-
1
-
-
84877120241
-
Olive-oil-derived oleocanthal enhances β-amyloid clearance as a potential neuroprotective mechanism against Alzheimer's disease: in vitro and in vivo studies
-
Abuznait AH, Qosa H, Busnena BA, El Sayed KA, Kaddoumi A (2013) Olive-oil-derived oleocanthal enhances β-amyloid clearance as a potential neuroprotective mechanism against Alzheimer's disease: in vitro and in vivo studies. ACS Chem. Neurosci. 4, 973-982.
-
(2013)
ACS Chem. Neurosci.
, vol.4
, pp. 973-982
-
-
Abuznait, A.H.1
Qosa, H.2
Busnena, B.A.3
El Sayed, K.A.4
Kaddoumi, A.5
-
2
-
-
84856800302
-
Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks
-
Alers S, Löffler AS, Wesselborg S, Stork B (2012) Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks. Mol. Cell. Biol. 32, 2-11.
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 2-11
-
-
Alers, S.1
Löffler, A.S.2
Wesselborg, S.3
Stork, B.4
-
3
-
-
0036846587
-
The associations of diet with serum insulin-like growth factor I and its main binding proteins in 292 women meat-eaters, vegetarians, and vegans
-
Allen NE, Appleby PN, Davey GK, Kaaks R, Rinaldi S, Key TJ (2002) The associations of diet with serum insulin-like growth factor I and its main binding proteins in 292 women meat-eaters, vegetarians, and vegans. Cancer Epidemiol. Biomarkers Prev. 11, 1441-1448.
-
(2002)
Cancer Epidemiol. Biomarkers Prev.
, vol.11
, pp. 1441-1448
-
-
Allen, N.E.1
Appleby, P.N.2
Davey, G.K.3
Kaaks, R.4
Rinaldi, S.5
Key, T.J.6
-
4
-
-
2442587889
-
Breast cancer risk in premenopausal women is inversely associated with consumption of broccoli, a source of isothiocyanates, but is not modified by GST genotype
-
Ambrosone CB, McCann SE, Freudenheim JL, Marshall JR, Zhang Y, Shields PG (2004) Breast cancer risk in premenopausal women is inversely associated with consumption of broccoli, a source of isothiocyanates, but is not modified by GST genotype. J. Nutr. 134, 1134-1138.
-
(2004)
J. Nutr.
, vol.134
, pp. 1134-1138
-
-
Ambrosone, C.B.1
McCann, S.E.2
Freudenheim, J.L.3
Marshall, J.R.4
Zhang, Y.5
Shields, P.G.6
-
5
-
-
84859105496
-
Global Health and Aging, World Health Organization
-
Last accessed on 2 June 2014
-
Anon (2011) Global Health and Aging, World Health Organization. URL: http://www.who.int/ageing/publications/global_health.pdf. Last accessed on 2 June 2014
-
(2011)
-
-
-
6
-
-
84878473064
-
Somatotropic signaling: trade-offs between growth, reproductive development, and longevity
-
Bartke A, Sun LY, Longo V (2013) Somatotropic signaling: trade-offs between growth, reproductive development, and longevity. Physiol. Rev. 93, 571-598.
-
(2013)
Physiol. Rev.
, vol.93
, pp. 571-598
-
-
Bartke, A.1
Sun, L.Y.2
Longo, V.3
-
7
-
-
84893115435
-
The rationale for delaying aging and the prevention of age-related diseases
-
Barzilai N, Rennert G (2012) The rationale for delaying aging and the prevention of age-related diseases. Rambam Maimonides Med. J. 3, e0020.
-
(2012)
Rambam Maimonides Med. J.
, vol.3
, pp. e0020
-
-
Barzilai, N.1
Rennert, G.2
-
8
-
-
34250739903
-
High dietary glycemic load and glycemic index increase risk of cardiovascular disease among middle-aged women: a population-based follow-up study
-
Beulens JWJ, de Bruijne LM, Stolk RP, Peeters PHM, Bots ML, Grobbee DE, van der Schouw YT (2007) High dietary glycemic load and glycemic index increase risk of cardiovascular disease among middle-aged women: a population-based follow-up study. J. Am. Coll. Cardiol. 50, 14-21.
-
(2007)
J. Am. Coll. Cardiol.
, vol.50
, pp. 14-21
-
-
Beulens, J.W.J.1
de Bruijne, L.M.2
Stolk, R.P.3
Peeters, P.H.M.4
Bots, M.L.5
Grobbee, D.E.6
van der Schouw, Y.T.7
-
9
-
-
33847378451
-
Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis
-
Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C (2007) Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA 297, 842-857.
-
(2007)
JAMA
, vol.297
, pp. 842-857
-
-
Bjelakovic, G.1
Nikolova, D.2
Gluud, L.L.3
Simonetti, R.G.4
Gluud, C.5
-
10
-
-
33750029285
-
Aging and immortality conceptual review
-
Blagosklonny MV (2006) Aging and immortality conceptual review. Cell Cycle, 5, 2087-2102.
-
(2006)
Cell Cycle
, vol.5
, pp. 2087-2102
-
-
Blagosklonny, M.V.1
-
11
-
-
0037942739
-
Extended longevity in mice lacking the insulin receptor in adipose tissue
-
Blüher M, Kahn BB, Kahn CR (2003) Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 299, 572-574.
-
(2003)
Science
, vol.299
, pp. 572-574
-
-
Blüher, M.1
Kahn, B.B.2
Kahn, C.R.3
-
12
-
-
79954610780
-
Coffee constituents as modulators of Nrf2 nuclear translocation and ARE (EpRE)-dependent gene expression
-
Boettler U, Sommerfeld K, Volz N, Pahlke G, Teller N, Somoza V, Lang R, Hofmann T, Marko D (2011) Coffee constituents as modulators of Nrf2 nuclear translocation and ARE (EpRE)-dependent gene expression. J. Nutr. Biochem. 22, 426-440.
-
(2011)
J. Nutr. Biochem.
, vol.22
, pp. 426-440
-
-
Boettler, U.1
Sommerfeld, K.2
Volz, N.3
Pahlke, G.4
Teller, N.5
Somoza, V.6
Lang, R.7
Hofmann, T.8
Marko, D.9
-
13
-
-
0038637217
-
Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control
-
Bonafè M, Barbieri M, Marchegiani F, Olivieri F, Ragno E, Giampieri C, Mugianesi E, Centurelli M, Franceschi C, Paolisso G (2003) Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control. J. Clin. Endocrinol. Metab. 88, 3299-3304.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 3299-3304
-
-
Bonafè, M.1
Barbieri, M.2
Marchegiani, F.3
Olivieri, F.4
Ragno, E.5
Giampieri, C.6
Mugianesi, E.7
Centurelli, M.8
Franceschi, C.9
Paolisso, G.10
-
14
-
-
20444446810
-
Glycaemic index methodology
-
Brouns F, Bjorck I, Frayn KN, Gibbs AL, Lang V, Slama G, Wolever TMS (2005) Glycaemic index methodology. Nutr. Res. Rev. 18, 145-171.
-
(2005)
Nutr. Res. Rev.
, vol.18
, pp. 145-171
-
-
Brouns, F.1
Bjorck, I.2
Frayn, K.N.3
Gibbs, A.L.4
Lang, V.5
Slama, G.6
Wolever, T.M.S.7
-
15
-
-
84882767539
-
Inhibition of mTOR signaling by quercetin in cancer treatment and prevention
-
Bruning A (2013) Inhibition of mTOR signaling by quercetin in cancer treatment and prevention. Anticancer Agents Med. Chem. 13, 1025-1031.
-
(2013)
Anticancer Agents Med. Chem.
, vol.13
, pp. 1025-1031
-
-
Bruning, A.1
-
16
-
-
80053389356
-
Chocolate consumption and cardiometabolic disorders: systematic review and meta-analysis
-
Buitrago-Lopez A, Sanderson J, Johnson L, Warnakula S, Wood A, Di Angelantonio E, Franco OH (2011) Chocolate consumption and cardiometabolic disorders: systematic review and meta-analysis. BMJ 343, d4488.
-
(2011)
BMJ
, vol.343
, pp. d4488
-
-
Buitrago-Lopez, A.1
Sanderson, J.2
Johnson, L.3
Warnakula, S.4
Wood, A.5
Di Angelantonio, E.6
Franco, O.H.7
-
17
-
-
34250844410
-
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework
-
Calabrese EJ, Bachmann KA, Bailer AJ, Bolger PM, Borak J, Cai L, Cedergreen N, Cherian MG, Chiueh CC, Clarkson TW, Cook RR, Diamond DM, Doolittle DJ, Dorato MA, Duke SO, Feinendegen L, Gardner DE, Hart RW, Hastings KL, Hayes AW, Hoffmann GR, Ives JA, Jaworowski Z, Johnson TE, Jonas WB, Kaminski NE, Keller JG, Klaunig JE, Knudsen TB, Kozumbo WJ, Lettieri T, Liu S-Z, Maisseu A, Maynard KI, Masoro EJ, McClellan RO, Mehendale HM, Mothersill C, Newlin DB, Nigg HN, Oehme FW, Phalen RF, Philbert MA, Rattan SIS, Riviere JE, Rodricks J, Sapolsky RM, Scott BR, Seymour C, Sinclair DA, Smith-Sonneborn J, Snow ET, Spear L, Stevenson DE, Thomas Y, Tubiana M, Williams GM, Mattson MP (2007) Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol. Appl. Pharmacol. 222, 122-128.
