메뉴 건너뛰기




Volumn 848, Issue , 2015, Pages 211-234

Aptamer–siRNA chimeras for HIV

Author keywords

[No Author keywords available]

Indexed keywords

APTAMER; CD4 ANTIBODY; CD4 ANTIGEN; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41; GP 120 ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS 1 PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; PEGAPTANIB; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VIRUS ANTIBODY; PEPTIDE APTAMER; RECOMBINANT DNA;

EID: 84924864415     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-1-4939-2432-5_11     Document Type: Article
Times cited : (24)

References (154)
  • 1
    • 0019782357 scopus 로고
    • Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: Evidence of a new acquired cellular immunodeficiency
    • Gottlieb MS, Schroff R, Schanker HM, Weisman JD, Fan PT, Wolf RA, et al. Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: evidence of a new acquired cellular immunodeficiency. N Engl J Med. 1981;305(24):1425-31.
    • (1981) N Engl J Med. , vol.305 , Issue.24 , pp. 1425-1431
    • Gottlieb, M.S.1    Schroff, R.2    Schanker, H.M.3    Weisman, J.D.4    Fan, P.T.5    Wolf, R.A.6
  • 2
    • 0020596551 scopus 로고
    • Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS)
    • Barre-Sinoussi F, Chermann JC, Rey F, Nugeyre MT, Chamaret S, Gruest J, et al. Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). Science. 1983;220(4599):868-71.
    • (1983) Science. , vol.220 , Issue.4599 , pp. 868-871
    • Barre-Sinoussi, F.1    Chermann, J.C.2    Rey, F.3    Nugeyre, M.T.4    Chamaret, S.5    Gruest, J.6
  • 4
    • 0023268502 scopus 로고
    • The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial
    • Fischl MA, Richman DD, Grieco MH, Gottlieb MS, Volberding PA, Laskin OL, et al. The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial. N Engl J Med. 1987;317(4):185-91.
    • (1987) N Engl J Med. , vol.317 , Issue.4 , pp. 185-191
    • Fischl, M.A.1    Richman, D.D.2    Grieco, M.H.3    Gottlieb, M.S.4    Volberding, P.A.5    Laskin, O.L.6
  • 5
    • 79959457411 scopus 로고    scopus 로고
    • Common adverse effects of antiretroviral therapy for HIV disease
    • Reust CE. Common adverse effects of antiretroviral therapy for HIV disease. Am Fam Physician. 2011;83(12):1443-51.
    • (2011) Am Fam Physician. , vol.83 , Issue.12 , pp. 1443-1451
    • Reust, C.E.1
  • 6
    • 0034956253 scopus 로고    scopus 로고
    • Mitochondrial toxicity and HIV therapy
    • White AJ. Mitochondrial toxicity and HIV therapy. Sex Transm Infect. 2001;77(3):158-73.
    • (2001) Sex Transm Infect. , vol.77 , Issue.3 , pp. 158-173
    • White, A.J.1
  • 7
    • 84890307079 scopus 로고    scopus 로고
    • Antiretroviral regimens sparing agents from the nucleoside(tide) reverse transcriptase inhibitor class: A review of the recent literature
    • Achhra AC, Boyd MA. Antiretroviral regimens sparing agents from the nucleoside(tide) reverse transcriptase inhibitor class: a review of the recent literature. AIDS Res Ther. 2013;10(1):33.
    • (2013) AIDS Res Ther. , vol.10 , Issue.1 , pp. 33
    • Achhra, A.C.1    Boyd, M.A.2
  • 8
    • 0042832397 scopus 로고    scopus 로고
    • Guidelines for the evaluation and management of dyslipidemia in human immunodeficiency virus (HIV)- infected adults receiving antiretroviral therapy: Recommendations of the HIV Medical Association of the Infectious Disease Society of America and the Adult AIDS Clinical Trials Group
    • Dube MP, Stein JH, Aberg JA, Fichtenbaum CJ, Gerber JG, Tashima KT, et al. Guidelines for the evaluation and management of dyslipidemia in human immunodeficiency virus (HIV)- infected adults receiving antiretroviral therapy: recommendations of the HIV Medical Association of the Infectious Disease Society of America and the Adult AIDS Clinical Trials Group. Clin Infect Dis. 2003;37(5):613-27.
    • (2003) Clin Infect Dis. , vol.37 , Issue.5 , pp. 613-627
    • Dube, M.P.1    Stein, J.H.2    Aberg, J.A.3    Fichtenbaum, C.J.4    Gerber, J.G.5    Tashima, K.T.6
  • 9
    • 34247537169 scopus 로고    scopus 로고
    • Class of antiretroviral drugs and the risk of myocardial infarction
    • Group DADS, Friis-Moller N, Reiss P, Sabin CA, Weber R, Monforte A, et al. Class of antiretroviral drugs and the risk of myocardial infarction. N Engl J Med. 2007;356(17): 1723-35.
    • (2007) N Engl J Med. , vol.356 , Issue.17 , pp. 1723-1735
    • Friis-Moller, N.1    Reiss, P.2    Sabin, C.A.3    Weber, R.4    Monforte, A.5
  • 10
    • 0034304841 scopus 로고    scopus 로고
    • New targets for inhibitors of HIV-1 replication
    • Moore JP, Stevenson M. New targets for inhibitors of HIV-1 replication. Nat Rev Mol Cell Biol. 2000;1(1):40-9.
    • (2000) Nat Rev Mol Cell Biol. , vol.1 , Issue.1 , pp. 40-49
    • Moore, J.P.1    Stevenson, M.2
  • 11
    • 0038299654 scopus 로고    scopus 로고
    • HIV-1 pathogenesis
    • Stevenson M. HIV-1 pathogenesis. Nat Med. 2003;9(7):853-60.
    • (2003) Nat Med. , vol.9 , Issue.7 , pp. 853-860
    • Stevenson, M.1
  • 14
    • 0023028190 scopus 로고
    • The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
    • Maddon PJ, Dalgleish AG, McDougal JS, Clapham PR, Weiss RA, Axel R. The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain. Cell. 1986;47(3):333-48.
    • (1986) Cell. , vol.47 , Issue.3 , pp. 333-348
    • Maddon, P.J.1    Dalgleish, A.G.2    McDougal, J.S.3    Clapham, P.R.4    Weiss, R.A.5    Axel, R.6
  • 15
    • 0022587282 scopus 로고
    • Binding of HTLVIII/ LAV to T4+ T cells by a complex of the 110 K viral protein and the T4 molecule
    • McDougal JS, Kennedy MS, Sligh JM, Cort SP, Mawle A, Nicholson JK. Binding of HTLVIII/ LAV to T4+ T cells by a complex of the 110 K viral protein and the T4 molecule. Science. 1986;231(4736):382-5.
    • (1986) Science. , vol.231 , Issue.4736 , pp. 382-385
    • McDougal, J.S.1    Kennedy, M.S.2    Sligh, J.M.3    Cort, S.P.4    Mawle, A.5    Nicholson, J.K.6
  • 16
    • 0030018156 scopus 로고    scopus 로고
    • CC CKR5: A RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1
    • Alkhatib G, Combadiere C, Broder CC, Feng Y, Kennedy PE, Murphy PM, et al. CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1. Science. 1996;272(5270):1955-8.
    • (1996) Science. , vol.272 , Issue.5270 , pp. 1955-1958
    • Alkhatib, G.1    Combadiere, C.2    Broder, C.C.3    Feng, Y.4    Kennedy, P.E.5    Murphy, P.M.6
  • 17
    • 0005014748 scopus 로고    scopus 로고
    • The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates
    • Choe H, Farzan M, Sun Y, Sullivan N, Rollins B, Ponath PD, et al. The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell. 1996; 85(7):1135-48.
    • (1996) Cell. , vol.85 , Issue.7 , pp. 1135-1148
    • Choe, H.1    Farzan, M.2    Sun, Y.3    Sullivan, N.4    Rollins, B.5    Ponath, P.D.6
  • 18
    • 15844419153 scopus 로고    scopus 로고
    • Identification of a major co-receptor for primary isolates of HIV-1
    • Deng H, Liu R, Ellmeier W, Choe S, Unutmaz D, Burkhart M, et al. Identification of a major co-receptor for primary isolates of HIV-1. Nature. 1996;381(6584):661-6.
    • (1996) Nature. , vol.381 , Issue.6584 , pp. 661-666
    • Deng, H.1    Liu, R.2    Ellmeier, W.3    Choe, S.4    Unutmaz, D.5    Burkhart, M.6
  • 19
    • 15844389650 scopus 로고    scopus 로고
    • HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
    • Dragic T, Litwin V, Allaway GP, Martin SR, Huang Y, Nagashima KA, et al. HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature. 1996;381(6584): 667-73.
