Non-viral endostatin plasmid transfection of mesenchymal stem cells via collagen scaffolds

Biomaterials

Volumn 30, Issue 6, 2009, Pages 1222-1231

  Sun, Xiao Dan ^a,b   Jeng, Lily ^a,c   Bolliet, Catherine ^a   Olsen, Bjorn R ^d   Spector, Myron ^a,e  

^a VA BOSTON HEALTHCARE SYSTEM   (United States)

^b TSINGHUA UNIVERSITY   (China)

^c Massachusetts Institute of Technology Cambridge   (United States)

^d HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Collagen; Endostatin; Scaffold; Stem cells

Indexed keywords

CARTILAGE; CELL CULTURE; CELLS; COLLAGEN; CYTOLOGY; ELECTRON ENERGY LEVELS; FLOWCHARTING; LIGAMENTS; NUCLEIC ACIDS; TISSUE ENGINEERING;

ANGIOGENESIS; ANGIOGENIC FACTORS; ARTICULAR CARTILAGES; CARTILAGE TISSUE ENGINEERINGS; CATIONIC LIPIDS; COLLAGEN SCAFFOLDS; COLLAGEN SPONGES; EARLY STAGES; ENDOSTATIN; HYALINE CARTILAGES; INDEPENDENT VARIABLES; LIPOPLEX; MARROW STROMAL CELLS; MESENCHYMAL STEM CELLS; NAKED PLASMIDS; OVEREXPRESSION; PLASMID ENCODING; PLASMID TRANSFECTIONS; STEM CELLS; TISSUE REGENERATIONS; TRANSFECTED CELLS; VASCULAR NETWORKS; VASCULARIZATION;

SCAFFOLDS;

COLLAGEN TYPE 1; COLLAGEN TYPE 3; ENDOSTATIN; NORLEUCINE;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL GROWTH; CONTROLLED STUDY; ELECTROPHORESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSFECTION; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BIOLOGICAL ASSAY; CELL COUNT; CELL PROLIFERATION; CELLS, CULTURED; CHONDROGENESIS; COLLAGEN; CULTURE MEDIA; DNA; ELECTROPHORESIS, AGAR GEL; ENDOSTATINS; GOATS; MESENCHYMAL STEM CELLS; PLASMIDS; TIME FACTORS; TISSUE SCAFFOLDS; TRANSFECTION;

CAPRA;

EID: 57749186665     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2008.10.020     Document Type: Article

References (46)