-
(2007)
Toxicol. Appl. Pharmacol.
, vol.222
, pp. 122-128
-
-
Calabrese, E.J.1
Bachmann, K.A.2
Bailer, A.J.3
Bolger, P.M.4
Borak, J.5
Cai, L.6
Cedergreen, N.7
Cherian, M.G.8
Chiueh, C.C.9
Clarkson, T.W.10
Cook, R.R.11
Diamond, D.M.12
Doolittle, D.J.13
Dorato, M.A.14
Duke, S.O.15
Feinendegen, L.16
Gardner, D.E.17
Hart, R.W.18
Hastings, K.L.19
Hayes, A.W.20
Hoffmann, G.R.21
Ives, J.A.22
Jaworowski, Z.23
Johnson, T.E.24
Jonas, W.B.25
Kaminski, N.E.26
Keller, J.G.27
Klaunig, J.E.28
Knudsen, T.B.29
Kozumbo, W.J.30
Lettieri, T.31
Liu, S.-Z.32
Maisseu, A.33
Maynard, K.I.34
Masoro, E.J.35
McClellan, R.O.36
Mehendale, H.M.37
Mothersill, C.38
Newlin, D.B.39
Nigg, H.N.40
Oehme, F.W.41
Phalen, R.F.42
Philbert, M.A.43
Rattan, S.I.S.44
Riviere, J.E.45
Rodricks, J.46
Sapolsky, R.M.47
Scott, B.R.48
Seymour, C.49
Sinclair, D.A.50
Smith-Sonneborn, J.51
Snow, E.T.52
Spear, L.53
Stevenson, D.E.54
Thomas, Y.55
Tubiana, M.56
Williams, G.M.57
Mattson, M.P.58
more..
-
18
-
-
0033935482
-
Marginal protein intake results in reduced plasma IGF-I levels and skeletal muscle fiber atrophy in elderly women
-
Castaneda C, Gordon PL, Fielding RA, Evans WJ, Crim MC (2000) Marginal protein intake results in reduced plasma IGF-I levels and skeletal muscle fiber atrophy in elderly women. J. Nutr. Health Aging 4, 85-90.
-
(2000)
J. Nutr. Health Aging
, vol.4
, pp. 85-90
-
-
Castaneda, C.1
Gordon, P.L.2
Fielding, R.A.3
Evans, W.J.4
Crim, M.C.5
-
19
-
-
84861701419
-
A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension
-
Cavuoto P, Fenech MF (2012) A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension. Cancer Treat. Rev. 38, 726-736.
-
(2012)
Cancer Treat. Rev.
, vol.38
, pp. 726-736
-
-
Cavuoto, P.1
Fenech, M.F.2
-
20
-
-
84902185782
-
Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression
-
Cheng C-W, Adams GB, Perin L, Wei M, Zhou X, Lam BS, Da Sacco S, Mirisola M, Quinn DI, Dorff TB, Kopchick JJ, Longo VD (2014) Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression. Cell Stem Cell 14, 810-823.
-
(2014)
Cell Stem Cell
, vol.14
, pp. 810-823
-
-
Cheng, C.-W.1
Adams, G.B.2
Perin, L.3
Wei, M.4
Zhou, X.5
Lam, B.S.6
Da Sacco, S.7
Mirisola, M.8
Quinn, D.I.9
Dorff, T.B.10
Kopchick, J.J.11
Longo, V.D.12
-
22
-
-
0038646354
-
Cardiovascular function in acromegaly
-
Clayton RN (2003) Cardiovascular function in acromegaly. Endocr. Rev. 24, 272-277.
-
(2003)
Endocr. Rev.
, vol.24
, pp. 272-277
-
-
Clayton, R.N.1
-
23
-
-
67650439330
-
Caloric restriction delays disease onset and mortality in rhesus monkeys
-
Colman RJ, Anderson RM, Johnson SC, Kastman EK, Kosmatka KJ, Beasley TM, Allison DB, Cruzen C, Simmons HA, Kemnitz JW, Weindruch R (2009) Caloric restriction delays disease onset and mortality in rhesus monkeys. Science 325, 201-204.
-
(2009)
Science
, vol.325
, pp. 201-204
-
-
Colman, R.J.1
Anderson, R.M.2
Johnson, S.C.3
Kastman, E.K.4
Kosmatka, K.J.5
Beasley, T.M.6
Allison, D.B.7
Cruzen, C.8
Simmons, H.A.9
Kemnitz, J.W.10
Weindruch, R.11
-
24
-
-
84897524640
-
Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys
-
Colman RJ, Beasley TM, Kemnitz JW, Johnson SC, Weindruch R, Anderson RM (2014) Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys. Nat. Commun. 5, 3557.
-
(2014)
Nat. Commun.
, vol.5
, pp. 3557
-
-
Colman, R.J.1
Beasley, T.M.2
Kemnitz, J.W.3
Johnson, S.C.4
Weindruch, R.5
Anderson, R.M.6
-
25
-
-
56349168452
-
Autophagy and aging: keeping that old broom working
-
Cuervo AM (2008) Autophagy and aging: keeping that old broom working. Trends Genet. 24, 604-612.
-
(2008)
Trends Genet.
, vol.24
, pp. 604-612
-
-
Cuervo, A.M.1
-
26
-
-
0028235692
-
Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease
-
De Lorgeril M, Renaud S, Mamelle N, Salen P, Martin JL, Monjaud I, Guidollet J, Touboul P, Delaye J (1994) Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease. Lancet 343, 1454-1459.
-
(1994)
Lancet
, vol.343
, pp. 1454-1459
-
-
De Lorgeril, M.1
Renaud, S.2
Mamelle, N.3
Salen, P.4
Martin, J.L.5
Monjaud, I.6
Guidollet, J.7
Touboul, P.8
Delaye, J.9
-
27
-
-
84865458738
-
Benefits in cognitive function, blood pressure, and insulin resistance through cocoa flavanol consumption in elderly subjects with mild cognitive impairment: the Cocoa, Cognition, and Aging (CoCoA) study
-
Desideri G, Kwik-Uribe C, Grassi D, Necozione S, Ghiadoni L, Mastroiacovo D, Raffaele A, Ferri L, Bocale R, Lechiara MC, Marini C, Ferri C (2012) Benefits in cognitive function, blood pressure, and insulin resistance through cocoa flavanol consumption in elderly subjects with mild cognitive impairment: the Cocoa, Cognition, and Aging (CoCoA) study. Hypertension 60, 794-801.
-
(2012)
Hypertension
, vol.60
, pp. 794-801
-
-
Desideri, G.1
Kwik-Uribe, C.2
Grassi, D.3
Necozione, S.4
Ghiadoni, L.5
Mastroiacovo, D.6
Raffaele, A.7
Ferri, L.8
Bocale, R.9
Lechiara, M.C.10
Marini, C.11
Ferri, C.12
-
28
-
-
84862859054
-
Effects of dietary composition on energy expenditure during weight-loss maintenance
-
Ebbeling CB, Swain JF, Feldman HA, Wong WW, Hachey DL, Garcia-Lago E, Ludwig DS (2012) Effects of dietary composition on energy expenditure during weight-loss maintenance. JAMA 307, 2627-2634.
-
(2012)
JAMA
, vol.307
, pp. 2627-2634
-
-
Ebbeling, C.B.1
Swain, J.F.2
Feldman, H.A.3
Wong, W.W.4
Hachey, D.L.5
Garcia-Lago, E.6
Ludwig, D.S.7
-
29
-
-
84865592978
-
Amino acids and mTORC1: from lysosomes to disease
-
Efeyan A, Zoncu R, Sabatini DM (2012) Amino acids and mTORC1: from lysosomes to disease. Trends Mol. Med. 18, 524-533.
-
(2012)
Trends Mol. Med.
, vol.18
, pp. 524-533
-
-
Efeyan, A.1
Zoncu, R.2
Sabatini, D.M.3
-
30
-
-
84875027603
-
High intakes of protein and processed meat associate with increased incidence of type 2 diabetes
-
Ericson U, Sonestedt E, Gullberg B, Hellstrand S, Hindy G, Wirfält E, Orho-Melander M (2013) High intakes of protein and processed meat associate with increased incidence of type 2 diabetes. Br. J. Nutr. 109, 1143-1153.
-
(2013)
Br. J. Nutr.
, vol.109
, pp. 1143-1153
-
-
Ericson, U.1
Sonestedt, E.2
Gullberg, B.3
Hellstrand, S.4
Hindy, G.5
Wirfält, E.6
Orho-Melander, M.7
-
31
-
-
0023864642
-
Effects of ingestion of high protein or excess methionine diets by rats for two years
-
Fau D, Peret J, Hadjiisky P (1988) Effects of ingestion of high protein or excess methionine diets by rats for two years. J. Nutr. 118, 128-133.
