The effect of platelet-rich plasma on autologous osteochondral transplantation :An in vivo rabbit model

Journal of Bone and Joint Surgery

Volumn 95, Issue 24, 2013, Pages 2185-2193

  Smyth, Niall A ^a   Haleem, Amgad M ^a   Murawski, Christopher D ^a   Do, Huong T ^a   Deland, Jonathan T ^a   Kennedy, John G ^a  

^a HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOLOGOUS OSTEOCHONDRAL TRANSPLANTATION; AUTOTRANSPLANTATION; CARTILAGE DEGENERATION; CONTROLLED STUDY; EXPERIMENTAL RABBIT; FEMUR CONDYLE; NONHUMAN; PRIORITY JOURNAL; SCORING SYSTEM; THROMBOCYTE RICH PLASMA; ANIMAL; ARTICULAR CARTILAGE; BONE TRANSPLANTATION; CARTILAGE; CARTILAGE CELL; GRAFT SURVIVAL; KNEE; PROCEDURES; RABBIT; SURGERY; TRANSPLANTATION; METHODOLOGY;

ANIMALS; BONE TRANSPLANTATION; CARTILAGE; CARTILAGE, ARTICULAR; CHONDROCYTES; GRAFT SURVIVAL; KNEE JOINT; MODELS, ANIMAL; PLATELET-RICH PLASMA; RABBITS; TRANSPLANTATION, AUTOLOGOUS;

EID: 84894308170     PISSN: 00219355     EISSN: 15351386     Source Type: Journal    
DOI: 10.2106/JBJS.L.01497     Document Type: Article

References (59)