    • (1996) Nature. , vol.381 , Issue.6584 , pp. 667-673
    • Dragic, T.1    Litwin, V.2    Allaway, G.P.3    Martin, S.R.4    Huang, Y.5    Nagashima, K.A.6
  • 20
    • 0030002637 scopus 로고    scopus 로고
    • HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
    • Feng Y, Broder CC, Kennedy PE, Berger EA. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science. 1996;272(5263):872-7.
    • (1996) Science. , vol.272 , Issue.5263 , pp. 872-877
    • Feng, Y.1    Broder, C.C.2    Kennedy, P.E.3    Berger, E.A.4
  • 22
    • 0027983799 scopus 로고
    • Purification by DNA affinity chromatography of two polypeptides that contact the NF-AT DNA binding site in the interleukin 2 promoter
    • Corthesy B, Kao PN. Purification by DNA affinity chromatography of two polypeptides that contact the NF-AT DNA binding site in the interleukin 2 promoter. J Biol Chem. 1994; 269(32):20682-90.
    • (1994) J Biol Chem. , vol.269 , Issue.32 , pp. 20682-20690
    • Corthesy, B.1    Kao, P.N.2
  • 23
    • 0022541602 scopus 로고
    • Activation of the AIDS retrovirus promoter by the cellular transcription factor, Sp1
    • Jones KA, Kadonaga JT, Luciw PA, Tjian R. Activation of the AIDS retrovirus promoter by the cellular transcription factor, Sp1. Science. 1986;232(4751):755-9.
    • (1986) Science. , vol.232 , Issue.4751 , pp. 755-759
    • Jones, K.A.1    Kadonaga, J.T.2    Luciw, P.A.3    Tjian, R.4
  • 24
    • 0023176085 scopus 로고
    • An inducible transcription factor activates expression of human immunodeficiency virus in T cells
    • Nabel G, Baltimore D. An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature. 1987;326(6114):711-3.
    • (1987) Nature. , vol.326 , Issue.6114 , pp. 711-713
    • Nabel, G.1    Baltimore, D.2
  • 25
    • 0032450548 scopus 로고    scopus 로고
    • HIV-1 Tat interacts with cyclin T1 to direct the P-TEFb CTD kinase complex to TAR RNA
    • Garber ME, Wei P, Jones KA. HIV-1 Tat interacts with cyclin T1 to direct the P-TEFb CTD kinase complex to TAR RNA. Cold Spring Harb Symp Quant Biol. 1998;63:371-80.
    • (1998) Cold Spring Harb Symp Quant Biol. , vol.63 , pp. 371-380
    • Garber, M.E.1    Wei, P.2    Jones, K.A.3
  • 26
    • 83455250659 scopus 로고    scopus 로고
    • Role of the nucleolus in HIV infection and therapy
    • Olson MOJ, editor. Springer: New York
    • Arizala JR, Rossi JJ. Role of the nucleolus in HIV infection and therapy. In: Olson MOJ, editor. The nucleolus. Protein reviews. Springer: New York; 2011. p. 381-402.
    • (2011) The nucleolus. Protein reviews. , pp. 381-402
    • Arizala, J.R.1    Rossi, J.J.2
  • 29
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 1998;391(6669): 806-11.
    • (1998) Nature. , vol.391 , Issue.6669 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 30
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21- nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21- nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 2001;411(6836):494-8.
    • (2001) Nature. , vol.411 , Issue.6836 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 31
    • 33751099034 scopus 로고    scopus 로고
    • RNAi therapeutics: A potential new class of pharmaceutical drugs
    • Bumcrot D, Manoharan M, Koteliansky V, Sah DW. RNAi therapeutics: a potential new class of pharmaceutical drugs. Nat Chem Biol. 2006;2(12):711-9.
    • (2006) Nat Chem Biol. , vol.2 , Issue.12 , pp. 711-719
    • Bumcrot, D.1    Manoharan, M.2    Koteliansky, V.3    Sah, D.W.4
  • 32
    • 58749104364 scopus 로고    scopus 로고
    • The promises and pitfalls of RNA-interference-based therapeutics
    • Castanotto D, Rossi JJ. The promises and pitfalls of RNA-interference-based therapeutics. Nature. 2009;457(7228):426-33.
    • (2009) Nature. , vol.457 , Issue.7228 , pp. 426-433
    • Castanotto, D.1    Rossi, J.J.2
  • 33
    • 14544280255 scopus 로고    scopus 로고
    • The silent revolution: RNA interference as basic biology, research tool, and therapeutic
    • Dykxhoorn DM, Lieberman J. The silent revolution: RNA interference as basic biology, research tool, and therapeutic. Annu Rev Med. 2005;56:401-23.
    • (2005) Annu Rev Med. , vol.56 , pp. 401-423
    • Dykxhoorn, D.M.1    Lieberman, J.2
  • 34
    • 36849042601 scopus 로고    scopus 로고
    • RNA interference against viruses: Strike and counterstrike
    • Haasnoot J, Westerhout EM, Berkhout B. RNA interference against viruses: strike and counterstrike. Nat Biotechnol. 2007;25(12):1435-43.
    • (2007) Nat Biotechnol. , vol.25 , Issue.12 , pp. 1435-1443
    • Haasnoot, J.1    Westerhout, E.M.2    Berkhout, B.3
  • 35
    • 64549124403 scopus 로고    scopus 로고
    • Progress in the therapeutic applications of siRNAs against HIV-1
    • Martinez MA. Progress in the therapeutic applications of siRNAs against HIV-1. Methods Mol Biol. 2009;487:343-68.
    • (2009) Methods Mol Biol. , vol.487 , pp. 343-368
    • Martinez, M.A.1
  • 36
    • 76149120462 scopus 로고    scopus 로고
    • RNA interference-based therapeutics for human immunodeficiency virus HIV-1 treatment: Synthetic siRNA or vector-based shRNA?
    • Subramanya S, Kim SS, Manjunath N, Shankar P. RNA interference-based therapeutics for human immunodeficiency virus HIV-1 treatment: synthetic siRNA or vector-based shRNA? Expert Opin Biol Ther. 2010;10(2):201-13.
    • (2010) Expert Opin Biol Ther. , vol.10 , Issue.2 , pp. 201-213
    • Subramanya, S.1    Kim, S.S.2    Manjunath, N.3    Shankar, P.4
  • 37
    • 77951603925 scopus 로고    scopus 로고
    • RNA interference: Homing in on delivery
    • Baker M. RNA interference: Homing in on delivery. Nature. 2010;464(7292):1225-8.
    • (2010) Nature. , vol.464 , Issue.7292 , pp. 1225-1228
    • Baker, M.1
  • 38
    • 38449100768 scopus 로고    scopus 로고
    • Small RNAs: Delivering the future
    • Blow N. Small RNAs: delivering the future. Nature. 2007;450(7172):1117-20.
    • (2007) Nature. , vol.450 , Issue.7172 , pp. 1117-1120
    • Blow, N.1
  • 39
    • 80052627990 scopus 로고    scopus 로고
    • Current progress of siRNA/shRNA therapeutics in clinical trials
    • Epub 2011/07/12
    • Burnett JC, Rossi JJ, Tiemann K. Current progress of siRNA/shRNA therapeutics in clinical trials. Biotechnol J. 2011;6(9):1130-46. Epub 2011/07/12.
    • (2011) Biotechnol J. , vol.6 , Issue.9 , pp. 1130-1146
    • Burnett, J.C.1    Rossi, J.J.2    Tiemann, K.3
  • 40
    • 79954580272 scopus 로고    scopus 로고
    • Current prospects for RNA interference-based therapies
    • Davidson BL, McCray Jr PB. Current prospects for RNA interference-based therapies. Nat Rev Genet. 2011;12(5):329-40.
    • (2011) Nat Rev Genet. , vol.12 , Issue.5 , pp. 329-340
    • Davidson, B.L.1    McCray, P.B.2
  • 41
    • 58449134534 scopus 로고    scopus 로고
    • Small silencing RNAs: An expanding universe
    • Ghildiyal M, Zamore PD. Small silencing RNAs: an expanding universe. Nat Rev Genet. 2009;10(2):94-108.
