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Volumn 41, Issue 1, 2015, Pages 85-94

In vitro evaluation of S-(+)-ibuprofen as drug candidate for intra-articular drug delivery system

Author keywords

Cartilage; Co culture; Drug delivery systems; Osteoarthritis; S (+) ibuprofen

Indexed keywords

AMYLOID PROTEIN; IBUPROFEN; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; PROTEOGLYCAN; NONSTEROID ANTIINFLAMMATORY AGENT;

EID: 84918771721     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2013.850704     Document Type: Article
Times cited : (5)

References (53)
  • 1
    • 4344646701 scopus 로고    scopus 로고
    • The IPSO study: Ibuprofen, paracetamol study in osteoarthritis. A randomised comparative clinical study comparing the efficacy and safety of ibuprofen and paracetamol analgesic treatment of osteoarthritis of the knee or hip
    • Boureau F, Schneid H, Zeghari N, et al. The IPSO study: ibuprofen, paracetamol study in osteoarthritis. A randomised comparative clinical study comparing the efficacy and safety of ibuprofen and paracetamol analgesic treatment of osteoarthritis of the knee or hip. Ann Rheum Dis 2004;63:1028-34.
    • (2004) Ann Rheum Dis , vol.63 , pp. 1028-1034
    • Boureau, F.1    Schneid, H.2    Zeghari, N.3
  • 2
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
    • Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature 1971;231:232-5.
    • (1971) Nature , vol.231 , pp. 232-235
    • Vane, J.R.1
  • 4
    • 0034665322 scopus 로고    scopus 로고
    • The induction of cell death in human osteoarthritis chondrocytes by nitric oxide is related to the production of prostaglandin E2 via the induction of cyclooxygenase-2
    • Notoya K, Jovanovic DV, Reboul P, et al. The induction of cell death in human osteoarthritis chondrocytes by nitric oxide is related to the production of prostaglandin E2 via the induction of cyclooxygenase-2. J Immunol 2000;165:3402-10.
    • (2000) J Immunol , vol.165 , pp. 3402-3410
    • Notoya, K.1    Jovanovic, D.V.2    Reboul, P.3
  • 5
    • 33746507884 scopus 로고    scopus 로고
    • Long term NSAID treatment inhibits COX-2 synthesis in the knee synovial membrane of patients with osteoarthritis: Differential proinflammatory cytokine profile between celecoxib and aceclofenac
    • Alvarez-Soria MA, Largo R, Santillana J, et al. Long term NSAID treatment inhibits COX-2 synthesis in the knee synovial membrane of patients with osteoarthritis: differential proinflammatory cytokine profile between celecoxib and aceclofenac. Ann Rheum Dis 2006; 65:998-1005.
    • (2006) Ann Rheum Dis , vol.65 , pp. 998-1005
    • Alvarez-Soria, M.A.1    Largo, R.2    Santillana, J.3
  • 6
    • 0037201760 scopus 로고    scopus 로고
    • Identification of degradation products of ibuprofen arising from oxidative and thermal treatments
    • Caviglioli G, Valeria P, Brunella P, et al. Identification of degradation products of ibuprofen arising from oxidative and thermal treatments. J Pharm Biomed Anal 2002;15:499-509.
    • (2002) J Pharm Biomed Anal , vol.15 , pp. 499-509
    • Caviglioli, G.1    Valeria, P.2    Brunella, P.3
  • 7
    • 38849123742 scopus 로고    scopus 로고
    • Ibuprofen: A journey from prescription to over-the-counter use
    • Moore N. Ibuprofen: a journey from prescription to over-the-counter use. J R Soc Med 2007;100(Suppl. 48):2-6.
    • (2007) J R Soc Med , vol.100 , pp. 2-6
    • Moore, N.1
  • 8
    • 0036228958 scopus 로고    scopus 로고
    • Metabolism of human articular chondrocytes cultured in alginate beads. Longterm effects of interleukin 1beta and nonsteroidal antiinflammatory drugs
    • Sanchez C, Mateus MM, Defresne MP, et al. Metabolism of human articular chondrocytes cultured in alginate beads. Longterm effects of interleukin 1beta and nonsteroidal antiinflammatory drugs. J Rheumatol 2002;29:772-82.