1. Mankin HJ. The response of articular cartilage to mechanical injury. J Bone Joint Surg Am. 1982 Mar;64(3):460-6
2. Jackson DW, Lalor PA, Aberman HM, Simon TM. Spontaneous repair of fullthickness defects of articular cartilage in a goat model. A preliminary study. J Bone Joint Surg Am. 2001 Jan;83-A(1):53-64
3. Buckwalter JA, Mankin HJ. Articular cartilage repair and transplantation. Arthritis Rheum. 1998 Aug;41(8):1331-42
4. Bedi A, Feeley BT, Williams RJ 3rd. Management of articular cartilage defects of the knee. J Bone Joint Surg Am. 2010 Apr;92(4):994-1009
5. O'Loughlin PF, Heyworth BE, Kennedy JG. Current concepts in the diagnosis and treatment of osteochondral lesions of the ankle. Am J Sports Med. 2010 Feb;38(2):392-404. Epub 2009 Jun 26
6. Scranton PE Jr., Frey CC, Feder KS. Outcome of osteochondral autograft transplantation for type-V cystic osteochondral lesions of the talus. J Bone Joint Surg Br. 2006 May;88(5):614-9
7. Imhoff AB, Paul J, Ottinger B, Wortler K, Lammle L, Spang J, Hinterwimmer S. Osteochondral transplantation of the talus: long-termclinical and magnetic resonance imaging evaluation. Am J Sports Med. 2011 Jul;39(7):1487-93. Epub 2011 Mar 03
8. Kennedy JG, Murawski CD. The treatment of osteochondral lesions of the talus with autologous osteochondral transplantation and bone marrow aspirate concentrate: surgical technique. Cartilage. 2011 Oct;2(4):327-36
9. Paul J, Sagstetter M, Lammle L, Spang J, El-Azab H, Imhoff AB, Hinterwimmer S. Sports activity after osteochondral transplantation of the talus. Am J Sports Med. 2012 Apr;40(4):870-4. Epub 2012 Jan 20
10. Hangody L, Fules P. Autologous osteochondral mosaicplasty for the treatment of full-thickness defects of weight-bearing joints: ten years of experimental and clinical experience. J Bone Joint Surg Am. 2003;85(Suppl 2):25-32
11. Hangody L, V́aśarhelyi G, Hangody LR, Sukosd Z, Tibay G, Bartha L, Bod́o G. Autologous osteochondral grafting -technique and long-term results. Injury. 2008 Apr;39 Suppl 1:S32-9
12. Gudas R, Gudaite A, Pocius A, Gudiene A, Cekanauskas E, Monastyreckiene E, Basevicius A. Ten-year follow-up of a prospective, randomized clinical study of mosaic osteochondral autologous transplantation versus microfracture for the treatment of osteochondral defects in the knee joint of athletes. Am J Sports Med. 2012 Nov;40(11):2499-508. Epub 2012 Sep 28
13. Marcacci M, Kon E, Delcogliano M, Filardo G, Busacca M, Zaffagnini S. Arthroscopic autologous osteochondral grafting for cartilage defects of the knee: prospective study results at a minimum 7-year follow-up. Am J Sports Med. 2007 Dec;35(12):2014-21. Epub 2007 Aug 27
14. Evans NA, Jackson DW, Simon TM. MRI and histologic evaluation of two cases of osteochondral autograft transplantation procedures. J Knee Surg. 2005 Jan;18(1):43-8
15. Valderrabano V, Leumann A, Rasch H, Egelhof T, Hintermann B, Pagenstert G. Knee-to-Ankle mosaicplasty for the treatment of osteochondral lesions of the ankle joint. Am J Sports Med. 2009 Nov;37 Suppl 1:105S-11S. Epub 2009 Oct 19
16. Siebert CH, Miltner O, Weber M, Sopka S, Koch S, Niedhart C. Healing of osteochondral grafts in an ovine model under the influence of bFGF. Arthroscopy. 2003 Feb;19(2):182-7
17. Tibesku CO, Daniilidis K, Szuwart T, Jahn UR, Schlegel PM, Fuchs-Winkelmann S. Influence of hepatocyte growth factor on autologous osteochondral transplants in an animal model. Arch Orthop Trauma Surg. 2011 Aug;131(8):1145-51. Epub 2011 Feb 27
18. Siebert CH, Schneider U, Sopka S, Wahner T, Miltner O, Niedhart C. Ingrowth of osteochondral grafts under the influence of growth factors: 6-month results of an animal study. Arch Orthop Trauma Surg. 2006 May;126(4):247-52. Epub 2005 Dec 15
19. Fortier LA, Barker JU, Strauss EJ, McCarrel TM, Cole BJ. The role of growth factors in cartilage repair. Clin Orthop Relat Res. 2011 Oct;469(10):2706-15
20. Miller Y, Bachowski G, Benjamin R, Eklund DK, Hibbard AJ, Lightfoot T, Meena-Leist C, Quraishy N, Sapatnekar S, Squires J, Strupp A, Vassallo R, Weiss J. Practice guideline for blood transfusion: A compilation from recent peer-reviewed literature. 2nd ed. Washington: American Red Cross; 2012
21. Kruger JP, Hondke S, Endres M, Pruss A, Siclari A, Kaps C. Human platelet-rich plasma stimulates migration and chondrogenic differentiation of human subchondral progenitor cells. J Orthop Res. 2012 Jun;30(6):845-52. Epub 2011 Nov 04
