메뉴 건너뛰기




Volumn 161, Issue 1, 2015, Pages 133-145

Neural control of energy balance: Translating circuits to therapies

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE PLUS NALTREXONE; ANOREXIGENIC AGENT; DEXFENFLURAMINE; EXENDIN 4; FENFLURAMINE; GLUCOSE; INTERMEDIN; LEPTIN RECEPTOR; LIRAGLUTIDE; LORCASERIN; MELANOCORTIN; METFORMIN; METRELEPTIN; PHENTERMINE; PRAMLINTIDE; RIMONABANT; SIBUTRAMINE;

EID: 84925841979     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2015.02.023     Document Type: Review
Times cited : (197)

References (149)
  • 1
    • 84862622024 scopus 로고    scopus 로고
    • FGF21: The center of a transcriptional nexus in metabolic regulation
    • A.C. Adams, and A. Kharitonenkov FGF21: The center of a transcriptional nexus in metabolic regulation Curr. Diabetes Rev. 8 2012 285 293
    • (2012) Curr. Diabetes Rev. , vol.8 , pp. 285-293
    • Adams, A.C.1    Kharitonenkov, A.2
  • 4
    • 79951992387 scopus 로고    scopus 로고
    • AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training
    • Y. Aponte, D. Atasoy, and S.M. Sternson AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training Nat. Neurosci. 14 2011 351 355
    • (2011) Nat. Neurosci. , vol.14 , pp. 351-355
    • Aponte, Y.1    Atasoy, D.2    Sternson, S.M.3
  • 7
  • 8
    • 84864711337 scopus 로고    scopus 로고
    • Deconstruction of a neural circuit for hunger
    • D. Atasoy, J.N. Betley, H.H. Su, and S.M. Sternson Deconstruction of a neural circuit for hunger Nature 488 2012 172 177
    • (2012) Nature , vol.488 , pp. 172-177
    • Atasoy, D.1    Betley, J.N.2    Su, H.H.3    Sternson, S.M.4
  • 9
    • 0034611681 scopus 로고    scopus 로고
    • Genetics of body-weight regulation
    • G.S. Barsh, I.S. Farooqi, and S. O'Rahilly Genetics of body-weight regulation Nature 404 2000 644 651
    • (2000) Nature , vol.404 , pp. 644-651
    • Barsh, G.S.1    Farooqi, I.S.2    O'Rahilly, S.3
  • 10
    • 84908152559 scopus 로고    scopus 로고
    • Neural innervation of white adipose tissue and the control of lipolysis
    • T.J. Bartness, Y. Liu, Y.B. Shrestha, and V. Ryu Neural innervation of white adipose tissue and the control of lipolysis Front. Neuroendocrinol. 35 2014 473 493
    • (2014) Front. Neuroendocrinol. , vol.35 , pp. 473-493
    • Bartness, T.J.1    Liu, Y.2    Shrestha, Y.B.3    Ryu, V.4
  • 13
    • 0034695176 scopus 로고    scopus 로고
    • Functional and chemical anatomy of the afferent vagal system
    • H.R. Berthoud, and W.L. Neuhuber Functional and chemical anatomy of the afferent vagal system Auton. Neurosci. 85 2000 1 17
    • (2000) Auton. Neurosci. , vol.85 , pp. 1-17
    • Berthoud, H.R.1    Neuhuber, W.L.2
  • 14
    • 65549143180 scopus 로고    scopus 로고
    • Transcranial direct current stimulation: a novel approach to control hyperphagia in Prader-Willi syndrome
    • P.S. Boggio, E.C. de Macedo, J.S. Schwartzman, D. Brunoni, M.C. Teixeira, and F. Fregni Transcranial direct current stimulation: a novel approach to control hyperphagia in Prader-Willi syndrome J. Child Neurol. 24 2009 642 643
    • (2009) J. Child Neurol. , vol.24 , pp. 642-643
    • Boggio, P.S.1    De Macedo, E.C.2    Schwartzman, J.S.3    Brunoni, D.4    Teixeira, M.C.5    Fregni, F.6
  • 16
    • 32944470975 scopus 로고    scopus 로고
    • Progressive rise in gut hormone levels after Roux-en-Y gastric bypass suggests gut adaptation and explains altered satiety
    • C.M. Borg, C.W. le Roux, M.A. Ghatei, S.R. Bloom, A.G. Patel, and S.J. Aylwin Progressive rise in gut hormone levels after Roux-en-Y gastric bypass suggests gut adaptation and explains altered satiety Br. J. Surg. 93 2006 210 215
    • (2006) Br. J. Surg. , vol.93 , pp. 210-215
    • Borg, C.M.1    Le Roux, C.W.2    Ghatei, M.A.3    Bloom, S.R.4    Patel, A.G.5    Aylwin, S.J.6
  • 17
    • 68849113147 scopus 로고    scopus 로고
    • Medications for obesity: mechanisms and applications
    • G.A. Bray Medications for obesity: mechanisms and applications Clin. Chest Med. 30 2009 525 538, ix
    • (2009) Clin. Chest Med. , vol.30 , pp. 525-538
    • Bray, G.A.1
  • 18