-
(1988)
J. Nutr.
, vol.118
, pp. 128-133
-
-
Fau, D.1
Peret, J.2
Hadjiisky, P.3
-
32
-
-
2342647592
-
Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans
-
Fontana L, Meyer TE, Klein S, Holloszy JO (2004) Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Proc. Natl Acad. Sci. USA 101, 6659-6663.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 6659-6663
-
-
Fontana, L.1
Meyer, T.E.2
Klein, S.3
Holloszy, J.O.4
-
33
-
-
77951176737
-
Extending healthy life span-from yeast to humans
-
Fontana L, Partridge L, Longo VD (2010) Extending healthy life span-from yeast to humans. Science 328, 321-326.
-
(2010)
Science
, vol.328
, pp. 321-326
-
-
Fontana, L.1
Partridge, L.2
Longo, V.D.3
-
35
-
-
79551537131
-
Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal models
-
Frydman-Marom A, Levin A, Farfara D, Benromano T, Scherzer-Attali R, Peled S, Vassar R, Segal D, Gazit E, Frenkel D, Ovadia M (2011) Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal models. PLoS ONE 6, e16564.
-
(2011)
PLoS ONE
, vol.6
, pp. e16564
-
-
Frydman-Marom, A.1
Levin, A.2
Farfara, D.3
Benromano, T.4
Scherzer-Attali, R.5
Peled, S.6
Vassar, R.7
Segal, D.8
Gazit, E.9
Frenkel, D.10
Ovadia, M.11
-
36
-
-
84874726175
-
Alternative perspectives on aging in caenorhabditis elegans: reactive oxygen species or hyperfunction?
-
Gems D, de la Guardia Y (2012) Alternative perspectives on aging in caenorhabditis elegans: reactive oxygen species or hyperfunction? Antioxid. Redox Signal. 00, 1-9.
-
(2012)
Antioxid. Redox Signal.
, vol.0
, pp. 1-9
-
-
Gems, D.1
de la Guardia, Y.2
-
37
-
-
0141893375
-
M-CSF, TNFalpha and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase
-
Glantschnig H, Fisher JE, Wesolowski G, Rodan GA, Reszka AA (2003) M-CSF, TNFalpha and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase. Cell Death Differ. 10, 1165-1177.
-
(2003)
Cell Death Differ.
, vol.10
, pp. 1165-1177
-
-
Glantschnig, H.1
Fisher, J.E.2
Wesolowski, G.3
Rodan, G.A.4
Reszka, A.A.5
-
38
-
-
77956623471
-
Diet and cancer prevention: contributions from the European Prospective Investigation into Cancer and Nutrition (EPIC) study
-
Gonzalez CA, Riboli E (2010) Diet and cancer prevention: contributions from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Eur. J. Cancer 46, 2555-2562.
-
(2010)
Eur. J. Cancer
, vol.46
, pp. 2555-2562
-
-
Gonzalez, C.A.1
Riboli, E.2
-
39
-
-
72949117234
-
Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila
-
Grandison RC, Piper MDW, Partridge L (2009) Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila. Nature 462, 1061-1064.
-
(2009)
Nature
, vol.462
, pp. 1061-1064
-
-
Grandison, R.C.1
Piper, M.D.W.2
Partridge, L.3
-
40
-
-
79951938474
-
Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans
-
70ra13
-
Guevara-Aguirre J, Balasubramanian P, Guevara-Aguirre M, Wei M, Madia F, Cheng C-W, Hwang D, Martin-Montalvo A, Saavedra J, Ingles S, de Cabo R, Cohen P, Longo VD (2011) Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans. Sci. Transl. Med. 3, 70ra13.
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Guevara-Aguirre, J.1
Balasubramanian, P.2
Guevara-Aguirre, M.3
Wei, M.4
Madia, F.5
Cheng, C.-W.6
Hwang, D.7
Martin-Montalvo, A.8
Saavedra, J.9
Ingles, S.10
de Cabo, R.11
Cohen, P.12
Longo, V.D.13
-
41
-
-
28044434071
-
Effect of intermittent fasting and refeeding on insulin action in healthy men
-
Halberg N, Henriksen M, Söderhamn N, Stallknecht B, Ploug T, Schjerling P, Dela F (2005) Effect of intermittent fasting and refeeding on insulin action in healthy men. J. Appl. Physiol. 99, 2128-2136.
-
(2005)
J. Appl. Physiol.
, vol.99
, pp. 2128-2136
-
-
Halberg, N.1
Henriksen, M.2
Söderhamn, N.3
Stallknecht, B.4
Ploug, T.5
Schjerling, P.6
Dela, F.7
-
42
-
-
84872138910
-
Reproduction, fat metabolism, and life span: what is the connection?
-
Hansen M, Flatt T, Aguilaniu H (2013) Reproduction, fat metabolism, and life span: what is the connection? Cell Metab. 17, 10-19.
-
(2013)
Cell Metab.
, vol.17
, pp. 10-19
-
-
Hansen, M.1
Flatt, T.2
Aguilaniu, H.3
-
43
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wilkinson JE, Frenkel K, Carter CS, Pahor M, Javors MA, Fernandez E, Miller RA (2009) Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 460, 392-395.
-
(2009)
Nature
, vol.460
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
Nelson, J.F.4
Astle, C.M.5
Flurkey, K.6
Nadon, N.L.7
Wilkinson, J.E.8
Frenkel, K.9
Carter, C.S.10
Pahor, M.11
Javors, M.A.12
Fernandez, E.13
Miller, R.A.14
-
44
-
-
43149099706
-
The cancer chemopreventive actions of phytochemicals derived from glucosinolates
-
Hayes JD, Kelleher MO, Eggleston IM (2008) The cancer chemopreventive actions of phytochemicals derived from glucosinolates. Eur. J. Nutr. 47(Suppl 2), 73-88.
-
(2008)
Eur. J. Nutr.
, vol.47
, pp. 73-88
-
-
Hayes, J.D.1
Kelleher, M.O.2
Eggleston, I.M.3
-
45
-
-
33645526333
-
Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: a randomized controlled trial
-
Heilbronn LK, de Jonge L, Frisard MI, DeLany JP, Larson-Meyer DE, Rood J, Nguyen T, Martin CK, Volaufova J, Most MM, Greenway FL, Smith SR, Deutsch WA, Williamson DA, Ravussin E (2006) Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: a randomized controlled trial. JAMA 295, 1539-1548.
-
(2006)
JAMA
, vol.295
, pp. 1539-1548
-
-
Heilbronn, L.K.1
de Jonge, L.2
Frisard, M.I.3
DeLany, J.P.4
Larson-Meyer, D.E.5
Rood, J.6
Nguyen, T.7
Martin, C.K.8
Volaufova, J.9
Most, M.M.10
Greenway, F.L.11
Smith, S.R.12
Deutsch, W.A.13
Williamson, D.A.14
Ravussin, E.15
-
46
-
-
1842301673
-
An insulin index of foods: the insulin demand generated by 1000-kJ portions of common foods
-
Holt SH, Miller JC, Petocz P (1997) An insulin index of foods: the insulin demand generated by 1000-kJ portions of common foods. Am. J. Clin. Nutr. 66, 1264-1276.
-
(1997)
Am. J. Clin. Nutr.
, vol.66
, pp. 1264-1276
-
-
Holt, S.H.1
Miller, J.C.2
Petocz, P.3
-
47
-
-
0347664057
-
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
-
Holzenberger M, Dupont J, Ducos B, Leneuve P, Géloën A, Even PC, Cervera P, Le Bouc Y (2003) IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 421, 182-187.
-
(2003)
Nature
, vol.421
, pp. 182-187
-
-
Holzenberger, M.1
Dupont, J.2
Ducos, B.3
Leneuve, P.4
Géloën, A.5
Even, P.C.6
Cervera, P.7
Le Bouc, Y.8
-
48
-
-
84866365418
-
Function and regulation of lipid biology in caenorhabditis elegans aging
-
Hou NS, Taubert S (2012) Function and regulation of lipid biology in caenorhabditis elegans aging. Front. Physiol. 3, 143.
-
(2012)
Front. Physiol.
, vol.3
, pp. 143
-
-
Hou, N.S.1
Taubert, S.2
-
49
-
-
38149099252
-
Dietary protein intake is associated with lean mass change in older, community-dwelling adults: the Health, Aging, and Body Composition (Health ABC) Study
-
Houston DK, Nicklas BJ, Ding J, Harris TB, Tylavsky FA, Newman AB, Lee JS, Sahyoun NR, Visser M, Kritchevsky SB (2008) Dietary protein intake is associated with lean mass change in older, community-dwelling adults: the Health, Aging, and Body Composition (Health ABC) Study. Am. J. Clin. Nutr. 87, 150-155.
-
(2008)
Am. J. Clin. Nutr.