    • (2002) J Rheumatol , vol.29 , pp. 772-782
    • Sanchez, C.1    Mateus, M.M.2    Defresne, M.P.3
  • 9
    • 0035068730 scopus 로고    scopus 로고
    • Non-steroidal antiinflammatory drugs protect against chondrocyte apoptotic death
    • Mukherjee P, Rachita C, Aisen PS, Pasinetti GM. Non-steroidal antiinflammatory drugs protect against chondrocyte apoptotic death. Clin Exp Rheumatol 2001;19:S7-11.
    • (2001) Clin Exp Rheumatol , vol.19 , pp. S7-11
    • Mukherjee, P.1    Rachita, C.2    Aisen, P.S.3    Pasinetti, G.M.4
  • 10
    • 0024371904 scopus 로고
    • Effects of antirheumatic drugs on the interleukin-1 alpha induced synthesis and activation of proteinases in articular cartilage explants in culture
    • Arsenis C, McDonnell J. Effects of antirheumatic drugs on the interleukin-1 alpha induced synthesis and activation of proteinases in articular cartilage explants in culture. Agents Actions 1989;27: 261-4.
    • (1989) Agents Actions , vol.27 , pp. 261-264
    • Arsenis, C.1    McDonnell, J.2
  • 11
    • 33644825406 scopus 로고    scopus 로고
    • Comparative effect of nimesulide and ibuprofen on the urinary levels of collagen type II C-telopeptide degradation products and on the serum levels of hyaluronan and matrix metalloproteinases-3 and-13 in patients with flare-up of osteoarthritis
    • Manicourt DH, Bevilacqua M, Righini V, et al. Comparative effect of nimesulide and ibuprofen on the urinary levels of collagen type II C-telopeptide degradation products and on the serum levels of hyaluronan and matrix metalloproteinases-3 and-13 in patients with flare-up of osteoarthritis. Drugs RD 2005;6:261-71.
    • (2005) Drugs RD , vol.6 , pp. 261-271
    • Manicourt, D.H.1    Bevilacqua, M.2    Righini, V.3
  • 12
    • 3042784398 scopus 로고    scopus 로고
    • Effects of S-(+)-ibuprofen on molecular markers of cartilage and synovium turnover in patients with knee osteoarthritis
    • Gineyts E, Mo JA, Ko A, et al. Effects of S-(+)-ibuprofen on molecular markers of cartilage and synovium turnover in patients with knee osteoarthritis. Ann Rheum Dis 2004;63:857-61.
    • (2004) Ann Rheum Dis , vol.63 , pp. 857-861
    • Gineyts, E.1    Mo, J.A.2    Ko, A.3
  • 13
    • 84859560601 scopus 로고    scopus 로고
    • Osteoarthritis of the knee and hip. Part II: Therapy with ibuprofen and a review of clinical trials
    • Adatia A, Rainsford KD, Kean WF. Osteoarthritis of the knee and hip. Part II: therapy with ibuprofen and a review of clinical trials. J Pharm Pharmacol 2012;64:626-36.
    • (2012) J Pharm Pharmacol , vol.64 , pp. 626-636
    • Adatia, A.1    Rainsford, K.D.2    Kean, W.F.3
  • 14
    • 79955004744 scopus 로고    scopus 로고
    • Joint inflammation and early degeneration induced by high-force reaching are attenuated by ibuprofen in an animal model of work-related musculoskeletal disorder
    • Driban JB, Barr AE, Amin M, et al. Joint inflammation and early degeneration induced by high-force reaching are attenuated by ibuprofen in an animal model of work-related musculoskeletal disorder. J Biomed Biotechnol 2011;2011:Article ID 691412. DOI: 10.1155/2011/691412.