    • 84910003856 scopus 로고    scopus 로고
    • Medical treatment of obesity: the past, the present and the future
    • G.A. Bray Medical treatment of obesity: the past, the present and the future Best Pract. Res. Clin. Gastroenterol. 28 2014 665 684
    • (2014) Best Pract. Res. Clin. Gastroenterol. , vol.28 , pp. 665-684
    • Bray, G.A.1
  • 19
    • 84876969173 scopus 로고    scopus 로고
    • Roux-en-Y gastric bypass reverses the effects of diet-induced obesity to inhibit the responsiveness of central vagal motoneurones
    • K.N. Browning, S.R. Fortna, and A. Hajnal Roux-en-Y gastric bypass reverses the effects of diet-induced obesity to inhibit the responsiveness of central vagal motoneurones J. Physiol. 591 2013 2357 2372
    • (2013) J. Physiol. , vol.591 , pp. 2357-2372
    • Browning, K.N.1    Fortna, S.R.2    Hajnal, A.3
  • 21
    • 84925522178 scopus 로고    scopus 로고
    • Revisional metabolic/bariatric surgery: a moral obligation
    • H. Buchwald Revisional metabolic/bariatric surgery: a moral obligation Obes. Surg. 25 2014 547 549
    • (2014) Obes. Surg. , vol.25 , pp. 547-549
    • Buchwald, H.1
  • 24
    • 0021248888 scopus 로고
    • Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats
    • J.T. Clark, P.S. Kalra, W.R. Crowley, and S.P. Kalra Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats Endocrinology 115 1984 427 429
    • (1984) Endocrinology , vol.115 , pp. 427-429
    • Clark, J.T.1    Kalra, P.S.2    Crowley, W.R.3    Kalra, S.P.4
  • 26
    • 84884492035 scopus 로고    scopus 로고
    • European drugs agency clashes with scientists over safety of GLP-1 drugs
    • D. Cohen European drugs agency clashes with scientists over safety of GLP-1 drugs BMJ 347 2013 f4838
    • (2013) BMJ , vol.347
    • Cohen, D.1
  • 28
    • 17844401704 scopus 로고    scopus 로고
    • Anatomy and regulation of the central melanocortin system
    • R.D. Cone Anatomy and regulation of the central melanocortin system Nat. Neurosci. 8 2005 571 578
    • (2005) Nat. Neurosci. , vol.8 , pp. 571-578
    • Cone, R.D.1
  • 30
    • 0030160429 scopus 로고    scopus 로고
    • Leptin in humans: current progress and future directions
    • R.V. Considine, and J.F. Caro Leptin in humans: current progress and future directions Clin. Chem. 42 1996 843 844
    • (1996) Clin. Chem. , vol.42 , pp. 843-844
    • Considine, R.V.1    Caro, J.F.2
  • 31
  • 32
    • 82255169467 scopus 로고    scopus 로고
    • Transplanted hypothalamic neurons restore leptin signaling and ameliorate obesity in db/db mice
    • A. Czupryn, Y.D. Zhou, X. Chen, D. McNay, M.P. Anderson, J.S. Flier, and J.D. Macklis Transplanted hypothalamic neurons restore leptin signaling and ameliorate obesity in db/db mice Science 334 2011 1133 1137
    • (2011) Science , vol.334 , pp. 1133-1137
    • Czupryn, A.1    Zhou, Y.D.2    Chen, X.3    McNay, D.4    Anderson, M.P.5    Flier, J.S.6    Macklis, J.D.7
  • 34
    • 84879684058 scopus 로고    scopus 로고
    • Noninvasive brain stimulation: from physiology to network dynamics and back
    • E. Dayan, N. Censor, E.R. Buch, M. Sandrini, and L.G. Cohen Noninvasive brain stimulation: from physiology to network dynamics and back Nat. Neurosci. 16 2013 838 844
    • (2013) Nat. Neurosci. , vol.16 , pp. 838-844
    • Dayan, E.1    Censor, N.2    Buch, E.R.3    Sandrini, M.4    Cohen, L.G.5
  • 35
    • 79959212036 scopus 로고    scopus 로고
    • Vagal afferent neurons in high fat diet-induced obesity; intestinal microflora, gut inflammation and cholecystokinin
    • G. de Lartigue, C.B. de La Serre, and H.E. Raybould Vagal afferent neurons in high fat diet-induced obesity; intestinal microflora, gut inflammation and cholecystokinin Physiol. Behav. 105 2011 100 105
    • (2011) Physiol. Behav. , vol.105 , pp. 100-105
    • De Lartigue, G.1    De La Serre, C.B.2    Raybould, H.E.3
  • 36
    • 84861615371 scopus 로고    scopus 로고
    • Optogenetics and psychiatry: applications, challenges, and opportunities
    • K. Deisseroth Optogenetics and psychiatry: applications, challenges, and opportunities Biol. Psychiatry 71 2012 1030 1032
