메뉴 건너뛰기




Volumn 137, Issue 7, 2009, Pages 1225-1234

Loss of GABAergic Signaling by AgRP Neurons to the Parabrachial Nucleus Leads to Starvation

Author keywords

MOLNEURO

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; AGOUTI RELATED PROTEIN; BRETAZENIL; NEUROPEPTIDE Y; PROTEIN FOS;

EID: 67549112681     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2009.04.022     Document Type: Article
Times cited : (369)

References (50)
  • 2
    • 0029759523 scopus 로고    scopus 로고
    • The lateral hypothalamic area revisited: ingestive behavior
    • Bernardis L.L., and Bellinger L.L. The lateral hypothalamic area revisited: ingestive behavior. Neurosci. Biobehav. Rev. 20 (1996) 189-287
    • (1996) Neurosci. Biobehav. Rev. , vol.20 , pp. 189-287
    • Bernardis, L.L.1    Bellinger, L.L.2
  • 3
    • 0028839001 scopus 로고
    • Benzodiazepines, appetite, and taste palatability
    • Berridge K.C., and Pecina S. Benzodiazepines, appetite, and taste palatability. Neurosci. Biobehav. Rev. 19 (1995) 121-131
    • (1995) Neurosci. Biobehav. Rev. , vol.19 , pp. 121-131
    • Berridge, K.C.1    Pecina, S.2
  • 4
    • 0035851843 scopus 로고    scopus 로고
    • Hypothalamic and vagal neuropeptide circuitries regulating food intake
    • Broberger C., and Hokfelt T. Hypothalamic and vagal neuropeptide circuitries regulating food intake. Physiol. Behav. 74 (2001) 669-682
    • (2001) Physiol. Behav. , vol.74 , pp. 669-682
    • Broberger, C.1    Hokfelt, T.2
  • 5
    • 0032443807 scopus 로고    scopus 로고
    • The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice
    • Broberger C., Johansen J., Johansson C., Schalling M., and Hokfelt T. The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice. Proc. Natl. Acad. Sci. USA 95 (1998) 15043-15048
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 15043-15048
    • Broberger, C.1    Johansen, J.2    Johansson, C.3    Schalling, M.4    Hokfelt, T.5
  • 6
    • 54549120172 scopus 로고    scopus 로고
    • A naloxonazine sensitive (mu1 receptor) mechanism in the parabrachial nucleus modulates eating
    • Chaijale N.N., Aloyo V.J., and Simansky K.J. A naloxonazine sensitive (mu1 receptor) mechanism in the parabrachial nucleus modulates eating. Brain Res. 1240 (2008) 111-118
    • (2008) Brain Res. , vol.1240 , pp. 111-118
    • Chaijale, N.N.1    Aloyo, V.J.2    Simansky, K.J.3
  • 7
    • 34250203570 scopus 로고    scopus 로고
    • GAD67-mediated GABA synthesis and signaling regulate inhibitory synaptic innervation in the visual cortex
    • Chattopadhyaya B., Di C.G., Wu C.Z., Knott G., Kuhlman S., Fu Y., Palmiter R.D., and Huang Z.J. GAD67-mediated GABA synthesis and signaling regulate inhibitory synaptic innervation in the visual cortex. Neuron 54 (2007) 889-903
    • (2007) Neuron , vol.54 , pp. 889-903
    • Chattopadhyaya, B.1    Di, C.G.2    Wu, C.Z.3    Knott, G.4    Kuhlman, S.5    Fu, Y.6    Palmiter, R.D.7    Huang, Z.J.8
  • 8
    • 17844401704 scopus 로고    scopus 로고
    • Anatomy and regulation of the central melanocortin system
    • Cone R.D. Anatomy and regulation of the central melanocortin system. Nat. Neurosci. 8 (2005) 571-578
    • (2005) Nat. Neurosci. , vol.8 , pp. 571-578
    • Cone, R.D.1
  • 9
    • 16244376193 scopus 로고    scopus 로고
    • Palatability-dependent appetite and benzodiazepines: new directions from the pharmacology of GABA(A) receptor subtypes
    • Cooper S.J. Palatability-dependent appetite and benzodiazepines: new directions from the pharmacology of GABA(A) receptor subtypes. Appetite 44 (2005) 133-150
