Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: Cues for an evolutionarily conserved mechanism of life span control

Journal of Clinical Endocrinology and Metabolism

Volumn 88, Issue 7, 2003, Pages 3299-3304

  Bonafè, Massimiliano ^b   Barbieri, Michelangela ^b   Marchegiani, Francesca ^c   Olivieri, Fabiola ^c   Ragno, Emilia ^b   Giampieri, Claudia ^c   Mugianesi, Elena ^c   Centurelli, Matteo ^c   Franceschi, Claudio ^a   Paolisso, Giuseppe ^b,d  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c INRCA   (Italy)

^d IV Divisione di Medicina Interna   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; INSULIN RECEPTOR SUBSTRATE 1; PHOSPHATIDYLINOSITOL 3 KINASE; SOMATOMEDIN; SOMATOMEDIN C RECEPTOR;

ADULT; AGED; ARTICLE; DNA SEQUENCE; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; GENOTYPE; HUMAN; LIFESPAN; LONGEVITY; MALE; NORMAL HUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; DNA-BINDING PROTEINS; EVOLUTION, MOLECULAR; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE FREQUENCY; GENOTYPE; HUMANS; INSULIN; INSULIN-LIKE GROWTH FACTOR I; LONGEVITY; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RECEPTOR, IGF TYPE 1; TRANSCRIPTION FACTORS;

ANIMALIA; CAENORHABDITIS; CAENORHABDITIS ELEGANS;

EID: 0038637217     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2002-021810     Document Type: Article

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