    • (2012) Biol. Psychiatry , vol.71 , pp. 1030-1032
    • Deisseroth, K.1
  • 38
    • 0034857141 scopus 로고    scopus 로고
    • Development of glucagon-like peptide-1-based pharmaceuticals as therapeutic agents for the treatment of diabetes
    • D.J. Drucker Development of glucagon-like peptide-1-based pharmaceuticals as therapeutic agents for the treatment of diabetes Curr. Pharm. Des. 7 2001 1399 1412
    • (2001) Curr. Pharm. Des. , vol.7 , pp. 1399-1412
    • Drucker, D.J.1
  • 39
    • 33644618433 scopus 로고    scopus 로고
    • The biology of incretin hormones
    • D.J. Drucker The biology of incretin hormones Cell Metab. 3 2006 153 165
    • (2006) Cell Metab. , vol.3 , pp. 153-165
    • Drucker, D.J.1
  • 40
    • 84876227647 scopus 로고    scopus 로고
    • Drug discovery: a jump-start for electroceuticals
    • K. Famm, B. Litt, K.J. Tracey, E.S. Boyden, and M. Slaoui Drug discovery: a jump-start for electroceuticals Nature 496 2013 159 161
    • (2013) Nature , vol.496 , pp. 159-161
    • Famm, K.1    Litt, B.2    Tracey, K.J.3    Boyden, E.S.4    Slaoui, M.5
  • 43
    • 0035044397 scopus 로고    scopus 로고
    • The melanocortin melanocyte-stimulating hormone/adrenocorticotropin(4-10) decreases body fat in humans
    • H.L. Fehm, R. Smolnik, W. Kern, G.P. McGregor, U. Bickel, and J. Born The melanocortin melanocyte-stimulating hormone/adrenocorticotropin(4-10) decreases body fat in humans J. Clin. Endocrinol. Metab. 86 2001 1144 1148
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 1144-1148
    • Fehm, H.L.1    Smolnik, R.2    Kern, W.3    McGregor, G.P.4    Bickel, U.5    Born, J.6
  • 48
    • 0031472452 scopus 로고    scopus 로고
    • Efficacy of metformin in type II diabetes: results of a double-blind, placebo-controlled, dose-response trial
    • A.J. Garber, T.G. Duncan, A.M. Goodman, D.J. Mills, and J.L. Rohlf Efficacy of metformin in type II diabetes: results of a double-blind, placebo-controlled, dose-response trial Am. J. Med. 103 1997 491 497
    • (1997) Am. J. Med. , vol.103 , pp. 491-497
    • Garber, A.J.1    Duncan, T.G.2    Goodman, A.M.3    Mills, D.J.4    Rohlf, J.L.5
  • 49
    • 84856388467 scopus 로고    scopus 로고
    • Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study
    • W.T. Garvey, D.H. Ryan, M. Look, K.M. Gadde, D.B. Allison, C.A. Peterson, M. Schwiers, W.W. Day, and C.H. Bowden Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study Am. J. Clin. Nutr. 95 2012 297 308
    • (2012) Am. J. Clin. Nutr. , vol.95 , pp. 297-308
    • Garvey, W.T.1    Ryan, D.H.2    Look, M.3    Gadde, K.M.4    Allison, D.B.5    Peterson, C.A.6    Schwiers, M.7    Day, W.W.8    Bowden, C.H.9
  • 54
    • 84910108559 scopus 로고    scopus 로고
    • Effects of pramlintide in patients with type 2 diabetes mellitus: an analysis using daily insulin dose tertiles
    • K. Herrmann, K. Shan, S.C. Brunell, and S. Chen Effects of pramlintide in patients with type 2 diabetes mellitus: an analysis using daily insulin dose tertiles Endocr. Pract. 20 2014 1070 1075
    • (2014) Endocr. Pract. , vol.20 , pp. 1070-1075
    • Herrmann, K.1    Shan, K.2    Brunell, S.C.3    Chen, S.4
  • 56
    • 84858713174 scopus 로고    scopus 로고
    • Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis
    • K. Hunter, and C. Hölscher Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis BMC Neurosci. 13 2012 33
    • (2012) BMC Neurosci. , vol.13 , pp. 33
    • Hunter, K.1    Hölscher, C.2
  • 58
    • 84904313098 scopus 로고    scopus 로고
    • Investigational drugs in Phase II clinical trials for the treatment of obesity: implications for future development of novel therapies
    • V.M. Jackson, D.A. Price, and P.A. Carpino Investigational drugs in Phase II clinical trials for the treatment of obesity: implications for future development of novel therapies Expert Opin. Investig. Drugs 23 2014 1055 1066
    • (2014) Expert Opin. Investig. Drugs , vol.23 , pp. 1055-1066
    • Jackson, V.M.1    Price, D.A.2    Carpino, P.A.3
  • 59
    • 21344447493 scopus 로고    scopus 로고
    • Long-term efficacy of leptin replacement in patients with generalized lipodystrophy