    • (2005) Appetite , vol.44 , pp. 133-150
    • Cooper, S.J.1
  • 11
    • 55749101589 scopus 로고    scopus 로고
    • Activating parabrachial cannabinoid CB1 receptors selectively stimulates feeding of palatable foods in rats
    • DiPatrizio N.V., and Simansky K.J. Activating parabrachial cannabinoid CB1 receptors selectively stimulates feeding of palatable foods in rats. J. Neurosci. 28 (2008) 9702-9709
    • (2008) J. Neurosci. , vol.28 , pp. 9702-9709
    • DiPatrizio, N.V.1    Simansky, K.J.2
  • 12
    • 33746064888 scopus 로고    scopus 로고
    • Enhanced sucrose pellet consumption induced by benzodiazepine-type drugs in squirrel monkeys: role of GABAA receptor subtypes
    • Duke A.N., Platt D.M., Cook J.M., Huang S., Yin W., Mattingly B.A., and Rowlett J.K. Enhanced sucrose pellet consumption induced by benzodiazepine-type drugs in squirrel monkeys: role of GABAA receptor subtypes. Psychopharmacology (Berl.) 187 (2006) 321-330
    • (2006) Psychopharmacology (Berl.) , vol.187 , pp. 321-330
    • Duke, A.N.1    Platt, D.M.2    Cook, J.M.3    Huang, S.4    Yin, W.5    Mattingly, B.A.6    Rowlett, J.K.7
  • 13
    • 34547448292 scopus 로고    scopus 로고
    • The effects of intraperitoneal administration of the GABA(B) receptor agonist baclofen on food intake in CFLP and C57BL/6 mice
    • Ebenezer I.S., and Prabhaker M. The effects of intraperitoneal administration of the GABA(B) receptor agonist baclofen on food intake in CFLP and C57BL/6 mice. Eur. J. Pharmacol. 569 (2007) 90-93
    • (2007) Eur. J. Pharmacol. , vol.569 , pp. 90-93
    • Ebenezer, I.S.1    Prabhaker, M.2
  • 14
    • 0029946644 scopus 로고    scopus 로고
    • Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y
    • Erickson J.C., Clegg K.E., and Palmiter R.D. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature 381 (1996) 415-421
    • (1996) Nature , vol.381 , pp. 415-421
    • Erickson, J.C.1    Clegg, K.E.2    Palmiter, R.D.3
  • 15
    • 33645095699 scopus 로고    scopus 로고
    • AgRP in energy balance: Will the real AgRP please stand up?
    • Flier J.S. AgRP in energy balance: Will the real AgRP please stand up?. Cell Metab. 3 (2006) 83-85
    • (2006) Cell Metab. , vol.3 , pp. 83-85
    • Flier, J.S.1
  • 16
    • 0036814576 scopus 로고    scopus 로고
    • Intravenous flumazenil versus oxazepam tapering in the treatment of benzodiazepine withdrawal: a randomized, placebo-controlled study
    • Gerra G., Zaimovic A., Giusti F., Moi G., and Brewer C. Intravenous flumazenil versus oxazepam tapering in the treatment of benzodiazepine withdrawal: a randomized, placebo-controlled study. Addict. Biol. 7 (2002) 385-395
    • (2002) Addict. Biol. , vol.7 , pp. 385-395
    • Gerra, G.1    Zaimovic, A.2    Giusti, F.3    Moi, G.4    Brewer, C.5
  • 17
    • 0036162117 scopus 로고    scopus 로고
    • The neuroanatomical axis for control of energy balance
    • Grill H.J., and Kaplan J.M. The neuroanatomical axis for control of energy balance. Front. Neuroendocrinol. 23 (2002) 2-40
    • (2002) Front. Neuroendocrinol. , vol.23 , pp. 2-40
    • Grill, H.J.1    Kaplan, J.M.2
  • 19
    • 0032942045 scopus 로고    scopus 로고
    • Characterization of the neuroanatomical distribution of agouti-related protein immunoreactivity in the rhesus monkey and the rat
    • Haskell-Luevano C., Chen P., Li C., Chang K., Smith M.S., Cameron J.L., and Cone R.D. Characterization of the neuroanatomical distribution of agouti-related protein immunoreactivity in the rhesus monkey and the rat. Endocrinology 140 (1999) 1408-1415