1. Shea L.D., Smiley E., Bonadio J., and Mooney D.J. DNA delivery from polymer matrices for tissue engineering. Nature Biotech 17 (1999) 551-554
2. Bonadio J., Smiley E., Patil P., and Goldstein S. Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration. Nat Med 5 (1999) 753-759
3. Samuel R.E., Lee C.R., Ghivizzani S., Evans C.H., Yannas I.V., Olsen B.R., et al. Delivery of plasmid DNA to articular chondrocytes via novel collagen-glycosaminoglycan matrices. Hum Gene Ther 13 (2002) 791-802
4. Lee C.R., Grodzinsky A.J., Hsu H.-P., and Spector M. Effects of a cultured autologous chondrocyte-seeded type II collagen scaffold on the healing of a chondral defect in a canine model. J Orthop Res 21 (2003) 272-281
5. Arnold F., and West D.C. Angiogenesis in wound healing. Pharmacol Therap 52 3 (1991) 407-422
6. Mankin H.J. The response of articular cartilage to mechanical injury. J Bone Joint Surg 64 3 (1982) 460-466
7. Pandya N.M., Dhalla N.S., and Santani D.D. Angiogenesis - a new target for future therapy. Vasc Pharmacol 44 5 (2006) 265-274
8. Moses M.A., Wiederschain D., Wu I., Fernandez C.A., Ghazizadeh V., Lane W.S., et al. Troponin I is present in human cartilage and inhibits angiogenesis. Proc Nat Acad Sci U S A 96 6 (1999) 2645-2650
9. Martel-Pelletier J., McCollum R., Fujimoto N., Obata K., Cloutier J.M., and Pelletier J.P. Excess of metalloproteases over tissue inhibitor of metalloprotease may contribute to cartilage degradation in osteoarthritis and rheumatoid arthritis. Laboratory investigation. J Tech Meth Pathol 70 6 (1994) 807-815
10. Pfander D., Cramer T., Deuerling D., Weseloh G., and Swoboda B. Expression of thrombospondin-1 and its receptor CD36 in human osteoarthritic cartilage. Ann Rheum Dis 59 6 (2000) 448-454
11. Hiraki Y., Inoue H., Iyama K., Kamizono A., Ochiai M., Shukunami C., et al. Identification of chondromodulin I as a novel endothelial cell growth inhibitor. Purification and its localization in the avascular zone of epiphyseal cartilage. J Biol Chem 272 51 (1997) 32419-32426
12. Lotz M., Moats T., and Villiger P.M. Leukemia inhibitory factor is expressed in cartilage and synovium and can contribute to the pathogenesis of arthritis. J Clin Invest 90 3 (1992) 888-896
13. Gerber H.P., Vu T.H., Ryan A.M., Kowalski J., Werb Z., and Ferrara N. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat Med 5 6 (1999) 623-628
14. Bonnet C.S., and Walsh D.A. Osteoarthritis, angiogenesis and inflammation. Rheumatology (Oxford, Engl) 44 1 (2005) 7-16
15. Fenwick S.A., Gregg P.J., and Rooney P. Osteoarthritic cartilage loses its ability to remain avascular. Osteoarthritis and cartilage/OARS. Osteoarthr Res Soc 7 5 (1999) 441-452
16. Walsh D.A. Angiogenesis in osteoarthritis and spondylosis: successful repair with undesirable outcomes. Curr Opin Rheumatol 16 5 (2004) 609-615
17. Smith J.O., Oreffo R.O., Clarke N.M., and Roach H.I. Changes in the antiangiogenic properties of articular cartilage in osteoarthritis. J Orthop Sci 8 6 (2003) 849-857
18. Walsh D.A., and Haywood L. Angiogenesis: a therapeutic target in arthritis. Curr Opin Investig Drugs 2 8 (2001) 1054-1063
19. O'Reilly M.S., Boehm T., Shing Y., Fukai N., Vasios G., Lane W.S., et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 88 (1997) 277-285
20. Folkman J. Antiangiogenesis in cancer therapy - endostatin and its mechanisms of action. Exp Cell Res 312 5 (2006) 594-607
21. Boehm T., Folkman J., Browder T., and O'Reilly M.S. Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature 390 (1997) 404-407
22. Taddei L., Chiarugi P., Brogelli L., Cirri P., Magnelli L., Raugei G., et al. Inhibitory effect of full-length human endostatin on in vitro angiogenesis. Biochem Biophys Res Commun 263 2 (1999) 340-345
23. Pufe T., Petersen W.J., Miosge N., Goldring M.B., Mentlein R., Varoga D.J., et al. Endostatin/collagen XVIII - an inhibitor of angiogenesis - is expressed in cartilage and fibrocartilage. Matrix Biol 23 5 (2004) 267-276
24. Feng Y., Wu Y.P., Zhu X.D., Zhang Y.H., and Ma Q.J. Endostatin promotes the anabolic program of rabbit chondrocyte. Cell Res 15 3 (2005) 201-206
25. Sipola A., Ilvesaro J., Birr E., Jalovaara P., Pettersson R.F., Stenback F., et al. Endostatin inhibits endochondral ossification. J Gene Med 9 12 (2007) 1057-1064
