-
1
-
-
0030582678
-
Bent pseudoknots and novel RNA inhibitors of type 1 human immunodeficiency virus (HIV-1) reverse transcriptase
-
Burke, DH, Scates, L, Andrews, K and Gold, L (1996). Bent pseudoknots and novel RNA inhibitors of type 1 human immunodeficiency virus (HIV-1) reverse transcriptase. J Mol Biol 264: 650-666.
-
(1996)
J Mol Biol
, vol.264
, pp. 650-666
-
-
Burke, D.H.1
Scates, L.2
Andrews, K.3
Gold, L.4
-
2
-
-
0026651981
-
RNA pseudoknots that inhibit human immunodeficiency virus type 1 reverse transcriptase
-
Tuerk, C, MacDougal, S and Gold, L (1992). RNA pseudoknots that inhibit human immunodeficiency virus type 1 reverse transcriptase. Proc Natl Acad Sci USA 89: 6988-6992.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 6988-6992
-
-
Tuerk, C.1
MacDougal, S.2
Gold, L.3
-
3
-
-
36749061427
-
Antiviral aptamers
-
Gopinath, SC (2007). Antiviral aptamers. Arch Virol 152: 2137-2157.
-
(2007)
Arch Virol
, vol.152
, pp. 2137-2157
-
-
Gopinath, S.C.1
-
4
-
-
32844463163
-
HIV-1 inactivation by nucleic acid aptamers
-
Held, DM, Kissel, JD, Patterson, JT, Nickens, DG and Burke, DH (2006). HIV-1 inactivation by nucleic acid aptamers. Front Biosci 11: 89-112.
-
(2006)
Front Biosci
, vol.11
, pp. 89-112
-
-
Held, D.M.1
Kissel, J.D.2
Patterson, J.T.3
Nickens, D.G.4
Burke, D.H.5
-
5
-
-
84856389509
-
RNA-based therapeutics: Current progress and future prospects
-
Burnett, JC and Rossi, JJ. (2012). RNA-based therapeutics: current progress and future prospects. Chemistry & Biology 19, 60-71.
-
(2012)
Chemistry & Biology
, vol.19
, pp. 60-71
-
-
Burnett, J.C.1
Rossi, J.J.2
-
6
-
-
17644395235
-
Aptamers directed to HIV-1 reverse transcriptase display greater efficacy over small hairpin RNAs targeted to viral RNA in blocking HIV-1 replication
-
Joshi, PJ, North, TW and Prasad, VR (2005). Aptamers directed to HIV-1 reverse transcriptase display greater efficacy over small hairpin RNAs targeted to viral RNA in blocking HIV-1 replication. Mol Ther 11: 677-686.
-
(2005)
Mol Ther
, vol.11
, pp. 677-686
-
-
Joshi, P.J.1
North, T.W.2
Prasad, V.R.3
-
7
-
-
78751667739
-
An aptamersiRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice
-
Neff, CP, Zhou, J, Remling, L, Kuruvilla, J, Zhang, J, Li, H et al. (2011). An aptamersiRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice. Sci Transl Med 3: 66ra6.
-
(2011)
Sci Transl Med
, vol.3
-
-
Neff, C.P.1
Zhou, J.2
Remling, L.3
Kuruvilla, J.4
Zhang, J.5
Li, H.6
-
8
-
-
0037106622
-
Endogenous expression of a high-affinity pseudoknot RNA aptamer suppresses replication of HIV-1
-
Chaloin, L, Lehmann, MJ, Sczakiel, G and Restle, T (2002). Endogenous expression of a high-affinity pseudoknot RNA aptamer suppresses replication of HIV-1.Nucleic Acids Res 30: 4001-4008.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 4001-4008
-
-
Chaloin, L.1
Lehmann, M.J.2
Sczakiel, G.3
Restle, T.4
-
9
-
-
33947623718
-
Endogenous expression of an anti-TAR aptamer reduces HIV-1 replication
-
.Kolb, G, Reigadas, S, Castanotto, D, Faure, A, Ventura, M, Rossi, JJ et al. (2006). Endogenous expression of an anti-TAR aptamer reduces HIV-1 replication. RNA Biol 3: 150-156.
