-
1
-
-
77649209853
-
Gene-environment interactions in obesity
-
Hetherington MM, Cecil JE. Gene-environment interactions in obesity. Forum Nutr 2010;63: 195-203
-
(2010)
Forum Nutr
, vol.63
, pp. 195-203
-
-
Hetherington, M.M.1
Cecil, J.E.2
-
3
-
-
0942279569
-
Energy homeostasis, obesity and eating disorders: Recent advances in endocrinology
-
Gale SM, Castracane VD, Mantzoros CS. Energy homeostasis, obesity and eating disorders: Recent advances in endocrinology. J Nutr 2004;134: 295-8
-
(2004)
J Nutr
, vol.134
, pp. 295-298
-
-
Gale, S.M.1
Castracane, V.D.2
Mantzoros, C.S.3
-
4
-
-
70349207410
-
Annual medical spending attributable to obesity: Payer-And servicespecific estimates
-
Finkelstein EA, Trogdon JG, Cohen JW, et al. Annual medical spending attributable to obesity: Payer-And servicespecific estimates. Health Aff 2009;28: W822-31
-
(2009)
Health Aff
, vol.28
-
-
Finkelstein, E.A.1
Trogdon, J.G.2
Cohen, J.W.3
-
5
-
-
12944260424
-
Surgical management of morbid obesity
-
Schneider BE, Mun EC. Surgical management of morbid obesity. Diabetes Care 2005;28: 475-80
-
(2005)
Diabetes Care
, vol.28
, pp. 475-480
-
-
Schneider, B.E.1
Mun, E.C.2
-
6
-
-
65349194409
-
Results of Roux-en-Y gastric bypass in morbidly obese vs superobese patients: Similar body weight loss, correction of comorbidities, and improvement of quality of life
-
discussion 18
-
Suter M, Calmes JM, Paroz A, et al. Results of Roux-en-Y gastric bypass in morbidly obese vs superobese patients: Similar body weight loss, correction of comorbidities, and improvement of quality of life. Arch Surg 2009;144: 312-18.discussion 18
-
(2009)
Arch Surg
, vol.144
, pp. 312-318
-
-
Suter, M.1
Calmes, J.M.2
Paroz, A.3
-
7
-
-
84872109705
-
A review of late-stage CNS drug candidates for the treatment of obesity
-
Heal DJ, Gosden J, Smith SL. A review of late-stage CNS drug candidates for the treatment of obesity. Int J Obes 2013;37: 107-17
-
(2013)
Int J Obes
, vol.37
, pp. 107-117
-
-
Heal, D.J.1
Gosden, J.2
Smith, S.L.3
-
8
-
-
77952584236
-
Central and peripheral molecular targets for antiobesity pharmacotherapy
-
Valentino MA, Lin JE, Waldman SA. Central and peripheral molecular targets for antiobesity pharmacotherapy. Clin Pharmacol Ther 2010;87: 652-62
-
(2010)
Clin Pharmacol Ther
, vol.87
, pp. 652-662
-
-
Valentino, M.A.1
Lin, J.E.2
Waldman, S.A.3
-
9
-
-
33645468559
-
Safety of drug therapies used for weight loss and treatment of obesity
-
Ioannides-Demos LL, Proietto J, Tonkin AM, et al. Safety of drug therapies used for weight loss and treatment of obesity. Drug Saf 2006;29: 277-302
-
(2006)
Drug Saf
, vol.29
, pp. 277-302
-
-
Ioannides-Demos, L.L.1
Proietto, J.2
Tonkin, A.M.3
-
10
-
-
84891919414
-
Long-Term drug treatment for obesity: A systematic and clinical review
-
Yanovski SZ, Yanovski JA. Long-Term drug treatment for obesity: A systematic and clinical review. J Am Med Assoc 2014;311: 74-86
-
(2014)
J Am Med Assoc
, vol.311
, pp. 74-86
-
-
Yanovski, S.Z.1
Yanovski, J.A.2
-
12
-
-
84898490591
-
The new weight-loss drugs, lorcaserin and phentermine-Topiramate: Slim pickings
-
Woloshin S, Schwartz LM. The new weight-loss drugs, lorcaserin and phentermine-Topiramate: Slim pickingš JAMA Intern Med 2014;174: 615-19
-
(2014)
JAMA Intern Med
, vol.174
, pp. 615-619
-
-