    • E.D. Javor, E.K. Cochran, C. Musso, J.R. Young, A.M. Depaoli, and P. Gorden Long-term efficacy of leptin replacement in patients with generalized lipodystrophy Diabetes 54 2005 1994 2002
    • (2005) Diabetes , vol.54 , pp. 1994-2002
    • Javor, E.D.1    Cochran, E.K.2    Musso, C.3    Young, J.R.4    Depaoli, A.M.5    Gorden, P.6
  • 60
    • 0036066641 scopus 로고    scopus 로고
    • Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reduces fasting and postprandial glycemia in type 2 diabetes
    • C.B. Juhl, M. Hollingdal, J. Sturis, G. Jakobsen, H. Agerso, J. Veldhuis, N. Porksen, and O. Schmitz Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reduces fasting and postprandial glycemia in type 2 diabetes Diabetes 51 2002 424 429
    • (2002) Diabetes , vol.51 , pp. 424-429
    • Juhl, C.B.1    Hollingdal, M.2    Sturis, J.3    Jakobsen, G.4    Agerso, H.5    Veldhuis, J.6    Porksen, N.7    Schmitz, O.8
  • 63
    • 84873053314 scopus 로고    scopus 로고
    • Chronic treatment with a melanocortin-4 receptor agonist causes weight loss, reduces insulin resistance, and improves cardiovascular function in diet-induced obese rhesus macaques
    • P. Kievit, H. Halem, D.L. Marks, J.Z. Dong, M.M. Glavas, P. Sinnayah, L. Pranger, M.A. Cowley, K.L. Grove, and M.D. Culler Chronic treatment with a melanocortin-4 receptor agonist causes weight loss, reduces insulin resistance, and improves cardiovascular function in diet-induced obese rhesus macaques Diabetes 62 2013 490 497
    • (2013) Diabetes , vol.62 , pp. 490-497
    • Kievit, P.1    Halem, H.2    Marks, D.L.3    Dong, J.Z.4    Glavas, M.M.5    Sinnayah, P.6    Pranger, L.7    Cowley, M.A.8    Grove, K.L.9    Culler, M.D.10
  • 65
    • 84885089652 scopus 로고    scopus 로고
    • Rapid versus delayed stimulation of feeding by the endogenously released AgRP neuron mediators GABA, NPY, and AgRP
    • M.J. Krashes, B.P. Shah, S. Koda, and B.B. Lowell Rapid versus delayed stimulation of feeding by the endogenously released AgRP neuron mediators GABA, NPY, and AgRP Cell Metab. 18 2013 588 595
    • (2013) Cell Metab. , vol.18 , pp. 588-595
    • Krashes, M.J.1    Shah, B.P.2    Koda, S.3    Lowell, B.B.4
  • 72
    • 84900399933 scopus 로고    scopus 로고
    • Physiological mechanisms behind Roux-en-Y gastric bypass surgery
    • T.A. Lutz, and M. Bueter Physiological mechanisms behind Roux-en-Y gastric bypass surgery Dig. Surg. 31 2014 13 24
    • (2014) Dig. Surg. , vol.31 , pp. 13-24
    • Lutz, T.A.1    Bueter, M.2
  • 73
    • 2542451393 scopus 로고    scopus 로고
    • Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211): a 12-week, double-blind, randomized, controlled trial
    • S. Madsbad, O. Schmitz, J. Ranstam, G. Jakobsen, D.R. Matthews, N.N.I.S. Group NN2211-1310 International Study Group Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211): a 12-week, double-blind, randomized, controlled trial Diabetes Care 27 2004 1335 1342
    • (2004) Diabetes Care , vol.27 , pp. 1335-1342
    • Madsbad, S.1    Schmitz, O.2    Ranstam, J.3    Jakobsen, G.4    Matthews, D.R.5
  • 74
    • 79952297237 scopus 로고    scopus 로고
    • Lorcaserin, a 5-HT(2C) receptor agonist, reduces body weight by decreasing energy intake without influencing energy expenditure
    • C.K. Martin, L.M. Redman, J. Zhang, M. Sanchez, C.M. Anderson, S.R. Smith, and E. Ravussin Lorcaserin, a 5-HT(2C) receptor agonist, reduces body weight by decreasing energy intake without influencing energy expenditure J. Clin. Endocrinol. Metab. 96 2011 837 845
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , pp. 837-845
    • Martin, C.K.1    Redman, L.M.2    Zhang, J.3    Sanchez, M.4    Anderson, C.M.5    Smith, S.R.6    Ravussin, E.7
  • 75
    • 0012433202 scopus 로고
    • Differential effects of d-fenfluramine, l-fenfluramine and d-amphetamine on the microstructure of human eating behaviour
    • J. McGuirk, E. Goodall, T. Silverstone, and P. Willner Differential effects of d-fenfluramine, l-fenfluramine and d-amphetamine on the microstructure of human eating behaviour Behav. Pharmacol. 2 1991 113 119
