-
1
-
-
0028123452
-
A specific orientation of RNA secondary structures is required for initiation of reverse transcription
-
Aiyar, A., Ge, Z. & Leis, J. (1994). A specific orientation of RNA secondary structures is required for initiation of reverse transcription. J. Virol. 68, 611-618.
-
(1994)
J. Virol.
, vol.68
, pp. 611-618
-
-
Aiyar, A.1
Ge, Z.2
Leis, J.3
-
2
-
-
0028932883
-
Structures of DNA and RNA polymerases and their interactions with nucleic acid substrates
-
Arnold, E., Ding, J., Hughes, S. H. & Hostomsky, Z. (1995). Structures of DNA and RNA polymerases and their interactions with nucleic acid substrates. Curr. Opin. Struct. Biol. 5, 27-38.
-
(1995)
Curr. Opin. Struct. Biol.
, vol.5
, pp. 27-38
-
-
Arnold, E.1
Ding, J.2
Hughes, S.H.3
Hostomsky, Z.4
-
3
-
-
0027488624
-
Isolation of new ribozymes from a large pool of random sequences
-
Bartel, D. P. & Szostak, J. W. (1993). Isolation of new ribozymes from a large pool of random sequences. Science, 261, 1411-1418.
-
(1993)
Science
, vol.261
, pp. 1411-1418
-
-
Bartel, D.P.1
Szostak, J.W.2
-
4
-
-
0028844440
-
Efficacy of constant infusion of A-77003, an inhibitor of the human immunodeficiency virus type 1 (HIV-1) protease, in limiting acute HIV-1 infection in vitro
-
Bilello, J. A., Bilello, P. A., Kort, J. J., Dudley, M. N., Leonard, J. & Drusano, G. L. (1995). Efficacy of constant infusion of A-77003, an inhibitor of the human immunodeficiency virus type 1 (HIV-1) protease, in limiting acute HIV-1 infection in vitro. Antiomicrob. Agents Chemother. 39, 2523-2527.
-
(1995)
Antiomicrob. Agents Chemother.
, vol.39
, pp. 2523-2527
-
-
Bilello, J.A.1
Bilello, P.A.2
Kort, J.J.3
Dudley, M.N.4
Leonard, J.5
Drusano, G.L.6
-
5
-
-
0027995790
-
Isolation of RNA aptamers for biological cofactors by in vitro selection
-
Burgstaller, P. & Famulok, M. (1994). Isolation of RNA aptamers for biological cofactors by in vitro selection. Angewandte Chemie-Int. Ed. English, 33, 1084-1087.
-
(1994)
Angewandte Chemie-Int. Ed. English
, vol.33
, pp. 1084-1087
-
-
Burgstaller, P.1
Famulok, M.2
-
6
-
-
0028065203
-
Selection of high-affinity RNA ligands to reverse transcriptases: Inhibition of cDNA synthesis and RNase H activity
-
Chen, H. & Gold, L. (1994). Selection of high-affinity RNA ligands to reverse transcriptases: inhibition of cDNA synthesis and RNase H activity. Biochemistry, 33, 8746-8756.
-
(1994)
Biochemistry
, vol.33
, pp. 8746-8756
-
-
Chen, H.1
Gold, L.2
-
7
-
-
0029945147
-
Inhibitory RNA ligands to feline immunodeficiency virus reverse transcriptase
-
Chen, H., McBroom, D. C., Zhu, Y.-Q., North, T. & Gold, L. (1996). Inhibitory RNA ligands to feline immunodeficiency virus reverse transcriptase. Biochemistry, 35, 6923-6930.
-
(1996)
Biochemistry
, vol.35
, pp. 6923-6930
-
-
Chen, H.1
McBroom, D.C.2
Zhu, Y.-Q.3
North, T.4
Gold, L.5
-
8
-
-
0028962374
-
Structural and functional studies of retroviral RNA pseudoknots involved in ribosomal frameshifting: Nucleotides at the junction of the two stems are important for efficient ribosomal frameshifting
-
Chen, X., Chamorro, M., Lee, S. I., Shen, L. X., Hinesm, J. V., Tinoco, I. J., Jr & Varmus, H. E. (1995). Structural and functional studies of retroviral RNA pseudoknots involved in ribosomal frameshifting: nucleotides at the junction of the two stems are important for efficient ribosomal frameshifting. EMBO J. 14, 842-852.