Woloshin, S.1
Schwartz, L.M.2
-
13
-
-
84887155139
-
Evaluation of phentermine and topiramate versus phentermine/ topiramate extended-release in obese adults
-
Aronne LJ, Wadden TA, Peterson C, et al. Evaluation of phentermine and topiramate versus phentermine/ topiramate extended-release in obese adults. Obesity (Silver Spring) 2013;21: 2163-71
-
(2013)
Obesity (Silver Spring
, vol.21
, pp. 2163-2171
-
-
Aronne, L.J.1
Wadden, T.A.2
Peterson, C.3
-
14
-
-
84876031270
-
Clinical utility of phentermine/topiramate (Qsymia) combination for the treatment of obesity
-
Shin JH, Gadde KM. Clinical utility of phentermine/topiramate (Qsymia) combination for the treatment of obesity. Diabetes Metab Syndr Obes 2013;6: 131-9
-
(2013)
Diabetes Metab Syndr Obes
, vol.6
, pp. 131-139
-
-
Shin, J.H.1
Gadde, K.M.2
-
15
-
-
70350619609
-
Effects of liraglutide in the treatment of obesity: A randomised, double-blind, placebo-controlled study
-
Astrup A, Rossner S, Van Gaal L, et al. Effects of liraglutide in the treatment of obesity: A randomised, double-blind, placebo-controlled study. Lancet 2009;374: 1606-16
-
(2009)
Lancet
, vol.374
, pp. 1606-1616
-
-
Astrup, A.1
Rossner, S.2
Van Gaal, L.3
-
16
-
-
84879324574
-
A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II
-
Apovian CM, Aronne L, Rubino D, et al. A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II). Obesity (Silver Spring) 2013;21: 935-43
-
(2013)
Obesity (Silver Spring
, vol.21
, pp. 935-943
-
-
Apovian, C.M.1
Aronne, L.2
Rubino, D.3
-
17
-
-
73949084345
-
Weight loss, HbA1c reduction, and tolerability of cetilistat in a randomized, placebo-controlled phase 2 trial in obese diabetics: Comparison with orlistat (Xenical
-
Kopelman P, Groot Gde H, Rissanen A, et al. Weight loss, HbA1c reduction, and tolerability of cetilistat in a randomized, placebo-controlled phase 2 trial in obese diabetics: Comparison with orlistat (Xenical). Obesity (Silver Spring) 2010;18: 108-15
-
(2010)
Obesity (Silver Spring
, vol.18
, pp. 108-115
-
-
Kopelman, P.1
Groot Gde, H.2
Rissanen, A.3
-
19
-
-
79961165599
-
Current and future drug targets in weight management
-
Witkamp RF. Current and future drug targets in weight management. Pharm Res 2011;28: 1792-818
-
(2011)
Pharm Res
, vol.28
, pp. 1792-1818
-
-
Witkamp, R.F.1
-
20
-
-
34248342673
-
Effect of NPY5R antagonist MK-0557 on weight regain after very-low-calorie diet-induced weight loss
-
Erondu N, Wadden T, Gantz I, et al. Effect of NPY5R antagonist MK-0557 on weight regain after very-low-calorie diet-induced weight loss. Obesity (Silver Spring) 2007;15: 895-905
-
(2007)
Obesity (Silver Spring
, vol.15
, pp. 895-905
-
-
Erondu, N.1
Wadden, T.2
Gantz, I.3
-
21
-
-
80053193844
-
Neuropsychiatric adverse effects of centrally acting antiobesity drugs
-
Nathan PJ, O'Neill BV, Napolitano A, et al. Neuropsychiatric adverse effects of centrally acting antiobesity drugs. CNS Neurosci Ther 2011;17: 490-505
-
(2011)
CNS Neurosci Ther
, vol.17
, pp. 490-505
-
-
Nathan, P.J.1
O'Neill, B.V.2
Napolitano, A.3
-
22
-
-
84866108680
-
Limitations in anti-obesity drug development: The critical role of hunger-promoting neurons
-
Dietrich MO, Horvath TL. Limitations in anti-obesity drug development: The critical role of hunger-promoting neurons. Nat Rev Drug Discov 2012;11: 675-91
