The effect of molecular weight on hyaluronan's cartilage boundary lubricating ability - alone and in combination with proteoglycan 4

Osteoarthritis and Cartilage

Volumn 19, Issue 11, 2011, Pages 1356-1362

  Kwiecinski, J J ^a   Dorosz, S G ^a   Ludwig, T E ^a   Abubacker, S ^a   Cowman, M K ^b   Schmidt, T A ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b POLYTECHNIC UNIVERSITY   (United States)

Author keywords

Cartilage boundary lubrication; Hyaluronan; Proteoglycan 4 (PRG4)

Indexed keywords

HYALURONIC ACID; PROTEOGLYCAN;

ANIMAL TISSUE; ARTICLE; CARTILAGE; CONTROLLED STUDY; CORRELATION ANALYSIS; FRICTION; GEL MOBILITY SHIFT ASSAY; LUBRICATION; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; SYNOVIAL FLUID;

ANIMALS; CARTILAGE, ARTICULAR; CATTLE; DRUG THERAPY, COMBINATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FRICTION; HYALURONIC ACID; MOLECULAR WEIGHT; PROTEOGLYCANS; STIFLE; VISCOSUPPLEMENTS;

EID: 80053624903     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2011.07.019     Document Type: Article

References (35)

1. Ateshian G.A., Mow V.C. Friction, lubrication, and wear of articular cartilage and diarthrodial joints. Basic Orthopaedic Biomechanics and Mechano-Biology 2005, 447-494. Lippincott Williams & Wilkins, Philadelphia. V.C. Mow, R. Huiskes (Eds.).
2. Balazs E.A., GIbbs D.A. The rheological properties and biological function and hyaluronic acid. Chemistry and Molecular Biology of the Intercellular Matrix 1970, 1241-1254. Academic Press, London, UK. E.A. Balazs (Ed.).
3. Gomez J.E., Thurston G.B. Comparisons of the oscillatory shear viscoelasticity and composition of pathological synovial fluids. Biorheology 1993, 30:409-427.
4. Whiting W., Zernicke R. Biomechanics of Musculoskeletal Injury 2008, Human Kinetics, Champaign, IL.
5. Schmidt T.A., Sah R.L. Effect of synovial fluid on boundary lubrication of articular cartilage. Osteoarthritis Cartilage 2007, 15:35-47.
6. Watterson J.R., Esdaile J.M. Viscosupplementation: therapeutic mechanisms and clinical potential in osteoarthritis of the knee. J Am Acad Orthop Surg 2000, 8:277-284.
7. Mazzucco D., Scott R., Spector M. Composition of joint fluid in patients undergoing total knee replacement and revision arthroplasty: correlation with flow properties. Biomaterials 2004, 25:4433-4445.
8. Laurent T.C., Ryan M., Pietruszkiewicz A. Fractionation of hyaluronic acid. The polydispersity of hyaluronic acid from the bovine vitreous body. Biochim Biophys Acta 1960, 42:476-485.
9. Ghosh P. The role of hyaluronic acid (hyaluronan) in health and disease: interactions with cells, cartilage and components of synovial fluid. Clin Exp Rheumatol 1994, 12:75-82.
10. Schmidt T.A., Gastelum N.S., Nguyen Q.T., Schumacher B.L., Sah R.L. Boundary lubrication of articular cartilage: role of synovial fluid constituents. Arthritis Rheum 2007, 56:882-891.
11. Fam H., Bryant J.T., Kontopoulou M. Rheological properties of synovial fluids. Biorheology 2007, 44:59-74.
12. Dahl L.B., Dahl I.M., Engstrom-Laurent A., Granath K. Concentration and molecular weight of sodium hyaluronate in synovial fluid from patients with rheumatoid arthritis and other arthropathies. Ann Rheum Dis 1985, 44:817-822.
13. Balazs E.A., Watson D., Duff I.F., Roseman S. Hyaluronic acid in synovial fluid. I. Molecular parameters of hyaluronic acid in normal and arthritis human fluids. Arthritis Rheum 1967, 10:357-376.
14. Waddell D.D., Marino A.A. Chronic knee effusions in patients with advanced osteoarthritis: implications for functional outcome of viscosupplementation. J Knee Surg 2007, 20:181-184.