-
(2006)
RNA Biol
, vol.3
, pp. 150-156
-
-
Kolb, G.1
Reigadas, S.2
Castanotto, D.3
Faure, A.4
Ventura, M.5
Rossi, J.J.6
-
10
-
-
0036284226
-
Potent inhibition of human immunodeficiency virus type 1 replication by template analog reverse transcriptase inhibitors derived by SELEX (systematic evolution of ligands by exponential enrichment
-
.Joshi, P and Prasad, VR (2002). Potent inhibition of human immunodeficiency virus type 1 replication by template analog reverse transcriptase inhibitors derived by SELEX (systematic evolution of ligands by exponential enrichment). J Virol 76: 6545-6557.
-
(2002)
J Virol
, vol.76
, pp. 6545-6557
-
-
Joshi, P.1
Prasad, V.R.2
-
11
-
-
78650066594
-
RNA aptamers directed to human immunodeficiency virus type 1 Gag polyprotein bind to the matrix and nucleocapsid domains and inhibit virus production
-
.Ramalingam, D, Duclair, S, Datta, SA, Ellington, A, Rein, A and Prasad, VR (2011). RNA aptamers directed to human immunodeficiency virus type 1 Gag polyprotein bind to the matrix and nucleocapsid domains and inhibit virus production. J Virol 85: 305-314.
-
(2011)
J Virol
, vol.85
, pp. 305-314
-
-
Ramalingam, D.1
Duclair, S.2
Datta, S.A.3
Ellington, A.4
Rein, A.5
Prasad, V.R.6
-
12
-
-
70349308212
-
An adenovirus-delivered peptide aptamer C1-1 targeting the core protein of hepatitis B virus inhibits viral DNA replication and production in vitro and in vivo
-
.Zhang, W, Ke, W, Wu, SS Gan, L, Zhou, R Sun, CY et al. An adenovirus-delivered peptide aptamer C1-1 targeting the core protein of hepatitis B virus inhibits viral DNA replication and production in vitro and in vivo. Peptides 30, 1816-1821 (2009).
-
(2009)
Peptides
, vol.30
, pp. 1816-1821
-
-
Zhang, W.1
Ke, W.2
Wu Gan, S.S.L.3
Zhou Sun, R.C.Y.4
-
13
-
-
81355142732
-
A SELEX-screened aptamer of human hepatitis B virus RNA encapsidation signal suppresses viral replication
-
Feng, H, Beck, J, Nassal, M and Hu, KH. A SELEX-screened aptamer of human hepatitis B virus RNA encapsidation signal suppresses viral replication. PLoS One 6, e27862 (2011).
-
(2011)
PLoS One
, vol.6
-
-
Feng, H.1
Beck, J.2
Nassal, M.3
Hu, K.H.4
-
14
-
-
70350306538
-
Inhibition of human cytomegalovirus replication via peptide aptamers directed against the nonconventional nuclear localization signal of the essential viral replication factor pUL84
-
.Kaiser, N, Lischka, P, Wagenknecht, N and Stamminger, T (2009). Inhibition of human cytomegalovirus replication via peptide aptamers directed against the nonconventional nuclear localization signal of the essential viral replication factor pUL84. J Virol 83: 11902-11913.
-
(2009)
J Virol
, vol.83
, pp. 11902-11913
-
-
Kaiser, N.1
Lischka, P.2
Wagenknecht, N.3
Stamminger, T.4
-
15
-
-
36048973544
-
Designing and analysis of a potent bi-functional aptamers that inhibit protease and helicase activities of HCV NS3
-
Umehara, T, Fukuda, K, Nishikawa, F, Sekiya, S, Kohara, M, Hasegawa, T et al. (2004). Designing and analysis of a potent bi-functional aptamers that inhibit protease and helicase activities of HCV NS3. Nucleic Acids Symp Ser (Oxf) : 195-196.