    • (2011) J Biomed Biotechnol , vol.2011
    • Driban, J.B.1    Barr, A.E.2    Amin, M.3
  • 15
    • 0032777468 scopus 로고    scopus 로고
    • Selective cyclooxygenase-2 inhibitors for the treatment of arthritis
    • Fung HB, Kirschenbaum HL. Selective cyclooxygenase-2 inhibitors for the treatment of arthritis. Clin Ther 1999;21:1131-57.
    • (1999) Clin Ther , vol.21 , pp. 1131-1157
    • Fung, H.B.1    Kirschenbaum, H.L.2
  • 16
    • 26844460287 scopus 로고    scopus 로고
    • Is there an association between the use of different types of nonsteroidal antiinflammatory drugs and radiologic progression of osteoarthritis? the Rotterdam Study
    • Reijman M, Bierma-Zeinstra SM, Pols HA, et al. Is there an association between the use of different types of nonsteroidal antiinflammatory drugs and radiologic progression of osteoarthritis? The Rotterdam Study. Arthritis Rheum 2005;52:3137-42.
    • (2005) Arthritis Rheum , vol.52 , pp. 3137-3142
    • Reijman, M.1    Bierma-Zeinstra, S.M.2    Pols, H.A.3
  • 17
    • 55749091798 scopus 로고    scopus 로고
    • Intra-articular depot formulation principles: Role in the management of postoperative pain and arthritic disorders
    • Larsen C, Ostergaard J, Larsen SW, et al. Intra-articular depot formulation principles: role in the management of postoperative pain and arthritic disorders. Int J Pharm 2008;97:4622-54.
    • (2008) Int J Pharm , vol.97 , pp. 4622-4654
    • Larsen, C.1    Ostergaard, J.2    Larsen, S.W.3
  • 18
    • 49449098794 scopus 로고    scopus 로고
    • Synthesis and evaluation of novel polyester-ibuprofen conjugates for modified drug release
    • Thompson CJ, Hansford D, Munday DL, et al. Synthesis and evaluation of novel polyester-ibuprofen conjugates for modified drug release. Drug Dev Ind Pharm 2008;34:877-84.
    • (2008) Drug Dev Ind Pharm , vol.34 , pp. 877-884
    • Thompson, C.J.1    Hansford, D.2    Munday, D.L.3
  • 19
    • 84887248913 scopus 로고    scopus 로고
    • Preparation and irradiation of Pluronic F127-based thermoreversible and mucoadhesive hydrogel for local delivery of naproxen
    • [Epub ahead of print]
    • Shin BK, Baek EJ, Choi SG, et al. Preparation and irradiation of Pluronic F127-based thermoreversible and mucoadhesive hydrogel for local delivery of naproxen. Drug Dev Ind Pharm 2012. [Epub ahead of print]. DOI: 10.3109/036399045.2012.665925.
    • (2012) Drug Dev Ind Pharm
    • Shin, B.K.1    Baek, E.J.2    Choi, S.G.3
  • 20
    • 82455188347 scopus 로고    scopus 로고
    • Design and characterization of sustained release ketoprofen entrapped carnauba wax micro-particles
    • Oliveira RB, Nascimento TL, Lima EM. Design and characterization of sustained release ketoprofen entrapped carnauba wax micro-particles. Drug Dev Ind Pharm 2012;38:1-11.
    • (2012) Drug Dev Ind Pharm , vol.38 , pp. 1-11
    • Oliveira, R.B.1    Nascimento, T.L.2    Lima, E.M.3
  • 21
    • 0017257011 scopus 로고
    • Mason CG Pharmacological differences between the optical isomers of ibuprofen: Evidence for metabolic inversion of the (-)-isomer
    • Adams SS, Bresloff P, Mason CG Pharmacological differences between the optical isomers of ibuprofen: evidence for metabolic inversion of the (-)-isomer. J Pharm Pharmacol 1976;28:256-7.