    • (1991) Behav. Pharmacol. , vol.2 , pp. 113-119
    • McGuirk, J.1    Goodall, E.2    Silverstone, T.3    Willner, P.4
  • 76
    • 82155186228 scopus 로고    scopus 로고
    • Prefrontal cortex transcranial direct current stimulation associated with aerobic exercise change aspects of appetite sensation in overweight adults
    • R.A. Montenegro, A.H. Okano, F.A. Cunha, J.L. Gurgel, E.B. Fontes, and P.T. Farinatti Prefrontal cortex transcranial direct current stimulation associated with aerobic exercise change aspects of appetite sensation in overweight adults Appetite 58 2012 333 338
    • (2012) Appetite , vol.58 , pp. 333-338
    • Montenegro, R.A.1    Okano, A.H.2    Cunha, F.A.3    Gurgel, J.L.4    Fontes, E.B.5    Farinatti, P.T.6
  • 78
    • 84869050741 scopus 로고    scopus 로고
    • Central nervous system control of metabolism
    • M.G. Myers Jr., and D.P. Olson Central nervous system control of metabolism Nature 491 2012 357 363
    • (2012) Nature , vol.491 , pp. 357-363
    • Myers, Jr.M.G.1    Olson, D.P.2
  • 79
    • 84913586856 scopus 로고    scopus 로고
    • The browning of white adipose tissue: some burning issues
    • J. Nedergaard, and B. Cannon The browning of white adipose tissue: some burning issues Cell Metab. 20 2014 396 407
    • (2014) Cell Metab. , vol.20 , pp. 396-407
    • Nedergaard, J.1    Cannon, B.2
  • 80
    • 0031721271 scopus 로고    scopus 로고
    • Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene
    • K. Nonogaki, A.M. Strack, M.F. Dallman, and L.H. Tecott Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene Nat. Med. 4 1998 1152 1156
    • (1998) Nat. Med. , vol.4 , pp. 1152-1156
    • Nonogaki, K.1    Strack, A.M.2    Dallman, M.F.3    Tecott, L.H.4
  • 82
    • 0344512367 scopus 로고    scopus 로고
    • Minireview: nutrient sensing and the regulation of insulin action and energy balance
    • S. Obici, and L. Rossetti Minireview: nutrient sensing and the regulation of insulin action and energy balance Endocrinology 144 2003 5172 5178
    • (2003) Endocrinology , vol.144 , pp. 5172-5178
    • Obici, S.1    Rossetti, L.2
  • 84
    • 84876791435 scopus 로고    scopus 로고
    • Increased admission for alcohol dependence after gastric bypass surgery compared with restrictive bariatric surgery
    • M.P. Ostlund, O. Backman, R. Marsk, D. Stockeld, J. Lagergren, F. Rasmussen, and E. Näslund Increased admission for alcohol dependence after gastric bypass surgery compared with restrictive bariatric surgery JAMA Surg. 148 2013 374 377
    • (2013) JAMA Surg. , vol.148 , pp. 374-377
    • Ostlund, M.P.1    Backman, O.2    Marsk, R.3    Stockeld, D.4    Lagergren, J.5    Rasmussen, F.6    Näslund, E.7
  • 88
    • 84901944641 scopus 로고    scopus 로고
    • The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes
    • R.J. Perry, V.T. Samuel, K.F. Petersen, and G.I. Shulman The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes Nature 510 2014 84 91
    • (2014) Nature , vol.510 , pp. 84-91
    • Perry, R.J.1    Samuel, V.T.2    Petersen, K.F.3    Shulman, G.I.4
  • 93
    • 46749099010 scopus 로고    scopus 로고
    • Leptin reverses weight loss-induced changes in regional neural activity responses to visual food stimuli
    • M. Rosenbaum, M. Sy, K. Pavlovich, R.L. Leibel, and J. Hirsch Leptin reverses weight loss-induced changes in regional neural activity responses to visual food stimuli J. Clin. Invest. 118 2008 2583 2591
    • (2008) J. Clin. Invest. , vol.118 , pp. 2583-2591
    • Rosenbaum, M.1    Sy, M.2    Pavlovich, K.3    Leibel, R.L.4    Hirsch, J.5
  • 99
    • 77954277205 scopus 로고    scopus 로고
    • Fibroblast growth factor 21 action in the brain increases energy expenditure and insulin sensitivity in obese rats
    • D.A. Sarruf, J.P. Thaler, G.J. Morton, J. German, J.D. Fischer, K. Ogimoto, and M.W. Schwartz Fibroblast growth factor 21 action in the brain increases energy expenditure and insulin sensitivity in obese rats Diabetes 59 2010 1817 1824
    • (2010) Diabetes , vol.59 , pp. 1817-1824