26. Breinan H.A., Martin S.D., Hsu H.-P., and Spector M. Healing of canine articular cartilage defects treated with microfracture, a type II collagen matrix, or cultured autologous chondrocytes. J Orthop Res 18 (2000) 781-789
27. Capito R.M., and Spector M. Collagen scaffolds for nonviral IGF-1 gene delivery in articular cartilage tissue engineering. Gene Ther 14 9 (2007) 721-732
28. Johnstone B., Hering T.M., Caplan A.I., Goldberg V.M., and Yoo J.U. In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells. Exp Cell Res 238 1 (1998) 265-272
29. Yamaguchi N., Anand-Apte B., Lee M., Sasaki T., Fukai N., Shapiro R., et al. Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc-binding. EMBO J 18 (1999) 4414-4423
30. Szary J., and Szala S. Intra-tumoral administration of naked plasmid DNA encoding mouse endostatin inhibits renal carcinoma growth. Int J Cancer 91 6 (2001) 835-839
31. Solchaga L.A., Penick K., Porter J.D., Goldberg V.M., Caplan A.I., and Welter J.F. FGF-2 enhances the mitotic and chondrogenic potentials of human adult bone marrow-derived mesenchymal stem cells. J Cell Physiol 203 2 (2005) 398-409
32. Russlies M., Behrens P., Ehlers E.M., Brohl C., Vindigni C., Spector M., et al. Periosteum stimulates subchondral bone densification in autologous chondrocyte transplantation in a sheep model. Cell Tissue Res 319 1 (2005) 133-142
33. Weadock K., Olson R.M., and Silver F.H. Evaluation of collagen crosslinking techniques. Biomat Med Dev Artif Org 11 4 (1983) 293-318
34. Olde Damink L.H., Dijkstra P.J., van Luyn M.J., van Wachem P.B., Nieuwenhuis P., and Feijen J. Cross-linking of dermal sheep collagen using a water-soluble carbodiimide. Biomaterials 17 8 (1996) 765-773
35. Lee C.R., Grodzinsky A.J., and Spector M. The effects of cross-linking of collagen-glycosaminoglycan scaffolds on compressive stiffness, chondrocyte-mediated contraction, proliferation and biosynthesis. Biomaterials 22 (2001) 3145-3154
36. Kinner B., Zaleskas J.M., and Spector M. Regulation of smooth muscle actin expression and contraction of adult human mesenchymal stem cells. Exp Cell Res 278 (2002) 72-83
37. Vickers S.M., Squitieri L.S., and Spector M. Effects of cross-linking type II collagen-GAG scaffolds on chondrogenesis in vitro: dynamic pore reduction promotes cartilage formation. Tissue Eng 12 5 (2006) 1345-1355
38. Cai D., Marty-Roix R., Hsu H.-P., and Spector M. Lapine and canine bone marrow stromal cells contain smooth muscle actin and contract a collagen-glycosaminoglycan matrix. Tissue Eng 7 (2001) 829-841
39. Kisker O., Becker C.M., Prox D., Fannon M., D'Amato R., Flynn E., et al. Continuous administration of endostatin by intraperitoneally implanted osmotic pump improves the efficacy and potency of therapy in a mouse xenograft tumor model. Cancer Res 61 20 (2001) 7669-7674
40. Dass C.R. Cytotoxicity issues pertinent to lipoplex-mediated gene therapy in-vivo. J Pharm Pharmacol 54 5 (2002) 593-601
41. Kamstock D., Guth A., Elmslie R., Kurzman I., Liggitt D., Coro L., et al. Liposome-DNA complexes infused intravenously inhibit tumor angiogenesis and elicit antitumor activity in dogs with soft tissue sarcoma. Cancer Gene Ther 13 3 (2006) 306-317
42. Li L., Liu R.Y., Huang J.L., Liu Q.C., Li Y., Wu P.H., et al. Adenovirus-mediated intra-tumoral delivery of the human endostatin gene inhibits tumor growth in nasopharyngeal carcinoma. Int J Cancer 118 8 (2006) 2064-2071
43. Kulke M.H., Bergsland E.K., Ryan D.P., Enzinger P.C., Lynch T.J., Zhu A.X., et al. Phase II study of recombinant human endostatin in patients with advanced neuroendocrine tumors. J Clin Oncol 24 22 (2006) 3555-3561
44. Tjin Tham Sjin R.M., Naspinski J., Birsner A.E., Li C., Chan R., Lo K.M., et al. Endostatin therapy reveals a U-shaped curve for antitumor activity. Cancer Gene Ther 13 6 (2006) 619-627
45. Eisterer W., Jiang X., Bachelot T., Pawliuk R., Abramovich C., Leboulch P., et al. Unfulfilled promise of endostatin in a gene therapy-xenotransplant model of human acute lymphocytic leukemia. Mol Ther 5 4 (2002) 352-359
46. Celik I., Surucu O., Dietz C., Heymach J.V., Force J., Hoschele I., et al. Therapeutic efficacy of endostatin exhibits a biphasic dose-response curve. Cancer Res 65 23 (2005) 11044-11050