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 675-691
-
-
Dietrich, M.O.1
Horvath, T.L.2
-
23
-
-
31944452253
-
The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight
-
King BM. The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight. Physiol Behav 2006;87: 221-44
-
(2006)
Physiol Behav
, vol.87
, pp. 221-244
-
-
King, B.M.1
-
24
-
-
0035757969
-
Adrenoceptors, uncoupling proteins, and energy expenditure
-
Collins S, Cao W, Daniel KW, et al. Adrenoceptors, uncoupling proteins, and energy expenditure. Exp Biol Med 2001;226: 982-90
-
(2001)
Exp Biol Med
, vol.226
, pp. 982-990
-
-
Collins, S.1
Cao, W.2
Daniel, K.W.3
-
25
-
-
33745872950
-
CB1 cannabinoid receptor antagonists for treatment of obesity and prevention of comorbid metabolic disorders
-
Antel J, Gregory PC, Nordheim U. CB1 cannabinoid receptor antagonists for treatment of obesity and prevention of comorbid metabolic disorders. J Med Chem 2006;49: 4008-16
-
(2006)
J Med Chem
, vol.49
, pp. 4008-4016
-
-
Antel, J.1
Gregory, P.C.2
Nordheim, U.3
-
26
-
-
33646889517
-
Cannabinoids, opioids and eating behavior: The molecular face of hedonism
-
Cota D, Tschop MH, Horvath TL, et al. Cannabinoids, opioids and eating behavior: The molecular face of hedonism? Brain Res Rev 2006;51: 85-107
-
(2006)
Brain Res Rev
, vol.51
, pp. 85-107
-
-
Cota, D.1
Tschop, M.H.2
Horvath, T.L.3
-
27
-
-
78650752631
-
Reward, dopamine and the control of food intake: Implications for obesity
-
Volkow ND, Wang G-J, Baler RD. Reward, dopamine and the control of food intake: Implications for obesity. Trends Cogn Sci 2011;15: 37-46
-
(2011)
Trends Cogn Sci
, vol.15
, pp. 37-46
-
-
Volkow, N.D.1
Wang, G.-J.2
Baler, R.D.3
-
28
-
-
62649127050
-
Stimulation of cholecystokinin-A receptors With Gl181771X: A failed clinical trial that did not test the pharmacogenetic hypothesis for reduction of food intake
-
Roses AD. Stimulation of cholecystokinin-A receptors With Gl181771X: A failed clinical trial that did not test the pharmacogenetic hypothesis for reduction of food intake. Clin Pharmacol Ther 2009;85: 362-5
-
(2009)
Clin Pharmacol Ther
, vol.85
, pp. 362-365
-
-
Roses, A.D.1
-
29
-
-
51549104158
-
Y2 receptor gene variants reduce the risk of hypertension in obese children and adolescents
-
Santoro N, del Giudice EM, Grandone A, et al. Y2 receptor gene variants reduce the risk of hypertension in obese children and adolescents. J Hypertens 2008;26: 1590-4
-
(2008)
J Hypertens
, vol.26
, pp. 1590-1594
-
-
Santoro, N.1
Del Giudice, E.M.2
Grandone, A.3
-
30
-
-
0032747280
-
Recombinant leptin for weight loss in obese and lean adults, A randomized, controlled, dose-escalation trial
-
Heymsfield SB, Greenberg AS, Fujioka K, et al. Recombinant leptin for weight loss in obese and lean adults, A randomized, controlled, dose-escalation trial. JAMA 1999;282: 1568-75
-
(1999)
JAMA
, vol.282
, pp. 1568-1575
-
-
Heymsfield, S.B.1
Greenberg, A.S.2
Fujioka, K.3
-
31
-
-
69749086148
-
Enhanced weight loss with pramlintide/ metreleptin: An integrated neurohormonal approach to obesity pharmacotherapy
-
Ravussin E, Smith SR, Mitchell JA, et al. Enhanced weight loss with pramlintide/ metreleptin: An integrated neurohormonal approach to obesity pharmacotherapy. Obesity (Silver Spring) 2009;17: 1736-43
-
(2009)