-
(2004)
Nucleic Acids Symp ser (Oxf)
, pp. 195-196
-
-
Umehara, T.1
Fukuda, K.2
Nishikawa, F.3
Sekiya, S.4
Kohara, M.5
Hasegawa, T.6
-
16
-
-
67849119062
-
Inhibition of hepatitis C virus replication and internal ribosome entry site-dependent translation by an RNA molecule
-
.Romero-Lopez, C, Diaz-Gonzalez, R, Barroso-delJesus, A and Berzal-Herranz, A (2009). Inhibition of hepatitis C virus replication and internal ribosome entry site-dependent translation by an RNA molecule. J Gen Virol 90(Pt 7): 1659-1669.
-
(2009)
J Gen Virol
, vol.90
, Issue.PART 7
, pp. 1659-1669
-
-
Romero-Lopez, C.1
Diaz-Gonzalez, R.2
Barroso-Deljesus, A.3
Berzal-Herranz, A.4
-
17
-
-
33746344690
-
Peptide aptamer-mediated inhibition of target proteins by sequestration into aggresomes
-
.Tomai, E, Butz, K, Lohrey, C, von Weizsacker, F, Zentgraf, H and Hoppe-Seyler, F (2006). Peptide aptamer-mediated inhibition of target proteins by sequestration into aggresomes. J Biol Chem 281: 21345-21352.
-
(2006)
J Biol Chem
, vol.281
, pp. 21345-21352
-
-
Tomai, E.1
Butz, K.2
Lohrey, C.3
Von Weizsacker, F.4
Zentgraf, H.5
Hoppe-Seyler, F.6
-
18
-
-
37649011633
-
Potent inhibition of human influenza H5N1 virus by oligonucleotides derived by SELEX
-
.Cheng, C, Dong, J, Yao, L, Chen, A, Jia, R, Huan, L et al. (2008). Potent inhibition of human influenza H5N1 virus by oligonucleotides derived by SELEX. Biochem Biophys Res Commun 366: 670-674.
-
(2008)
Biochem Biophys Res Commun
, vol.366
, pp. 670-674
-
-
Cheng, C.1
Dong, J.2
Yao, L.3
Chen, A.4
Jia, R.5
Huan, L.6
-
20
-
-
0346882677
-
Anti-HIV inhibitors based on nucleic acids: Emergence of aptamers as potent antivirals
-
.Joshi, PJ, Fisher, TS and Prasad, VR (2003). Anti-HIV inhibitors based on nucleic acids: emergence of aptamers as potent antivirals. Curr Drug Targets Infect Disord 3: 383-400.
-
(2003)
Curr Drug Targets Infect Disord
, vol.3
, pp. 383-400
-
-
Joshi, P.J.1
Fisher, T.S.2
Prasad, V.R.3
-
21
-
-
33750991861
-
The potential of oligonucleotides for therapeutic applications
-
.Fichou, Y and Ferec, C (2006). The potential of oligonucleotides for therapeutic applications. Trends Biotechnol 24: 563-570.