    • Sarruf, D.A.1    Thaler, J.P.2    Morton, G.J.3    German, J.4    Fischer, J.D.5    Ogimoto, K.6    Schwartz, M.W.7
  • 101
    • 12344277552 scopus 로고    scopus 로고
    • Diabetes, obesity, and the brain
    • M.W. Schwartz, and D. Porte Jr. Diabetes, obesity, and the brain Science 307 2005 375 379
    • (2005) Science , vol.307 , pp. 375-379
    • Schwartz, M.W.1    Porte, Jr.D.2
  • 102
  • 103
    • 79957896911 scopus 로고    scopus 로고
    • Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice
    • M.M. Scott, K.W. Williams, J. Rossi, C.E. Lee, and J.K. Elmquist Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice J. Clin. Invest. 121 2011 2413 2421
    • (2011) J. Clin. Invest. , vol.121 , pp. 2413-2421
    • Scott, M.M.1    Williams, K.W.2    Rossi, J.3    Lee, C.E.4    Elmquist, J.K.5
  • 104
    • 84880401718 scopus 로고    scopus 로고
    • Developmental control of the melanocortin-4 receptor by MRAP2 proteins in zebrafish
    • J.A. Sebag, C. Zhang, P.M. Hinkle, A.M. Bradshaw, and R.D. Cone Developmental control of the melanocortin-4 receptor by MRAP2 proteins in zebrafish Science 341 2013 278 281
    • (2013) Science , vol.341 , pp. 278-281
    • Sebag, J.A.1    Zhang, C.2    Hinkle, P.M.3    Bradshaw, A.M.4    Cone, R.D.5
  • 106
    • 30044442618 scopus 로고    scopus 로고
    • How diabetes went to our heads
    • discussion 49
    • R.J. Seeley, and M. Tschöp How diabetes went to our heads Nat. Med. 12 2006 47 49 discussion 49
    • (2006) Nat. Med. , vol.12 , pp. 47-49
    • Seeley, R.J.1    Tschöp, M.2
  • 108
    • 0033517284 scopus 로고    scopus 로고
    • Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy
    • I. Shimomura, R.E. Hammer, S. Ikemoto, M.S. Brown, and J.L. Goldstein Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy Nature 401 1999 73 76
    • (1999) Nature , vol.401 , pp. 73-76
    • Shimomura, I.1    Hammer, R.E.2    Ikemoto, S.3    Brown, M.S.4    Goldstein, J.L.5
  • 109
    • 84876478299 scopus 로고    scopus 로고
    • Longitudinal assessment of food intake, fecal energy loss, and energy expenditure after Roux-en-Y gastric bypass surgery in high-fat-fed obese rats
    • A.C. Shin, H. Zheng, R.L. Townsend, L.M. Patterson, G.M. Holmes, and H.R. Berthoud Longitudinal assessment of food intake, fecal energy loss, and energy expenditure after Roux-en-Y gastric bypass surgery in high-fat-fed obese rats Obes. Surg. 23 2013 531 540
    • (2013) Obes. Surg. , vol.23 , pp. 531-540
    • Shin, A.C.1    Zheng, H.2    Townsend, R.L.3    Patterson, L.M.4    Holmes, G.M.5    Berthoud, H.R.6
  • 111
    • 63849112609 scopus 로고    scopus 로고
    • Hindbrain leptin stimulation induces anorexia and hyperthermia mediated by hindbrain melanocortin receptors
    • K.P. Skibicka, and H.J. Grill Hindbrain leptin stimulation induces anorexia and hyperthermia mediated by hindbrain melanocortin receptors Endocrinology 150 2009 1705 1711
    • (2009) Endocrinology , vol.150 , pp. 1705-1711
    • Skibicka, K.P.1    Grill, H.J.2
  • 112
    • 77954635020 scopus 로고    scopus 로고
    • Multicenter, placebo-controlled trial of lorcaserin for weight management
    • Behavioral Modification and Lorcaserin for Overweight and Obesity Management (BLOOM) Study Group
    • S.R. Smith, N.J. Weissman, C.M. Anderson, M. Sanchez, E. Chuang, S. Stubbe, H. Bays, W.R. Shanahan, M. Behavioral Behavioral Modification and Lorcaserin for Overweight and Obesity Management (BLOOM) Study Group Multicenter, placebo-controlled trial of lorcaserin for weight management N. Engl. J. Med. 363 2010 245 256
    • (2010) N. Engl. J. Med. , vol.363 , pp. 245-256
    • Smith, S.R.1    Weissman, N.J.2    Anderson, C.M.3    Sanchez, M.4    Chuang, E.5    Stubbe, S.6    Bays, H.7    Shanahan, W.R.8    Behavioral, M.9
  • 114
    • 84911980609 scopus 로고    scopus 로고
    • Response to deep brain stimulation in the lateral hypothalamic area in a rat model of obesity: in vivo assessment of brain glucose metabolism
    • M.L. Soto-Montenegro, J. Pascau, and M. Desco Response to deep brain stimulation in the lateral hypothalamic area in a rat model of obesity: in vivo assessment of brain glucose metabolism Mol. Imaging Biol. 16 2014 830 837