Obesity (Silver Spring
, vol.17
, pp. 1736-1743
-
-
Ravussin, E.1
Smith, S.R.2
Mitchell, J.A.3
-
32
-
-
80555135931
-
Novel strategy for the use of leptin for obesity therapy
-
Tam CS, Lecoultre V, Ravussin E. Novel strategy for the use of leptin for obesity therapy. Expert Opin Biol Ther 2011;11: 1677-85
-
(2011)
Expert Opin Biol Ther
, vol.11
, pp. 1677-1685
-
-
Tam, C.S.1
Lecoultre, V.2
Ravussin, E.3
-
33
-
-
0029896530
-
Role of leptin in the neuroendocrine response to fasting
-
Ahima RS, Prabakaran D, Mantzoros C, et al. Role of leptin in the neuroendocrine response to fasting. Nature 1996;382: 250-2
-
(1996)
Nature
, vol.382
, pp. 250-252
-
-
Ahima, R.S.1
Prabakaran, D.2
Mantzoros, C.3
-
34
-
-
0036093071
-
Low dose leptin administration reverses effects of sustained weight-reduction on energy expenditure and circulating concentrations of thyroid hormones
-
Rosenbaum M, Murphy EM, Heymsfield SB, et al. Low dose leptin administration reverses effects of sustained weight-reduction on energy expenditure and circulating concentrations of thyroid hormones. J Clin Endocrinol Metab 2002;87: 2391-4
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 2391-2394
-
-
Rosenbaum, M.1
Murphy, E.M.2
Heymsfield, S.B.3
-
35
-
-
19444379385
-
General pharmacology of CKD-732, a new anticancer agent: Effects on central nervous, cardiovascular, and respiratory system
-
Kim EJ, Shin WH. General pharmacology of CKD-732, a new anticancer agent: Effects on central nervous, cardiovascular, and respiratory system. Biol Pharm Bull 2005;28: 217-23
-
(2005)
Biol Pharm Bull
, vol.28
, pp. 217-223
-
-
Kim, E.J.1
Shin, W.H.2
-
36
-
-
34248143523
-
Assessment of the anti-obesity effects of the TNP-470 analog CKD-732
-
Kim YM, An JJ, Jin Y-J, et al. Assessment of the anti-obesity effects of the TNP-470 analog, CKD-732. J Mol Endocrinol 2007;38: 455-65
-
(2007)
J Mol Endocrinol
, vol.38
, pp. 455-465
-
-
Kim, Y.M.1
An, J.J.2
Jin, Y.-J.3
-
38
-
-
13244265583
-
Novel inhibitors targeted to methionine aminopeptidase 2 (MetAP2) strongly inhibit the growth of cancers in xenografted nude model
-
Chun E, Han CK, Yoon JH, et al. Novel inhibitors targeted to methionine aminopeptidase 2 (MetAP2) strongly inhibit the growth of cancers in xenografted nude model. Int J Cancer 2005;114: 124-30
-
(2005)
Int J Cancer
, vol.114
, pp. 124-130
-
-
Chun, E.1
Han, C.K.2
Yoon, J.H.3
-
40
-
-
84884905713
-
Ascending dose-controlled trial of beloranib, a novel obesity treatment for safety, tolerability, and weight loss in obese women
-
Hughes TE, Kim DD, Marjason J, et al. Ascending dose-controlled trial of beloranib, a novel obesity treatment for safety, tolerability, and weight loss in obese women. Obesity (Silver Spring) 2013;21: 1782-8
-
(2013)
Obesity (Silver Spring
, vol.21
, pp. 1782-1788
-
-
Hughes, T.E.1
Kim, D.D.2
Marjason, J.3
-
41
-
-
79551555006
-
Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis
-
Rossi J, Balthasar N, Olson D, et al. Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis. Cell Metab 2011;13: 195-204
-
(2011)
Cell Metab
, vol.13
, pp. 195-204
-
-
Rossi, J.1
Balthasar, N.2
Olson, D.3
-
42
-
-
58249087146
-
Modulation of blood pressure by central melanocortinergic pathways
-
Greenfield JR, Miller JW, Keogh JM, et al. Modulation of blood pressure by central melanocortinergic pathways. N Engl J Med 2009;360: 44-52
