Repair of an osteochondral defect by sustained delivery of BMP-2 or TGFβ1 from a bilayered alginate-PLGA scaffold

Journal of Tissue Engineering and Regenerative Medicine

Volumn 8, Issue 7, 2014, Pages 521-533

  Reyes, R ^a   Delgado, A ^a   Sanchez E ^a   Fernandez A ^b   Hernandez A ^c   Evora, C ^a  

^a UNIVERSIDAD DE LA LAGUNA   (Spain)

^b HOSPITAL UNIVERSITARIO NUESTRA SEÑORA DE CANDELARIA   (Spain)

^c HOSPITEN Rambla   (Spain)

Author keywords

Alginate PLGA scaffold; BMP 2; Controlled release; Histology; Osteochondral repair; TGF 1

Indexed keywords

ALGINATE; BONE; MICROSPHERES; QUALITY CONTROL; REPAIR; SCAFFOLDS (BIOLOGY);

ALGINATE-PLGA SCAFFOLD; BILAYERED; BONE MORPHOGENETIC PROTEIN-2; CONTROLLED RELEASE; GROWTH FACTOR; IN-VITRO; OSTEOCHONDRAL DEFECTS; OSTEOCHONDRAL REPAIRS; PLGA SCAFFOLDS; TRANSFORMING GROWTH FACTOR-Β1;

CARTILAGE;

AGGRECAN; ALGINIC ACID; COLLAGEN TYPE 2; IODINE 125; MICROSPHERE; POLYGLACTIN; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT GROWTH FACTOR; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; BONE MORPHOGENETIC PROTEIN 2; COLLAGEN TYPE 1; DELAYED RELEASE FORMULATION; GLUCURONIC ACID; HEXURONIC ACID; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; BONE; CARTILAGE; CARTILAGE CELL; CELL FREE SYSTEM; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG RELEASE; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT MODEL; TISSUE DISTRIBUTION; TISSUE REPAIR; ANIMAL; ARTICULAR CARTILAGE; CELL COUNT; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG EFFECTS; FEMUR; METABOLISM; PATHOLOGY; PROSTHESIS IMPLANTATION; RABBIT; SPRAGUE DAWLEY RAT; TISSUE SCAFFOLD; WOUND HEALING;

AGGRECANS; ALGINATES; ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CARTILAGE, ARTICULAR; CELL COUNT; COLLAGEN TYPE I; COLLAGEN TYPE II; DELAYED-ACTION PREPARATIONS; FEMUR; GLUCURONIC ACID; HEXURONIC ACIDS; LACTIC ACID; MALE; POLYGLYCOLIC ACID; PROSTHESIS IMPLANTATION; RABBITS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION; TISSUE SCAFFOLDS; TRANSFORMING GROWTH FACTOR BETA1; WOUND HEALING;

EID: 84903820472     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.1549     Document Type: Article

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