-
1
-
-
0242490056
-
Can growth hormone (GH) accelerate aging? Evidence from GH-transgenic mice
-
Bartke A. Can growth hormone (GH) accelerate aging? Evidence from GH-transgenic mice. Neuroendocrinology. 2003; 78:2100-216.
-
(2003)
Neuroendocrinology
, vol.78
, pp. 2100-2216
-
-
Bartke, A.1
-
3
-
-
0018823104
-
The effects of hypophysectomy and continuous food restriction, begun at ages 70 and 400 days, on collagen aging, proteinuria, incidence of pathology and longevity in the male rat
-
Everitt AV, Seedsman NJ and Jones F. The effects of hypophysectomy and continuous food restriction, begun at ages 70 and 400 days, on collagen aging, proteinuria, incidence of pathology and longevity in the male rat. Mech Ageing Dev. 1980; 12:161-172.
-
(1980)
Mech Ageing Dev
, vol.12
, pp. 161-172
-
-
Everitt, A.V.1
Seedsman, N.J.2
Jones, F.3
-
4
-
-
0036086818
-
Life span extension by reduction in growth hormone-insulin-like growth factor-1 axis in a transgenic rat model
-
Shimokawa I, Higami Y, Utsuyama M, Tuchiya T, Komatsu T, Chiba T and Yamaza H. Life span extension by reduction in growth hormone-insulin-like growth factor-1 axis in a transgenic rat model. Am J Pathol. 2002; 160:2259-2265.
-
(2002)
Am J Pathol
, vol.160
, pp. 2259-2265
-
-
Shimokawa, I.1
Higami, Y.2
Utsuyama, M.3
Tuchiya, T.4
Komatsu, T.5
Chiba, T.6
Yamaza, H.7
-
6
-
-
0035811073
-
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production
-
Flurkey K, Papaconstantinou J, Miller RA and Harrison DE. Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production. Proc Natl Acad Sci U S A. 2001; 98:6736-6741.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 6736-6741
-
-
Flurkey, K.1
Papaconstantinou, J.2
Miller, R.A.3
Harrison, D.E.4
-
7
-
-
0041419437
-
Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span
-
Coschigano KT, Holland AN, Riders ME, List EO, Flyvbjerg A and Kopchick JJ. Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span. Endocrinology. 2003; 144:3799-3810.
-
(2003)
Endocrinology
, vol.144
, pp. 3799-3810
-
-
Coschigano, K.T.1
Holland, A.N.2
Riders, M.E.3
List, E.O.4
Flyvbjerg, A.5
Kopchick, J.J.6
-
8
-
-
79951938474
-
Ingles S, de Cabo R, Cohen P and Longo VD. Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans
-
Guevara-Aguirre J, Balasubramanian P, Guevara-Aguirre M, Wei M, Madia F, Cheng CW, Hwang D, Martin-Montalvo A, Saavedra J, Ingles S, de Cabo R, Cohen P and Longo VD. Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans. Sci Transl Med. 2011; 3:70ra13.
-
(2011)
Sci Transl Med
, vol.3
, Issue.70
-
-
Guevara-Aguirre, J.1
Balasubramanian, P.2
Guevara-Aguirre, M.3
Wei, M.4
Madia, F.5
Cheng, C.W.6
Hwang, D.7
Martin-Montalvo, A.8
Saavedra, J.9
-
9
-
-
84905045240
-
Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity
-
epub ahead of print
-
Milman S, Atzmon G, Huffman DM, Wan J, Crandall JP, Cohen P and Barzilai N. Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity. Aging Cell. 2014; epub ahead of print.
-
(2014)
Aging Cell
-
-
Milman, S.1
Atzmon, G.2
Huffman, D.M.3
Wan, J.4
Crandall, J.P.5
Cohen, P.6
Barzilai, N.7
-
10
-
-
84878473064
-
Somatotropic signaling: tradeoffs between growth, reproductive development, and longevity
-
Bartke A, Sun LY and Longo V. Somatotropic signaling: tradeoffs between growth, reproductive development, and longevity. Physiol Rev. 2013; 93:571-598.