    • (2009) Nat Rev Genet. , vol.10 , Issue.2 , pp. 94-108
    • Ghildiyal, M.1    Zamore, P.D.2
  • 44
  • 46
    • 33751511117 scopus 로고    scopus 로고
    • Gene expression analysis in blood cells in response to unmodified and 2'-modified siRNAs reveals TLR-dependent and independent effects
    • Cekaite L, Furset G, Hovig E, Sioud M. Gene expression analysis in blood cells in response to unmodified and 2'-modified siRNAs reveals TLR-dependent and independent effects. J Mol Biol. 2007;365(1):90-108.
    • (2007) J Mol Biol. , vol.365 , Issue.1 , pp. 90-108
    • Cekaite, L.1    Furset, G.2    Hovig, E.3    Sioud, M.4
  • 47
    • 20144389695 scopus 로고    scopus 로고
    • Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7
    • Hornung V, Guenthner-Biller M, Bourquin C, Ablasser A, Schlee M, Uematsu S, et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005;11(3):263-70.
    • (2005) Nat Med. , vol.11 , Issue.3 , pp. 263-270
    • Hornung, V.1    Guenthner-Biller, M.2    Bourquin, C.3    Ablasser, A.4    Schlee, M.5    Uematsu, S.6
  • 48
    • 32944454941 scopus 로고    scopus 로고
    • Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo
    • Judge AD, Bola G, Lee AC, MacLachlan I. Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo. Mol Ther. 2006;13(3):494-505.
    • (2006) Mol Ther. , vol.13 , Issue.3 , pp. 494-505
    • Judge, A.D.1    Bola, G.2    Lee, A.C.3    McLachlan, I.4
  • 49
    • 23844464444 scopus 로고    scopus 로고
    • Suppression of RNA recognition by Toll-like receptors: The impact of nucleoside modification and the evolutionary origin of RNA
    • Kariko K, Buckstein M, Ni H, Weissman D. Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA. Immunity. 2005;23(2):165-75.
    • (2005) Immunity. , vol.23 , Issue.2 , pp. 165-175
    • Kariko, K.1    Buckstein, M.2    Ni, H.3    Weissman, D.4
  • 51
    • 33646544416 scopus 로고    scopus 로고
    • Single-stranded small interfering RNA are more immunostimulatory than their double-stranded counterparts: A central role for 2′-hydroxyl uridines in immune responses
    • Sioud M. Single-stranded small interfering RNA are more immunostimulatory than their double-stranded counterparts: a central role for 2′-hydroxyl uridines in immune responses. Eur J Immunol. 2006;36(5):1222-30.
    • (2006) Eur J Immunol. , vol.36 , Issue.5 , pp. 1222-1230
    • Sioud, M.1
  • 53
    • 0036839458 scopus 로고    scopus 로고
    • Inhibition of HIV-1 infection by small interfering RNAmediated RNA interference
    • Capodici J, Kariko K, Weissman D. Inhibition of HIV-1 infection by small interfering RNAmediated RNA interference. J Immunol. 2002;169(9):5196-201.
    • (2002) J Immunol. , vol.169 , Issue.9 , pp. 5196-5201
    • Capodici, J.1    Kariko, K.2    Weissman, D.3
  • 55
    • 33751001588 scopus 로고    scopus 로고
    • Silencing of HIV-1 with RNA interference: A multiple shRNA approach
    • ter Brake O, Konstantinova P, Ceylan M, Berkhout B. Silencing of HIV-1 with RNA interference: a multiple shRNA approach. Mol Ther. 2006;14(6):883-92.
    • (2006) Mol Ther. , vol.14 , Issue.6 , pp. 883-892
    • ter Brake, O.1    Konstantinova, P.2    Ceylan, M.3    Berkhout, B.4
  • 56
    • 34648827818 scopus 로고    scopus 로고
    • Endoribonuclease-prepared short interfering RNAs induce effective and specific inhibition of human immunodeficiency virus type 1 replication
    • Gimenez-Barcons M, Clotet B, Martinez MA. Endoribonuclease-prepared short interfering RNAs induce effective and specific inhibition of human immunodeficiency virus type 1 replication. J Virol. 2007;81(19):10680-6.
    • (2007) J Virol. , vol.81 , Issue.19 , pp. 10680-10686
    • Gimenez-Barcons, M.1    Clotet, B.2    Martinez, M.A.3
  • 57
    • 30344474936 scopus 로고    scopus 로고
    • Sequence homology required by human immunodeficiency virus type 1 to escape from short interfering RNAs
    • Sabariegos R, Gimenez-Barcons M, Tapia N, Clotet B, Martinez MA. Sequence homology required by human immunodeficiency virus type 1 to escape from short interfering RNAs. J Virol. 2006;80(2):571-7.
    • (2006) J Virol. , vol.80 , Issue.2 , pp. 571-577
    • Sabariegos, R.1    Gimenez-Barcons, M.2    Tapia, N.3    Clotet, B.4    Martinez, M.A.5
  • 58
    • 0036721314 scopus 로고    scopus 로고
    • Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference
    • Coburn GA, Cullen BR. Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference. J Virol. 2002;76(18):9225-31.
    • (2002) J Virol. , vol.76 , Issue.18 , pp. 9225-9231
    • Coburn, G.A.1    Cullen, B.R.2
  • 59
    • 0036256430 scopus 로고    scopus 로고
    • Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
    • Lee NS, Dohjima T, Bauer G, Li H, Li MJ, Ehsani A, et al. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat Biotechnol. 2002;20(5): 500-5.
    • (2002) Nat Biotechnol. , vol.20 , Issue.5 , pp. 500-505
    • Lee, N.S.1    Dohjima, T.2    Bauer, G.3    Li, H.4    Li, M.J.5    Ehsani, A.6
  • 60
    • 37549037041 scopus 로고    scopus 로고
    • Expression of long anti-HIV-1 hairpin RNAs for the generation of multiple siRNAs: Advantages and limitations
    • Sano M, Li H, Nakanishi M, Rossi JJ. Expression of long anti-HIV-1 hairpin RNAs for the generation of multiple siRNAs: advantages and limitations. Mol Ther. 2008;16(1):170-7.
    • (2008) Mol Ther. , vol.16 , Issue.1 , pp. 170-177
    • Sano, M.1    Li, H.2    Nakanishi, M.3    Rossi, J.J.4
  • 61
    • 23044517213 scopus 로고    scopus 로고
    • Lentiviral delivery of short hairpin RNAs protects CD4 T cells from multiple clades and primary isolates of HIV
    • Lee SK, Dykxhoorn DM, Kumar P, Ranjbar S, Song E, Maliszewski LE, et al. Lentiviral delivery of short hairpin RNAs protects CD4 T cells from multiple clades and primary isolates of HIV. Blood. 2005;106(3):818-26.
    • (2005) Blood. , vol.106 , Issue.3 , pp. 818-826
    • Lee, S.K.1    Dykxhoorn, D.M.2    Kumar, P.3    Ranjbar, S.4    Song, E.5    Maliszewski, L.E.6
  • 62
    • 33748850724 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus type 1 by RNA interference using long-hairpin RNA
    • Konstantinova P, de Vries W, Haasnoot J, ter Brake O, de Haan P, Berkhout B. Inhibition of human immunodeficiency virus type 1 by RNA interference using long-hairpin RNA. Gene Ther. 2006;13(19):1403-13.
    • (2006) Gene Ther. , vol.13 , Issue.19 , pp. 1403-1413
    • Konstantinova, P.1    de Vries, W.2    Haasnoot, J.3    ter Brake, O.4    de Haan, P.5    Berkhout, B.6
  • 63
    • 0037173610 scopus 로고    scopus 로고
    • Modulation of HIV-1 replication by RNA interference
    • Jacque JM, Triques K, Stevenson M. Modulation of HIV-1 replication by RNA interference. Nature. 2002;418(6896):435-8.
    • (2002) Nature. , vol.418 , Issue.6896 , pp. 435-438
    • Jacque, J.M.1    Triques, K.2    Stevenson, M.3
  • 64
    • 0029075130 scopus 로고
    • Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase
    • Mansky LM, Temin HM. Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase. J Virol. 1995; 69(8):5087-94.
    • (1995) J Virol. , vol.69 , Issue.8 , pp. 5087-5094
    • Mansky, L.M.1    Temin, H.M.2
  • 65
    • 0142124143 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 escape from RNA interference
    • Boden D, Pusch O, Lee F, Tucker L, Ramratnam B. Human immunodeficiency virus type 1 escape from RNA interference. J Virol. 2003;77(21):11531-5.
    • (2003) J Virol. , vol.77 , Issue.21 , pp. 11531-11535
    • Boden, D.1    Pusch, O.2    Lee, F.3    Tucker, L.4    Ramratnam, B.5
  • 66
    • 1242319384 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition
    • Das AT, Brummelkamp TR, Westerhout EM, Vink M, Madiredjo M, Bernards R, et al. Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition. J Virol. 2004;78(5):2601-5.