-
(2006)
Trends Biotechnol
, vol.24
, pp. 563-570
-
-
Fichou, Y.1
Ferec, C.2
-
22
-
-
57149086439
-
Aptamers that recognize drug-resistant HIV-1 reverse transcriptase
-
.Li, N, Wang, Y, Pothukuchy, A, Syrett, A, Husain, N, Gopalakrisha, S et al. (2008). Aptamers that recognize drug-resistant HIV-1 reverse transcriptase. Nucleic Acids Res 36: 6739-6751.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 6739-6751
-
-
Li, N.1
Wang, Y.2
Pothukuchy, A.3
Syrett, A.4
Husain, N.5
Gopalakrisha, S.6
-
23
-
-
80054055875
-
Broad-spectrum aptamer inhibitors of HIV reverse transcriptase closely mimic natural substrates
-
.Ditzler, MA, Bose, D, Shkriabai, N, Marchand, B, Sarafianos, SG, Kvaratskhelia, M et al. (2011). Broad-spectrum aptamer inhibitors of HIV reverse transcriptase closely mimic natural substrates. Nucleic Acids Res 39: 8237-8247.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 8237-8247
-
-
Ditzler, M.A.1
Bose, D.2
Shkriabai, N.3
Marchand, B.4
Sarafianos, S.G.5
Kvaratskhelia, M.6
-
24
-
-
34248380089
-
Crossclade inhibition of recombinant human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus SIVcpz reverse transcriptases by RNA pseudoknot aptamers
-
.Held, DM, Kissel, JD, Thacker, SJ, Michalowski, D, Saran, D, Ji, J et al. (2007). Crossclade inhibition of recombinant human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus SIVcpz reverse transcriptases by RNA pseudoknot aptamers. J Virol 81: 5375-5384.
-
(2007)
J Virol
, vol.81
, pp. 5375-5384
-
-
Held, D.M.1
Kissel, J.D.2
Thacker, S.J.3
Michalowski, D.4
Saran, D.5
Ji, J.6
-
25
-
-
33748753169
-
Differential susceptibility of HIV-1 reverse transcriptase to inhibition by RNA aptamers in enzymatic reactions monitoring specific steps during genome replication
-
.Held, DM, Kissel, JD, Saran, D, Michalowski, D and Burke, DH (2006). Differential susceptibility of HIV-1 reverse transcriptase to inhibition by RNA aptamers in enzymatic reactions monitoring specific steps during genome replication. J Biol Chem 281: 25712-25722.
-
(2006)
J Biol Chem
, vol.281
, pp. 25712-25722
-
-
Held, D.M.1
Kissel, J.D.2
Saran, D.3
Michalowski, D.4
Burke, D.H.5
-
26
-
-
34249864559
-
Single-stranded DNA aptamer RT1t49 inhibits RT polymerase and RNase H functions of HIV type 1, HIV type 2, and SIVCPZ RTs
-
Kissel, JD, Held, DM, Hardy, RW and Burke, DH (2007). Single-stranded DNA aptamer RT1t49 inhibits RT polymerase and RNase H functions of HIV type 1, HIV type 2, and SIVCPZ RTs. AIDS Res Hum Retroviruses 23: 699-708.
-
(2007)
AIDS Res Hum Retroviruses
, vol.23
, pp. 699-708
-
-
Kissel, J.D.1
Held, D.M.2
Hardy, R.W.3
Burke, D.H.4
-
27
-
-
38549129316
-
Instability of retroviral vectors with HIV-1-specific RT aptamers due to cryptic splice sites in the U6 promoter
-
Braun, SE, Shi, X, Qiu, G, Wong, FE, Joshi, PJ, Prasad, VR et al. (2007). Instability of retroviral vectors with HIV-1-specific RT aptamers due to cryptic splice sites in the U6 promoter. AIDS Res Ther 4: 24.
-
(2007)
AIDS Res Ther
, vol.4
, pp. 24
-
-
Braun, S.E.1
Shi, X.2
Qiu, G.3
Wong, F.E.4
Joshi, P.J.5
Prasad, V.R.6
-
28
-
-
0031878312
-
Triple ribozyme-mediated down-regulation of the retinoblastoma gene
-
Benedict, CM, Pan, W, Loy, SE and Clawson, GA (1998). Triple ribozyme-mediated down-regulation of the retinoblastoma gene. Carcinogenesis 19: 1223-1230.