-
(2013)
Physiol Rev
, vol.93
, pp. 571-598
-
-
Bartke, A.1
Sun, L.Y.2
Longo, V.3
-
11
-
-
0029608970
-
The Ames dwarf gene is required for Pit-1 gene activation
-
Andersen B, Pearse RV, 2nd, Jenne K, Sornson M, Lin SC, Bartke A and Rosenfeld MG. The Ames dwarf gene is required for Pit-1 gene activation. Dev Biol. 1995; 172:495-503.
-
(1995)
Dev Biol
, vol.172
, pp. 495-503
-
-
Andersen, B.1
Pearse II, R.V.2
Jenne, K.3
Sornson, M.4
Lin, S.C.5
Bartke, A.6
Rosenfeld, M.G.7
-
12
-
-
0025014024
-
Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1
-
Li S, Crenshaw EB, 3rd, Rawson EJ, Simmons DM, Swanson LW and Rosenfeld MG. Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1. Nature. 1990; 347:528-533.
-
(1990)
Nature
, vol.347
, pp. 528-533
-
-
Li, S.1
Crenshaw III, E.B.2
Rawson, E.J.3
Simmons, D.M.4
Swanson, L.W.5
Rosenfeld, M.G.6
-
13
-
-
84879117381
-
The GH/IGF-1 axis in ageing and longevity
-
Junnila RK, List EO, Berryman DE, Murrey JW and Kopchick JJ. The GH/IGF-1 axis in ageing and longevity. Nat Rev Endocrinol. 2013; 9:366-376.
-
(2013)
Nat Rev Endocrinol
, vol.9
, pp. 366-376
-
-
Junnila, R.K.1
List, E.O.2
Berryman, D.E.3
Murrey, J.W.4
Kopchick, J.J.5
-
14
-
-
79958243025
-
Endocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouse
-
List EO, Sackmann-Sala L, Berryman DE, Funk K, Kelder B, Gosney ES, Okada S, Ding J, Cruz-Topete D and Kopchick JJ. Endocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouse. Endocr Rev. 2011; 32:356-386.
-
(2011)
Endocr Rev
, vol.32
, pp. 356-386
-
-
List, E.O.1
Sackmann-Sala, L.2
Berryman, D.E.3
Funk, K.4
Kelder, B.5
Gosney, E.S.6
Okada, S.7
Ding, J.8
Cruz-Topete, D.9
Kopchick, J.J.10
-
15
-
-
62749144043
-
Age-related changes in body composition of bovine growth hormone transgenic mice
-
Palmer AJ, Chung MY, List EO, Walker J, Okada S, Kopchick JJ and Berryman DE. Age-related changes in body composition of bovine growth hormone transgenic mice. Endocrinology. 2009; 150:1353-1360.
-
(2009)
Endocrinology
, vol.150
, pp. 1353-1360
-
-
Palmer, A.J.1
Chung, M.Y.2
List, E.O.3
Walker, J.4
Okada, S.5
Kopchick, J.J.6
Berryman, D.E.7
-
16
-
-
32644435114
-
Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice
-
Baker DJ, Jeganathan KB, Malureanu L, Perez-Terzic C, Terzic A and van Deursen JM. Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice. J Cell Biol. 2006; 172:529-540.
-
(2006)
J Cell Biol
, vol.172
, pp. 529-540
-
-
Baker, D.J.1
Jeganathan, K.B.2
Malureanu, L.3
Perez-Terzic, C.4
Terzic, A.5
Van Deursen, J.M.6
-
17
-
-
0035347211
-
Contribution of abdominal adiposity to age-related differences in insulin sensitivity and plasma lipids in healthy nonobese women
-
DeNino WF, Tchernof A, Dionne IJ, Toth MJ, Ades PA, Sites CK and Poehlman ET. Contribution of abdominal adiposity to age-related differences in insulin sensitivity and plasma lipids in healthy nonobese women. Diabetes Care. 2001; 24:925-932.
-
(2001)
Diabetes Care
, vol.24
, pp. 925-932
-
-
DeNino, W.F.1
Tchernof, A.2
Dionne, I.J.3
Toth, M.J.4
Ades, P.A.5
Sites, C.K.6
Poehlman, E.T.7
-
18
-
-
4344602911
-
Anthropometric assessment of 10-y changes in body composition in the elderly
-
Hughes VA, Roubenoff R, Wood M, Frontera WR, Evans WJ and Fiatarone Singh MA. Anthropometric assessment of 10-y changes in body composition in the elderly. Am J Clin Nutr. 2004; 80:475-482.