    • (2004) J Virol. , vol.78 , Issue.5 , pp. 2601-2605
    • Das, A.T.1    Brummelkamp, T.R.2    Westerhout, E.M.3    Vink, M.4    Madiredjo, M.5    Bernards, R.6
  • 67
    • 13844320402 scopus 로고    scopus 로고
    • HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome
    • Westerhout EM, Ooms M, Vink M, Das AT, Berkhout B. HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome. Nucleic Acids Res. 2005; 33(2):796-804.
    • (2005) Nucleic Acids Res. , vol.33 , Issue.2 , pp. 796-804
    • Westerhout, E.M.1    Ooms, M.2    Vink, M.3    Das, A.T.4    Berkhout, B.5
  • 68
    • 77957807722 scopus 로고    scopus 로고
    • Deriving four functional anti-HIV siRNAs from a single Pol III-generated transcript comprising two adjacent long hairpin RNA precursors
    • Saayman S, Arbuthnot P, Weinberg MS. Deriving four functional anti-HIV siRNAs from a single Pol III-generated transcript comprising two adjacent long hairpin RNA precursors. Nucleic Acids Res. 2010;38(19):6652-63.
    • (2010) Nucleic Acids Res. , vol.38 , Issue.19 , pp. 6652-6663
    • Saayman, S.1    Arbuthnot, P.2    Weinberg, M.S.3
  • 69
    • 49749095063 scopus 로고    scopus 로고
    • The efficacy of generating three independent anti-HIV-1 siRNAs from a single U6 RNA Pol III-expressed long hairpin RNA
    • Saayman S, Barichievy S, Capovilla A, Morris KV, Arbuthnot P, Weinberg MS. The efficacy of generating three independent anti-HIV-1 siRNAs from a single U6 RNA Pol III-expressed long hairpin RNA. PLoS One. 2008;3(7):e2602.
    • (2008) PLoS One. , vol.3 , Issue.7
    • Saayman, S.1    Barichievy, S.2    Capovilla, A.3    Morris, K.V.4    Arbuthnot, P.5    Weinberg, M.S.6
  • 70
    • 77954077844 scopus 로고    scopus 로고
    • Effective Pol III-expressed long hairpin RNAs targeted to multiple unique sites of HIV-1
    • Saayman SM, Arbuthnot P, Weinberg MS. Effective Pol III-expressed long hairpin RNAs targeted to multiple unique sites of HIV-1. Methods Mol Biol. 2010;629:159-74.
    • (2010) Methods Mol Biol. , vol.629 , pp. 159-174
    • Saayman, S.M.1    Arbuthnot, P.2    Weinberg, M.S.3
  • 72
    • 1642564331 scopus 로고    scopus 로고
    • Bispecific short hairpin siRNA constructs targeted to CD4, CXCR4, and CCR5 confer HIV-1 resistance
    • Anderson J, Banerjea A, Akkina R. Bispecific short hairpin siRNA constructs targeted to CD4, CXCR4, and CCR5 confer HIV-1 resistance. Oligonucleotides. 2003;13(5):303-12.
    • (2003) Oligonucleotides. , vol.13 , Issue.5 , pp. 303-312
    • Anderson, J.1    Banerjea, A.2    Akkina, R.3
  • 73
    • 82955237641 scopus 로고    scopus 로고
    • Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice
    • Epub 2011/09/29
    • Zhou J, Neff CP, Liu X, Zhang J, Li H, Smith DD, et al. Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice. Mol Ther. 2011;19(12):2228-38. Epub 2011/09/29.
    • (2011) Mol Ther. , vol.19 , Issue.12 , pp. 2228-2238
    • Zhou, J.1    Neff, C.P.2    Liu, X.3    Zhang, J.4    Li, H.5    Smith, D.D.6
  • 74
    • 33845221484 scopus 로고    scopus 로고
    • HIV-1 resistance conferred by siRNA cosuppression of CXCR4 and CCR5 coreceptors by a bispecific lentiviral vector
    • Anderson J, Akkina R. HIV-1 resistance conferred by siRNA cosuppression of CXCR4 and CCR5 coreceptors by a bispecific lentiviral vector. AIDS Res Ther. 2005;2(1):1.
    • (2005) AIDS Res Ther. , vol.2 , Issue.1 , pp. 1
    • Anderson, J.1    Akkina, R.2
  • 75
    • 77349124962 scopus 로고    scopus 로고
    • Inhibition of HIV-1 infection by a unique short hairpin RNA to chemokine receptor 5 delivered into macrophages through hematopoietic progenitor cell transduction
    • Liang M, Kamata M, Chen KN, Pariente N, An DS, Chen IS. Inhibition of HIV-1 infection by a unique short hairpin RNA to chemokine receptor 5 delivered into macrophages through hematopoietic progenitor cell transduction. J Gene Med. 2010;12(3):255-65.
    • (2010) J Gene Med. , vol.12 , Issue.3 , pp. 255-265
    • Liang, M.1    Kamata, M.2    Chen, K.N.3    Pariente, N.4    An, D.S.5    Chen, I.S.6
  • 76
    • 0037422583 scopus 로고    scopus 로고
    • Inhibiting HIV-1 infection in human T cells by lentiviral- mediated delivery of small interfering RNA against CCR5
    • Qin XF, An DS, Chen IS, Baltimore D. Inhibiting HIV-1 infection in human T cells by lentiviral- mediated delivery of small interfering RNA against CCR5. Proc Natl Acad Sci U S A. 2003;100(1):183-8.
    • (2003) Proc Natl Acad Sci U S A. , vol.100 , Issue.1 , pp. 183-188
    • Qin, X.F.1    An, D.S.2    Chen, I.S.3    Baltimore, D.4
  • 77
    • 9944222768 scopus 로고    scopus 로고
    • Inhibition of HIV-1 fusion with small interfering RNAs targeting the chemokine coreceptor CXCR4
    • Zhou N, Fang J, Mukhtar M, Acheampong E, Pomerantz RJ. Inhibition of HIV-1 fusion with small interfering RNAs targeting the chemokine coreceptor CXCR4. Gene Ther. 2004; 11(23):1703-12.
    • (2004) Gene Ther. , vol.11 , Issue.23 , pp. 1703-1712
    • Zhou, N.1    Fang, J.2    Mukhtar, M.3    Acheampong, E.4    Pomerantz, R.J.5
  • 78
    • 0036891843 scopus 로고    scopus 로고
    • RNA interference directed against viral and cellular targets inhibits human immunodeficiency Virus Type 1 replication
    • Surabhi RM, Gaynor RB. RNA interference directed against viral and cellular targets inhibits human immunodeficiency Virus Type 1 replication. J Virol. 2002;76(24):12963-73.
    • (2002) J Virol. , vol.76 , Issue.24 , pp. 12963-12973
    • Surabhi, R.M.1    Gaynor, R.B.2
  • 79
    • 1242342082 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus type 1 replication by RNA interference directed against human transcription elongation factor P-TEFb (CDK9/CyclinT1)
    • Chiu YL, Cao H, Jacque JM, Stevenson M, Rana TM. Inhibition of human immunodeficiency virus type 1 replication by RNA interference directed against human transcription elongation factor P-TEFb (CDK9/CyclinT1). J Virol. 2004;78(5):2517-29.
    • (2004) J Virol. , vol.78 , Issue.5 , pp. 2517-2529
    • Chiu, Y.L.1    Cao, H.2    Jacque, J.M.3    Stevenson, M.4    Rana, T.M.5
  • 80
    • 39349097864 scopus 로고    scopus 로고
    • Identification of host proteins required for HIV infection through a functional genomic screen
    • Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman A, Xavier RJ, et al. Identification of host proteins required for HIV infection through a functional genomic screen. Science. 2008;319(5865):921-6.
    • (2008) Science. , vol.319 , Issue.5865 , pp. 921-926
    • Brass, A.L.1    Dykxhoorn, D.M.2    Benita, Y.3    Yan, N.4    Engelman, A.5    Xavier, R.J.6
  • 81
    • 60549090253 scopus 로고    scopus 로고
    • Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
    • Hutter G, Nowak D, Mossner M, Ganepola S, Mussig A, Allers K, et al. Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N Engl J Med. 2009; 360(7):692-8.