    • (1976) J Pharm Pharmacol , vol.28 , pp. 256-257
    • Adams, S.S.1    Bresloff, P.2
  • 22
    • 0025790204 scopus 로고
    • S-ibuprofen versus ibuprofen-racemate. A randomized double-blind study in patients with rheumatoid arthritis
    • Stock KP, Geisslinger G, Loew D, et al. S-ibuprofen versus ibuprofen-racemate. A randomized double-blind study in patients with rheumatoid arthritis. Rheumatol Int 1991;11:199-202.
    • (1991) Rheumatol Int , vol.11 , pp. 199-202
    • Stock, K.P.1    Geisslinger, G.2    Loew, D.3
  • 23
    • 0037392752 scopus 로고    scopus 로고
    • Comparison of the efficacy and tolerability of dexibuprofen and celecoxib in the treatment of osteoarthritis of the hip
    • Hawel R, Klein G, Singer F, et al. Comparison of the efficacy and tolerability of dexibuprofen and celecoxib in the treatment of osteoarthritis of the hip. Int J Clin Pharmacol Ther 2003;41: 153-64.
    • (2003) Int J Clin Pharmacol Ther , vol.41 , pp. 153-164
    • Hawel, R.1    Klein, G.2    Singer, F.3
  • 24
    • 33845416419 scopus 로고    scopus 로고
    • "in vitro" differences among (R) and (S) enantiomers of profens in their activities related to articular pathophysiology
    • Panico AM, Cardile V, Gentile B, et al. "In vitro" differences among (R) and (S) enantiomers of profens in their activities related to articular pathophysiology. Inflammation 2005;29:119-28.
    • (2005) Inflammation , vol.29 , pp. 119-128
    • Panico, A.M.1    Cardile, V.2    Gentile, B.3
  • 25
    • 0032923708 scopus 로고    scopus 로고
    • Effects of R and S enantiomers and a racemic mixture of carprofen on the production and release of proteoglycan and prostaglandin E2 from equine chondrocytes and cartilage explants
    • Armstrong S, Lees P. Effects of R and S enantiomers and a racemic mixture of carprofen on the production and release of proteoglycan and prostaglandin E2 from equine chondrocytes and cartilage explants. Am J Vet Res 1999;60:98-104.
    • (1999) Am J Vet Res , vol.60 , pp. 98-104
    • Armstrong, S.1    Lees, P.2
  • 26
    • 0036098426 scopus 로고    scopus 로고
    • Effects of carprofen (R and S enantiomers and racemate) on the production of IL-1, IL-6 and TNF-a by equine chondrocytes and synoviocytes
    • Armstrong S, Lees P. Effects of carprofen (R and S enantiomers and racemate) on the production of IL-1, IL-6 and TNF-a by equine chondrocytes and synoviocytes. J Vet Pharmacol Ther 2002;25: 145-53.
    • (2002) J Vet Pharmacol Ther , vol.25 , pp. 145-153
    • Armstrong, S.1    Lees, P.2
  • 27
    • 82655172482 scopus 로고    scopus 로고
    • In vitro evaluation of (S)-ibuprofen toxicity on joint cells and explants of cartilage and synovial membrane
    • Bédouet L, Pascale F, Bonneau M, et al. In vitro evaluation of (S)-ibuprofen toxicity on joint cells and explants of cartilage and synovial membrane. Toxicol In Vitro 2011;25:1944-52.
    • (2011) Toxicol in Vitro , vol.25 , pp. 1944-1952
    • Bédouet, L.1    Pascale, F.2    Bonneau, M.3
  • 28
    • 0027146692 scopus 로고
    • Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
    • Mitchell JA, Akarasereenont P, Thiemermann C, et al. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci USA 1993;90: 11693-7.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11693-11697
    • Mitchell, J.A.1    Akarasereenont, P.2    Thiemermann, C.3
  • 29
    • 0024421547 scopus 로고
    • Recent findings on the pharmacokinetics of non-steroidal anti-inflammatory drugs in synovial fluid
    • Netter P, Bannwarth B, Royer-Morrot MJ. Recent findings on the pharmacokinetics of non-steroidal anti-inflammatory drugs in synovial fluid. Clin Pharmacokinet 1989;17:145-62.
