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Volumn 121, Issue 6, 2011, Pages 2413-2421

Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; LEPTIN RECEPTOR; PAIRED LIKE HOMEOBOX 2B; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 79957896911     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI43703     Document Type: Article
Times cited : (140)

References (41)
  • 1
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • DOI 10.1038/372425a0
    • Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature. 1994;372(6505):425-432. (Pubitemid 24365442)
    • (1994) Nature , vol.372 , Issue.6505 , pp. 425-432
    • Zhang, Y.1    Proenca, R.2    Maffei, M.3    Barone, M.4    Leopold, L.5    Friedman, J.M.6
  • 2
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • DOI 10.1038/27376
    • Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature. 1998;395(6704):763-770. (Pubitemid 28485436)
    • (1998) Nature , vol.395 , Issue.6704 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 3
    • 0029073613 scopus 로고
    • Weight-reducing effects of the plasma protein encoded by the obese gene
    • Halaas JL, et al. Weight-reducing effects of the plasma protein encoded by the obese gene. Science. 1995;269(5223):543-546.
    • (1995) Science , vol.269 , Issue.5223 , pp. 543-546
    • Halaas, J.L.1
  • 9
    • 77951878302 scopus 로고    scopus 로고
    • A beta(3)-adrenergic-leptin-melanocortin circuit regulates behavioral and metabolic changes induced by chronic stress
    • Chuang JC, et al. A beta(3)-adrenergic-leptin-melanocortin circuit regulates behavioral and metabolic changes induced by chronic stress. Biol Psychiatry. 2010;67(11):1075-1182.
    • (2010) Biol Psychiatry , vol.67 , Issue.11 , pp. 1075-1182
    • Chuang, J.C.1
  • 10
    • 42449086900 scopus 로고    scopus 로고
    • Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome
    • DOI 10.1210/en.2007-1200
    • Bingham NC, Anderson KK, Reuter AL, Stallings NR, Parker KL. Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome. Endocrinology. 2008;149(5):2138-2148. (Pubitemid 351574486)
    • (2008) Endocrinology , vol.149 , Issue.5 , pp. 2138-2148
    • Bingham, N.C.1    Anderson, K.K.2    Reuter, A.L.3    Stallings, N.R.4    Parker, K.L.5
  • 12
    • 0031054014 scopus 로고    scopus 로고
    • Leptin activates neurons in ventrobasal hypothalamus and brainstem
    • DOI 10.1210/en.138.2.839
    • Elmquist JK, Ahima RS, Maratos-Flier E, Flier JS, Saper CB. Leptin activates neurons in ventrobasal hypothalamus and brainstem. Endocrinology. 1997;138(2):839-842. (Pubitemid 27110941)
    • (1997) Endocrinology , vol.138 , Issue.2 , pp. 839-842
    • Elmquist, J.K.1    Ahima, R.S.2    Maratos-Flier, E.3    Flier, J.S.4    Saper, C.B.5
  • 13
    • 66149141484 scopus 로고    scopus 로고
    • Leptin targets in the mouse brain
    • Scott MM, et al. Leptin targets in the mouse brain. J Comp Neurol. 2009;514(5):518-532.
    • (2009) J Comp Neurol , vol.514 , Issue.5 , pp. 518-532
    • Scott, M.M.1
  • 14
    • 0032566796 scopus 로고    scopus 로고
    • Association of leptin receptor (OB-Rb), NPY and GLP-1 gene expression in the ovine and murine brainstem
    • DOI 10.1016/S0167-0115(98)00078-0, PII S0167011598000780
    • Mercer JG, Moar KM, Findlay PA, Hoggard N, Adam CL. Association of leptin receptor (OB-Rb), NPY and GLP-1 gene expression in the ovine and murine brainstem. Regul Pept. 1998;75-76:271-278. (Pubitemid 28477537)
    • (1998) Regulatory Peptides , vol.75-76 , pp. 271-278
    • Mercer, J.G.1    Moar, K.M.2    Findlay, P.A.3    Hoggard, N.4    Adam, C.L.5
  • 15
    • 0036142589 scopus 로고    scopus 로고
    • Evidence that the caudal brainstem is a target for the inhibitory effect of leptin on food intake
    • DOI 10.1210/en.143.1.239
    • Grill HJ, Schwartz MW, Kaplan JM, Foxhall JS, Breininger J, Baskin DG. Evidence that the caudal brainstem is a target for the inhibitory effect of leptin on food intake. Endocrinology. 2002;143(1):239-246. (Pubitemid 34056425)
    • (2002) Endocrinology , vol.143 , Issue.1 , pp. 239-246
    • Grill, H.J.1    Schwartz, M.W.2    Kaplan, J.M.3    Foxhall, J.S.4    Breininger, J.5    Baskin, D.G.6
  • 16
    • 34249785695 scopus 로고    scopus 로고
    • Leptin and the control of food intake: Neurons in the nucleus of the solitary tract are activated by both gastric distension and leptin
    • DOI 10.1210/en.2006-1572