22. Spreafico A, Chellini F, Frediani B, Bernardini G, Niccolini S, Serchi T, Collodel G, Paffetti A, Fossombroni V, Galeazzi M, Marcolongo R, Santucci A. Biochemical investigation of the effects of human platelet releasates on human articular chondrocytes. J Cell Biochem. 2009 Dec 1;108(5):1153-65
23. Mishra A, Tummala P, King A, Lee B, Kraus M, Tse V, Jacobs CR. Buffered platelet-rich plasma enhances mesenchymal stem cell proliferation and chondrogenic differentiation. Tissue Eng Part C Methods. 2009 Sep;15(3):431-5
24. Akeda K, An HS, Okuma M, AttawiaM,Miyamoto K, Thonar EJ, Lenz ME, Sah RL, Masuda K. Platelet-rich plasma stimulates porcine articular chondrocyte proliferation and matrix biosynthesis. Osteoarthritis Cartilage. 2006 Dec;14(12):1272-80. Epub 2006 Jul 03
25. Milano G, Sanna Passino E, Deriu L, Careddu G, Manunta L, Manunta A, Saccomanno MF, Fabbriciani C. The effect of platelet rich plasma combined with microfractures on the treatment of chondral defects: an experimental study in a sheep model. Osteoarthritis Cartilage. 2010 Jul;18(7):971-80. Epub 2010 Apr 28
26. Milano G, Deriu L, Sanna Passino E, Masala G, Manunta A, Postacchini R, Saccomanno MF, Fabbriciani C. Repeated platelet concentrate injections enhance reparative response of microfractures in the treatment of chondral defects of the knee: an experimental study in an animal model. Arthroscopy. 2012 May;28(5): 688-701. Epub 2012 Jan 25
27. Nakayama J, Fujioka H, Nagura I, Kokubu T, Makino T, Kuroda R, Tabata Y, Kurosaka M. The effect of fibroblast growth factor-2 on autologous osteochondral transplantation. Int Orthop. 2009 Feb;33(1):275-80. Epub 2007 Oct 17
28. Kuroki H, Nakagawa Y, Mori K, Kobayashi M, Okamoto Y, Yasura K, Nishitani K, Nakamura T. Sequential changes in implanted cartilage after autologous osteochondral transplantation: postoperative acoustic properties up to 1 year in an in vivo rabbit model. Arthroscopy. 2007 Jun;23(6):647-54
29. Makino T, Fujioka H, Terukina M, Yoshiya S, Matsui N, Kurosaka M. The effect of graft sizing on osteochondral transplantation. Arthroscopy. 2004 Oct;20(8):837-40
30. Smith GD, Taylor J, Almqvist KF, Erggelet C, Knutsen G, Garcia Portabella M, Smith T, Richardson JB. Arthroscopic assessment of cartilage repair: a validation study of 2 scoring systems. Arthroscopy. 2005 Dec; 21(12):1462-7
31. Gulotta LV, Rudzki JR, Kovacevic D, Chen CC, Milentijevic D, Williams RJ 3rd. Chondrocyte death and cartilage degradation after autologous osteochondral transplantation surgery in a rabbit model. Am J Sports Med. 2009 Jul;37(7): 1324-33. Epub 2009 May 15
32. Kock NB, Hannink G, van Kampen A, Verdonschot N, van Susante JL, Buma P. Evaluation of subsidence, chondrocyte survival and graft incorporation following autologous osteochondral transplantation. Knee Surg Sports Traumatol Arthrosc. 2011 Nov;19(11):1962-70. Epub 2011 Sep 09
33. Arøen A, Løken S, Heir S, Alvik E, Ekeland A, Granlund OG, Engebretsen L. Articular cartilage lesions in 993 consecutive knee arthroscopies. Am J Sports Med. 2004 Jan-Feb;32(1):211-5
34. Orr JD, Dawson LK, Garcia EJ, Kirk KL. Incidence of osteochondral lesions of the talus in the United States military. Foot Ankle Int. 2011 Oct;32(10):948-54
35. Horas U, Pelinkovic D, Herr G, Aigner T, Schnettler R. Autologous chondrocyte implantation and osteochondral cylinder transplantation in cartilage repair of the knee joint. A prospective, comparative trial. J Bone Joint Surg Am. 2003 Feb; 85-A(2):185-92
36. Hangody L, Fules P. Autologous osteochondral mosaicplasty for the treatment of full-thickness defects of weight-bearing joints: ten years of experimental and clinical experience. J Bone Joint Surg Am. 2003;85-A(Suppl 2):25-32
37. Scranton PE Jr., Frey CC, Feder KS. Outcome of osteochondral autograft transplantation for type-V cystic osteochondral lesions of the talus. J Bone Joint Surg Br. 2006 May;88(5):614-9
38. Marcacci M, Kon E, Delcogliano M, Filardo G, Busacca M, Zaffagnini S. Arthroscopic autologous osteochondral grafting for cartilage defects of the knee: prospective study results at a minimum 7-year follow-up. Am J Sports Med. 2007 Dec;35(12):2014-21. Epub 2007 Aug 27
39. D'Lima DD, Hashimoto S, Chen PC, Lotz MK, Colwell CW Jr. Cartilage injury induces chondrocyte apoptosis. J Bone Joint Surg Am. 2001;83-A(Pt 1)(Suppl 2):19-21
40. D'Lima DD, Hashimoto S, Chen PC, Colwell CWJr., LotzMK. Human chondrocyte apoptosis in response to mechanical injury. Osteoarthritis Cartilage. 2001 Nov;9(8):712-9