, vol.87
, pp. 150-155
-
-
Houston, D.K.1
Nicklas, B.J.2
Ding, J.3
Harris, T.B.4
Tylavsky, F.A.5
Newman, A.B.6
Lee, J.S.7
Sahyoun, N.R.8
Visser, M.9
Kritchevsky, S.B.10
-
52
-
-
33746889956
-
Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice
-
Hu R, Xu C, Shen G, Jain MR, Khor TO, Gopalkrishnan A, Lin W, Reddy B, Chan JY, Kong A-NT (2006) Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice. Cancer Lett. 243, 170-192.
-
(2006)
Cancer Lett.
, vol.243
, pp. 170-192
-
-
Hu, R.1
Xu, C.2
Shen, G.3
Jain, M.R.4
Khor, T.O.5
Gopalkrishnan, A.6
Lin, W.7
Reddy, B.8
Chan, J.Y.9
Kong, A.-N.10
-
53
-
-
0023838776
-
The influence of dietary protein source on longevity and age-related disease processes of Fischer rats
-
Iwasaki K, Gleiser CA, Masoro EJ, McMahan CA, Seo EJ, Yu BP (1988) The influence of dietary protein source on longevity and age-related disease processes of Fischer rats. J. Gerontol. 43, B5-B12.
-
(1988)
J. Gerontol.
, vol.43
, pp. B5-B12
-
-
Iwasaki, K.1
Gleiser, C.A.2
Masoro, E.J.3
McMahan, C.A.4
Seo, E.J.5
Yu, B.P.6
-
54
-
-
84884676252
-
Nutrient signaling to mTOR and cell growth
-
Jewell JL, Guan K-L (2013) Nutrient signaling to mTOR and cell growth. Trends Biochem. Sci. 38, 233-242.
-
(2013)
Trends Biochem. Sci.
, vol.38
, pp. 233-242
-
-
Jewell, J.L.1
Guan, K.-L.2
-
55
-
-
84872527628
-
mTOR is a key modulator of ageing and age-related disease
-
Johnson SC, Rabinovitch PS, Kaeberlein M (2013) mTOR is a key modulator of ageing and age-related disease. Nature 493, 338-345.
-
(2013)
Nature
, vol.493
, pp. 338-345
-
-
Johnson, S.C.1
Rabinovitch, P.S.2
Kaeberlein, M.3
-
56
-
-
84858000209
-
The sirtuin SIRT6 regulates lifespan in male mice
-
Kanfi Y, Naiman S, Amir G, Peshti V, Zinman G, Nahum L, Bar-Joseph Z, Cohen HY (2012) The sirtuin SIRT6 regulates lifespan in male mice. Nature 483, 218-221.
-
(2012)
Nature
, vol.483
, pp. 218-221
-
-
Kanfi, Y.1
Naiman, S.2
Amir, G.3
Peshti, V.4
Zinman, G.5
Nahum, L.6
Bar-Joseph, Z.7
Cohen, H.Y.8
-
57
-
-
3042648746
-
Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway
-
Kapahi P, Zid BM, Harper T, Koslover D, Sapin V, Benzer S (2004) Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway. Curr. Biol. 14, 885-890.
-
(2004)
Curr. Biol.
, vol.14
, pp. 885-890
-
-
Kapahi, P.1
Zid, B.M.2
Harper, T.3
Koslover, D.4
Sapin, V.5
Benzer, S.6
-
58
-
-
77950200010
-
The genetics of ageing
-
Kenyon CJ (2010) The genetics of ageing. Nature 464, 504-512.
-
(2010)
Nature
, vol.464
, pp. 504-512
-
-
Kenyon, C.J.1
-
59
-
-
0032822303
-
Serum levels of advanced glycation end products are increased in patients with type 2 diabetes and coronary heart disease
-
Kilhovd BK, Berg TJ, Birkeland KI, Thorsby P, Hanssen KF (1999) Serum levels of advanced glycation end products are increased in patients with type 2 diabetes and coronary heart disease. Diabetes Care 22, 1543-1548.
-
(1999)
Diabetes Care
, vol.22
, pp. 1543-1548
-
-
Kilhovd, B.K.1
Berg, T.J.2
Birkeland, K.I.3
Thorsby, P.4
Hanssen, K.F.5
-
60
-
-
9644270707
-
Association analysis between longevity in the Japanese population and polymorphic variants of genes involved in insulin and insulin-like growth factor 1 signaling pathways
-
Kojima T, Kamei H, Aizu T, Arai Y, Takayama M, Nakazawa S, Ebihara Y, Inagaki H, Masui Y, Gondo Y, Sakaki Y, Hirose N (2004) Association analysis between longevity in the Japanese population and polymorphic variants of genes involved in insulin and insulin-like growth factor 1 signaling pathways. Exp. Gerontol. 39, 1595-1598.
-
(2004)
Exp. Gerontol.
, vol.39
, pp. 1595-1598
-
-
Kojima, T.1
Kamei, H.2
Aizu, T.3
Arai, Y.4
Takayama, M.5
Nakazawa, S.6
Ebihara, Y.7
Inagaki, H.8
Masui, Y.9
Gondo, Y.10
Sakaki, Y.11
Hirose, N.12
-
61
-
-
0036313574
-
Mechanism of amino acid-induced skeletal muscle insulin resistance in humans
-
Krebs M, Krssak M, Bernroider E, Anderwald C, Brehm A, Meyerspeer M, Nowotny P, Roth E, Waldhäusl W, Roden M (2002) Mechanism of amino acid-induced skeletal muscle insulin resistance in humans. Diabetes 51, 599-605.
-
(2002)
Diabetes
, vol.51
, pp. 599-605
-
-
Krebs, M.1
Krssak, M.2
Bernroider, E.3
Anderwald, C.4
Brehm, A.5
Meyerspeer, M.6
Nowotny, P.7
Roth, E.8
Waldhäusl, W.9
Roden, M.10
-
62
-
-
84863229916
-
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy
-
124ra27
-
Lee C, Raffaghello L, Brandhorst S, Safdie FM, Bianchi G, Martin-Montalvo A, Pistoia V, Wei M, Hwang S, Merlino A, Emionite L, de Cabo R, Longo VD (2012) Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy. Sci. Transl. Med. 4, 124ra27.
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Lee, C.1
Raffaghello, L.2
Brandhorst, S.3
Safdie, F.M.4
Bianchi, G.5
Martin-Montalvo, A.6
Pistoia, V.7
Wei, M.8
Hwang, S.9
Merlino, A.10
Emionite, L.11
de Cabo, R.12
Longo, V.D.13
-
63
-
-
0017238186
-
Dietary protein, life-span, and biochemical variables in female mice
-
Leto S, Kokkonen GC, Barrows CH (1976) Dietary protein, life-span, and biochemical variables in female mice. J. Gerontol. 31, 144-148.
-
(1976)
J. Gerontol.
, vol.31
, pp. 144-148
-
-
Leto, S.1
Kokkonen, G.C.2
Barrows, C.H.3
-
64
-
-
84895727751
-
Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population
-
Levine ME, Suarez JA, Brandhorst S, Balasubramanian P, Cheng C-W, Madia F, Fontana L, Mirisola MG, Guevara-Aguirre J, Wan J, Passarino G, Kennedy BK, Wei M, Cohen P, Crimmins EM, Longo VD (2014) Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population. Cell Metab. 19, 407-417.
-
(2014)
Cell Metab.
, vol.19
, pp. 407-417
-
-
Levine, M.E.1
Suarez, J.A.2
Brandhorst, S.3
Balasubramanian, P.4
Cheng, C.-W.5
Madia, F.6
Fontana, L.7
Mirisola, M.G.8
Guevara-Aguirre, J.9
Wan, J.10
Passarino, G.11
Kennedy, B.K.12
Wei, M.13
Cohen, P.14
Crimmins, E.M.15
Longo, V.D.16
-
65
-
-
80054091845
-
Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol
-
Lim EL, Hollingsworth KG, Aribisala BS, Chen MJ, Mathers JC, Taylor R (2011) Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol. Diabetologia 54, 2506-2514.
-
(2011)
Diabetologia
, vol.54
, pp. 2506-2514
-
-
Lim, E.L.1
Hollingsworth, K.G.2
Aribisala, B.S.3
Chen, M.J.4
Mathers, J.C.5
Taylor, R.6
-
66
-
-
0034115061
-
A prospective study of dietary glycemic load, carbohydrate intake, and risk of coronary heart disease in US women
-
Liu S, Willett WC, Stampfer MJ, Hu FB, Franz M, Sampson L, Hennekens CH, Manson JE (2000) A prospective study of dietary glycemic load, carbohydrate intake, and risk of coronary heart disease in US women. Am. J. Clin. Nutr. 71, 1455-1461.
-
(2000)
Am. J. Clin. Nutr.