    • Huo L, Maeng L, Bjorbaek C, Grill HJ. Leptin and the control of food intake: neurons in the nucleus of the solitary tract are activated by both gastric distension and leptin. Endocrinology. 2007;148(5):2189-2197. (Pubitemid 46997029)
    • (2007) Endocrinology , vol.148 , Issue.5 , pp. 2189-2197
    • Huo, L.1    Maeng, L.2    Bjorbaek, C.3    Grill, H.J.4
  • 17
    • 0036773262 scopus 로고    scopus 로고
    • Leptin and neuropeptide Y have opposing modulatory effects on nucleus of the solitary tract neurophysiological responses to gastric loads: Implications for the control of food intake
    • DOI 10.1210/en.2002-220352
    • Schwartz GJ, Moran TH. Leptin and neuropeptide y have opposing modulatory effects on nucleus of the solitary tract neurophysiological responses to gastric loads: implications for the control of food intake. Endocrinology. 2002;143(10):3779-3784. (Pubitemid 35244356)
    • (2002) Endocrinology , vol.143 , Issue.10 , pp. 3779-3784
    • Schwartz, G.J.1    Moran, T.H.2
  • 18
    • 0035120192 scopus 로고    scopus 로고
    • Leptin amplifies the feeding inhibition and neural activation arising from a gastric nutrient preload
    • DOI 10.1016/S0031-9384(00)00393-0, PII S0031938400003930
    • Emond M, Ladenheim EE, Schwartz GJ, Moran TH. Leptin amplifies the feeding inhibition and neural activation arising from a gastric nutrient preload. Physiol Behav. 2001;72(1-2):123-128. (Pubitemid 32184801)
    • (2001) Physiology and Behavior , vol.72 , Issue.1-2 , pp. 123-128
    • Emond, M.1    Ladenheim, E.E.2    Schwartz, G.J.3    Moran, T.H.4
  • 19
    • 33745034786 scopus 로고    scopus 로고
    • Rapid inhibition of neural excitability in the nucleus tractus solitarii by leptin: Implications for ingestive behaviour
    • DOI 10.1113/jphysiol.2006.106336
    • Williams KW, Smith BN. Rapid inhibition of neural excitability in the nucleus tractus solitarii by leptin: implications for ingestive behaviour. J Physiol. 2006;573(pt 2):395-412. (Pubitemid 43871055)
    • (2006) Journal of Physiology , vol.573 , Issue.2 , pp. 395-412
    • Williams, K.W.1    Smith, B.N.2
  • 20
    • 33947413088 scopus 로고    scopus 로고
    • Rapid inhibition of neurons in the dorsal motor nucleus of the vagus by leptin
    • DOI 10.1210/en.2006-1098
    • Williams KW, Zsombok A, Smith BN. Rapid inhibition of neurons in the dorsal motor nucleus of the vagus by leptin. Endocrinology. 2007; 148(4):1868-1881. (Pubitemid 46457122)
    • (2007) Endocrinology , vol.148 , Issue.4 , pp. 1868-1881
    • Williams, K.W.1    Zsombok, A.2    Smith, B.N.3
  • 24
    • 0030731439 scopus 로고    scopus 로고
    • Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis
    • Pattyn A, Morin X, Cremer H, Goridis C, Brunet JF. Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis. Development. 1997;124(20):4065-4075. (Pubitemid 27483333)
    • (1997) Development , vol.124 , Issue.20 , pp. 4065-4075
    • Pattyn, A.1    Morin, X.2    Cremer, H.3    Goridis, C.4    Brunet, J.-F.5
  • 25
    • 0033609337 scopus 로고    scopus 로고
    • The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives
    • DOI 10.1038/20700
    • Pattyn A, Morin X, Cremer H, Goridis C, Brunet JF. The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives. Nature. 1999;399(6734):366-370. (Pubitemid 29318135)
    • (1999) Nature , vol.399 , Issue.6734 , pp. 366-370
    • Pattyn, A.1    Morin, X.2    Cremer, H.3    Goridis, C.4    Brunet, J.-F.5
  • 26
    • 0033119681 scopus 로고    scopus 로고
    • Specification of neurotransmitter identity by Phox2 proteins in neural crest stem cells
    • DOI 10.1016/S0896-6273(00)80729-1
    • Lo L, Morin X, Brunet JF, Anderson DJ. Specification of neurotransmitter identity by Phox2 proteins in neural crest stem cells. Neuron. 1999;22(4):693-705. (Pubitemid 29203493)
    • (1999) Neuron , vol.22 , Issue.4 , pp. 693-705
    • Lo, L.1    Morin, X.2    Brunet, J.-F.3    Anderson, D.J.4
  • 27
    • 0034034865 scopus 로고    scopus 로고
    • Specification of the central noradrenergic phenotype by the homeobox gene Phox2b
    • DOI 10.1006/mcne.1999.0826
    • Pattyn A, Goridis C, Brunet JF. Specification of the central noradrenergic phenotype by the homeobox gene Phox2b. Mol Cell Neurosci. 2000;15(3):235-243. (Pubitemid 30193798)
    • (2000) Molecular and Cellular Neurosciences , vol.15 , Issue.3 , pp. 235-243
    • Pattyn, A.1    Goridis, C.2    Brunet, J.-F.3
  • 29
    • 79551555006 scopus 로고    scopus 로고
    • Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis
    • Rossi J, et al. Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis. Cell Metab. 2011;13(2):195-204.