    • (2014) Mol. Imaging Biol. , vol.16 , pp. 830-837
    • Soto-Montenegro, M.L.1    Pascau, J.2    Desco, M.3
  • 118
    • 84857363312 scopus 로고    scopus 로고
    • Alcohol use disorders after bariatric surgery
    • J. Suzuki, F. Haimovici, and G. Chang Alcohol use disorders after bariatric surgery Obes. Surg. 22 2012 201 207
    • (2012) Obes. Surg. , vol.22 , pp. 201-207
    • Suzuki, J.1    Haimovici, F.2    Chang, G.3
  • 119
    • 31944435045 scopus 로고    scopus 로고
    • Effect of Roux-en-Y gastric bypass on satiety and food likes: the role of genetics
    • R.C. Thirlby, F. Bahiraei, J. Randall, and A. Drewnoski Effect of Roux-en-Y gastric bypass on satiety and food likes: the role of genetics J. Gastrointest. Surg. 10 2006 270 277
    • (2006) J. Gastrointest. Surg. , vol.10 , pp. 270-277
    • Thirlby, R.C.1    Bahiraei, F.2    Randall, J.3    Drewnoski, A.4
  • 122
    • 50049119700 scopus 로고    scopus 로고
    • Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice
    • S. Troy, M. Soty, L. Ribeiro, L. Laval, S. Migrenne, X. Fioramonti, B. Pillot, V. Fauveau, R. Aubert, and B. Viollet et al. Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice Cell Metab. 8 2008 201 211
    • (2008) Cell Metab. , vol.8 , pp. 201-211
    • Troy, S.1    Soty, M.2    Ribeiro, L.3    Laval, L.4    Migrenne, S.5    Fioramonti, X.6    Pillot, B.7    Fauveau, V.8    Aubert, R.9    Viollet, B.10
  • 123
    • 84879357075 scopus 로고    scopus 로고
    • Computational modeling of transcranial direct current stimulation (tDCS) in obesity: Impact of head fat and dose guidelines
    • D.Q. Truong, G. Magerowski, G.L. Blackburn, M. Bikson, and M. Alonso-Alonso Computational modeling of transcranial direct current stimulation (tDCS) in obesity: Impact of head fat and dose guidelines Neuroimage Clin 2 2013 759 766
    • (2013) Neuroimage Clin , vol.2 , pp. 759-766
    • Truong, D.Q.1    Magerowski, G.2    Blackburn, G.L.3    Bikson, M.4    Alonso-Alonso, M.5
  • 125
    • 84920828713 scopus 로고    scopus 로고
    • DREADDs (designer receptors exclusively activated by designer drugs): chemogenetic tools with therapeutic utility
    • D.J. Urban, and B.L. Roth DREADDs (designer receptors exclusively activated by designer drugs): chemogenetic tools with therapeutic utility Annu. Rev. Pharmacol. Toxicol. 55 2015 399 417
    • (2015) Annu. Rev. Pharmacol. Toxicol. , vol.55 , pp. 399-417
    • Urban, D.J.1    Roth, B.L.2
  • 126
    • 77956396479 scopus 로고    scopus 로고
    • Chronic vagus nerve stimulation decreased weight gain, food consumption and sweet craving in adult obese minipigs
    • D. Val-Laillet, A. Biraben, G. Randuineau, and C.H. Malbert Chronic vagus nerve stimulation decreased weight gain, food consumption and sweet craving in adult obese minipigs Appetite 55 2010 245 252
    • (2010) Appetite , vol.55 , pp. 245-252
    • Val-Laillet, D.1    Biraben, A.2    Randuineau, G.3    Malbert, C.H.4
  • 130
    • 40849116457 scopus 로고    scopus 로고
    • Synergistic impairment of glucose homeostasis in ob/ob mice lacking functional serotonin 2C receptors
    • J.M. Wade, P. Juneja, A.W. MacKay, J. Graham, P.J. Havel, L.H. Tecott, and E.H. Goulding Synergistic impairment of glucose homeostasis in ob/ob mice lacking functional serotonin 2C receptors Endocrinology 149 2008 955 961
    • (2008) Endocrinology , vol.149 , pp. 955-961
    • Wade, J.M.1    Juneja, P.2    MacKay, A.W.3    Graham, J.4    Havel, P.J.5    Tecott, L.H.6    Goulding, E.H.7
  • 131
    • 84860729198 scopus 로고    scopus 로고
    • Intranasal application of the melanocortin 4 receptor agonist MSH/ACTH(4-10) in humans causes lipolysis in white adipose tissue
    • P. Wellhöner, R. Hörster, F. Jacobs, F. Sayk, H. Lehnert, and C. Dodt Intranasal application of the melanocortin 4 receptor agonist MSH/ACTH(4-10) in humans causes lipolysis in white adipose tissue Int. J. Obes. (Lond.) 36 2012 703 708
    • (2012) Int. J. Obes. (Lond.) , vol.36 , pp. 703-708
