Synchronization of the factors critical for diabetic teratogenesis: An in vitro model

American Journal of Obstetrics and Gynecology

Volumn 174, Issue 4, 1996, Pages 1284-1288

  Reece, E A ^a   Wiznitzer, A ^a   Homko, C J ^a   Hagay, Z ^a   Ying King Wu, ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Diabetic embryopathy; rat embryo culture

Indexed keywords

GLUCOSE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; EMBRYO; EMBRYO DEVELOPMENT; EMBRYOPATHY; GESTATIONAL AGE; HYPERGLYCEMIA; NIDATION; NONHUMAN; PRIORITY JOURNAL; RAT; TERATOGENESIS; YOLK SAC;

EID: 0029971243     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9378(96)70672-5     Document Type: Article

References (24)

1. JL Kitzmiller JP Cloherty MD Younger Diabetic pregnancy and perinatal morbidity AM J OBSTET GYNECOL 131 1978 560 580
2. J. Pedersen The pregnant diabetic and her newborn 2nd ed 1977 Munksgaard Copenhagen
3. SG Gabbe JH Mestman RK Freeman Management and outcome of pregnancy in diabetes mellitus, classes B to R AM J OBSTET GYNECOL 1298 1977 723 732
4. JL Kitzmiller LA Gavin GD Gin Preconception care of diabetes: glycemic control prevents congenital malformations JAMA 265 1991 731 736
5. WE Horton Jr TW. Sadler Effects of maternal diabetes on early embryogenies: alterations in morphogenesis produced by the ketone body, beta-hydroxybutyrate Diabetes 32 1983 610
6. J. Mills Malformations in infants of diabetic mothers Teratology 25 1982 385 394
7. H Kalter J. Warkany Congenital malformations: etiologic factors and their role in prevention N Engl J Med 308 1983 424 431
8. E Pinter EA Reece CZ Leranth Arachidonic acid prevents hyperglycemia-associated yolk sac damage and embryopathy AM J OBSTET GYNECOL 155 1986 691 702
9. E Pinter EA Reece PL Ogburn Jr Fatty acid content of yolk sac and embryo in hyperglycemia-induced embryopathy and effect of arachidonic acid supplementation AM J OBSTET GYNECOL 159 1986 1484 1490
10. EA Reece CJ Homko Y-K Wu A. Wiznitzer Metabolic fuel mixtures and diabetic embryopathy Clin Perinatol 20 1993 1 17
11. EA Reece E Pinter CZ Leranth Ultrastructural analysis of malformations of the embryonic neural axis induced by in vitro hyperglycemic conditions Teratology 32 1985 363 373
12. N Freinkel NJ Lewis S Akazawa The honeybee syndrome: implications of the teratogenicity of mannose in rat embryo culture N Engl J Med 310 1984 223 230
13. New DAT. Whole-embryo culture and the study of mammalian embryos during organogenesis Biol Rev 53 1987 81 122
14. MK Sanyal F. Naftolin In vitro development of the mammalian embryo J Exp Zool 228 1983 235 251
15. K Fuhrmann H Reiher K Semmler Prevention of congenital malformations in infants of insulin-dependent diabetic mothers Diabetes Care 6 1983 219 223
16. JA Goldman D Dicker Feldberg Pregnancy outcome in patients with insulin-dependent diabetes mellitus with preconceptional diabetic control: a comparative study AM J OBSTET GYNECOL 155 1986 293 297
17. JL Kitzmiller LA Gavin GD Gin Preconception care of diabetes: glycemic control prevents congenital malformations JAMA 265 1991 731 736
18. 1c and risk of major malformation and spontaneous abortion in diabetic pregnancy Teratology 39 1989 225 231
19. NJ Lewis S Akazawa N. Freinkel Teratogenesis from beta-hydroxybutyrate during organogenesis in rat embryo organ culture and enhancement by subteratogenic glucose Diabetes 32 suppl 2 1983 11A
20. N Freinkel DL Cockroft NJ Lewis The 1986 McCollum Award Lecture. Fuel-medicated teratogenesis during early organogenesis: the effects of increased concentrations of glucose, ketones, or somatomedin inhibitor during rat embryo culture Am J Clin Nutr 44 1986 986 995
21. UJ Eirksson LAH Borg H Forsberg J. Styrud Diabetic embryopathy: studies with animal and in vitro models Diabetes 40 suppl 2 1991 94 98
22. N. Freinkel Diabetic embryopathy and fuel-mediated organ teratogenesis: lessons from animal models Horm Metab Res 20 1988 463 475
23. TW Sadler ES Hunter RE Wynn LS. Phillips Evidence for multifactorial origin of diabetes-induced embryopathies Diabetes 38 1989 70 74
24. UF. Eriksson Importance of genetic predisposition and maternal environment for the occurrence of congenital malformations in offspring of diabetic rats Teratology 37 1988 365 374