    • (1999) Endocrinology , vol.140 , pp. 1408-1415
    • Haskell-Luevano, C.1    Chen, P.2    Li, C.3    Chang, K.4    Smith, M.S.5    Cameron, J.L.6    Cone, R.D.7
  • 21
    • 0030579095 scopus 로고    scopus 로고
    • Hyperphagia induced by direct administration of midazolam into the parabrachial nucleus of the rat
    • Higgs S., and Cooper S.J. Hyperphagia induced by direct administration of midazolam into the parabrachial nucleus of the rat. Eur. J. Pharmacol. 313 (1996) 1-9
    • (1996) Eur. J. Pharmacol. , vol.313 , pp. 1-9
    • Higgs, S.1    Cooper, S.J.2
  • 22
    • 34249293852 scopus 로고    scopus 로고
    • Synaptic plasticity in energy balance regulation
    • Horvath T.L. Synaptic plasticity in energy balance regulation. Obesity (Silver Spring) 14 Suppl 5 (2006) 228S-233S
    • (2006) Obesity (Silver Spring) , vol.14 , Issue.SUPPL. 5
    • Horvath, T.L.1
  • 23
    • 0030990363 scopus 로고    scopus 로고
    • Heterogeneity in the neuropeptide Y-containing neurons of the rat arcuate nucleus: GABAergic and non-GABAergic subpopulations
    • Horvath T.L., Bechmann I., Naftolin F., Kalra S.P., and Leranth C. Heterogeneity in the neuropeptide Y-containing neurons of the rat arcuate nucleus: GABAergic and non-GABAergic subpopulations. Brain Res. 756 (1997) 283-286
    • (1997) Brain Res. , vol.756 , pp. 283-286
    • Horvath, T.L.1    Bechmann, I.2    Naftolin, F.3    Kalra, S.P.4    Leranth, C.5
  • 24
    • 0000739329 scopus 로고
    • alpha-Melanocyte stimulating hormone: immunohistochemical identification and mapping in neurons of rat brain
    • Jacobowitz D.M., and O'Donohue T.L. alpha-Melanocyte stimulating hormone: immunohistochemical identification and mapping in neurons of rat brain. Proc. Natl. Acad. Sci. USA 75 (1978) 6300-6304
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 6300-6304
    • Jacobowitz, D.M.1    O'Donohue, T.L.2
  • 25
    • 0033038418 scopus 로고    scopus 로고
    • Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
    • Kalra S.P., Dube M.G., Pu S., Xu B., Horvath T.L., and Kalra P.S. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr. Rev. 20 (1999) 68-100
    • (1999) Endocr. Rev. , vol.20 , pp. 68-100
    • Kalra, S.P.1    Dube, M.G.2    Pu, S.3    Xu, B.4    Horvath, T.L.5    Kalra, P.S.6
  • 27
    • 0029552617 scopus 로고
    • Differential modulation of brain immediate early genes by intraperitoneal LiCl
    • Lamprecht R., and Dudai Y. Differential modulation of brain immediate early genes by intraperitoneal LiCl. Neuroreport 7 (1995) 289-293
    • (1995) Neuroreport , vol.7 , pp. 289-293
    • Lamprecht, R.1    Dudai, Y.2
  • 29
    • 27344431720 scopus 로고    scopus 로고
    • NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates
    • Luquet S., Perez F.A., Hnasko T.S., and Palmiter R.D. NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates. Science 310 (2005) 683-685
    • (2005) Science , vol.310 , pp. 683-685
    • Luquet, S.1    Perez, F.A.2    Hnasko, T.S.3    Palmiter, R.D.4
  • 30
    • 33846597193 scopus 로고    scopus 로고
    • NPY/AgRP neurons are not essential for feeding responses to glucoprivation
    • Luquet S., Phillips C.T., and Palmiter R.D. NPY/AgRP neurons are not essential for feeding responses to glucoprivation. Peptides 28 (2007) 214-225
    • (2007) Peptides , vol.28 , pp. 214-225
    • Luquet, S.1    Phillips, C.T.2    Palmiter, R.D.3