    • (2009) N Engl J Med. , vol.360 , Issue.7 , pp. 692-698
    • Hutter, G.1    Nowak, D.2    Mossner, M.3    Ganepola, S.4    Mussig, A.5    Allers, K.6
  • 82
    • 77955608799 scopus 로고    scopus 로고
    • RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma
    • DiGiusto DL, Krishnan A, Li L, Li H, Li S, Rao A, et al. RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma. Sci Transl Med. 2010;2(36):36ra43.
    • (2010) Sci Transl Med. , vol.2 , Issue.36
    • DiGiusto, D.L.1    Krishnan, A.2    Li, L.3    Li, H.4    Li, S.5    Rao, A.6
  • 83
    • 10744228940 scopus 로고    scopus 로고
    • Inhibition of HIV-1 infection by lentiviral vectors expressing Pol III-promoted anti-HIV RNAs
    • Epub 2003/08/09
    • Li MJ, Bauer G, Michienzi A, Yee JK, Lee NS, Kim J, et al. Inhibition of HIV-1 infection by lentiviral vectors expressing Pol III-promoted anti-HIV RNAs. Mol Ther. 2003;8(2):196-206. Epub 2003/08/09.
    • (2003) Mol Ther. , vol.8 , Issue.2 , pp. 196-206
    • Li, M.J.1    Bauer, G.2    Michienzi, A.3    Yee, J.K.4    Lee, N.S.5    Kim, J.6
  • 84
    • 84904532943 scopus 로고    scopus 로고
    • Transplantation in HIV-infected subjects: Is cure possible?
    • Zaia JA, Forman SJ. Transplantation in HIV-infected subjects: is cure possible? Hematol Am Soc Hematol Educ Program. 2013;2013:389-93.
    • (2013) Hematol Am Soc Hematol Educ Program. , vol.2013 , pp. 389-393
    • Zaia, J.A.1    Forman, S.J.2
  • 85
    • 23844474160 scopus 로고    scopus 로고
    • Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors
    • Song E, Zhu P, Lee SK, Chowdhury D, Kussman S, Dykxhoorn DM, et al. Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. Nat Biotechnol. 2005;23(6):709-17.
    • (2005) Nat Biotechnol. , vol.23 , Issue.6 , pp. 709-717
    • Song, E.1    Zhu, P.2    Lee, S.K.3    Chowdhury, D.4    Kussman, S.5    Dykxhoorn, D.M.6
  • 86
    • 49549117077 scopus 로고    scopus 로고
    • T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice
    • Kumar P, Ban HS, Kim SS, Wu H, Pearson T, Greiner DL, et al. T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice. Cell. 2008;134(4):577-86.
    • (2008) Cell. , vol.134 , Issue.4 , pp. 577-586
    • Kumar, P.1    Ban, H.S.2    Kim, S.S.3    Wu, H.4    Pearson, T.5    Greiner, D.L.6
  • 87
    • 34247255870 scopus 로고    scopus 로고
    • Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1
    • Peer D, Zhu P, Carman CV, Lieberman J, Shimaoka M. Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1. Proc Natl Acad Sci U S A. 2007;104(10):4095-100.
    • (2007) Proc Natl Acad Sci U S A. , vol.104 , Issue.10 , pp. 4095-4100
    • Peer, D.1    Zhu, P.2    Carman, C.V.3    Lieberman, J.4    Shimaoka, M.5
  • 88
    • 76349095131 scopus 로고    scopus 로고
    • RNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice
    • Kim SS, Peer D, Kumar P, Subramanya S, Wu H, Asthana D, et al. RNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice. Mol Ther. 2010;18(2):370-6.
    • (2010) Mol Ther. , vol.18 , Issue.2 , pp. 370-376
    • Kim, S.S.1    Peer, D.2    Kumar, P.3    Subramanya, S.4    Wu, H.5    Asthana, D.6
  • 89
    • 67149093390 scopus 로고    scopus 로고
    • Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein
    • Eguchi A, Meade BR, Chang YC, Fredrickson CT, Willert K, Puri N, et al. Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein. Nat Biotechnol. 2009;27(6):567-71.
    • (2009) Nat Biotechnol. , vol.27 , Issue.6 , pp. 567-571
    • Eguchi, A.1    Meade, B.R.2    Chang, Y.C.3    Fredrickson, C.T.4    Willert, K.5    Puri, N.6
  • 90
    • 84890401599 scopus 로고    scopus 로고
    • Current progress on aptamer-targeted oligonucleotide therapeutics
    • Dassie JP, Giangrande PH. Current progress on aptamer-targeted oligonucleotide therapeutics. Ther Deliv. 2013;4(12):1527-46.
    • (2013) Ther Deliv. , vol.4 , Issue.12 , pp. 1527-1546
    • Dassie, J.P.1    Giangrande, P.H.2
  • 91
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • Ellington AD, Szostak JW. In vitro selection of RNA molecules that bind specific ligands. Nature. 1990;346(6287):818-22.
    • (1990) Nature. , vol.346 , Issue.6287 , pp. 818-822
    • Ellington, A.D.1    Szostak, J.W.2
  • 92
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
    • Tuerk C, Gold L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science. 1990;249(4968):505-10.
    • (1990) Science. , vol.249 , Issue.4968 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 93
    • 34548551398 scopus 로고    scopus 로고
    • SELEX-a (r)evolutionary method to generate high-affinity nucleic acid ligands
    • Stoltenburg R, Reinemann C, Strehlitz B. SELEX-a (r)evolutionary method to generate high-affinity nucleic acid ligands. Biomol Eng. 2007;24(4):381-403.
    • (2007) Biomol Eng. , vol.24 , Issue.4 , pp. 381-403
    • Stoltenburg, R.1    Reinemann, C.2    Strehlitz, B.3
  • 95
    • 26644474798 scopus 로고    scopus 로고
    • Deconvolution of a complex target using DNA aptamers
    • Fitter S, James R. Deconvolution of a complex target using DNA aptamers. J Biol Chem. 2005;280(40):34193-201.
    • (2005) J Biol Chem. , vol.280 , Issue.40 , pp. 34193-34201
    • Fitter, S.1    James, R.2
  • 96
    • 0035844150 scopus 로고    scopus 로고
    • Systematic evolution of a DNA aptamer binding to rat brain tumor microvessels selective targeting of endothelial regulatory protein pigpen
    • Blank M, Weinschenk T, Priemer M, Schluesener H. Systematic evolution of a DNA aptamer binding to rat brain tumor microvessels selective targeting of endothelial regulatory protein pigpen. J Biol Chem. 2001;276(19):16464-8.
    • (2001) J Biol Chem. , vol.276 , Issue.19 , pp. 16464-16468
    • Blank, M.1    Weinschenk, T.2    Priemer, M.3    Schluesener, H.4
  • 97
    • 18344375927 scopus 로고    scopus 로고
    • Neutralizing aptamers from whole-cell SELEX inhibit the RET receptor tyrosine kinase
    • Cerchia L, Duconge F, Pestourie C, Boulay J, Aissouni Y, Gombert K, et al. Neutralizing aptamers from whole-cell SELEX inhibit the RET receptor tyrosine kinase. PLoS Biol. 2005;3(4):e123.
    • (2005) PLoS Biol. , vol.3 , Issue.4
    • Cerchia, L.1    Duconge, F.2    Pestourie, C.3    Boulay, J.4    Aissouni, Y.5    Gombert, K.6
  • 98
    • 0347364648 scopus 로고    scopus 로고
    • A tenascin-C aptamer identified by tumor cell SELEX: Systematic evolution of ligands by exponential enrichment
    • Daniels DA, Chen H, Hicke BJ, Swiderek KM, Gold L. A tenascin-C aptamer identified by tumor cell SELEX: systematic evolution of ligands by exponential enrichment. Proc Natl Acad Sci U S A. 2003;100(26):15416-21.
    • (2003) Proc Natl Acad Sci U S A. , vol.100 , Issue.26 , pp. 15416-15421
    • Daniels, D.A.1    Chen, H.2    Hicke, B.J.3    Swiderek, K.M.4    Gold, L.5
  • 99
    • 43049143065 scopus 로고    scopus 로고
    • CELL-SELEX: Novel perspectives of aptamer-based therapeutics
    • Guo KT, Ziemer G, Paul A, Wendel HP. CELL-SELEX: novel perspectives of aptamer-based therapeutics. Int J Mol Sci. 2008;9(4):668-78.
    • (2008) Int J Mol Sci. , vol.9 , Issue.4 , pp. 668-678
    • Guo, K.T.1    Ziemer, G.2    Paul, A.3    Wendel, H.P.4
  • 102
    • 38849155858 scopus 로고    scopus 로고
    • Identification of liver cancerspecific aptamers using whole live cells
    • Shangguan D, Meng L, Cao ZC, Xiao Z, Fang X, Li Y, et al. Identification of liver cancerspecific aptamers using whole live cells. Anal Chem. 2008;80(3):721-8.