    • (1989) Clin Pharmacokinet , vol.17 , pp. 145-162
    • Netter, P.1    Bannwarth, B.2    Royer-Morrot, M.J.3
  • 30
    • 0034816925 scopus 로고    scopus 로고
    • Cyclooxygenase-independ-ent actions of cyclooxygenase inhibitors
    • Tegeder I, Pfeilschifter J, Geisslinger G. Cyclooxygenase-independ-ent actions of cyclooxygenase inhibitors. FASEB J 2001;15: 2057-72.
    • (2001) FASEB J , vol.15 , pp. 2057-2072
    • Tegeder, I.1    Pfeilschifter, J.2    Geisslinger, G.3
  • 31
    • 0037674469 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs inhibit nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes independent of cyclooxygenase activity
    • Yoon JB, Kim SJ, Hwang SG, et al. Non-steroidal anti-inflammatory drugs inhibit nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes independent of cyclooxygenase activity. J Biol Chem 2003;278:15319-25.
    • (2003) J Biol Chem , vol.278 , pp. 15319-15325
    • Yoon, J.B.1    Kim, S.J.2    Hwang, S.G.3
  • 32
    • 0017529293 scopus 로고
    • The effect of synovial tissue on the breakdown of articular cartilage in organ culture
    • Fell HB, Jubb RW. The effect of synovial tissue on the breakdown of articular cartilage in organ culture. Arthritis Rheum 1977;20: 1359-71.
    • (1977) Arthritis Rheum , vol.20 , pp. 1359-1371
    • Fell, H.B.1    Jubb, R.W.2
  • 33
    • 69849096828 scopus 로고    scopus 로고
    • Co-culture of mechanically injured cartilage with joint capsule tissue alters chondrocyte expression patterns and increases ADAMTS5 production
    • Lee JH, Fitzgerald JB, DiMicco MA, et al. Co-culture of mechanically injured cartilage with joint capsule tissue alters chondrocyte expression patterns and increases ADAMTS5 production. Arch Biochem Biophys 2009;489:118-26.
    • (2009) Arch Biochem Biophys , vol.489 , pp. 118-126
    • Lee, J.H.1    Fitzgerald, J.B.2    Dimicco, M.A.3
  • 34
    • 69149095632 scopus 로고    scopus 로고
    • Potent inhibition of cartilage biosynthesis by coincubation with joint capsule through an IL-1-independent pathway
    • Patwari P, Lin SN, Kurz B, et al. Potent inhibition of cartilage biosynthesis by coincubation with joint capsule through an IL-1-independent pathway. Scand J Med Sci Sports 2009;19:528-35.
    • (2009) Scand J Med Sci Sports , vol.19 , pp. 528-535
    • Patwari, P.1    Lin, S.N.2    Kurz, B.3
  • 35
    • 0037422394 scopus 로고    scopus 로고
    • Effect of buffer media composition on the solubility and effective permeability coefficient of ibuprofen
    • Levis KA, Lane MA, Corrigan OI. Effect of buffer media composition on the solubility and effective permeability coefficient of ibuprofen. Int J Pharm 2003;253:49-59.
    • (2003) Int J Pharm , vol.253 , pp. 49-59
    • Levis, K.A.1    Lane, M.A.2    Corrigan, O.I.3
  • 36
    • 0022552896 scopus 로고
    • Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue
    • Farndale RW, Buttle DJ, Barrett AJ. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta 1986;883: 173-7.
    • (1986) Biochim Biophys Acta , vol.883 , pp. 173-177
    • Farndale, R.W.1    Buttle, D.J.2    Barrett, A.J.3
  • 37
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-5.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 38
    • 0342546477 scopus 로고    scopus 로고
    • Diclofenac sodium incorporated PLGA (50:50) microspheres: Formulation considerations and in vitro/in vivo evaluation
    • Tunçay M, Calis S, Kas HS, et al. Diclofenac sodium incorporated PLGA (50:50) microspheres: formulation considerations and in vitro/in vivo evaluation. Int J Pharm 2000;195:179-88.