-
(1995)
EMBO J.
, vol.14
, pp. 842-852
-
-
Chen, X.1
Chamorro, M.2
Lee, S.I.3
Shen, L.X.4
Hinesm, J.V.5
Tinoco I.J., Jr.6
Varmus, H.E.7
-
9
-
-
0029075207
-
Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse non-nucleoside inhibitors
-
Ding, J., Das, K., Moereels, H., Koymans, L., Andries, K., Janssen, P. A., Hughes, S. H. & Arnold, E. (1995). Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse non-nucleoside inhibitors. Nature Struct. Biol. 2, 407-415.
-
(1995)
Nature Struct. Biol.
, vol.2
, pp. 407-415
-
-
Ding, J.1
Das, K.2
Moereels, H.3
Koymans, L.4
Andries, K.5
Janssen, P.A.6
Hughes, S.H.7
Arnold, E.8
-
10
-
-
0027328347
-
Protein-DNA complexes: The cost of recognition
-
Draper, D. E. (1993). Protein-DNA complexes: the cost of recognition. Proc. Natl Acad. Sci. USA, 90, 7429-7430.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 7429-7430
-
-
Draper, D.E.1
-
11
-
-
0028945841
-
HIV-1 reverse transcriptase-associated RNase H cleaves RNA/RNA in arrested complexes: Implications for the mechanism by which RNase H discriminates between RNA and RNA/DNA
-
Gotte, M., Fackler, S., Hermann, T., Perola, E., Cellai, L., Gross, H. J., Le Grice, S. F. & Heumann, H. (1995). HIV-1 reverse transcriptase-associated RNase H cleaves RNA/RNA in arrested complexes: implications for the mechanism by which RNase H discriminates between RNA and RNA/DNA. EMBO J. 14, 833-841.
-
(1995)
EMBO J.
, vol.14
, pp. 833-841
-
-
Gotte, M.1
Fackler, S.2
Hermann, T.3
Perola, E.4
Cellai, L.5
Gross, H.J.6
Le Grice, S.F.7
Heumann, H.8
-
12
-
-
0028960472
-
Comprehensive chemical modification interference and nucleotide substitution analysis of an RNA pseudoknot inhibitor to HIV-1 reverse transcriptase
-
Green, L., MacDougal-Waugh, S., Binkley, J. P., Hostomska, Z., Hostomsky, Z. & Tuerk, C. (1995). Comprehensive chemical modification interference and nucleotide substitution analysis of an RNA pseudoknot inhibitor to HIV-1 reverse transcriptase. J. Mol. Biol. 247, 60-68.
-
(1995)
J. Mol. Biol.
, vol.247
, pp. 60-68
-
-
Green, L.1
MacDougal-Waugh, S.2
Binkley, J.P.3
Hostomska, Z.4
Hostomsky, Z.5
Tuerk, C.6
-
13
-
-
0026325728
-
SELEXION -Systematic evolution of ligands by exponential enrichment with integrated optimization by non-linear analysis
-
Irvine, D., Tuerk, C. & Gold, L. (1991). SELEXION -Systematic evolution of ligands by exponential enrichment with integrated optimization by non-linear analysis. J. Mol. Biol. 222, 739-761.
-
(1991)
J. Mol. Biol.
, vol.222
, pp. 739-761
-
-
Irvine, D.1
Tuerk, C.2
Gold, L.3
-
14
-
-
0028936075
-
Initiation of reverse transcription of HIV-1: Secondary structure of the HIV-1 RNA/tRNA(3Lys) (template/primer)
-
Isel, C., Ehresmann, C., Keith, G., Ehresmann, B. & Marquet, R. (1995). Initiation of reverse transcription of HIV-1: secondary structure of the HIV-1 RNA/tRNA(3Lys) (template/primer). J. Mol. Biol. 247, 236-250.
-
(1995)
J. Mol. Biol.
, vol.247
, pp. 236-250
-
-
Isel, C.1
Ehresmann, C.2
Keith, G.3
Ehresmann, B.4
Marquet, R.5
-
15
-
-
0030048748
-
Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy
-
Iversen, A. K., Shafer, R. W., Wehrly, K., Winters, M. A., Mullins, J. I., Chesebro, B. & Merigan, T. C. (1996). Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy. J. Virol. 70, 1086-1090.