    • (2008) Anal Chem. , vol.80 , Issue.3 , pp. 721-728
    • Shangguan, D.1    Meng, L.2    Cao, Z.C.3    Xiao, Z.4    Fang, X.5    Li, Y.6
  • 104
    • 84866049117 scopus 로고    scopus 로고
    • Rapid identification of cellspecific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selection
    • Thiel WH, Bair T, Peek AS, Liu X, Dassie J, Stockdale KR, et al. Rapid identification of cellspecific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selection. PLoS One. 2012;7(9):e43836.
    • (2012) PLoS One. , vol.7 , Issue.9
    • Thiel, W.H.1    Bair, T.2    Peek, A.S.3    Liu, X.4    Dassie, J.5    Stockdale, K.R.6
  • 107
    • 0030854581 scopus 로고    scopus 로고
    • Mechanism of ribose 2′-group discrimination by an RNA polymerase
    • Huang Y, Eckstein F, Padilla R, Sousa R. Mechanism of ribose 2′-group discrimination by an RNA polymerase. Biochemistry. 1997;36(27):8231-42.
    • (1997) Biochemistry. , vol.36 , Issue.27 , pp. 8231-8242
    • Huang, Y.1    Eckstein, F.2    Padilla, R.3    Sousa, R.4
  • 108
    • 0033559119 scopus 로고    scopus 로고
    • Efficient synthesis of nucleic acids heavily modified with non-canonical ribose 2'-groups using a mutantT7 RNA polymerase (RNAP)
    • Padilla R, Sousa R. Efficient synthesis of nucleic acids heavily modified with non-canonical ribose 2'-groups using a mutantT7 RNA polymerase (RNAP). Nucleic Acids Res. 1999; 27(6):1561-3.
    • (1999) Nucleic Acids Res. , vol.27 , Issue.6 , pp. 1561-1563
    • Padilla, R.1    Sousa, R.2
  • 109
    • 0029091457 scopus 로고
    • A mutant T7 RNA polymerase as a DNA polymerase
    • Sousa R, Padilla R. A mutant T7 RNA polymerase as a DNA polymerase. EMBO J. 1995;14(18):4609-21.
    • (1995) EMBO J. , vol.14 , Issue.18 , pp. 4609-4621
    • Sousa, R.1    Padilla, R.2
  • 110
    • 4444326623 scopus 로고    scopus 로고
    • Evolution of a T7 RNA polymerase variant that transcribes 2′-O-methyl RNA
    • Chelliserrykattil J, Ellington AD. Evolution of a T7 RNA polymerase variant that transcribes 2′-O-methyl RNA. Nat Biotechnol. 2004;22(9):1155-60.
    • (2004) Nat Biotechnol. , vol.22 , Issue.9 , pp. 1155-1160
    • Chelliserrykattil, J.1    Ellington, A.D.2
  • 111
    • 1242314258 scopus 로고    scopus 로고
    • Expanding the substrate repertoire of a DNA polymerase by directed evolution
    • Fa M, Radeghieri A, Henry AA, Romesberg FE. Expanding the substrate repertoire of a DNA polymerase by directed evolution. J Am Chem Soc. 2004;126(6):1748-54.
    • (2004) J Am Chem Soc. , vol.126 , Issue.6 , pp. 1748-1754
    • Fa, M.1    Radeghieri, A.2    Henry, A.A.3    Romesberg, F.E.4
  • 112
    • 33845658622 scopus 로고    scopus 로고
    • Anti-VEGF aptamer (pegaptanib) therapy for ocular vascular diseases
    • Ng EW, Adamis AP. Anti-VEGF aptamer (pegaptanib) therapy for ocular vascular diseases. Ann N Y Acad Sci. 2006;1082:151-71.
    • (2006) Ann N Y Acad Sci. , vol.1082 , pp. 151-171
    • Ng, E.W.1    Adamis, A.P.2
  • 113
    • 50449105530 scopus 로고    scopus 로고
    • SELEX with modified nucleotides
    • Keefe AD, Cload ST. SELEX with modified nucleotides. Curr Opin Chem Biol. 2008;12(4):448-56.
    • (2008) Curr Opin Chem Biol. , vol.12 , Issue.4 , pp. 448-456
    • Keefe, A.D.1    Cload, S.T.2
  • 116
    • 84888342497 scopus 로고    scopus 로고
    • Aptamer-based therapeutics: New approaches to combat human viral diseases
    • Shum KT, Zhou J, Rossi JJ. Aptamer-based therapeutics: new approaches to combat human viral diseases. Pharmaceuticals (Basel). 2013;6(12):1507-42.
    • (2013) Pharmaceuticals (Basel). , vol.6 , Issue.12 , pp. 1507-1542
    • Shum, K.T.1    Zhou, J.2    Rossi, J.J.3
  • 117
    • 0030582678 scopus 로고    scopus 로고
    • Bent pseudoknots and novel RNA inhibitors of type 1 human immunodeficiency virus (HIV-1) reverse transcriptase
    • Burke DH, Scates L, Andrews K, Gold L. Bent pseudoknots and novel RNA inhibitors of type 1 human immunodeficiency virus (HIV-1) reverse transcriptase. J Mol Biol. 1996; 264(4):650-66.
    • (1996) J Mol Biol. , vol.264 , Issue.4 , pp. 650-666
    • Burke, D.H.1    Scates, L.2    Andrews, K.3    Gold, L.4
  • 118
    • 0037106622 scopus 로고    scopus 로고
    • Endogenous expression of a high-affinity pseudoknot RNA aptamer suppresses replication of HIV-1
    • Chaloin L, Lehmann MJ, Sczakiel G, Restle T. Endogenous expression of a high-affinity pseudoknot RNA aptamer suppresses replication of HIV-1. Nucleic Acids Res. 2002; 30(18):4001-8.
    • (2002) Nucleic Acids Res. , vol.30 , Issue.18 , pp. 4001-4008
    • Chaloin, L.1    Lehmann, M.J.2    Sczakiel, G.3    Restle, T.4
  • 119
    • 84873667430 scopus 로고    scopus 로고
    • High-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptase
    • Ditzler MA, Lange MJ, Bose D, Bottoms CA, Virkler KF, Sawyer AW, et al. High-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptase. Nucleic Acids Res. 2013;41(3):1873-84.
    • (2013) Nucleic Acids Res. , vol.41 , Issue.3 , pp. 1873-1884
    • Ditzler, M.A.1    Lange, M.J.2    Bose, D.3    Bottoms, C.A.4    Virkler, K.F.5    Sawyer, A.W.6
  • 120
    • 33748753169 scopus 로고    scopus 로고
    • Differential susceptibility of HIV-1 reverse transcriptase to inhibition by RNA aptamers in enzymatic reactions monitoring specific steps during genome replication
    • Held DM, Kissel JD, Saran D, Michalowski D, Burke DH. Differential susceptibility of HIV-1 reverse transcriptase to inhibition by RNA aptamers in enzymatic reactions monitoring specific steps during genome replication. J Biol Chem. 2006;281(35):25712-22.
    • (2006) J Biol Chem. , vol.281 , Issue.35 , pp. 25712-25722
    • Held, D.M.1    Kissel, J.D.2    Saran, D.3    Michalowski, D.4    Burke, D.H.5
  • 121
    • 0036284226 scopus 로고    scopus 로고
    • Potent inhibition of human immunodeficiency virus type 1 replication by template analog reverse transcriptase inhibitors derived by SELEX (systematic evolution of ligands by exponential enrichment)
    • Joshi P, Prasad VR. Potent inhibition of human immunodeficiency virus type 1 replication by template analog reverse transcriptase inhibitors derived by SELEX (systematic evolution of ligands by exponential enrichment). J Virol. 2002;76(13):6545-57.
    • (2002) J Virol. , vol.76 , Issue.13 , pp. 6545-6557
    • Joshi, P.1    Prasad, V.R.2
  • 122
    • 0034674431 scopus 로고    scopus 로고
    • HIV-1 reverse transcriptase-pseudoknot RNA aptamer interaction has a binding affinity in the low picomolar range coupled with high specificity
    • Kensch O, Connolly BA, Steinhoff HJ, McGregor A, Goody RS, Restle T. HIV-1 reverse transcriptase-pseudoknot RNA aptamer interaction has a binding affinity in the low picomolar range coupled with high specificity. J Biol Chem. 2000;275(24):18271-8.