, vol.71
, pp. 1455-1461
-
-
Liu, S.1
Willett, W.C.2
Stampfer, M.J.3
Hu, F.B.4
Franz, M.5
Sampson, L.6
Hennekens, C.H.7
Manson, J.E.8
-
67
-
-
78449241484
-
Resveratrol inhibits mTOR signaling by promoting the interaction between mTOR and DEPTOR
-
Liu M, Wilk SA, Wang A, Zhou L, Wang R-H, Ogawa W, Deng C, Dong LQ, Liu F (2010) Resveratrol inhibits mTOR signaling by promoting the interaction between mTOR and DEPTOR. J. Biol. Chem. 285, 36387-36394.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 36387-36394
-
-
Liu, M.1
Wilk, S.A.2
Wang, A.3
Zhou, L.4
Wang, R.-H.5
Ogawa, W.6
Deng, C.7
Dong, L.Q.8
Liu, F.9
-
68
-
-
49449112344
-
Lowered methionine ingestion as responsible for the decrease in rodent mitochondrial oxidative stress in protein and dietary restriction possible implications for humans
-
López-Torres M, Barja G (2008) Lowered methionine ingestion as responsible for the decrease in rodent mitochondrial oxidative stress in protein and dietary restriction possible implications for humans. Biochim. Biophys. Acta 1780, 1337-1347.
-
(2008)
Biochim. Biophys. Acta
, vol.1780
, pp. 1337-1347
-
-
López-Torres, M.1
Barja, G.2
-
69
-
-
84863092148
-
Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes
-
Lu T, Sheng H, Wu J, Cheng Y, Zhu J, Chen Y (2012) Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr. Res. 32, 408-412.
-
(2012)
Nutr. Res.
, vol.32
, pp. 408-412
-
-
Lu, T.1
Sheng, H.2
Wu, J.3
Cheng, Y.4
Zhu, J.5
Chen, Y.6
-
70
-
-
84896295961
-
mTOR inhibition: a promising strategy for stabilization of atherosclerotic plaques
-
Martinet W, De Loof H, De Meyer GRY (2014) mTOR inhibition: a promising strategy for stabilization of atherosclerotic plaques. Atherosclerosis 233, 601-607.
-
(2014)
Atherosclerosis
, vol.233
, pp. 601-607
-
-
Martinet, W.1
De Loof, H.2
De Meyer, G.R.Y.3
-
71
-
-
84907063686
-
PI3K/AKT signaling pathway and cancer: an updated review
-
Martini M, De Santis M, Braccini L, Gulluni F, Hirsch E (2014) PI3K/AKT signaling pathway and cancer: an updated review. Ann. Med., 46, 1-12.
-
(2014)
Ann. Med.
, vol.46
, pp. 1-12
-
-
Martini, M.1
De Santis, M.2
Braccini, L.3
Gulluni, F.4
Hirsch, E.5
-
72
-
-
84866163081
-
Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study
-
Mattison JA, Roth GS, Beasley TM, Tilmont EM, Handy AM, Herbert RL, Longo DL, Allison DB, Young JE, Bryant M, Barnard D, Ward WF, Qi W, Ingram DK, de Cabo R (2012) Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study. Nature 489, 318-321.
-
(2012)
Nature
, vol.489
, pp. 318-321
-
-
Mattison, J.A.1
Roth, G.S.2
Beasley, T.M.3
Tilmont, E.M.4
Handy, A.M.5
Herbert, R.L.6
Longo, D.L.7
Allison, D.B.8
Young, J.E.9
Bryant, M.10
Barnard, D.11
Ward, W.F.12
Qi, W.13
Ingram, D.K.14
de Cabo, R.15
-
73
-
-
57749196739
-
The low-methionine content of vegan diets may make methionine restriction feasible as a life extension strategy
-
McCarty MF, Barroso-Aranda J, Contreras F (2009) The low-methionine content of vegan diets may make methionine restriction feasible as a life extension strategy. Med. Hypotheses 72, 125-128.
-
(2009)
Med. Hypotheses
, vol.72
, pp. 125-128
-
-
McCarty, M.F.1
Barroso-Aranda, J.2
Contreras, F.3
-
74
-
-
73949102423
-
A 5-year cohort study of the effects of high protein intake on lean mass and BMC in elderly postmenopausal women
-
Meng X, Zhu K, Devine A, Kerr DA, Binns CW, Prince RL (2009) A 5-year cohort study of the effects of high protein intake on lean mass and BMC in elderly postmenopausal women. J. Bone Miner. Res. 24, 1827-1834.
-
(2009)
J. Bone Miner. Res.
, vol.24
, pp. 1827-1834
-
-
Meng, X.1
Zhu, K.2
Devine, A.3
Kerr, D.A.4
Binns, C.W.5
Prince, R.L.6
-
75
-
-
0034122983
-
Carbohydrates, dietary fiber, and incident type 2 diabetes in older women
-
Meyer KA, Kushi LH, Jacobs DR, Slavin J, Sellers TA, Folsom AR (2000) Carbohydrates, dietary fiber, and incident type 2 diabetes in older women. Am. J. Clin. Nutr. 71, 921-930.
-
(2000)
Am. J. Clin. Nutr.
, vol.71
, pp. 921-930
-
-
Meyer, K.A.1
Kushi, L.H.2
Jacobs, D.R.3
Slavin, J.4
Sellers, T.A.5
Folsom, A.R.6
-
76
-
-
30344435943
-
Long-term caloric restriction ameliorates the decline in diastolic function in humans
-
Meyer TE, Kovács SJ, Ehsani AA, Klein S, Holloszy JO, Fontana L (2006) Long-term caloric restriction ameliorates the decline in diastolic function in humans. J. Am. Coll. Cardiol. 47, 398-402.
-
(2006)
J. Am. Coll. Cardiol.
, vol.47
, pp. 398-402
-
-
Meyer, T.E.1
Kovács, S.J.2
Ehsani, A.A.3
Klein, S.4
Holloszy, J.O.5
Fontana, L.6
-
77
-
-
84901743802
-
Serine- and threonine/valine-dependent activation of PDK and Tor orthologs converge on Sch9 to promote aging
-
Mirisola MG, Taormina G, Fabrizio P, Wei M, Hu J, Longo VD (2014) Serine- and threonine/valine-dependent activation of PDK and Tor orthologs converge on Sch9 to promote aging. PLoS Genet. 10, e1004113.
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004113
-
-
Mirisola, M.G.1
Taormina, G.2
Fabrizio, P.3
Wei, M.4
Hu, J.5
Longo, V.D.6
-
78
-
-
79961003604
-
New insights on the interaction mechanism between tau protein and oleocanthal, an extra-virgin olive-oil bioactive component
-
Monti MC, Margarucci L, Tosco A, Riccio R, Casapullo A (2011) New insights on the interaction mechanism between tau protein and oleocanthal, an extra-virgin olive-oil bioactive component. Food Funct. 2, 423-428.
-
(2011)
Food Funct.
, vol.2
, pp. 423-428
-
-
Monti, M.C.1
Margarucci, L.2
Tosco, A.3
Riccio, R.4
Casapullo, A.5
-
79
-
-
35148864410
-
Dietary glycemic index and glycemic load are associated with high-density-lipoprotein cholesterol at baseline but not with increased risk of diabetes in the Whitehall II study
-
Mosdøl A, Witte DR, Frost G, Marmot MG, Brunner EJ (2007) Dietary glycemic index and glycemic load are associated with high-density-lipoprotein cholesterol at baseline but not with increased risk of diabetes in the Whitehall II study. Am. J. Clin. Nutr. 86, 988-994.
-
(2007)
Am. J. Clin. Nutr.
, vol.86
, pp. 988-994
-
-
Mosdøl, A.1
Witte, D.R.2
Frost, G.3
Marmot, M.G.4
Brunner, E.J.5
-
80
-
-
84883774624
-
Fruit consumption and risk of type 2 diabetes: results from three prospective longitudinal cohort studies
-
Muraki I, Imamura F, Manson JE, Hu FB, Willett WC, van Dam RM, Sun Q (2013) Fruit consumption and risk of type 2 diabetes: results from three prospective longitudinal cohort studies. BMJ 347, f5001.
-
(2013)
BMJ
, vol.347
, pp. f5001
-
-
Muraki, I.1
Imamura, F.2
Manson, J.E.3
Hu, F.B.4
Willett, W.C.5
van Dam, R.M.6
Sun, Q.7
-
81
-
-
84879026548
-
PI3-kinase/Akt/mTOR signaling: impaired on/off switches in aging, cognitive decline and Alzheimer's disease
-
O' Neill C (2013) PI3-kinase/Akt/mTOR signaling: impaired on/off switches in aging, cognitive decline and Alzheimer's disease. Exp. Gerontol. 48, 647-653.
-
(2013)
Exp. Gerontol.
, vol.48
, pp. 647-653
-
-
O' Neill, C.1
-
82
-
-
84864395390
-
Insulin and IGF-1 signalling: longevity, protein homoeostasis and Alzheimer's disease
-
O'Neill C, Kiely AP, Coakley MF, Manning S, Long-Smith CM (2012) Insulin and IGF-1 signalling: longevity, protein homoeostasis and Alzheimer's disease. Biochem. Soc. Trans. 40, 721-727.
-
(2012)
Biochem. Soc. Trans.
, vol.40
, pp. 721-727
-
-
O'Neill, C.1
Kiely, A.P.2
Coakley, M.F.3
Manning, S.4
Long-Smith, C.M.5
-
83
-
-
1542364225
-
Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro
-
Ono K, Hasegawa K, Naiki H, Yamada M (2004) Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro. J. Neurosci. Res. 75, 742-750.