    • Wellhöner, P.1    Hörster, R.2    Jacobs, F.3    Sayk, F.4    Lehnert, H.5    Dodt, C.6
  • 132
    • 84879931488 scopus 로고    scopus 로고
    • Lateral hypothalamic area deep brain stimulation for refractory obesity: a pilot study with preliminary data on safety, body weight, and energy metabolism
    • D.M. Whiting, N.D. Tomycz, J. Bailes, L. de Jonge, V. Lecoultre, B. Wilent, D. Alcindor, E.R. Prostko, B.C. Cheng, and C. Angle et al. Lateral hypothalamic area deep brain stimulation for refractory obesity: a pilot study with preliminary data on safety, body weight, and energy metabolism J. Neurosurg. 119 2013 56 63
    • (2013) J. Neurosurg. , vol.119 , pp. 56-63
    • Whiting, D.M.1    Tomycz, N.D.2    Bailes, J.3    De Jonge, L.4    Lecoultre, V.5    Wilent, B.6    Alcindor, D.7    Prostko, E.R.8    Cheng, B.C.9    Angle, C.10
  • 133
    • 33749063364 scopus 로고    scopus 로고
    • Deep brain stimulation for neurologic and neuropsychiatric disorders
    • T. Wichmann, and M.R. Delong Deep brain stimulation for neurologic and neuropsychiatric disorders Neuron 52 2006 197 204
    • (2006) Neuron , vol.52 , pp. 197-204
    • Wichmann, T.1    Delong, M.R.2
  • 134
    • 42149124403 scopus 로고    scopus 로고
    • Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction
    • J.E. Wikberg, and F. Mutulis Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction Nat. Rev. Drug Discov. 7 2008 307 323
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 307-323
    • Wikberg, J.E.1    Mutulis, F.2
  • 137
    • 84879958216 scopus 로고    scopus 로고
    • Acute behavioural effects of bupropion and naltrexone, alone and in combination, in non-deprived male rats presented with palatable mash
    • F.L. Wright, and R.J. Rodgers Acute behavioural effects of bupropion and naltrexone, alone and in combination, in non-deprived male rats presented with palatable mash Psychopharmacology (Berl.) 228 2013 291 307
    • (2013) Psychopharmacology (Berl.) , vol.228 , pp. 291-307
    • Wright, F.L.1    Rodgers, R.J.2
  • 138
    • 67549112681 scopus 로고    scopus 로고
    • Loss of GABAergic signaling by AgRP neurons to the parabrachial nucleus leads to starvation
    • Q. Wu, M.P. Boyle, and R.D. Palmiter Loss of GABAergic signaling by AgRP neurons to the parabrachial nucleus leads to starvation Cell 137 2009 1225 1234
    • (2009) Cell , vol.137 , pp. 1225-1234
    • Wu, Q.1    Boyle, M.P.2    Palmiter, R.D.3
  • 139
    • 84859215897 scopus 로고    scopus 로고
    • Deciphering a neuronal circuit that mediates appetite
    • Q. Wu, M.S. Clark, and R.D. Palmiter Deciphering a neuronal circuit that mediates appetite Nature 483 2012 594 597
    • (2012) Nature , vol.483 , pp. 594-597
    • Wu, Q.1    Clark, M.S.2    Palmiter, R.D.3
  • 144
    • 79959759470 scopus 로고    scopus 로고
    • NPY receptors as potential targets for anti-obesity drug development
    • E. Yulyaningsih, L. Zhang, H. Herzog, and A. Sainsbury NPY receptors as potential targets for anti-obesity drug development Br. J. Pharmacol. 163 2011 1170 1202
    • (2011) Br. J. Pharmacol. , vol.163 , pp. 1170-1202
    • Yulyaningsih, E.1    Zhang, L.2    Herzog, H.3    Sainsbury, A.4
  • 146
    • 84874215150 scopus 로고    scopus 로고
    • Acute and long-term suppression of feeding behavior by POMC neurons in the brainstem and hypothalamus, respectively
    • C. Zhan, J. Zhou, Q. Feng, J.E. Zhang, S. Lin, J. Bao, P. Wu, and M. Luo Acute and long-term suppression of feeding behavior by POMC neurons in the brainstem and hypothalamus, respectively J. Neurosci. 33 2013 3624 3632
    • (2013) J. Neurosci. , vol.33 , pp. 3624-3632
    • Zhan, C.1    Zhou, J.2    Feng, Q.3    Zhang, J.E.4    Lin, S.5    Bao, J.6    Wu, P.7    Luo, M.8
  • 148
    • 42049095675 scopus 로고    scopus 로고
    • Neural systems controlling the drive to eat: mind versus metabolism
    • H. Zheng, and H.R. Berthoud Neural systems controlling the drive to eat: mind versus metabolism Physiology (Bethesda) 23 2008 75 83
    • (2008) Physiology (Bethesda) , vol.23 , pp. 75-83
    • Zheng, H.1    Berthoud, H.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.