41. Chen CT, Burton-Wurster N, Borden C, Hueffer K, Bloom SE, Lust G. Chondrocyte necrosis and apoptosis in impact damaged articular cartilage. J Orthop Res. 2001 Jul;19(4):703-11
42. Borazjani BH, Chen AC, Bae WC, Patil S, Sah RL, Firestein GS, Bugbee WD. Effect of impact on chondrocyte viability during insertion of human osteochondral grafts. J Bone Joint Surg Am. 2006 Sep;88(9):1934-43
43. Patil S, Butcher W, D'Lima DD, Steklov N, Bugbee WD, Hoenecke HR. Effect of osteochondral graft insertion forces on chondrocyte viability. Am J Sports Med. 2008 Sep;36(9):1726-32. Epub 2008 May 19
44. Tibesku CO, Szuwart T, Kleffner TO, Schlegel PM, Jahn UR, Van Aken H, Fuchs S. Hyaline cartilage degenerates after autologous osteochondral transplantation. J Orthop Res. 2004 Nov;22(6):1210-4
45. Kleemann RU, Schell H, Thompson M, Epari DR, Duda GN, Weiler A. Mechanical behavior of articular cartilage after osteochondral autograft transfer in an ovine model. Am J Sports Med. 2007 Apr;35(4):555-63. Epub 2007 Feb 09
46. Lin PM, Chen CT, Torzilli PA. Increased stromelysin-1 (MMP-3), proteoglycan degradation (3B3-And 7D4) and collagen damage in cyclically load-injured articular cartilage. Osteoarthritis Cartilage. 2004 Jun;12(6):485-96
47. Lane JG, Tontz WL Jr., Ball ST, Massie JB, Chen AC, Bae WC, Amiel ME, Sah RL, Amiel D. A morphologic, biochemical, and biomechanical assessment of short-term effects of osteochondral autograft plug transfer in an animal model. Arthroscopy. 2001 Oct;17(8):856-63
48. Lane JG, Massie JB, Ball ST, Amiel ME, Chen AC, Bae WC, Sah RL, Amiel D. Follow-up of osteochondral plug transfers in a goat model: a 6-month study. Am J Sports Med. 2004 Sep;32(6):1440-50. Epub 2004 Jul 20
49. Sward P, Frobell R, Englund M, Roos H, Struglics A. Cartilage and bone markers and inflammatory cytokines are increased in synovial fluid in the acute phase of knee injury (hemarthrosis) -A cross-sectional analysis. Osteoarthritis Cartilage. 2012 Nov;20(11):1302-8
50. Wu CC, Chen WH, Zao B, Lai PL, Lin TC, Lo HY, Shieh YH, Wu CH, Deng WP. Regenerative potentials of platelet-rich plasma enhanced by collagen in retrieving pro-inflammatory cytokine-inhibited chondrogenesis. Biomaterials. 2011 Sep;32(25):5847-54. Epub 2011 May 25
51. van Buul GM, Koevoet WL, Kops N, Bos PK, Verhaar JA, Weinans H, Bernsen MR, van Osch GJ. Platelet-rich plasma releasate inhibits inflammatory processes in osteoarthritic chondrocytes. Am J Sports Med. 2011 Nov;39(11):2362-70. Epub 2011 Aug 19
52. Lee HR, Park KM, Joung YK, Park KD, Do SH. Platelet-rich plasma loaded hydrogel scaffold enhances chondrogenic differentiation and maturation with upregulation of CB1 and CB2. J Control Release. 2012 May 10;159(3):332-7. Epub 2012 Feb 15
53. Park SI, Lee HR, Kim S, Ahn MW, Do SH, Do Hee S. Time-sequential modulation in expression of growth factors from platelet-rich plasma (PRP) on the chondrocyte cultures. Mol Cell Biochem. 2012 Feb;361(1-2):9-17. Epub 2011 Sep 29
54. Zaky SH, Ottonello A, Strada P, Cancedda R, Mastrogiacomo M. Platelet lysate favours in vitro expansion of human bone marrow stromal cells for bone and cartilage engineering. J Tissue Eng Regen Med. 2008 Dec;2(8):472-81
55. Anitua E, Śanchez M, Nurden AT, Zalduendo MM, de la Fuente M, Azofra J, Andía I. Platelet-released growth factors enhance the secretion of hyaluronic acid and induce hepatocyte growth factor production by synovial fibroblasts from arthritic patients. Rheumatology (Oxford). 2007 Dec;46(12):1769-72. Epub 2007 Oct 17
56. Browning SR, Weiser AM, Woolf N, Golish SR, SanGiovanni TP, Scuderi GJ, Carballo C, Hanna LS. Platelet-rich plasma increases matrix metalloproteinases in cultures of human synovial fibroblasts. J Bone Joint Surg Am. 2012 Dec 5;94(23):e1721-7
57. Latt LD, Glisson RR, Montijo HE, Usuelli FG, Easley ME. Effect of graft height mismatch on contact pressures with osteochondral grafting of the talus. Am J Sports Med. 2011 Dec;39(12):2662-9. Epub 2011 Sep 21
58. Fansa AM, Murawski CD, Imhauser CW, Nguyen JT, Kennedy JG. Autologous osteochondral transplantation of the talus partially restores contact mechanics of the ankle joint. Am J Sports Med. 2011 Nov;39(11):2457-65. Epub 2011 Aug 25
59. Bulstra SK, Kuijer R, Eerdmans P, van der Linden AJ. The effect in vitro of irrigating solutions on intact rat articular cartilage. J Bone Joint Surg Br. 1994 May;76(3):468-70.