-
(1996)
J. Virol.
, vol.70
, pp. 1086-1090
-
-
Iversen, A.K.1
Shafer, R.W.2
Wehrly, K.3
Winters, M.A.4
Mullins, J.I.5
Chesebro, B.6
Merigan, T.C.7
-
16
-
-
0027318776
-
Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 Å resolution shows bent DNA
-
Jacobo-Molina, A., Ding, J., Nanni, R. G., Clark, A. D. J., Lu, X., Tantillo, C., Williams, R. L., Kamer, G., Ferris, A. L., Clark, P., Hizi, A., Hughes, S. H. & Arnold, E. (1993). Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 Å resolution shows bent DNA. Proc. Natl Acad. Sci. USA, 90, 6320-6324.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 6320-6324
-
-
Jacobo-Molina, A.1
Ding, J.2
Nanni, R.G.3
Clark, A.D.J.4
Lu, X.5
Tantillo, C.6
Williams, R.L.7
Kamer, G.8
Ferris, A.L.9
Clark, P.10
Hizi, A.11
Hughes, S.H.12
Arnold, E.13
-
17
-
-
0028774179
-
Comparison of three different crystal forms shows HIV-1 reverse transcriptase displays an internal swivel motion
-
Jager, J., Smerdon, S. J., Wang, J., Boisvert, D. C. & Steitz, T. A. (1994). Comparison of three different crystal forms shows HIV-1 reverse transcriptase displays an internal swivel motion. Structure, 2, 869-876.
-
(1994)
Structure
, vol.2
, pp. 869-876
-
-
Jager, J.1
Smerdon, S.J.2
Wang, J.3
Boisvert, D.C.4
Steitz, T.A.5
-
18
-
-
0030063081
-
Potent human immunodeficiency virus type 1 protease inhibitors that utilize noncoded D-amino acids as P2/P3 ligands
-
Jungheim, L. N., Shepherd, T. A., Baxter, A. J., Burgess, J., Hatch, S. D., Lubbehusen, P., Wiskerchen, M. & Muesing, M. A. (1996). Potent human immunodeficiency virus type 1 protease inhibitors that utilize noncoded D-amino acids as P2/P3 ligands. J. Med. Chem. 39, 96-108.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 96-108
-
-
Jungheim, L.N.1
Shepherd, T.A.2
Baxter, A.J.3
Burgess, J.4
Hatch, S.D.5
Lubbehusen, P.6
Wiskerchen, M.7
Muesing, M.A.8
-
19
-
-
0028363160
-
Design of structure-based reverse transcriptase inhibitors
-
Kang, I. & Wang, J. H. (1994). Design of structure-based reverse transcriptase inhibitors. J. Biol. Chem. 269, 12024-12031.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 12024-12031
-
-
Kang, I.1
Wang, J.H.2
-
20
-
-
0030011355
-
Conformation of a non-frameshifting RNA pseudoknot from mouse mammary tumor virus
-
Kang, H., Hines, J. V. & Tinoco, I., Jr (1996) Conformation of a non-frameshifting RNA pseudoknot from mouse mammary tumor virus. J. Mol. Biol. 259, 135-147.
-
(1996)
J. Mol. Biol.
, vol.259
, pp. 135-147
-
-
Kang, H.1
Hines, J.V.2
Tinoco I., Jr.3
-
21
-
-
0026693137
-
Crystal structure at 3.5 Å resolution of HIV-1 reverse transcriptase complexed with an inhibitor
-
Kohlstaedt, L. A., Wang, J., Friedman, J. M., Rice, P. A. & Steitz, T. A. (1992). Crystal structure at 3.5 Å resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science, 256, 1783-1790.