-
(2009)
N Engl J Med
, vol.360
, pp. 44-52
-
-
Greenfield, J.R.1
Miller, J.W.2
Keogh, J.M.3
-
43
-
-
70450245171
-
Potent and selective agonism of the melanocortin receptor 4 with MK-0493 does not induce weight loss in obese human subjects: Energy intake predicts lack of weight loss efficacy
-
Krishna R, Gumbiner B, Stevens C, et al. Potent and selective agonism of the melanocortin receptor 4 with MK-0493 does not induce weight loss in obese human subjects: Energy intake predicts lack of weight loss efficacy. Clin Pharmacol Ther 2009;86: 659-66
-
(2009)
Clin Pharmacol Ther
, vol.86
, pp. 659-666
-
-
Krishna, R.1
Gumbiner, B.2
Stevens, C.3
-
45
-
-
84873301711
-
Melanocortin 4 receptors reciprocally regulate sympathetic and parasympathetic preganglionic neurons
-
Sohn J-W, Harris LE, Berglund ED, et al. Melanocortin 4 receptors reciprocally regulate sympathetic and parasympathetic preganglionic neurons. Cell 2013;152: 612-19
-
(2013)
Cell
, vol.152
, pp. 612-619
-
-
Sohn, J.-W.1
Harris, L.E.2
Berglund, E.D.3
-
46
-
-
84873053314
-
Chronic treatment with a melanocortin-4 receptor agonist causes weight loss, reduces insulin resistance, and improves cardiovascular function in diet-induced obese rhesus macaques
-
Kievit P, Halem H, Marks DL, et al. Chronic treatment with a melanocortin-4 receptor agonist causes weight loss, reduces insulin resistance, and improves cardiovascular function in diet-induced obese rhesus macaques. Diabetes 2013;62: 490-7
-
(2013)
Diabetes
, vol.62
, pp. 490-497
-
-
Kievit, P.1
Halem, H.2
Marks, D.L.3
-
47
-
-
84904328162
-
-
National Institutes of Health, Washington, DC Available from
-
Phase 2 study to evaluate safety and efficacy of Rm-493 in obese patients. National Institutes of Health, Washington, DC; 2014. Available from: Http: //clinicaltrials. gov/ct2/show/NCT01749137?term=RM-493&rank=1
-
(2014)
Phase 2 study to evaluate safety and efficacy of Rm-493 in obese patients
-
-
-
48
-
-
84904282384
-
-
National Institutes of Health Washington, DC Available from
-
Effects of RM-493 on energy expenditure in obese individuals. National Institutes of Health, Washington, DC; 2014. Available from: Http: //clinicaltrials. gov/ct2/show/NCT01867437?term=RM-493&rank=2
-
(2014)
Effects of RM-493 on energy expenditure in obese individuals
-
-
-
52
-
-
84904280153
-
-
Societe de Conseils de Recherches et D'Applications Scientifiques S.A.S. Fr.Louisiana State University and Agriculture and Mechanical College; Ipsen Pharma. WO2009061411A2
-
Societe de Conseils de Recherches et D'Applications Scientifiques S.A.S., Fr.; Louisiana State University and Agriculture and Mechanical College; Ipsen Pharma. Use of melanocortin receptor agonist peptide compounds to treat insulin resistance. WO2009061411A2; 2009
-
(2009)
Use of melanocortin receptor agonist peptide compounds to treat insulin resistance
-
-
-
55
-
-
78651111374
-
Histamine H3 receptor as a drug discovery target
-
Berlin M, Boyce CW, de Lera Ruiz M. Histamine H3 receptor as a drug discovery target. J Med Chem 2011;54: 26-53
-
(2011)
J Med Chem
, vol.54
, pp. 26-53
-
-
Berlin, M.1
Boyce, C.W.2
De Lera Ruiz, M.3
-
56
-
-
84885172697
-
Bicyclic and tricyclic heterocycle derivatives as histamine H3 receptor antagonists for the treatment of obesity