    • (2000) Int J Pharm , vol.195 , pp. 179-188
    • Tunçay, M.1    Calis, S.2    Kas, H.S.3
  • 39
    • 0034977175 scopus 로고    scopus 로고
    • In vitro evaluation and intra-articular administration of biodegradable microspheres containing naproxen sodium
    • Bozdag S, Calis S, Kas HS, et al. In vitro evaluation and intra-articular administration of biodegradable microspheres containing naproxen sodium. J Microencapsul 2001;18:443-56.
    • (2001) J Microencapsul , vol.18 , pp. 443-456
    • Bozdag, S.1    Calis, S.2    Kas, H.S.3
  • 40
    • 34547516520 scopus 로고    scopus 로고
    • Preparation and evaluation of biodegradable flurbiprofen gelatin micro-spheres for intra-articular administration
    • Lu Y, Zhang G, Sun D, Zhong Y. Preparation and evaluation of biodegradable flurbiprofen gelatin micro-spheres for intra-articular administration. J Microencapsul 2007;24:515-24.
    • (2007) J Microencapsul , vol.24 , pp. 515-524
    • Lu, Y.1    Zhang, G.2    Sun, D.3    Zhong, Y.4
  • 41
    • 27744585798 scopus 로고    scopus 로고
    • Albumin microspheres as carriers for the antiarthritic drug celecoxib
    • Thakkar H, Sharma RK, Mishra AK, et al. Albumin microspheres as carriers for the antiarthritic drug celecoxib. AAPS PharmSciTech 2005;6:65-73.
    • (2005) AAPS PharmSciTech , vol.6 , pp. 65-73
    • Thakkar, H.1    Sharma, R.K.2    Mishra, A.K.3
  • 42
    • 3242798076 scopus 로고    scopus 로고
    • Biodegradable ibuprofen-loaded PLGA microspheres for intraarticular administration. Effect of Labrafil addition on release in vitro
    • Fernández-Carballido A, Herrero-Vanrell R, Molina-Martinez IT, Pastoriza P. Biodegradable ibuprofen-loaded PLGA microspheres for intraarticular administration. Effect of Labrafil addition on release in vitro. Int J Pharm 2004;279:33-41.
    • (2004) Int J Pharm , vol.279 , pp. 33-41
    • Fernández-Carballido, A.1    Herrero-Vanrell, R.2    Molina-Martinez, I.T.3    Pastoriza, P.4
  • 44
    • 54249104477 scopus 로고    scopus 로고
    • Nitric oxide in inflammation and pain associated with osteoarthritis
    • Abramson SB. Nitric oxide in inflammation and pain associated with osteoarthritis. Arthritis Res Ther 2008;10:S2.
    • (2008) Arthritis Res Ther , vol.10 , pp. S2
    • Abramson, S.B.1
  • 45
    • 41149093664 scopus 로고    scopus 로고
    • Nitric oxide enhances aggrecan degradation by aggrecanase in response to TNF-alpha but not IL-1beta treatment at a post-transcriptional level in bovine cartilage explants
    • Stevens AL, Wheeler CA, Tannenbaum SR, Grodzinsky AJ. Nitric oxide enhances aggrecan degradation by aggrecanase in response to TNF-alpha but not IL-1beta treatment at a post-transcriptional level in bovine cartilage explants. Osteoarthritis Cartilage 2008;16: 489-97.
    • (2008) Osteoarthritis Cartilage , vol.16 , pp. 489-497
    • Stevens, A.L.1    Wheeler, C.A.2    Tannenbaum, S.R.3    Grodzinsky, A.J.4
  • 46
    • 0033858339 scopus 로고    scopus 로고
    • Glucosamine HCl reduces equine articular cartilage degradation in explant culture
    • Fenton JI, Chlebek-Brown KA, Peters TL, et al. Glucosamine HCl reduces equine articular cartilage degradation in explant culture. Osteoarthritis Cartilage 2000;8:258-65.
