Decoding the oxidative stress hypothesis in diabetic embryopathy through proapoptotic kinase signaling

American Journal of Obstetrics and Gynecology

Volumn 212, Issue 5, 2015, Pages 569-579

  Yang, Peixin ^a   Albert Reece, E ^a   Wang, Fang ^a   Gabbay Benziv, Rinat ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis signal regulating; embryopathy endoplasmic; hypothesis proapoptotic; kinase 1 c Jun N terminal; kinase 1 2 diabetic; kinase C; kinase signaling protein; neural tube defects; oxidative stress; reticulum stress

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; CASPASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTRANSFERASE; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C DELTA; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; PROTEIN KINASE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ASK1 GENE; CONGENITAL HEART MALFORMATION; CONGENITAL MALFORMATION; EMBRYO; EMBRYOPATHY; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GENE DELETION; HUMAN; HYPERGLYCEMIA; JNK1 GENE; JNK2 GENE; MATERNAL AGE; MATERNAL DIABETES MELLITUS; NEURAL TUBE DEFECT; NONHUMAN; OXIDATIVE STRESS; PREGNANCY COMPLICATION; PRIORITY JOURNAL; PRKC GENE; REVIEW; RODENT MODEL; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; UNITED STATES; EMBRYOLOGY; FEMALE; METABOLISM; PREGNANCY; PREGNANCY DIABETES MELLITUS;

APOPTOSIS; ENDOPLASMIC RETICULUM STRESS; FEMALE; HEART DEFECTS, CONGENITAL; HUMANS; HYPERGLYCEMIA; NEURAL TUBE DEFECTS; OXIDATIVE STRESS; PREGNANCY; PREGNANCY IN DIABETICS; PROTEIN KINASES; SIGNAL TRANSDUCTION;

EID: 84928829130     PISSN: 00029378     EISSN: 10976868     Source Type: Journal    
DOI: 10.1016/j.ajog.2014.11.036     Document Type: Review

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