-
(1992)
Science
, vol.256
, pp. 1783-1790
-
-
Kohlstaedt, L.A.1
Wang, J.2
Friedman, J.M.3
Rice, P.A.4
Steitz, T.A.5
-
22
-
-
0027220687
-
Facilitated distortion of the DNA site enhances EcoRI endonuclease-DNA recognition
-
Lesser, D. R., Kurpiewski, M. R., Waters, T., Connolly, B. A. & Jen-Jacobson, L. (1993). Facilitated distortion of the DNA site enhances EcoRI endonuclease-DNA recognition. Proc. Natl Acad. Sci. USA, 90, 7548-7552.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 7548-7552
-
-
Lesser, D.R.1
Kurpiewski, M.R.2
Waters, T.3
Connolly, B.A.4
Jen-Jacobson, L.5
-
23
-
-
0028806725
-
A preliminary study of ritonavir, an inhibitor of HIV-1 protease, to treat HIV-1 infection
-
Markowitz, M., Saag, M. Powderly, W. G., Hurley, A. M., Hsu, A. Z., Valdes, J. M., Henry, D., Sattler, F., La Marca, A., Leonard, J. M. et al. (1995). A preliminary study of ritonavir, an inhibitor of HIV-1 protease, to treat HIV-1 infection. New Eng. J. Med. 333, 1534-1539.
-
(1995)
New Eng. J. Med.
, vol.333
, pp. 1534-1539
-
-
Markowitz, M.1
Saag, M.2
Powderly, W.G.3
Hurley, A.M.4
Hsu, A.Z.5
Valdes, J.M.6
Henry, D.7
Sattler, F.8
La Marca, A.9
Leonard, J.M.10
-
24
-
-
0028998293
-
Design and synthesis of novel inhibitors of HIV-1 reverse transcriptase
-
Maruenda, H. & Johnson, F. (1995). Design and synthesis of novel inhibitors of HIV-1 reverse transcriptase. J. Med. Chem. 38, 2145-2151.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 2145-2151
-
-
Maruenda, H.1
Johnson, F.2
-
25
-
-
0024819449
-
Synthesis of small RNAs using T7 RNA polymerase
-
Milligan, J. F. & Uhlenbeck, O. C. (1989). Synthesis of small RNAs using T7 RNA polymerase. Methods Enzymol. 180, 51-62.
-
(1989)
Methods Enzymol.
, vol.180
, pp. 51-62
-
-
Milligan, J.F.1
Uhlenbeck, O.C.2
-
26
-
-
0029061471
-
Site-specific crosslinking of 4-thiouridine-modified human tRNA(3Lys) to reverse transcriptase from human immunodeficiency virus type I
-
Mishima, Y. & Steitz, J. A. (1995). Site-specific crosslinking of 4-thiouridine-modified human tRNA(3Lys) to reverse transcriptase from human immunodeficiency virus type I. EMBO J. 14, 2679-2687.
-
(1995)
EMBO J.
, vol.14
, pp. 2679-2687
-
-
Mishima, Y.1
Steitz, J.A.2
-
27
-
-
0028838032
-
Molecular dissection of the pseudoknot governing the translational regulation of Escherichia coli ribosomal protein S15
-
Philippe, C., Benard, L., Portier, C., Westhof, E., Ehresmann, B. & Ehresmann, C. (1995). Molecular dissection of the pseudoknot governing the translational regulation of Escherichia coli ribosomal protein S15. Nucl. Acids Res. 23, 18-28.
-
(1995)
Nucl. Acids Res.
, vol.23
, pp. 18-28
-
-
Philippe, C.1
Benard, L.2
Portier, C.3
Westhof, E.4
Ehresmann, B.5
Ehresmann, C.6
-
28
-
-
0027414932
-
The sequence features important for plus strand priming by human immunodeficiency virus type 1 reverse transcriptase
-
Pullen, K. A., Rattray, A. J. & Champoux, J. J. (1993). The sequence features important for plus strand priming by human immunodeficiency virus type 1 reverse transcriptase. J. Biol. Chem. 268, 6221-6227.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 6221-6227
-
-
Pullen, K.A.1
Rattray, A.J.2
Champoux, J.J.3
-
29
-
-
0029645409
-
The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: Lessons for inhibitor design
-
Ren, J., Esnouf, R., Hopkins, A., Ross, C., Jones, Y., Stammers, D. & Stuart, D. (1995). The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design. Structure, 3, 915-926.
-
(1995)
Structure
, vol.3
, pp. 915-926
-
-
Ren, J.1
Esnouf, R.2
Hopkins, A.3
Ross, C.4
Jones, Y.5
Stammers, D.6
Stuart, D.7
-
30
-
-
0027180473
-
An RNA motif that binds ATP
-
Sassanfar, M. & Szostak, J. W. (1993). An RNA motif that binds ATP. Nature, 364, 550-553.