    • (2011) Cell Metab , vol.13 , Issue.2 , pp. 195-204
    • Rossi, J.1
  • 31
    • 38549123536 scopus 로고    scopus 로고
    • Divergent leptin signaling in proglucagon neurons of the nucleus of the solitary tract in mice and rats
    • DOI 10.1210/en.2007-0633
    • Huo L, Gamber KM, Grill HJ, Bjorbaek C. Divergent leptin signaling in proglucagon neurons of the nucleus of the solitary tract in mice and rats. Endocrinology. 2008;149(2):492-497. (Pubitemid 351159324)
    • (2008) Endocrinology , vol.149 , Issue.2 , pp. 492-497
    • Huo, L.1    Gamber, K.M.2    Grill, H.J.3    Bjorbaek, C.4
  • 32
    • 72649103549 scopus 로고    scopus 로고
    • Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation
    • Hayes MR, et al. Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation. Cell Metab. 2010;11(1):77-83.
    • (2010) Cell Metab , vol.11 , Issue.1 , pp. 77-83
    • Hayes, M.R.1
  • 33
    • 64949116079 scopus 로고    scopus 로고
    • The nucleus tractus solitarius: A portal for visceral afferent signal processing, energy status assessment and integration of their combined effects on food intake
    • Grill HJ, Hayes MR. The nucleus tractus solitarius: a portal for visceral afferent signal processing, energy status assessment and integration of their combined effects on food intake. Int J Obes (Lond). 2009;33 suppl 1:S11-S15.
    • (2009) Int J Obes (Lond) , vol.33 , Issue.SUPPL. 1
    • Grill, H.J.1    Hayes, M.R.2
  • 34
    • 63849112609 scopus 로고    scopus 로고
    • Hindbrain leptin stimulation induces anorexia and hyperthermia mediated by hindbrain melanocortin receptors
    • Skibicka KP, Grill HJ. Hindbrain leptin stimulation induces anorexia and hyperthermia mediated by hindbrain melanocortin receptors. Endocrinology. 2009;150(4):1705-1711.
    • (2009) Endocrinology , vol.150 , Issue.4 , pp. 1705-1711
    • Skibicka, K.P.1    Grill, H.J.2
  • 35
    • 72449121795 scopus 로고    scopus 로고
    • Leptin and the systems neuroscience of meal size control
    • Grill HJ. Leptin and the systems neuroscience of meal size control. Front Neuroendocrinol. 2010; 31(1):61-78.
    • (2010) Front Neuroendocrinol , vol.31 , Issue.1 , pp. 61-78
    • Grill, H.J.1
  • 36
    • 34247639607 scopus 로고    scopus 로고
    • Characterization of brainstem preproglucagon projections to the paraventricular and dorsomedial hypothalamic nuclei
    • DOI 10.1016/j.brainres.2007.02.043, PII S0006899307003423
    • Vrang N, Hansen M, Larsen PJ, Tang-Christensen M. Characterization of brainstem preproglucagon projections to the paraventricular and dorsomedial hypothalamic nuclei. Brain Res. 2007;1149:118-126. (Pubitemid 46671416)
    • (2007) Brain Research , vol.1149 , Issue.1 , pp. 118-126
    • Vrang, N.1    Hansen, M.2    Larsen, P.J.3    Tang-Christensen, M.4
  • 38
    • 77449101244 scopus 로고    scopus 로고
    • A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes
    • Butler AA, Kozak LP. A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes. Diabetes. 2010;59(2):323-329.
    • (2010) Diabetes , vol.59 , Issue.2 , pp. 323-329
    • Butler, A.A.1    Kozak, L.P.2
  • 39
    • 0024158627 scopus 로고
    • Effect of gastrointestinal peptides on ingestion in old and young mice
    • DOI 10.1016/0196-9781(88)90254-9
    • Silver AJ, Flood JF, Morley JE. Effect of gastrointestinal peptides on ingestion in old and young mice. Peptides. 1988;9(2):221-225. (Pubitemid 19260225)
    • (1988) Peptides , vol.9 , Issue.2 , pp. 221-225
    • Silver, A.J.1    Flood, J.F.2    Morley, J.E.3
  • 41
    • 77249146406 scopus 로고    scopus 로고
    • Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons
    • Williams KW, et al. Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons. J Neurosci. 2010;30(7):2472-2479.
    • (2010) J Neurosci , vol.30 , Issue.7 , pp. 2472-2479
    • Williams, K.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.