-
(2004)
Am J Clin Nutr
, vol.80
, pp. 475-482
-
-
Hughes, V.A.1
Roubenoff, R.2
Wood, M.3
Frontera, W.R.4
Evans, W.J.5
Fiatarone Singh, M.A.6
-
19
-
-
0020629370
-
Influence of anatomic site and age on the replication and differentiation of rat adipocyte precursors in culture
-
Djian P, Roncari AK and Hollenberg CH. Influence of anatomic site and age on the replication and differentiation of rat adipocyte precursors in culture. J Clin Invest. 1983; 72:1200- 1208.
-
(1983)
J Clin Invest
, vol.72
, pp. 1200-1208
-
-
Djian, P.1
Roncari, A.K.2
Hollenberg, C.H.3
-
20
-
-
0032233184
-
Inhibitors of preadipocyte replication: opportunities for the treatment of obesity
-
Kirkland JL and Hollenberg CH. Inhibitors of preadipocyte replication: opportunities for the treatment of obesity. Prog Mol Subcell Biol. 1998; 20:177-195.
-
(1998)
Prog Mol Subcell Biol
, vol.20
, pp. 177-195
-
-
Kirkland, J.L.1
Hollenberg, C.H.2
-
21
-
-
0025246162
-
Age, anatomic site, and the replication and differentiation of adipocyte precursors
-
Kirkland JL, Hollenberg CH and Gillon WS. Age, anatomic site, and the replication and differentiation of adipocyte precursors. Am J Physiol. 1990; 258:C206-210.
-
(1990)
Am J Physiol
, vol.258
-
-
Kirkland, J.L.1
Hollenberg, C.H.2
Gillon, W.S.3
-
22
-
-
42549164595
-
Regional anatomic and age effects on cell function of human adipose-derived stem cells
-
Schipper BM, Marra KG, Zhang W, Donnenberg AD and Rubin JP. Regional anatomic and age effects on cell function of human adipose-derived stem cells. Ann Plast Surg. 2008; 60:538-544.
-
(2008)
Ann Plast Surg
, vol.60
, pp. 538-544
-
-
Schipper, B.M.1
Marra, K.G.2
Zhang, W.3
Donnenberg, A.D.4
Rubin, J.P.5
-
23
-
-
0034972714
-
Altered expression of C/EBP family members results in decreased adipogenesis with aging
-
Karagiannides I, Tchkonia T, Dobson DE, Steppan CM, Cummins P, Chan G, Salvatori K, Hadzopoulou-Cladaras M and Kirkland JL. Altered expression of C/EBP family members results in decreased adipogenesis with aging. Am J Physiol Regul Integr Comp Physiol. 2001; 280:R1772-1780.
-
(2001)
Am J Physiol Regul Integr Comp Physiol
, vol.280
-
-
Karagiannides, I.1
Tchkonia, T.2
Dobson, D.E.3
Steppan, C.M.4
Cummins, P.5
Chan, G.6
Salvatori, K.7
Hadzopoulou-Cladaras, M.8
Kirkland, J.L.9
-
24
-
-
33747338275
-
Increased CUG triplet repeatbinding protein-1 predisposes to impaired adipogenesis with aging
-
Karagiannides I, Thomou T, Tchkonia T, Pirtskhalava T, Kypreos KE, Cartwright A, Dalagiorgou G, Lash TL, Farmer SR, Timchenko NA and Kirkland JL. Increased CUG triplet repeatbinding protein-1 predisposes to impaired adipogenesis with aging. J Biol Chem. 2006; 281:23025-23033.