-
(1998)
Carcinogenesis
, vol.19
, pp. 1223-1230
-
-
Benedict, C.M.1
Pan, W.2
Loy, S.E.3
Clawson, G.A.4
-
29
-
-
20044374522
-
An in vitro model of hepatitis C virion production
-
Heller, T, Saito, S, Auerbach, J, Williams, T, Moreen, TR, Jazwinski, A et al. (2005). An in vitro model of hepatitis C virion production. Proc Natl Acad Sci USA 102: 2579-2583.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 2579-2583
-
-
Heller, T.1
Saito, S.2
Auerbach, J.3
Williams, T.4
Moreen, T.R.5
Jazwinski, A.6
-
30
-
-
33645836124
-
Development of an efficient cis-trans-cis ribozyme cassette to inactivate plant genes
-
Bussiere, F, Ledu, S, Girard, M, Heroux, M, Perreault, JP and Matton, DP (2003). Development of an efficient cis-trans-cis ribozyme cassette to inactivate plant genes. Plant Biotechnol J 1: 423-435.
-
(2003)
Plant Biotechnol J
, vol.1
, pp. 423-435
-
-
Bussiere, F.1
Ledu, S.2
Girard, M.3
Heroux, M.4
Perreault, J.P.5
Matton, D.P.6
-
31
-
-
0043009734
-
Sequence elements outside the hammerhead ribozyme catalytic core enable intracellular activity
-
Khvorova, A, Lescoute, A, Westhof, E and Jayasena, SD (2003). Sequence elements outside the hammerhead ribozyme catalytic core enable intracellular activity. Nat Struct Biol 10: 708-712.
-
(2003)
Nat Struct Biol
, vol.10
, pp. 708-712
-
-
Khvorova, A.1
Lescoute, A.2
Westhof, E.3
Jayasena, S.D.4
-
32
-
-
26444443117
-
Low-magnesium, trans-cleavage activity by type III, tertiary stabilized hammerhead ribozymes with stem 1 discontinuities
-
Burke, DH and Greathouse, ST (2005). Low-magnesium, trans-cleavage activity by type III, tertiary stabilized hammerhead ribozymes with stem 1 discontinuities. BMC Biochem 6: 14.
-
(2005)
BMC Biochem
, vol.6
, pp. 14
-
-
Burke, D.H.1
Greathouse, S.T.2
-
33
-
-
0142105383
-
Peripheral regions of natural hammerhead ribozymes greatly increase their self-cleavage activity
-
De la Pena, M, Gago, S and Flores, R. (2003). Peripheral regions of natural hammerhead ribozymes greatly increase their self-cleavage activity. EMBO J 22: 5561-5570.
-
(2003)
EMBO J
, vol.22
, pp. 5561-5570
-
-
De La Pena, M.1
Gago, S.2
Flores, R.3
-
34
-
-
1942453705
-
Ciscleavage affects hammerhead and hairpin ribozyme steady-state levels differently and has strong impact on trans-targeting efficiency
-
Andang, M, Maijgren-Steffensson, C, Hinkula, J and Ahrlund-Richter, L (2004). Ciscleavage affects hammerhead and hairpin ribozyme steady-state levels differently and has strong impact on trans-targeting efficiency. Oligonucleotides 14: 11-21.
-
(2004)
Oligonucleotides
, vol.14
, pp. 11-21
-
-
Andang, M.1
Maijgren-Steffensson, C.2
Hinkula, J.3
Ahrlund-Richter, L.4
-
35
-
-
9344265166
-
Artificial tertiary motifs stabilize trans-cleaving hammerhead ribozymes under conditions of submillimolar divalent ions and high temperatures
-
Saksmerprome, V, Roychowdhury-Saha, M, Jayasena, S, Khvorova, A and Burke, DH (2004). Artificial tertiary motifs stabilize trans-cleaving hammerhead ribozymes under conditions of submillimolar divalent ions and high temperatures. RNA 10: 1916-1924.
-
(2004)
RNA
, vol.10
, pp. 1916-1924
-
-
Saksmerprome, V.1
Roychowdhury-Saha, M.2
Jayasena, S.3
Khvorova, A.4
Burke, D.H.5
-
36
-
-
0141846926
-
Encapsidation and transduction of cellular genes by retroviruses
-
Muriaux, D and Rein, A (2003). Encapsidation and transduction of cellular genes by retroviruses. Front Biosci 8: d135-d142.