    • (2000) J Biol Chem. , vol.275 , Issue.24 , pp. 18271-18278
    • Kensch, O.1    Connolly, B.A.2    Steinhoff, H.J.3    McGregor, A.4    Goody, R.S.5    Restle, T.6
  • 123
    • 84870619242 scopus 로고    scopus 로고
    • Robust suppression of HIV replication by intracellularly expressed reverse transcriptase aptamers is independent of ribozyme processing
    • Lange MJ, Sharma TK, Whatley AS, Landon LA, Tempesta MA, Johnson MC, et al. Robust suppression of HIV replication by intracellularly expressed reverse transcriptase aptamers is independent of ribozyme processing. Mol Ther. 2012;20(12):2304-14.
    • (2012) Mol Ther. , vol.20 , Issue.12 , pp. 2304-2314
    • Lange, M.J.1    Sharma, T.K.2    Whatley, A.S.3    Landon, L.A.4    Tempesta, M.A.5    Johnson, M.C.6
  • 125
    • 0026651981 scopus 로고
    • RNA pseudoknots that inhibit human immunodeficiency virus type 1 reverse transcriptase
    • Tuerk C, MacDougal S, Gold L. RNA pseudoknots that inhibit human immunodeficiency virus type 1 reverse transcriptase. Proc Natl Acad Sci U S A. 1992;89(15):6988-92.
    • (1992) Proc Natl Acad Sci U S A. , vol.89 , Issue.15 , pp. 6988-6992
    • Tuerk, C.1    McDougal, S.2    Gold, L.3
  • 127
    • 18844454815 scopus 로고    scopus 로고
    • DNA aptamers as potential anti-HIV agents
    • Chou SH, Chin KH, Wang AH. DNA aptamers as potential anti-HIV agents. Trends Biochem Sci. 2005;30(5):231-4.
    • (2005) Trends Biochem Sci. , vol.30 , Issue.5 , pp. 231-234
    • Chou, S.H.1    Chin, K.H.2    Wang, A.H.3
  • 129
    • 14144254793 scopus 로고    scopus 로고
    • An interlocked dimeric parallel- stranded DNA quadruplex: A potent inhibitor of HIV-1 integrase
    • Phan AT, Kuryavyi V, Ma JB, Faure A, Andreola ML, Patel DJ. An interlocked dimeric parallel- stranded DNA quadruplex: a potent inhibitor of HIV-1 integrase. Proc Natl Acad Sci U S A. 2005;102(3):634-9.
    • (2005) Proc Natl Acad Sci U S A. , vol.102 , Issue.3 , pp. 634-639
    • Phan, A.T.1    Kuryavyi, V.2    Ma, J.B.3    Faure, A.4    Andreola, M.L.5    Patel, D.J.6
  • 130
    • 84859336905 scopus 로고    scopus 로고
    • Molecular dynamics of HIV1-integrase in complex with 93del-a structural perspective on the mechanism of inhibition
    • Sgobba M, Olubiyi O, Ke S, Haider S. Molecular dynamics of HIV1-integrase in complex with 93del-a structural perspective on the mechanism of inhibition. J Biomol Struct Dyn. 2012;29(5):863-77.
    • (2012) J Biomol Struct Dyn. , vol.29 , Issue.5 , pp. 863-877
    • Sgobba, M.1    Olubiyi, O.2    Ke, S.3    Haider, S.4
  • 131
    • 79959426343 scopus 로고    scopus 로고
    • The guanine-quadruplex aptamer 93del inhibits HIV-1 replication ex vivo by interfering with viral entry, reverse transcription and integration
    • Faure-Perraud A, Metifiot M, Reigadas S, Recordon-Pinson P, Parissi V, Ventura M, et al. The guanine-quadruplex aptamer 93del inhibits HIV-1 replication ex vivo by interfering with viral entry, reverse transcription and integration. Antivir Ther. 2011;16(3):383-94.
    • (2011) Antivir Ther. , vol.16 , Issue.3 , pp. 383-394
    • Faure-Perraud, A.1    Metifiot, M.2    Reigadas, S.3    Recordon-Pinson, P.4    Parissi, V.5    Ventura, M.6
  • 132
    • 0032567432 scopus 로고    scopus 로고
    • Structure-activity of tetrad-forming oligonucleotides as a potent anti-HIV therapeutic drug
    • Jing N, Hogan ME. Structure-activity of tetrad-forming oligonucleotides as a potent anti-HIV therapeutic drug. J Biol Chem. 1998;273(52):34992-9.
    • (1998) J Biol Chem. , vol.273 , Issue.52 , pp. 34992-34999
    • Jing, N.1    Hogan, M.E.2
  • 133
    • 0029964978 scopus 로고    scopus 로고
    • Inhibition of the human immunodeficiency virus type 1 integrase by guanosine quartet structures
    • Mazumder A, Neamati N, Ojwang JO, Sunder S, Rando RF, Pommier Y. Inhibition of the human immunodeficiency virus type 1 integrase by guanosine quartet structures. Biochemistry. 1996;35(43):13762-71.
    • (1996) Biochemistry. , vol.35 , Issue.43 , pp. 13762-13771
    • Mazumder, A.1    Neamati, N.2    Ojwang, J.O.3    Sunder, S.4    Rando, R.F.5    Pommier, Y.6
  • 134
    • 0028961595 scopus 로고
    • Suppression of human immunodeficiency virus type 1 activity in vitro by oligonucleotides which form intramolecular tetrads
    • Rando RF, Ojwang J, Elbaggari A, Reyes GR, Tinder R, McGrath MS, et al. Suppression of human immunodeficiency virus type 1 activity in vitro by oligonucleotides which form intramolecular tetrads. J Biol Chem. 1995;270(4):1754-60.
    • (1995) J Biol Chem. , vol.270 , Issue.4 , pp. 1754-1760
    • Rando, R.F.1    Ojwang, J.2    Elbaggari, A.3    Reyes, G.R.4    Tinder, R.5    McGrath, M.S.6
  • 135
    • 84874631908 scopus 로고    scopus 로고
    • d(GGGT) 4 and r(GGGU) 4 are both HIV-1 inhibitors and interleukin-6 receptor aptamers
    • Magbanua E, Zivkovic T, Hansen B, Beschorner N, Meyer C, Lorenzen I, et al. d(GGGT) 4 and r(GGGU) 4 are both HIV-1 inhibitors and interleukin-6 receptor aptamers. RNA Biol. 2013;10(2):216-27.
    • (2013) RNA Biol. , vol.10 , Issue.2 , pp. 216-227
    • Magbanua, E.1    Zivkovic, T.2    Hansen, B.3    Beschorner, N.4    Meyer, C.5    Lorenzen, I.6
  • 136
    • 0036299027 scopus 로고    scopus 로고
    • Structural characterization of a 2′FRNA aptamer that binds a HIV-1 SU glycoprotein, gp120
    • Sayer N, Ibrahim J, Turner K, Tahiri-Alaoui A, James W. Structural characterization of a 2′FRNA aptamer that binds a HIV-1 SU glycoprotein, gp120. Biochem Biophys Res Commun. 2002;293(3):924-31.
    • (2002) Biochem Biophys Res Commun. , vol.293 , Issue.3 , pp. 924-931
    • Sayer, N.1    Ibrahim, J.2    Turner, K.3    Tahiri-Alaoui, A.4    James, W.5
  • 137
    • 0242409220 scopus 로고    scopus 로고
    • Neutralization of infectivity of diverse R5 clinical isolates of human immunodeficiency virus type 1 by gp120-binding 2'F-RNA aptamers
    • Khati M, Schuman M, Ibrahim J, Sattentau Q, Gordon S, James W. Neutralization of infectivity of diverse R5 clinical isolates of human immunodeficiency virus type 1 by gp120-binding 2'F-RNA aptamers. J Virol. 2003;77(23):12692-8.
    • (2003) J Virol. , vol.77 , Issue.23 , pp. 12692-12698
    • Khati, M.1    Schuman, M.2    Ibrahim, J.3    Sattentau, Q.4    Gordon, S.5    James, W.6
  • 138
    • 54049134705 scopus 로고    scopus 로고
    • An aptamer that neutralizes R5 strains of HIV-1 binds to core residues of gp120 in the CCR5 binding site
    • Cohen C, Forzan M, Sproat B, Pantophlet R, McGowan I, Burton D, et al. An aptamer that neutralizes R5 strains of HIV-1 binds to core residues of gp120 in the CCR5 binding site. Virology. 2008;381(1):46-54.