-
(2004)
J. Neurosci. Res.
, vol.75
, pp. 742-750
-
-
Ono, K.1
Hasegawa, K.2
Naiki, H.3
Yamada, M.4
-
84
-
-
84880003797
-
Vegetarian dietary patterns and mortality in Adventist Health Study 2
-
Orlich MJ, Singh PN, Sabaté J, Jaceldo-Siegl K, Fan J, Knutsen S, Beeson WL, Fraser GE (2013) Vegetarian dietary patterns and mortality in Adventist Health Study 2. JAMA Intern. Med. 173, 1230-1238.
-
(2013)
JAMA Intern. Med.
, vol.173
, pp. 1230-1238
-
-
Orlich, M.J.1
Singh, P.N.2
Sabaté, J.3
Jaceldo-Siegl, K.4
Fan, J.5
Knutsen, S.6
Beeson, W.L.7
Fraser, G.E.8
-
85
-
-
84859717284
-
Red meat consumption and mortality: results from 2 prospective cohort studies
-
Pan A, Sun Q, Bernstein AM, Schulze MB, Manson JE, Stampfer MJ, Willett WC, Hu FB (2012) Red meat consumption and mortality: results from 2 prospective cohort studies. Arch. Intern. Med. 172, 555-563.
-
(2012)
Arch. Intern. Med.
, vol.172
, pp. 555-563
-
-
Pan, A.1
Sun, Q.2
Bernstein, A.M.3
Schulze, M.B.4
Manson, J.E.5
Stampfer, M.J.6
Willett, W.C.7
Hu, F.B.8
-
86
-
-
84878910100
-
Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model
-
Parrella E, Maxim T, Maialetti F, Zhang L, Wan J, Wei M, Cohen P, Fontana L, Longo VD (2013) Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model. Aging Cell 12, 257-268.
-
(2013)
Aging Cell
, vol.12
, pp. 257-268
-
-
Parrella, E.1
Maxim, T.2
Maialetti, F.3
Zhang, L.4
Wan, J.5
Wei, M.6
Cohen, P.7
Fontana, L.8
Longo, V.D.9
-
87
-
-
84871694941
-
Diet and healthy aging
-
Partridge L (2012) Diet and healthy aging. N. Engl. J. Med. 367, 2550-2551.
-
(2012)
N. Engl. J. Med.
, vol.367
, pp. 2550-2551
-
-
Partridge, L.1
-
88
-
-
36048939348
-
Benchmarks for ageing studies
-
Partridge L, Gems D (2007) Benchmarks for ageing studies. Nature 450, 165-167.
-
(2007)
Nature
, vol.450
, pp. 165-167
-
-
Partridge, L.1
Gems, D.2
-
89
-
-
67651151249
-
Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity
-
Pawlikowska L, Hu D, Huntsman S, Sung A, Chu C, Chen J, Joyner AH, Schork NJ, Hsueh W-C, Reiner AP, Psaty BM, Atzmon G, Barzilai N, Cummings SR, Browner WS, Kwok P-Y, Ziv E (2009) Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity. Aging Cell 8, 460-472.
-
(2009)
Aging Cell
, vol.8
, pp. 460-472
-
-
Pawlikowska, L.1
Hu, D.2
Huntsman, S.3
Sung, A.4
Chu, C.5
Chen, J.6
Joyner, A.H.7
Schork, N.J.8
Hsueh, W.-C.9
Reiner, A.P.10
Psaty, B.M.11
Atzmon, G.12
Barzilai, N.13
Cummings, S.R.14
Browner, W.S.15
Kwok, P.-Y.16
Ziv, E.17
-
90
-
-
84894454891
-
Health effects of protein intake in healthy elderly populations: a systematic literature review
-
Pedersen AN, Cederholm T (2014) Health effects of protein intake in healthy elderly populations: a systematic literature review. Food Nutr. Res. 58 http://dx.doi.org/10.3402/fnr.v58.23364.
-
(2014)
Food Nutr. Res.
, vol.58
-
-
Pedersen, A.N.1
Cederholm, T.2
-
91
-
-
84860477354
-
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function
-
Price NL, Gomes AP, Ling AJY, Duarte FV, Martin-Montalvo A, North BJ, Agarwal B, Ye L, Ramadori G, Teodoro JS, Hubbard BP, Varela AT, Davis JG, Varamini B, Hafner A, Moaddel R, Rolo AP, Coppari R, Palmeira CM, de Cabo R, Baur JA, Sinclair DA (2012) SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function. Cell Metab. 15, 675-690.
-
(2012)
Cell Metab.
, vol.15
, pp. 675-690
-
-
Price, N.L.1
Gomes, A.P.2
Ling, A.J.Y.3
Duarte, F.V.4
Martin-Montalvo, A.5
North, B.J.6
Agarwal, B.7
Ye, L.8
Ramadori, G.9
Teodoro, J.S.10
Hubbard, B.P.11
Varela, A.T.12
Davis, J.G.13
Varamini, B.14
Hafner, A.15
Moaddel, R.16
Rolo, A.P.17
Coppari, R.18
Palmeira, C.M.19
de Cabo, R.20
Baur, J.A.21
Sinclair, D.A.22
more..
-
92
-
-
46149107882
-
Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy
-
Raffaghello L, Lee C, Safdie FM, Wei M, Madia F, Bianchi G, Longo VD (2008) Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy. Proc. Natl Acad. Sci. USA 105, 8215-8220.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 8215-8220
-
-
Raffaghello, L.1
Lee, C.2
Safdie, F.M.3
Wei, M.4
Madia, F.5
Bianchi, G.6
Longo, V.D.7
-
93
-
-
33846024055
-
Caffeine targets TOR complex I and provides evidence for a regulatory link between the FRB and kinase domains of Tor1p
-
Reinke A, Chen JC-Y, Aronova S, Powers T (2006) Caffeine targets TOR complex I and provides evidence for a regulatory link between the FRB and kinase domains of Tor1p. J. Biol. Chem. 281, 31616-31626.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 31616-31626
-
-
Reinke, A.1
Chen, J.-Y.2
Aronova, S.3
Powers, T.4
-
94
-
-
0028557442
-
Methionine restriction increases blood glutathione and longevity in F344 rats
-
Richie JP, Leutzinger Y, Parthasarathy S, Malloy V, Orentreich N, Zimmerman JA (1994) Methionine restriction increases blood glutathione and longevity in F344 rats. FASEB J. 8, 1302-1307.
-
(1994)
FASEB J.
, vol.8
, pp. 1302-1307
-
-
Richie, J.P.1
Leutzinger, Y.2
Parthasarathy, S.3
Malloy, V.4
Orentreich, N.5
Zimmerman, J.A.6
-
95
-
-
84874590719
-
Meat consumption and mortality - results from the European prospective investigation into cancer and nutrition
-
Rohrmann S, Overvad K, Bueno-de-Mesquita HB, Jakobsen MU, Egeberg R, Tjonneland A, Nailler L, Boutron-Ruault M-C, Clavel-Chapelon F, Krogh V, Palli D, Panico S, Tumino R, Ricceri F, Bergmann MM, Boeing H, Li K, Kaaks R, Khaw K-T, Wareham NJ, Crowe FL, Key TJ, Naska A, Trichopoulou A, Trichopoulos D, Leenders M, Peeters PH, Engeset D, Parr CL, Skeie G, Jakszyn P, Sanchez M-J, Huerta JM, Redondo ML, Barricarte A, Amiano P, Drake I, Sonestedt E, Hallmans G, Johansson I, Fedirko V, Romieux I, Ferrari P, Norat T, Vergnau AC, Riboli E, Linseisen J (2013) Meat consumption and mortality - results from the European prospective investigation into cancer and nutrition. BMC Med. 11, 63.
-
(2013)
BMC Med.
, vol.11
, pp. 63
-
-
Rohrmann, S.1
Overvad, K.2
Bueno-de-Mesquita, H.B.3
Jakobsen, M.U.4
Egeberg, R.5
Tjonneland, A.6
Nailler, L.7
Boutron-Ruault, M.-C.8
Clavel-Chapelon, F.9
Krogh, V.10
Palli, D.11
Panico, S.12
Tumino, R.13
Ricceri, F.14
Bergmann, M.M.15
Boeing, H.16
Li, K.17
Kaaks, R.18
Khaw, K.-T.19
Wareham, N.J.20
Crowe, F.L.21
Key, T.J.22
Naska, A.23
Trichopoulou, A.24
Trichopoulos, D.25
Leenders, M.26
Peeters, P.H.27
Engeset, D.28
Parr, C.L.29
Skeie, G.30
Jakszyn, P.31
Sanchez, M.-J.32
Huerta, J.M.33
Redondo, M.L.34
Barricarte, A.35
Amiano, P.36
Drake, I.37
Sonestedt, E.38
Hallmans, G.39
Johansson, I.40
Fedirko, V.41
Romieux, I.42
Ferrari, P.43
Norat, T.44
Vergnau, A.C.45
Riboli, E.46
Linseisen, J.47
more..