-
(1993)
Nature
, vol.364
, pp. 550-553
-
-
Sassanfar, M.1
Szostak, J.W.2
-
31
-
-
0029165745
-
High-affinity ssDNA inhibitors of the reverse transcriptase of type 1 human immunodeficiency virus
-
Schneider, D. J., Feigon, J., Hostomsky, Z. & Gold, L. (1995). High-affinity ssDNA inhibitors of the reverse transcriptase of type 1 human immunodeficiency virus. Biochemistry, 34, 9599-9610.
-
(1995)
Biochemistry
, vol.34
, pp. 9599-9610
-
-
Schneider, D.J.1
Feigon, J.2
Hostomsky, Z.3
Gold, L.4
-
32
-
-
0028119985
-
A full-coordinate model of the polymerase domain of HIV-1 reverse transcriptase and its interaction with a nucleic acid substrate
-
Setlik, R. F., Meyer, D. J., Shibata, M., Roskwitalski, R., Ornstein, R. L. & Rein, R. (1994). A full-coordinate model of the polymerase domain of HIV-1 reverse transcriptase and its interaction with a nucleic acid substrate. J. Biomol. Struct. Dynam. 12, 37-60.
-
(1994)
J. Biomol. Struct. Dynam.
, vol.12
, pp. 37-60
-
-
Setlik, R.F.1
Meyer, D.J.2
Shibata, M.3
Roskwitalski, R.4
Ornstein, R.L.5
Rein, R.6
-
33
-
-
0028910590
-
The structure of an RNA pseudoknot that causes efficient frameshifting in mouse mammary tumor virus
-
Shen, L. X. & Tinoco, I. J., Jr (1995). The structure of an RNA pseudoknot that causes efficient frameshifting in mouse mammary tumor virus. J. Mol. Biol. 247, 963-978.
-
(1995)
J. Mol. Biol.
, vol.247
, pp. 963-978
-
-
Shen, L.X.1
Tinoco I.J., Jr.2
-
34
-
-
0025194307
-
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
-
Tuerk, C. & Gold, L. (1990). Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science, 249, 505-510.
-
(1990)
Science
, vol.249
, pp. 505-510
-
-
Tuerk, C.1
Gold, L.2
-
35
-
-
0026651981
-
RNA pseudoknots that inhibit human immunodeficiency virus type 1 reverse transcriptase
-
Tuerk, C., MacDougal, S. & Gold, L. (1992). RNA pseudoknots that inhibit human immunodeficiency virus type 1 reverse transcriptase. Proc. Natl Acad. Sci. USA, 89, 6988-6992.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 6988-6992
-
-
Tuerk, C.1
MacDougal, S.2
Gold, L.3
-
36
-
-
0028079067
-
2.2 Å resolution structure of the amino-terminal half of HIV-1 reverse transcriptase (fingers and palm subdomains)
-
Unge, T., Knight, S., Bhikhabhai, R., Lovgren, S., Dauter, Z., Wilson, K. & Strandberg, B. (1994). 2.2 Å resolution structure of the amino-terminal half of HIV-1 reverse transcriptase (fingers and palm subdomains). Structure, 2, 953-961.
-
(1994)
Structure
, vol.2
, pp. 953-961
-
-
Unge, T.1
Knight, S.2
Bhikhabhai, R.3
Lovgren, S.4
Dauter, Z.5
Wilson, K.6
Strandberg, B.7
-
37
-
-
0029041267
-
Benzophenone derivatives: A novel series of potent and selective inhibitors of human immunodeficiency virus type 1 reverse transcriptase
-
Wyatt, P. G., Bethell, R. C., Cammack, N., Charon, D., Dodic, N., Dumaitre, B., Evans, D. N., Green, D. V., Hopewell, P. L., Humber, D. C. et al. (1995). Benzophenone derivatives: a novel series of potent and selective inhibitors of human immunodeficiency virus type 1 reverse transcriptase. J. Med. Chem. 38, 1657-1665.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 1657-1665
-
-
Wyatt, P.G.1
Bethell, R.C.2
Cammack, N.3
Charon, D.4
Dodic, N.5
Dumaitre, B.6
Evans, D.N.7
Green, D.V.8
Hopewell, P.L.9
Humber, D.C.10
|