    • (2000) Osteoarthritis Cartilage , vol.8 , pp. 258-265
    • Fenton, J.I.1    Chlebek-Brown, K.A.2    Peters, T.L.3
  • 47
    • 38949172431 scopus 로고    scopus 로고
    • Proteomic analysis of the LPS-induced stress response in rat chondrocytes reveals induction of innate immune response components in articular cartilage
    • Haglund L, Bernier SM, Onnerfjord P, Recklies AD. Proteomic analysis of the LPS-induced stress response in rat chondrocytes reveals induction of innate immune response components in articular cartilage. Matrix Biol 2008;27:107-18.
    • (2008) Matrix Biol , vol.27 , pp. 107-118
    • Haglund, L.1    Bernier, S.M.2    Onnerfjord, P.3    Recklies, A.D.4
  • 48
    • 33644552751 scopus 로고    scopus 로고
    • Serum amyloid A isoforms in serum and synovial fluid in horses with lipopolysac-charide-induced arthritis
    • Jacobsen S, Niewold TA, Halling-Thomsen M, et al. Serum amyloid A isoforms in serum and synovial fluid in horses with lipopolysac-charide-induced arthritis. Vet Immunol Immunopathol 2006;110: 325-30.
    • (2006) Vet Immunol Immunopathol , vol.110 , pp. 325-330
    • Jacobsen, S.1    Niewold, T.A.2    Halling-Thomsen, M.3
  • 49
    • 67650074900 scopus 로고    scopus 로고
    • Serum amyloid A protein stimulates CCL20 production in rheumatoid synoviocytes
    • Migita K, Koga T, Torigoshi T, et al. Serum amyloid A protein stimulates CCL20 production in rheumatoid synoviocytes. Rheumatology 2009;48:741-7.
    • (2009) Rheumatology , vol.48 , pp. 741-747
    • Migita, K.1    Koga, T.2    Torigoshi, T.3
  • 50
    • 0032902032 scopus 로고    scopus 로고
    • Ibuprofen: New explanation for an old phenomenon
    • Stuhlmeier KM, Li H, Kao JJ. Ibuprofen: new explanation for an old phenomenon. Biochem Pharmacol 1999;57:313-20.
    • (1999) Biochem Pharmacol , vol.57 , pp. 313-320
    • Stuhlmeier, K.M.1    Li, H.2    Kao, J.J.3
  • 51
    • 33745620058 scopus 로고    scopus 로고
    • Biochemical effects of two different hyaluronic acid products in a co-culture model of osteoarthritis
    • Greenberg DD, Stoker A, Kane S, et al. Biochemical effects of two different hyaluronic acid products in a co-culture model of osteoarthritis. Osteoarthritis Cartilage 2006;14:814-22.
    • (2006) Osteoarthritis Cartilage , vol.14 , pp. 814-822
    • Greenberg, D.D.1    Stoker, A.2    Kane, S.3
  • 52
    • 35148889834 scopus 로고    scopus 로고
    • Development of a high-throughput screening assay based on the 3-dimensional pannus model for rheumatoid arthritis
    • Ibold Y, Frauenschuh S, Kaps C, et al. Development of a high-throughput screening assay based on the 3-dimensional pannus model for rheumatoid arthritis. J Biomol Screen 2007;12:956-65.
    • (2007) J Biomol Screen , vol.12 , pp. 956-965
    • Ibold, Y.1    Frauenschuh, S.2    Kaps, C.3
  • 53
    • 0036064137 scopus 로고    scopus 로고
    • Cyclooxygenase 2-dependent prostaglandin E2 modulates cartilage proteoglycan degradation in human osteoarthritis explants
    • Hardy MM, Seibert K, Manning PT, et al. Cyclooxygenase 2-dependent prostaglandin E2 modulates cartilage proteoglycan degradation in human osteoarthritis explants. Arthritis Rheum 2002;46: 1789-803.
    • (2002) Arthritis Rheum , vol.46 , pp. 1789-1803
    • Hardy, M.M.1    Seibert, K.2    Manning, P.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.