  • 31
    • 34548493015 scopus 로고    scopus 로고
    • Neurotransmitters in key neurons of the hypothalamus that regulate feeding behavior and body weight
    • Meister B. Neurotransmitters in key neurons of the hypothalamus that regulate feeding behavior and body weight. Physiol. Behav. 92 (2007) 263-271
    • (2007) Physiol. Behav. , vol.92 , pp. 263-271
    • Meister, B.1
  • 33
    • 15544364590 scopus 로고    scopus 로고
    • Maturation of the hypothalamic arcuate agouti-related protein system during postnatal development in the mouse
    • Nilsson I., Johansen J.E., Schalling M., Hokfelt T., and Fetissov S.O. Maturation of the hypothalamic arcuate agouti-related protein system during postnatal development in the mouse. Brain Res. Dev. Brain Res. 155 (2005) 147-154
    • (2005) Brain Res. Dev. Brain Res. , vol.155 , pp. 147-154
    • Nilsson, I.1    Johansen, J.E.2    Schalling, M.3    Hokfelt, T.4    Fetissov, S.O.5
  • 35
    • 0027769916 scopus 로고
    • Discontinuation reactions to alprazolam in panic disorder
    • Pecknold J.C. Discontinuation reactions to alprazolam in panic disorder. J. Psychiatr. Res. 27 Suppl 1 (1993) 155-170
    • (1993) J. Psychiatr. Res. , vol.27 , Issue.SUPPL. 1 , pp. 155-170
    • Pecknold, J.C.1
  • 36
    • 38549159128 scopus 로고    scopus 로고
    • Role of agouti-related protein-expressing neurons in lactation
    • Phillips C.T., and Palmiter R.D. Role of agouti-related protein-expressing neurons in lactation. Endocrinology 149 (2008) 544-550
    • (2008) Endocrinology , vol.149 , pp. 544-550
    • Phillips, C.T.1    Palmiter, R.D.2
  • 37
    • 0036288345 scopus 로고    scopus 로고
    • Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice
    • Qian S., Chen H., Weingarth D., Trumbauer M.E., Novi D.E., Guan X., Yu H., Shen Z., Feng Y., Frazier E., et al. Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice. Mol. Cell. Biol. 22 (2002) 5027-5035
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5027-5035
    • Qian, S.1    Chen, H.2    Weingarth, D.3    Trumbauer, M.E.4    Novi, D.E.5    Guan, X.6    Yu, H.7    Shen, Z.8    Feng, Y.9    Frazier, E.10
  • 38
    • 0034237735 scopus 로고    scopus 로고
    • Lateral parabrachial nucleus lesions in the rat: aversive and appetitive gustatory conditioning
    • Reilly S., and Trifunovic R. Lateral parabrachial nucleus lesions in the rat: aversive and appetitive gustatory conditioning. Brain Res. Bull. 52 (2000) 269-278
    • (2000) Brain Res. Bull. , vol.52 , pp. 269-278
    • Reilly, S.1    Trifunovic, R.2
  • 39
    • 35148838131 scopus 로고    scopus 로고
    • Experimental dissociation of neural circuits underlying conditioned avoidance and hypophagic responses to lithium chloride
    • Rinaman L., and Dzmura V. Experimental dissociation of neural circuits underlying conditioned avoidance and hypophagic responses to lithium chloride. Am. J. Physiol. Regul. Integr. Comp. Physiol. 293 (2007) R1495-R1503
    • (2007) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.293
    • Rinaman, L.1    Dzmura, V.2
  • 40
    • 0037057802 scopus 로고    scopus 로고
    • The need to feed: homeostatic and hedonic control of eating
    • Saper C.B., Chou T.C., and Elmquist J.K. The need to feed: homeostatic and hedonic control of eating. Neuron 36 (2002) 199-211
    • (2002) Neuron , vol.36 , pp. 199-211
    • Saper, C.B.1    Chou, T.C.2    Elmquist, J.K.3
  • 41
    • 54949141091 scopus 로고    scopus 로고
    • alpha(1)-Adrenoceptors in the lateral septal area modulate food intake behaviour in rats