-
(2006)
J Biol Chem
, vol.281
, pp. 23025-23033
-
-
Karagiannides, I.1
Thomou, T.2
Tchkonia, T.3
Pirtskhalava, T.4
Kypreos, K.E.5
Cartwright, A.6
Dalagiorgou, G.7
Lash, T.L.8
Farmer, S.R.9
Timchenko, N.A.10
Kirkland, J.L.11
-
25
-
-
37149033176
-
Increased TNFalpha and CCAAT/enhancer-binding protein homologous protein with aging predispose preadipocytes to resist adipogenesis
-
Tchkonia T, Pirtskhalava T, Thomou T, Cartwright MJ, Wise B, Karagiannides I, Shpilman A, Lash TL, Becherer JD and Kirkland JL. Increased TNFalpha and CCAAT/enhancer-binding protein homologous protein with aging predispose preadipocytes to resist adipogenesis. Am J Physiol Endocrinol Metab. 2007; 293:E1810-1819.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
-
-
Tchkonia, T.1
Pirtskhalava, T.2
Thomou, T.3
Cartwright, M.J.4
Wise, B.5
Karagiannides, I.6
Shpilman, A.7
Lash, T.L.8
Becherer, J.D.9
Kirkland, J.L.10
-
27
-
-
77949525237
-
Aging, depot origin, and preadipocyte gene expression
-
Cartwright MJ, Schlauch K, Lenburg ME, Tchkonia T, Pirtskhalava T, Cartwright A, Thomou T and Kirkland JL. Aging, depot origin, and preadipocyte gene expression. J Gerontol A Biol Sci Med Sci. 2010; 65:242-251.
-
(2010)
J Gerontol A Biol Sci Med Sci
, vol.65
, pp. 242-251
-
-
Cartwright, M.J.1
Schlauch, K.2
Lenburg, M.E.3
Tchkonia, T.4
Pirtskhalava, T.5
Cartwright, A.6
Thomou, T.7
Kirkland, J.L.8
-
28
-
-
78349299099
-
Fat tissue, aging, and cellular senescence
-
Tchkonia T, Morbeck DE, Von Zglinicki T, Van Deursen J, Lustgarten J, Scrable H, Khosla S, Jensen MD and Kirkland JL. Fat tissue, aging, and cellular senescence. Aging Cell. 2010; 9:667- 684.
-
(2010)
Aging Cell
, vol.9
, pp. 667-684
-
-
Tchkonia, T.1
Morbeck, D.E.2
Von Zglinicki, T.3
Van Deursen, J.4
Lustgarten, J.5
Scrable, H.6
Khosla, S.7
Jensen, M.D.8
Kirkland, J.L.9
-
29
-
-
84891713034
-
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
-
Coppe JP, Patil CK, Rodier F, Sun Y, Munoz DP, Goldstein J, Nelson PS, Desprez PY and Campisi J. Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol. 2008; 6:2853-2868.
-
(2008)
PLoS Biol
, vol.6
, pp. 2853-2868
-
-
Coppe, J.P.1
Patil, C.K.2
Rodier, F.3
Sun, Y.4
Munoz, D.P.5
Goldstein, J.6
Nelson, P.S.7
Desprez, P.Y.8
Campisi, J.9
-
30
-
-
77952105389
-
Inflammatory networks during cellular senescence: causes and consequences
-
Freund A, Orjalo AV, Desprez PY and Campisi J. Inflammatory networks during cellular senescence: causes and consequences. Trends Mol Med. 2010; 16:238-246.
-
(2010)
Trends Mol Med
, vol.16
, pp. 238-246
-
-
Freund, A.1
Orjalo, A.V.2
Desprez, P.Y.3
Campisi, J.4
-
31
-
-
13944260728
-
Stromalepithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation
-
Parrinello S, Coppe JP, Krtolica A and Campisi J. Stromalepithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation. J Cell Sci. 2005; 118:485-496.
-
(2005)
J Cell Sci
, vol.118
, pp. 485-496
-
-
Parrinello, S.1
Coppe, J.P.2
Krtolica, A.3
Campisi, J.4
-
32
-
-
33846937033
-
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
-
Xue W, Zender L, Miething C, Dickins RA, Hernando E, Krizhanovsky V, Cordon-Cardo C and Lowe SW. Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature. 2007; 445:656-660.
-
(2007)
Nature
, vol.445
, pp. 656-660
-
-
Xue, W.1
Zender, L.2
Miething, C.3
Dickins, R.A.4
Hernando, E.5
Krizhanovsky, V.6
Cordon-Cardo, C.7
Lowe, S.W.8
-
33
-
-
80855138775
-
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
-
Baker DJ, Wijshake T, Tchkonia T, LeBrasseur NK, Childs BG, van de Sluis B, Kirkland JL and van Deursen JM. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature. 2011; 479:232-236.