-
de Lera Ruiz M, Zheng J, Berlin MY, et al. Bicyclic and tricyclic heterocycle derivatives as histamine H3 receptor antagonists for the treatment of obesity. Bioorg Med Chem Lett 2013;23: 6004-9
-
(2013)
Bioorg Med Chem Lett
, vol.23
, pp. 6004-6009
-
-
De Lera Ruiz, M.1
Zheng, J.2
Berlin, M.Y.3
-
58
-
-
79956202758
-
A small-molecule inhibitor of enterocytic microsomal triglyceride transfer protein, SLx-4090: Biochemical, pharmacodynamic, pharmacokinetic, and safety profile
-
Kim E, Campbell S, Schueller O, et al. A small-molecule inhibitor of enterocytic microsomal triglyceride transfer protein, SLx-4090: Biochemical, pharmacodynamic, pharmacokinetic, and safety profile. J Pharmacol Exp Ther 2011;337: 775-85
-
(2011)
J Pharmacol Exp Ther
, vol.337
, pp. 775-785
-
-
Kim, E.1
Campbell, S.2
Schueller, O.3
-
60
-
-
84904355592
-
-
Kadmon Available from
-
Clinical pipeline. Kadmon, 2014. Available from: Http: //kadmon. com/docs/science-pipeline
-
(2014)
Clinical pipeline
-
-
-
61
-
-
84880133265
-
Microsomal transfer protein inhibition in humans
-
Cuchel M, Rader DJ. Microsomal transfer protein inhibition in humans. Curr Opin Lipidol 2013;24: 246-50
-
(2013)
Curr Opin Lipidol
, vol.24
, pp. 246-250
-
-
Cuchel, M.1
Rader, D.J.2
-
62
-
-
34249802297
-
Biologic activity of dirlotapide, a novel microsomal triglyceride transfer protein inhibitor, for weight loss in obese dogs
-
Wren JA, King VL, Campbell SL, et al. Biologic activity of dirlotapide, a novel microsomal triglyceride transfer protein inhibitor, for weight loss in obese dogs. J Vet Pharmacol Ther 2007;30: 33-42
-
(2007)
J Vet Pharmacol Ther
, vol.30
, pp. 33-42
-
-
Wren, J.A.1
King, V.L.2
Campbell, S.L.3
-
63
-
-
79956333142
-
JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, ameliorates impaired glucose and lipid metabolism in Zucker diabetic fatty rats
-
Hata T, Mera Y, Kawai T, et al. JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, ameliorates impaired glucose and lipid metabolism in Zucker diabetic fatty rats. Diabetes Obes Metab 2011;13: 629-38
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 629-638
-
-
Hata, T.1
Mera, Y.2
Kawai, T.3
-
64
-
-
52649083832
-
Remogliflozin etabonate, in a novel category of selective low-Affinity sodium glucose cotransporter (SGLT2) inhibitors, exhibits antidiabetic efficacy in rodent models
-
Fujimori Y, Katsuno K, Nakashima I, et al. Remogliflozin etabonate, in a novel category of selective low-Affinity sodium glucose cotransporter (SGLT2) inhibitors, exhibits antidiabetic efficacy in rodent models. J Pharmacol Exp Ther 2008;327: 268-76
-
(2008)
J Pharmacol Exp Ther
, vol.327
, pp. 268-276
-
-
Fujimori, Y.1
Katsuno, K.2
Nakashima, I.3
-
65
-
-
84880643826
-
First human doseescalation study with remogliflozin etabonate, a selective inhibitor of the sodium-glucose transporter 2 (SGLT2), in healthy subjects and in subjects with type 2 diabetes mellitus
-
Kapur A, O'Connor-Semmes R, Hussey EK, et al. First human doseescalation study with remogliflozin etabonate, a selective inhibitor of the sodium-glucose transporter 2 (SGLT2), in healthy subjects and in subjects with type 2 diabetes mellitus. BMC Pharmacol Toxicol 2013;14: 26
-
(2013)
BMC Pharmacol Toxicol
, vol.14
, pp. 26
-
-
Kapur, A.1