15. Balazs E.A. Analgesic effect of elastoviscous hyaluronan solutions and the treatment of arthritic pain. Cells Tissues Organs 2003, 174:49-62.
16. Balazs E.A. Viscosupplementation for treatment of osteoarthritis: from initial discovery to current status and results. Surg Technol Int 2004, 12:278-289.
17. Goldberg V.M., Buckwalter J.A. Hyaluronans in the treatment of osteoarthritis of the knee: evidence for disease-modifying activity. Osteoarthritis Cartilage 2005, 13:216-224.
18. Ikegawa S., Sano M., Koshizuka Y., Nakamura Y. Isolation, characterization and mapping of the mouse and human PRG4 (proteoglycan 4) genes. Cytogenet Cell Genet 2000, 90:291-297.
19. Swann D.A., Silver F.H., Slayter H.S., Stafford W., Shore E. The molecular structure and lubricating activity of lubricin isolated from bovine and human synovial fluids. Biochem J 1985, 225:195-201.
20. Schumacher B.L., Block J.A., Schmid T.M., Aydelotte M.B., Kuettner K.E. A novel proteoglycan synthesized and secreted by chondrocytes of the superficial zone of articular cartilage. Arch Biochem Biophys 1994, 311:144-152.
21. Jay G.D. Characterization of a bovine synovial fluid lubricating factor. I. Chemical, surface activity and lubricating properties. Connect Tissue Res 1992, 28:71-88.
22. Jay G.D. Lubricin and surfacing of articular joints. Curr Opin Orthop 2004, 15:355-359.
23. Jay G.D., Lane B.P., Sokoloff L. Characterization of a bovine synovial fluid lubricating factor III. The interaction with hyaluronic acid. Connect Tissue Res 1992, 28:245-255.
24. Schmid T., Homandberg G., Madsen L., Su J., Kuettner K. Superficial zone protein (SZP) binds to macromolecules in the lamina splendens of articular cartilage. Trans Orthop Res Soc 2002, 27:359.
25. Chang D.P., Abu-Lail N.I., Guilak F., Jay G.D., Zauscher S. Conformational mechanics, adsorption, and normal force interactions of lubricin and hyaluronic acid on model surfaces. Langmuir 2008, 24:1183-1193.
26. Greene G.W., Banquy X., Lee D.W., Lowrey D.D., Yu J., Israelachvili J.N. Adaptive mechanically controlled lubrication mechanism found in articular joints. Proc Natl Acad Sci U S A 2011, 108:5255-5259.
27. Jay G.D., Torres J.R., Warman M.L., Laderer M.C., Breuer K.S. The role of lubricin in the mechanical behavior of synovial fluid. Proc Natl Acad Sci U S A 2007, 104:6194-6199.
28. Hellman L.M., Fried M.G. Electrophoretic mobility shift assay (EMSA) for detecting protein-nucleic acid interactions. Nat Protoc 2007, 2:1849-1861.
29. Schmidt T.A., Plaas A.H., Sandy J.D. Disulfide-bonded multimers of proteoglycan 4 (PRG4) are present in normal synovial fluids. Biochim Biophys Acta 2009, 1790:375-384.
30. Lee H.G., Cowman M.K. An agarose gel electrophoretic method for analysis of hyaluronan molecular weight distribution. Anal Biochem 1994, 219:278-287.
31. Bhushan B. Introduction to Tribology 2002, Wiley.
32. Alvarez M.C., Kooyman J., Schmidt T.A. Synthesis of proteoglycan 4 (PRG4) disulfide-bonded multimers by chondrocytes in cartilage explants. Trans Orthop Res Soc 2010, 56:850.
33. Antonacci J.M., Cai M.Z., Beeman S.M., Schumacher B.L., Chen A.C., McIlwraith C.W., et al. Mechanisms of articular cartilage lubrication by hyaluronan: effects of concentration and molecular weight. Trans Orthop Res Soc 2011, 36:2138.
34. Cowman M.K., Matsuoka S. Experimental approaches to hyaluronan structure. Carbohydr Res 2005, 340:791-809.
35. Raynal B.D., Hardingham T.E., Thornton D.J., Sheehan J.K. Concentrated solutions of salivary MUC5B mucin do not replicate the gel-forming properties of saliva. Biochem J 2002, 362:289-296.