANALYSIS; HYALINE CARTILAGE; SYSTEMIC CIRCULATION;

TISSUE REGENERATION;

ADENOVIRIDAE; ANIMALIA; MUS MUSCULUS;

STROMAL CELL DERIVED FACTOR 1;

ANIMAL; ARTICLE; CARTILAGE CELL; CELL CULTURE; CELL MOTION; CHONDROGENESIS; CYTOLOGY; GENE VECTOR; GENETICS; HYALINE CARTILAGE; METABOLISM; MOUSE; NUDE MOUSE; PHYSIOLOGY; STEM CELL; TISSUE ENGINEERING; TRANSGENIC MOUSE;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; CHEMOKINE CXCL12; CHONDROCYTES; CHONDROGENESIS; GENETIC VECTORS; HYALINE CARTILAGE; MICE; MICE, NUDE; MICE, TRANSGENIC; STEM CELLS; TISSUE ENGINEERING;

EID: 84875634509     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2012.0441     Document Type: Article

References (27)

1. Grunewald, M., Avraham, I., Dor, Y., Bachar-Lustig, E., Itin, A., Jung, S., et al. VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells. Cell 124, 175, 2006.
2. Kucia, M., Ratajczak, J., Reca, R., Janowska-Wieczorek, A., and Ratajczak, M.Z. Tissue-specific muscle, neural and liver stem/progenitor cells reside in the bone marrow, respond to an SDF-1 gradient and are mobilized into peripheral blood during stress and tissue injury. Blood Cells Mol Dis 32, 52, 2004.
3. Ponomaryov, T., Peled, A., Petit, I., Taichman, R.S., Habler, L., Sandbank, J., et al. Induction of the chemokine stromalderived factor-1 following DNA damage improves human stem cell function. J Clin Invest 106, 1331, 2000.
4. Kollet, O., Shivtiel, S., Chen, Y.Q., Suriawinata, J., Thung, S.N., Dabeva, M.D., et al. HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34 + stem cell recruitment to the liver. J Clin Invest 112, 160, 2003.
5. Aiuti, A., Webb, I.J., Bleul, C., Springer, T., & Gutierrez-Ramos, J.C. The chemokine SDF-1 is a chemoattractant for human CD34 + hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34 + progenitors to peripheral blood. J Exp Med 185, 111, 1997.
6. Ding, Z., Issekutz, T.B., Downey, G.P., & Waddell, T.K. L-selectin stimulation enhances functional expression of surface CXCR4 in lymphocytes: implications for cellular activation during adhesion and migration. Blood 101, 4245, 2003.
7. Peled, A., Kollet, O., Ponomaryov, T., Petit, I., Franitza, S., Grabovsky, V., et al. The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34 (+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice. Blood 95, 3289, 2000.
8. Wang, W., Li, W., Ong, L.L., Lutzow, K., Lendlein, A., Furlani, D., et al. Localized and sustained SDF-1 gene release mediated by fibronectin films: A potential method for recruiting stem cells. Int J Artif Organs 32, 141, 2009.
9. Bhakta, S., Hong, P., & Koc, O. The surface adhesion molecule CXCR4 stimulates mesenchymal stem cell migration to stromal cell-derived factor-1 in vitro but does not decrease apoptosis under serum deprivation. Cardiovasc Revasc Med 7, 19, 2006.
10. Son, B.R., Marquez-Curtis, L.A., Kucia, M., Wysoczynski, M., Turner, A.R., Ratajczak, J., et al. Migration of bone marrow and cord blood mesenchymal stem cells in vitro is regulated by stromal-derived factor-1-CXCR4 and hepatocyte growth factor-c-met axes and involves matrix metalloproteinases. Stem Cells 24, 1254, 2006.
11. Wynn, R.F., Hart, C.A., Corradi-Perini, C., O'Neill, L., Evans, C.A., Wraith, J.E., et al. A small proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow. Blood 104, 2643, 2004.
12. Somers, T.J., Keefe, F.J., Godiwala, N., & Hoyler, G.H. Psychosocial factors and the pain experience of osteoarthritis patients: new findings and new directions. Curr Opin Rheumatol 21, 501, 2009.
13. Su, K., Lau, T. T., Leong, W.Y., Gong, Y.H., & Wang, D. A. Creating a living hyaline cartilage graft free of noncartilaginous constituents: an intermediate role of biomaterial scaffold. Adv Funct Mater 22, 972, 2012.
14. Gong, Y., Su, K., Lau, T.T., Zhou, R., & Wang, D.A. Microcavitary hydrogel-mediating phase transfer cell culture for cartilage tissue engineering. Tissue Eng Part A 16, 3611, 2010.
15. Ameer, G.A., & Mahmood, T.A., Langer, R. A biodegradable composite scaffold for cell transplantation. J Orthop Res 20, 16, 2002.
16. Kim, Y.J., Sah, R.L., Doong, J.Y., & Grodzinsky, A.J. Fluorometric assay of DNA in cartilage explants using Hoechst 33258. Anal Biochem 174, 168, 1988.
17. Freed, L.E., Hollander, A.P., Martin, I., Barry, J.R., Langer, R., & Vunjak-Novakovic, G. Chondrogenesis in a cellpolymer-bioreactor system. Exp Cell Res 240, 58, 1998.
18. Farndale, R.W., Buttle, D.J., & Barrett, A.J. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta 883, 173, 1986.
19. Freed, L.E., Marquis, J.C., Nohria, A., Emmanual, J., Mikos, A.G., & Langer, R. Neocartilage formation in vitro and in vivo using cells cultured on synthetic biodegradable polymers. J Biomed Mater Res 27, 11, 1993.
20. Tang, J., Wang, J., Yang, J., Kong, X., Zheng, F., Guo, L., et al. Mesenchymal stem cells over-expressing SDF-1 promote angiogenesis and improve heart function in experimental myocardial infarction in rats. Eur J Cardiothorac Surg 36, 644, 2009.
21. Badillo, A.T., Chung, S., Zhang, L., Zoltick, P., & Liechty, K.W. Lentiviral gene transfer of SDF-1 alpha to wounds improves diabetic wound healing. J Surg Res 143, 35, 2007.
22. Wright, D.E., Bowman, E.P., Wagers, A.J., Butcher, E.C., and Weissman, I.L. Hematopoietic stem cells are uniquely selective in their migratory response to chemokines. J Exp Med 195, 1145, 2002.
23. Lin, G., Finger, E., & Gutierrez-Ramos, J.C. Expression of CD34 in endothelial cells, hematopoietic progenitors and nervous cells in fetal and adult mouse tissues. Eur J Immunol 25, 1508, 1995.
24. Aldridge, V., Garg, A., Davies, N., Bartlett, D.C., Youster, J., Beard, H., et al. Human mesenchymal stem cells are recruited to injured liver in a beta1 integrin and CD44 dependent manner. Hepatology 56, 1063, 2012.
25. Levesque, J.P., Liu, F., Simmons, P.J., Betsuyaku, T., Senior, R.M., Pham, C., et al. Characterization of hematopoietic progenitor mobilization in protease-deficient mice. Blood 104, 65, 2004.
26. Spangrude, G.J., & Brooks, D.M. Mouse strain variability in the expression of the hematopoietic stem cell antigen Ly-6A/E by bone marrow cells. Blood 82, 3327, 1993.
27. Goodison, S., Urquidi, V., & Tarin, D. CD44 cell adhesion molecules. Mol Pathol 52, 189, 1999.