    • (2008) Virology. , vol.381 , Issue.1 , pp. 46-54
    • Cohen, C.1    Forzan, M.2    Sproat, B.3    Pantophlet, R.4    McGowan, I.5    Burton, D.6
  • 139
    • 21844443592 scopus 로고    scopus 로고
    • Structural characterization of an anti-gp120 RNA aptamer that neutralizes R5 strains of HIV-1
    • Dey AK, Griffiths C, Lea SM, James W. Structural characterization of an anti-gp120 RNA aptamer that neutralizes R5 strains of HIV-1. RNA. 2005;11(6):873-84.
    • (2005) RNA. , vol.11 , Issue.6 , pp. 873-884
    • Dey, A.K.1    Griffiths, C.2    Lea, S.M.3    James, W.4
  • 140
    • 27144483814 scopus 로고    scopus 로고
    • An aptamer that neutralizes R5 strains of human immunodeficiency virus type 1 blocks gp120-CCR5 interaction
    • Dey AK, Khati M, Tang M, Wyatt R, Lea SM, James W. An aptamer that neutralizes R5 strains of human immunodeficiency virus type 1 blocks gp120-CCR5 interaction. J Virol. 2005;79(21):13806-10.
    • (2005) J Virol. , vol.79 , Issue.21 , pp. 13806-13810
    • Dey, A.K.1    Khati, M.2    Tang, M.3    Wyatt, R.4    Lea, S.M.5    James, W.6
  • 141
    • 77954576691 scopus 로고    scopus 로고
    • A modeled structure of an aptamer-gp120 complex provides insight into the mechanism of HIV-1 neutralization
    • Joubert MK, Kinsley N, Capovilla A, Sewell BT, Jaffer MA, Khati M. A modeled structure of an aptamer-gp120 complex provides insight into the mechanism of HIV-1 neutralization. Biochemistry. 2010;49(28):5880-90.
    • (2010) Biochemistry. , vol.49 , Issue.28 , pp. 5880-5890
    • Joubert, M.K.1    Kinsley, N.2    Capovilla, A.3    Sewell, B.T.4    Jaffer, M.A.5    Khati, M.6
  • 142
    • 84861309127 scopus 로고    scopus 로고
    • UCLA1, a synthetic derivative of a gp120 RNA aptamer, inhibits entry of human immunodeficiency virus type 1 subtype C
    • Mufhandu HT, Gray ES, Madiga MC, Tumba N, Alexandre KB, Khoza T, et al. UCLA1, a synthetic derivative of a gp120 RNA aptamer, inhibits entry of human immunodeficiency virus type 1 subtype C. J Virol. 2012;86(9):4989-99.
    • (2012) J Virol. , vol.86 , Issue.9 , pp. 4989-4999
    • Mufhandu, H.T.1    Gray, E.S.2    Madiga, M.C.3    Tumba, N.4    Alexandre, K.B.5    Khoza, T.6
  • 143
    • 66249129385 scopus 로고    scopus 로고
    • Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells
    • Zhou J, Swiderski P, Li H, Zhang J, Neff CP, Akkina R, et al. Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells. Nucleic Acids Res. 2009;37(9):3094-109.
    • (2009) Nucleic Acids Res. , vol.37 , Issue.9 , pp. 3094-3109
    • Zhou, J.1    Swiderski, P.2    Li, H.3    Zhang, J.4    Neff, C.P.5    Akkina, R.6
  • 144
    • 48349105059 scopus 로고    scopus 로고
    • Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy
    • Zhou J, Li H, Li S, Zaia J, Rossi JJ. Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy. Mol Ther. 2008;16(8):1481-9.
    • (2008) Mol Ther. , vol.16 , Issue.8 , pp. 1481-1489
    • Zhou, J.1    Li, H.2    Li, S.3    Zaia, J.4    Rossi, J.J.5
  • 146
    • 78751667739 scopus 로고    scopus 로고
    • An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice
    • Neff CP, Zhou J, Remling L, Kuruvilla J, Zhang J, Li H, et al. An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice. Sci Transl Med. 2011;3(66):66ra6.
    • (2011) Sci Transl Med. , vol.3 , Issue.66
    • Neff, C.P.1    Zhou, J.2    Remling, L.3    Kuruvilla, J.4    Zhang, J.5    Li, H.6
  • 147
    • 84871919249 scopus 로고    scopus 로고
    • Functional in vivo delivery of multiplexed anti-HIV-1 siRNAs via a chemically synthesized aptamer with a sticky bridge
    • Zhou J, Neff CP, Swiderski P, Li H, Smith DD, Aboellail T, et al. Functional in vivo delivery of multiplexed anti-HIV-1 siRNAs via a chemically synthesized aptamer with a sticky bridge. Mol Ther. 2013;21(1):192-200.
    • (2013) Mol Ther. , vol.21 , Issue.1 , pp. 192-200
    • Zhou, J.1    Neff, C.P.2    Swiderski, P.3    Li, H.4    Smith, D.D.5    Aboellail, T.6
  • 148
    • 79958716788 scopus 로고    scopus 로고
    • Dual functional RNA nanoparticles containing phi29 motor pRNA and anti-gp120 aptamer for cell-type specific delivery and HIV-1 inhibition
    • Zhou J, Shu Y, Guo P, Smith DD, Rossi JJ. Dual functional RNA nanoparticles containing phi29 motor pRNA and anti-gp120 aptamer for cell-type specific delivery and HIV-1 inhibition. Methods. 2011;54(2):284-94.
    • (2011) Methods. , vol.54 , Issue.2 , pp. 284-294
    • Zhou, J.1    Shu, Y.2    Guo, P.3    Smith, D.D.4    Rossi, J.J.5
  • 149
    • 79957905425 scopus 로고    scopus 로고
    • Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamersiRNA chimeras
    • Wheeler LA, Trifonova R, Vrbanac V, Basar E, McKernan S, Xu Z, et al. Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamersiRNA chimeras. J Clin Invest. 2011;121(6):2401-12.
    • (2011) J Clin Invest. , vol.121 , Issue.6 , pp. 2401-2412
    • Wheeler, L.A.1    Trifonova, R.2    Vrbanac, V.3    Basar, E.4    McKernan, S.5    Xu, Z.6
  • 150
    • 84879691173 scopus 로고    scopus 로고
    • Durable knockdown and protection from HIV transmission in humanized mice treated with gelformulated CD4 aptamer-siRNA chimeras
    • Wheeler LA, Vrbanac V, Trifonova R, Brehm MA, Gilboa-Geffen A, Tanno S, et al. Durable knockdown and protection from HIV transmission in humanized mice treated with gelformulated CD4 aptamer-siRNA chimeras. Mol Ther. 2013;21(7):1378-89.
    • (2013) Mol Ther. , vol.21 , Issue.7 , pp. 1378-1389
    • Wheeler, L.A.1    Vrbanac, V.2    Trifonova, R.3    Brehm, M.A.4    Gilboa-Geffen, A.5    Tanno, S.6
  • 151
    • 84867997347 scopus 로고    scopus 로고
    • Inhibition of HIV-1 protease expression in T cells owing to DNA aptamer-mediated specific delivery of siRNA
    • Zhu Q, Shibata T, Kabashima T, Kai M. Inhibition of HIV-1 protease expression in T cells owing to DNA aptamer-mediated specific delivery of siRNA. Eur J Med Chem. 2012;56:396-9.
    • (2012) Eur J Med Chem. , vol.56 , pp. 396-399
    • Zhu, Q.1    Shibata, T.2    Kabashima, T.3    Kai, M.4
  • 152
    • 0034482696 scopus 로고    scopus 로고
    • Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates
    • Kwong PD, Wyatt R, Majeed S, Robinson J, Sweet RW, Sodroski J, et al. Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates. Structure. 2000;8(12):1329-39.
    • (2000) Structure. , vol.8 , Issue.12 , pp. 1329-1339
    • Kwong, P.D.1    Wyatt, R.2    Majeed, S.3    Robinson, J.4    Sweet, R.W.5    Sodroski, J.6
  • 154
    • 80054730117 scopus 로고    scopus 로고
    • Rational truncation of an RNA aptamer to prostate-specific membrane antigen using computational structural modeling
    • Rockey WM, Hernandez FJ, Huang SY, Cao S, Howell CA, Thomas GS, et al. Rational truncation of an RNA aptamer to prostate-specific membrane antigen using computational structural modeling. Nucleic Acids Ther. 2011;21(5):299-314.
    • (2011) Nucleic Acids Ther. , vol.21 , Issue.5 , pp. 299-314
    • Rockey, W.M.1    Hernandez, F.J.2    Huang, S.Y.3    Cao, S.4    Howell, C.A.5    Thomas, G.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.