-
96
-
-
0000062739
-
Length of life and nutrition in the rat
-
Ross M (1961) Length of life and nutrition in the rat. J. Nutr. 75, 197-210.
-
(1961)
J. Nutr.
, vol.75
, pp. 197-210
-
-
Ross, M.1
-
97
-
-
0016824817
-
Food preference and length of life
-
Ross M, Bras G (1975) Food preference and length of life. Science 190, 165-167.
-
(1975)
Science
, vol.190
, pp. 165-167
-
-
Ross, M.1
Bras, G.2
-
98
-
-
0030978244
-
Dietary fiber, glycemic load, and risk of NIDDM in men
-
Salmerón J, Ascherio A, Rimm EB, Colditz GA, Spiegelman D, Jenkins DJ, Stampfer MJ, Wing AL, Willett WC (1997) Dietary fiber, glycemic load, and risk of NIDDM in men. Diabetes Care 20, 545-550.
-
(1997)
Diabetes Care
, vol.20
, pp. 545-550
-
-
Salmerón, J.1
Ascherio, A.2
Rimm, E.B.3
Colditz, G.A.4
Spiegelman, D.5
Jenkins, D.J.6
Stampfer, M.J.7
Wing, A.L.8
Willett, W.C.9
-
99
-
-
40449142493
-
Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice
-
Selman C, Lingard S, Choudhury AI, Batterham RL, Claret M, Clements M, Ramadani F, Okkenhaug K, Schuster E, Blanc E, Piper MD, Al-Qassab H, Speakman JR, Carmignac D, Robinson ICA, Thornton JM, Gems D, Partridge L, Withers DJ (2008) Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice. FASEB J. 22, 807-818.
-
(2008)
FASEB J.
, vol.22
, pp. 807-818
-
-
Selman, C.1
Lingard, S.2
Choudhury, A.I.3
Batterham, R.L.4
Claret, M.5
Clements, M.6
Ramadani, F.7
Okkenhaug, K.8
Schuster, E.9
Blanc, E.10
Piper, M.D.11
Al-Qassab, H.12
Speakman, J.R.13
Carmignac, D.14
Robinson, I.C.A.15
Thornton, J.M.16
Gems, D.17
Partridge, L.18
Withers, D.J.19
-
100
-
-
4544343980
-
Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies
-
Shah OJ, Wang Z, Hunter T (2004) Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies. Curr. Biol. 14, 1650-1656.
-
(2004)
Curr. Biol.
, vol.14
, pp. 1650-1656
-
-
Shah, O.J.1
Wang, Z.2
Hunter, T.3
-
101
-
-
84878129333
-
Dietary glycemic load and glycemic index and risk of cerebrovascular disease in the EPICOR cohort
-
Sieri S, Brighenti F, Agnoli C, Grioni S, Masala G, Bendinelli B, Sacerdote C, Ricceri F, Tumino R, Giurdanella MC, Pala V, Berrino F, Mattiello A, Chiodini P, Panico S, Krogh V (2013) Dietary glycemic load and glycemic index and risk of cerebrovascular disease in the EPICOR cohort. PLoS ONE 8, e62625.
-
(2013)
PLoS ONE
, vol.8
, pp. e62625
-
-
Sieri, S.1
Brighenti, F.2
Agnoli, C.3
Grioni, S.4
Masala, G.5
Bendinelli, B.6
Sacerdote, C.7
Ricceri, F.8
Tumino, R.9
Giurdanella, M.C.10
Pala, V.11
Berrino, F.12
Mattiello, A.13
Chiodini, P.14
Panico, S.15
Krogh, V.16
-
102
-
-
0035135246
-
Advanced glycation end-products: a review
-
Singh R, Barden A, Mori T, Beilin L (2001) Advanced glycation end-products: a review. Diabetologia 44, 129-146.
-
(2001)
Diabetologia
, vol.44
, pp. 129-146
-
-
Singh, R.1
Barden, A.2
Mori, T.3
Beilin, L.4
-
103
-
-
84895765028
-
The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice
-
Solon-Biet SM, McMahon AC, Ballard JWO, Ruohonen K, Wu LE, Cogger VC, Warren A, Huang X, Pichaud N, Melvin RG, Gokarn R, Khalil M, Turner N, Cooney GJ, Sinclair DA, Raubenheimer D, Le Couteur DG, Simpson SJ (2014) The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice. Cell Metab. 19, 418-430.
-
(2014)
Cell Metab.
, vol.19
, pp. 418-430
-
-
Solon-Biet, S.M.1
McMahon, A.C.2
Ballard, J.W.O.3
Ruohonen, K.4
Wu, L.E.5
Cogger, V.C.6
Warren, A.7
Huang, X.8
Pichaud, N.9
Melvin, R.G.10
Gokarn, R.11
Khalil, M.12
Turner, N.13
Cooney, G.J.14
Sinclair, D.A.15
Raubenheimer, D.16
Le Couteur, D.G.17
Simpson, S.J.18
-
104
-
-
79953221503
-
Congenital IGF1 deficiency tends to confer protection against post-natal development of malignancies
-
Steuerman R, Shevah O, Laron Z (2011) Congenital IGF1 deficiency tends to confer protection against post-natal development of malignancies. Eur. J. Endocrinol. 164, 485-489.
-
(2011)
Eur. J. Endocrinol.
, vol.164
, pp. 485-489
-
-
Steuerman, R.1
Shevah, O.2
Laron, Z.3
-
105
-
-
84905705301
-
Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice
-
Stout MB, Tchkonia T, Pirtskhalava T, Palmer AK, List EO, Berryman DE, Lubbers ER, Escande C, Spong A, Masternak MM, Oberg AL, LeBrasseur NK, Miller RA, Kopchick JJ, Bartke A, Kirkland JL (2014) Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice. Aging 6, 575-586.
-
(2014)
Aging
, vol.6
, pp. 575-586
-
-
Stout, M.B.1
Tchkonia, T.2
Pirtskhalava, T.3
Palmer, A.K.4
List, E.O.5
Berryman, D.E.6
Lubbers, E.R.7
Escande, C.8
Spong, A.9
Masternak, M.M.10
Oberg, A.L.11
LeBrasseur, N.K.12
Miller, R.A.13
Kopchick, J.J.14
Bartke, A.15
Kirkland, J.L.16
-
106
-
-
42149141146
-
Functionally significant insulin-like growth factor I receptor mutations in centenarians
-
Suh Y, Atzmon G, Cho M-O, Hwang D, Liu B, Leahy DJ, Barzilai N, Cohen P (2008) Functionally significant insulin-like growth factor I receptor mutations in centenarians. Proc. Natl Acad. Sci. USA 105, 3438-3442.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 3438-3442
-
-
Suh, Y.1
Atzmon, G.2
Cho, M.-O.3
Hwang, D.4
Liu, B.5
Leahy, D.J.6
Barzilai, N.7
Cohen, P.8
-
107
-
-
34547097247
-
Brain IRS2 signaling coordinates life span and nutrient homeostasis
-
Taguchi A, Wartschow LM, White MF (2007) Brain IRS2 signaling coordinates life span and nutrient homeostasis. Science 317, 369-372.
-
(2007)
Science
, vol.317
, pp. 369-372
-
-
Taguchi, A.1
Wartschow, L.M.2
White, M.F.3
-
108
-
-
78349299099
-
Fat tissue, aging, and cellular senescence
-
Tchkonia T, Morbeck DE, Von Zglinicki T, Van Deursen J, Lustgarten J, Scrable H, Khosla S, Jensen MD, Kirkland JL (2010) Fat tissue, aging, and cellular senescence. Aging Cell 9, 667-684.
-
(2010)
Aging Cell
, vol.9
, pp. 667-684
-
-
Tchkonia, T.1
Morbeck, D.E.2
Von Zglinicki, T.3
Van Deursen, J.4
Lustgarten, J.5
Scrable, H.6
Khosla, S.7
Jensen, M.D.8
Kirkland, J.L.9
-
109
-
-
37849045708
-
Low glycaemic index or low glycaemic load diets for overweight and obesity
-
Thomas DE, Elliott EJ, Baur L (2007) Low glycaemic index or low glycaemic load diets for overweight and obesity. Cochrane Database Syst. Rev., CD005105.
-
(2007)
Cochrane Database Syst. Rev.
, pp. CD005105
-
-
Thomas, D.E.1
Elliott, E.J.2
Baur, L.3
-
110
-
-
24144446404
-
Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability
-
Tremblay F, Krebs M, Dombrowski L, Brehm A, Bernroider E, Roth E, Nowotny P, Waldhäusl W, Marette A, Roden M (2005) Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability. Diabetes 54, 2674-2684.