O'Connor-Semmes, R.2
Hussey, E.K.3
-
66
-
-
84904295149
-
-
BHV Pharma-Our pipeline. Available from
-
BHV Pharma-Our pipeline. BHV Pharma, 2014. Available from: Http: //www.bhvpharma.com/pipeline/
-
(2014)
BHV Pharma
-
-
-
67
-
-
84897447957
-
Canagliflozin: Effects in overweight and obese subjects without diabetes mellitus
-
Bays HE, Weinstein R, Law G, et al. Canagliflozin: Effects in overweight and obese subjects without diabetes mellitus. Obesity (Silver Spring) 2014;22: 1042-9
-
(2014)
Obesity (Silver Spring
, vol.22
, pp. 1042-1049
-
-
Bays, H.E.1
Weinstein, R.2
Law, G.3
-
68
-
-
84893844270
-
Paradoxical insights into whole body metabolic adaptations following SGLT2 inhibition
-
Cefalu WT. Paradoxical insights into whole body metabolic adaptations following SGLT2 inhibition. J Clin Invest 2014;124: 485-7
-
(2014)
J Clin Invest
, vol.124
, pp. 485-487
-
-
Cefalu, W.T.1
-
70
-
-
79958282647
-
Naltrexone SR/ bupropion SR (Contrave): A new approach to weight loss in obese adults
-
Ornellas T, Chavez B. Naltrexone SR/ bupropion SR (Contrave): A new approach to weight loss in obese adults. P T 2011;36: 255-62
-
(2011)
P T
, vol.36
, pp. 255-262
-
-
Ornellas, T.1
Chavez, B.2
-
71
-
-
84904309715
-
-
Available from
-
Empatic. Orexigen; 2014. Available from: Http: //www. orexigen.com/product-candidates/ empatic.html
-
(2014)
Empatic Orexigen
-
-
-
72
-
-
84904361526
-
-
National Institutes of Health, Washington DC Available from
-
Exenatide in extreme pediatric obesity. National Institutes of Health, Washington, DC; 2014. Available from: Http: //clinicaltrials. gov/ct2/show/NCT01237197? term=exenatide+and+Minnesota&rank=2
-
(2014)
Exenatide in extreme pediatric obesity
-
-
-
73
-
-
84904298529
-
-
National Institutes of Health, Washington DC Available from
-
Topiramate in adolescents with severe obesity. National Institutes of Health, Washington, DC; 2014. Available from: Http: //clinicaltrials. gov/ct2/show/NCT01859013? term=topiramate+and+minnesota&rank=1
-
(2014)
Topiramate in adolescents with severe obesity
-
-
-
75
-
-
0842348094
-
-
American Diabetes Association American Psychiatric Association American Association of Clinical Endocrinologists. et al. Consensus development conference on antipsychotic drugs and obesity and diabetes
-
American Diabetes Association; American Psychiatric Association; American Association of Clinical Endocrinologists. et al. Consensus development conference on antipsychotic drugs and obesity and diabetes. Diabetes Care 2004;27: 596-601
-
(2004)
Diabetes Care
, vol.27
, pp. 596-601
-
-
-
77
-
-
84904331399
-
-
National Institutes of Health, Washington DC Available from
-
Amlexanox for type 2 diabetes and obesity. National Institutes of Health, Washington, DC; 2014. Available from: Http: //clinicaltrials. gov/ct2/show/NCT01842282? term=amlexanox&rank=2
-
(2014)
Amlexanox for type 2 diabetes and obesity
-
-
-
78
-
-
84875179301
-
An inhibitor of the protein kinases TBK1 and IKK-varepsilon improves obesity-related metabolic dysfunctions in mice
-
Reilly SM, Chiang SH, Decker SJ, et al. An inhibitor of the protein kinases TBK1 and IKK-varepsilon improves obesity-related metabolic dysfunctions in mice. Nat Med 2013;19: 313-21.
-
(2013)
Nat Med
, vol.19
, pp. 313-321
-
-
Reilly, S.M.1
Chiang, S.H.2
Decker, S.J.3
|