-
(2003)
Front Biosci
, vol.8
-
-
Muriaux, D.1
Rein, A.2
-
37
-
-
0036665592
-
Optimizing aptamer activity for gene therapy applications using expression cassette SELEX
-
Martell, RE, Nevins, JR and Sullenger, BA (2002). Optimizing aptamer activity for gene therapy applications using expression cassette SELEX. Mol Ther 6: 30-34.
-
(2002)
Mol Ther
, vol.6
, pp. 30-34
-
-
Martell, R.E.1
Nevins, J.R.2
Sullenger, B.A.3
-
38
-
-
0029044477
-
Improved accumulation and activity of ribozymes expressed from a tRNA-based RNA polymerase III promoter
-
Thompson, JD, Ayers, DF, Malmstrom, TA, McKenzie, TL, Ganousis, L, Chowrira, BM et al. (1995). Improved accumulation and activity of ribozymes expressed from a tRNA-based RNA polymerase III promoter. Nucleic Acids Res 23: 2259-2268.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 2259-2268
-
-
Thompson, J.D.1
Ayers, D.F.2
Malmstrom, T.A.3
McKenzie, T.L.4
Ganousis, L.5
Chowrira, B.M.6
-
39
-
-
78049296915
-
Nuclear export of mRNA
-
Stewart, M (2010). Nuclear export of mRNA. Trends Biochem Sci 35: 609-617.
-
(2010)
Trends Biochem Sci
, vol.35
, pp. 609-617
-
-
Stewart, M.1
-
40
-
-
0034076868
-
Nuclear RNA export pathways
-
Cullen, BR (2000). Nuclear RNA export pathways. Mol Cell Biol 20: 4181-4187.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4181-4187
-
-
Cullen, B.R.1
-
41
-
-
33750295885
-
Transfection of mammalian cells using linear polyethylenimine is a simple and effective means of producing recombinant adeno-associated virus vectors
-
Reed, SE, Staley, EM, Mayginnes, JP, Pintel, DJ and Tullis, GE (2006). Transfection of mammalian cells using linear polyethylenimine is a simple and effective means of producing recombinant adeno-associated virus vectors. J Virol Methods 138: 85-98.
-
(2006)
J Virol Methods
, vol.138
, pp. 85-98
-
-
Reed, S.E.1
Staley, E.M.2
Mayginnes, J.P.3
Pintel, D.J.4
Tullis, G.E.5
-
42
-
-
84870609632
-
RNA: A laboratory manual
-
Donald, C, Rio, GJH, Manuel Ares Jr. and Nilsen, TW. RNA: A Laboratory Manual. (John Inglis, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 2011).
-
John Inglis, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 2011
-
-
Donald, C.1
Gjh, R.2
Ares Jr., M.3
Nilsen, T.W.4
-
43
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl, MW. (2001). A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: e45.
-
(2001)
Nucleic Acids Res
, vol.29
-
-
Pfaffl, M.W.1
-
44
-
-
77956027418
-
Analyzing mRNA expression using single mRNA resolution fluorescent in situ hybridization
-
Zenklusen, D and Singer, RH (2010). Analyzing mRNA expression using single mRNA resolution fluorescent in situ hybridization. Meth Enzymol 470: 641-659.
-
(2010)
Meth Enzymol
, vol.470
, pp. 641-659
-
-
Zenklusen, D.1
Singer, R.H.2
-
45
-
-
0037301586
-
Localized expression of small RNA inhibitors in human cells
-
Paul, CP, Good, PD, Li, SX, Kleihauer, A, Rossi, JJ and Engelke, DR (2003). Localized expression of small RNA inhibitors in human cells. Mol Ther 7: 237-247.
-
(2003)
Mol Ther
, vol.7
, pp. 237-247
-
-
Paul, C.P.1
Good, P.D.2
Li, S.X.3
Kleihauer, A.4
Rossi, J.J.5
Engelke, D.R.6
|