-
(2005)
Diabetes
, vol.54
, pp. 2674-2684
-
-
Tremblay, F.1
Krebs, M.2
Dombrowski, L.3
Brehm, A.4
Bernroider, E.5
Roth, E.6
Nowotny, P.7
Waldhäusl, W.8
Marette, A.9
Roden, M.10
-
111
-
-
35348832340
-
Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance
-
Tremblay F, Brûlé S, Hee Um S, Li Y, Masuda K, Roden M, Sun XJ, Krebs M, Polakiewicz RD, Thomas G, Marette A (2007) Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance. Proc. Natl Acad. Sci. USA 104, 14056-14061.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 14056-14061
-
-
Tremblay, F.1
Brûlé, S.2
Hee Um, S.3
Li, Y.4
Masuda, K.5
Roden, M.6
Sun, X.J.7
Krebs, M.8
Polakiewicz, R.D.9
Thomas, G.10
Marette, A.11
-
112
-
-
38349014710
-
Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease
-
Trinh K, Moore K, Wes PD, Muchowski PJ, Dey J, Andrews L, Pallanck LJ (2008) Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease. J. Neurosci. 28, 465-472.
-
(2008)
J. Neurosci.
, vol.28
, pp. 465-472
-
-
Trinh, K.1
Moore, K.2
Wes, P.D.3
Muchowski, P.J.4
Dey, J.5
Andrews, L.6
Pallanck, L.J.7
-
113
-
-
33744505375
-
Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1
-
Um SH, D'Alessio D, Thomas G (2006) Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1. Cell Metab. 3, 393-402.
-
(2006)
Cell Metab.
, vol.3
, pp. 393-402
-
-
Um, S.H.1
D'Alessio, D.2
Thomas, G.3
-
114
-
-
79952440161
-
Epigallocatechin gallate (EGCG), a major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor
-
Van Aller GS, Carson JD, Tang W, Peng H, Zhao L, Copeland RA, Tummino PJ, Luo L (2011) Epigallocatechin gallate (EGCG), a major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor. Biochem. Biophys. Res. Commun. 406, 194-199.
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.406
, pp. 194-199
-
-
Van Aller, G.S.1
Carson, J.D.2
Tang, W.3
Peng, H.4
Zhao, L.5
Copeland, R.A.6
Tummino, P.J.7
Luo, L.8
-
115
-
-
70350627192
-
Short-term modified alternate-day fasting: a novel dietary strategy for weight loss and cardioprotection in obese adults
-
Varady KA, Bhutani S, Church EC, Klempel MC (2009) Short-term modified alternate-day fasting: a novel dietary strategy for weight loss and cardioprotection in obese adults. Am. J. Clin. Nutr. 90, 1138-1143.
-
(2009)
Am. J. Clin. Nutr.
, vol.90
, pp. 1138-1143
-
-
Varady, K.A.1
Bhutani, S.2
Church, E.C.3
Klempel, M.C.4
-
116
-
-
0642367846
-
Genetics: influence of TOR kinase on lifespan in C. elegans
-
Vellai T, Takacs-Vellai K, Zhang Y, Kovacs AL, Orosz L, Müller F (2003) Genetics: influence of TOR kinase on lifespan in C. elegans. Nature 426, 620.
-
(2003)
Nature
, vol.426
, pp. 620
-
-
Vellai, T.1
Takacs-Vellai, K.2
Zhang, Y.3
Kovacs, A.L.4
Orosz, L.5
Müller, F.6
-
117
-
-
36549030248
-
Prospective study of dietary carbohydrates, glycemic index, glycemic load, and incidence of type 2 diabetes mellitus in middle-aged Chinese women
-
Villegas R, Liu S, Gao Y-T, Yang G, Li H, Zheng W, Shu XO (2007) Prospective study of dietary carbohydrates, glycemic index, glycemic load, and incidence of type 2 diabetes mellitus in middle-aged Chinese women. Arch. Intern. Med. 167, 2310-2316.
-
(2007)
Arch. Intern. Med.
, vol.167
, pp. 2310-2316
-
-
Villegas, R.1
Liu, S.2
Gao, Y.-T.3
Yang, G.4
Li, H.5
Zheng, W.6
Shu, X.O.7
-
118
-
-
0028363366
-
Advanced glycation end products contribute to amyloidosis in Alzheimer disease
-
Vitek MP, Bhattacharya K, Glendening JM, Stopa E, Vlassara H, Bucala R, Manogue K, Cerami A (1994) Advanced glycation end products contribute to amyloidosis in Alzheimer disease. Proc. Natl Acad. Sci. USA 91, 4766-4770.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 4766-4770
-
-
Vitek, M.P.1
Bhattacharya, K.2
Glendening, J.M.3
Stopa, E.4
Vlassara, H.5
Bucala, R.6
Manogue, K.7
Cerami, A.8
-
119
-
-
45149108690
-
Caffeine extends yeast lifespan by targeting TORC1
-
Wanke V, Cameroni E, Uotila A, Piccolis M, Urban J, Loewith R, De Virgilio C (2008) Caffeine extends yeast lifespan by targeting TORC1. Mol. Microbiol. 69, 277-285.
-
(2008)
Mol. Microbiol.
, vol.69
, pp. 277-285
-
-
Wanke, V.1
Cameroni, E.2
Uotila, A.3
Piccolis, M.4
Urban, J.5
Loewith, R.6
De Virgilio, C.7
-
120
-
-
33746633037
-
Caloric restriction and human longevity: what can we learn from the Okinawans?
-
Willcox DC, Willcox BJ, Todoriki H, Curb JD, Suzuki M (2006) Caloric restriction and human longevity: what can we learn from the Okinawans? Biogerontology 7, 173-177.
-
(2006)
Biogerontology
, vol.7
, pp. 173-177
-
-
Willcox, D.C.1
Willcox, B.J.2
Todoriki, H.3
Curb, J.D.4
Suzuki, M.5
-
121
-
-
35948936851
-
Caloric restriction, the traditional Okinawan diet, and healthy aging: the diet of the world's longest-lived people and its potential impact on morbidity and life span
-
Willcox BJ, Willcox DC, Todoriki H, Fujiyoshi A, Yano K, He Q, Curb JD, Suzuki M (2007) Caloric restriction, the traditional Okinawan diet, and healthy aging: the diet of the world's longest-lived people and its potential impact on morbidity and life span. Ann. N. Y. Acad. Sci. 1114, 434-455.
-
(2007)
Ann. N. Y. Acad. Sci.
, vol.1114
, pp. 434-455
-
-
Willcox, B.J.1
Willcox, D.C.2
Todoriki, H.3
Fujiyoshi, A.4
Yano, K.5
He, Q.6
Curb, J.D.7
Suzuki, M.8
-
122
-
-
84873034262
-
Proteotoxicity and cardiac dysfunction-Alzheimer's disease of the heart?
-
Willis MS, Patterson C (2013) Proteotoxicity and cardiac dysfunction-Alzheimer's disease of the heart? N. Engl. J. Med. 368, 455-464.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 455-464
-
-
Willis, M.S.1
Patterson, C.2
-
123
-
-
0032792665
-
AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes
-
Winder WW, Hardie DG (1999) AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes. Am. J. Physiol. 277, E1-E10.
-
(1999)
Am. J. Physiol.
, vol.277
, pp. E1-E10
-
-
Winder, W.W.1
Hardie, D.G.2
-
124
-
-
84884150826
-
Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression
-
Wu JJ, Liu J, Chen EB, Wang JJ, Cao L, Narayan N, Fergusson MM, Rovira II, Allen M, Springer DA, Lago CU, Zhang S, DuBois W, Ward T, de Cabo R, Gavrilova O, Mock B, Finkel T (2013) Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression. Cell Rep. 4, 913-920.
-
(2013)
Cell Rep.
, vol.4
, pp. 913-920
-
-
Wu, J.J.1
Liu, J.2
Chen, E.B.3
Wang, J.J.4
Cao, L.5
Narayan, N.6
Fergusson, M.M.7
Rovira, I.I.8
Allen, M.9
Springer, D.A.10
Lago, C.U.11
Zhang, S.12
DuBois, W.13
Ward, T.14
de Cabo, R.15
Gavrilova, O.16
Mock, B.17
Finkel, T.18
-
125
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger S, Loewith R, Hall MN (2006) TOR signaling in growth and metabolism. Cell 124, 471-484.
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
126
-
-
20044370990
-
Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo
-
Yang F, Lim GP, Begum AN, Ubeda OJ, Simmons MR, Ambegaokar SS, Chen PP, Kayed R, Glabe CG, Frautschy SA, Cole GM (2005) Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo. J. Biol. Chem. 280, 5892-5901.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 5892-5901
-
-
Yang, F.1
Lim, G.P.2
Begum, A.N.3
Ubeda, O.J.4
Simmons, M.R.5
Ambegaokar, S.S.6
Chen, P.P.7
Kayed, R.8
Glabe, C.G.9
Frautschy, S.A.10
Cole, G.M.11
-
127
-
-
0022381249
-
Nutritional influences on aging of Fischer 344 rats: I. Physical, metabolic, and longevity characteristics
-
Yu BP, Masoro EJ, McMahan CA (1985) Nutritional influences on aging of Fischer 344 rats: I. Physical, metabolic, and longevity characteristics. J. Gerontol. 40, 657-670.
-
(1985)
J. Gerontol.
, vol.40
, pp. 657-670
-
-
Yu, B.P.1
Masoro, E.J.2
McMahan, C.A.3
|