    • Scopinho A.A., Resstel L.B., and Correa F.M. alpha(1)-Adrenoceptors in the lateral septal area modulate food intake behaviour in rats. Br. J. Pharmacol. 155 (2008) 752-756
    • (2008) Br. J. Pharmacol. , vol.155 , pp. 752-756
    • Scopinho, A.A.1    Resstel, L.B.2    Correa, F.M.3
  • 42
    • 0030893647 scopus 로고    scopus 로고
    • Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice
    • Shutter J.R., Graham M., Kinsey A.C., Scully S., Luthy R., and Stark K.L. Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice. Genes Dev. 11 (1997) 593-602
    • (1997) Genes Dev. , vol.11 , pp. 593-602
    • Shutter, J.R.1    Graham, M.2    Kinsey, A.C.3    Scully, S.4    Luthy, R.5    Stark, K.L.6
  • 43
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21 (1999) 70-71
    • (1999) Nat. Genet. , vol.21 , pp. 70-71
    • Soriano, P.1
  • 44
    • 0027976633 scopus 로고
    • c-Fos induction in response to a conditioned stimulus after single trial taste aversion learning
    • Swank M.W., and Bernstein I.L. c-Fos induction in response to a conditioned stimulus after single trial taste aversion learning. Brain Res. 636 (1994) 202-208
    • (1994) Brain Res. , vol.636 , pp. 202-208
    • Swank, M.W.1    Bernstein, I.L.2
  • 45
    • 50249120768 scopus 로고    scopus 로고
    • Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance
    • Tong Q., Ye C.P., Jones J.E., Elmquist J.K., and Lowell B.B. Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance. Nat. Neurosci 11 (2008) 998-1000
    • (2008) Nat. Neurosci , vol.11 , pp. 998-1000
    • Tong, Q.1    Ye, C.P.2    Jones, J.E.3    Elmquist, J.K.4    Lowell, B.B.5
  • 46
    • 0036301721 scopus 로고    scopus 로고
    • Medial versus lateral parabrachial nucleus lesions in the rat: effects on mercaptoacetate-induced feeding and conditioned taste aversion
    • Trifunovic R., and Reilly S. Medial versus lateral parabrachial nucleus lesions in the rat: effects on mercaptoacetate-induced feeding and conditioned taste aversion. Brain Res. Bull. 58 (2002) 107-113
    • (2002) Brain Res. Bull. , vol.58 , pp. 107-113
    • Trifunovic, R.1    Reilly, S.2
  • 47
    • 0018175494 scopus 로고
    • Evidence for two separate opiate peptide neuronal systems
    • Watson S.J., Akil H., Richard III C.W., and Barchas J.D. Evidence for two separate opiate peptide neuronal systems. Nature 275 (1978) 226-228
    • (1978) Nature , vol.275 , pp. 226-228
    • Watson, S.J.1    Akil, H.2    Richard III, C.W.3    Barchas, J.D.4
  • 49
    • 40649093320 scopus 로고    scopus 로고
    • Starvation after AgRP neuron ablation is independent of melanocortin signaling
    • Wu Q., Howell M.P., Cowley M.A., and Palmiter R.D. Starvation after AgRP neuron ablation is independent of melanocortin signaling. Proc. Natl. Acad. Sci. USA 105 (2008) 2687-2692
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 2687-2692
    • Wu, Q.1    Howell, M.P.2    Cowley, M.A.3    Palmiter, R.D.4
  • 50
    • 55249090498 scopus 로고    scopus 로고
    • Ablation of neurons expressing agouti-related protein activates fos and gliosis in postsynaptic target regions
    • Wu Q., Howell M.P., and Palmiter R.D. Ablation of neurons expressing agouti-related protein activates fos and gliosis in postsynaptic target regions. J. Neurosci. 28 (2008) 9218-9226
    • (2008) J. Neurosci. , vol.28 , pp. 9218-9226
    • Wu, Q.1    Howell, M.P.2    Palmiter, R.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.