-
(2011)
Nature
, vol.479
, pp. 232-236
-
-
Baker, D.J.1
Wijshake, T.2
Tchkonia, T.3
LeBrasseur, N.K.4
Childs, B.G.5
van de Sluis, B.6
Kirkland, J.L.7
van Deursen, J.M.8
-
35
-
-
3042815659
-
Comparing adiposity profiles in three mouse models with altered GH signaling
-
Berryman DE, List EO, Coschigano KT, Behar K, Kim JK and Kopchick JJ. Comparing adiposity profiles in three mouse models with altered GH signaling. Growth Horm IGF Res. 2004; 14:309- 318.
-
(2004)
Growth Horm IGF Res
, vol.14
, pp. 309-318
-
-
Berryman, D.E.1
List, E.O.2
Coschigano, K.T.3
Behar, K.4
Kim, J.K.5
Kopchick, J.J.6
-
36
-
-
74049103564
-
Two-year body composition analyses of long-lived GHR null mice
-
Berryman DE, List EO, Palmer AJ, Chung MY, Wright-Piekarski J, Lubbers E, O'Connor P, Okada S and Kopchick JJ. Two-year body composition analyses of long-lived GHR null mice. J Gerontol A Biol Sci Med Sci. 2010; 65:31-40.
-
(2010)
J Gerontol A Biol Sci Med Sci
, vol.65
, pp. 31-40
-
-
Berryman, D.E.1
List, E.O.2
Palmer, A.J.3
Chung, M.Y.4
Wright-Piekarski, J.5
Lubbers, E.6
O'Connor, P.7
Okada, S.8
Kopchick, J.J.9
-
37
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors
-
Campisi J. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell. 2005; 120:513-522.
-
(2005)
Cell
, vol.120
, pp. 513-522
-
-
Campisi, J.1
-
38
-
-
45449084795
-
Cellular senescence and organismal aging
-
Jeyapalan JC and Sedivy JM. Cellular senescence and organismal aging. Mech Ageing Dev. 2008; 129:467-474.
-
(2008)
Mech Ageing Dev
, vol.129
, pp. 467-474
-
-
Jeyapalan, J.C.1
Sedivy, J.M.2
-
39
-
-
84872047225
-
Translating advances from the basic biology of aging into clinical application
-
Kirkland JL. Translating advances from the basic biology of aging into clinical application. Exp Gerontol. 2013; 48:1-5.
-
(2013)
Exp Gerontol
, vol.48
, pp. 1-5
-
-
Kirkland, J.L.1
-
41
-
-
0032819340
-
Aging, body composition, and lifestyle: the Fels Longitudinal Study
-
Guo SS, Zeller C, Chumlea WC and Siervogel RM. Aging, body composition, and lifestyle: the Fels Longitudinal Study. Am J Clin Nutr. 1999; 70:405-411.
-
(1999)
Am J Clin Nutr
, vol.70
, pp. 405-411
-
-
Guo, S.S.1
Zeller, C.2
Chumlea, W.C.3
Siervogel, R.M.4
-
42
-
-
84877580638
-
Mechanisms and Metabolic Implications of Regional Differences among Fat Depots
-
Tchkonia T, Thomou T, Zhu Y, Karagiannides I, Pothoulakis C, Jensen MD and Kirkland JL. Mechanisms and Metabolic Implications of Regional Differences among Fat Depots. Cell Metab. 2013; 17:644-656.
-
(2013)
Cell Metab
, vol.17
, pp. 644-656
-
-
Tchkonia, T.1
Thomou, T.2
Zhu, Y.3
Karagiannides, I.4
Pothoulakis, C.5
Jensen, M.D.6
Kirkland, J.L.7
-
43
-
-
0023223134
-
Adipose tissue development: the role of precursor cells and adipogenic factors Part I: Adipose tissue development and the role of precursor cells
-
Hauner H and Loffler G. Adipose tissue development: the role of precursor cells and adipogenic factors. Part I: Adipose tissue development and the role of precursor cells. Klin Wochenschr. 1987; 65:803-811.
-
(1987)
Klin Wochenschr
, vol.65
, pp. 803-811
-
-
Hauner, H.1
Loffler, G.2
-
44
-
-
0023190448
-
Adipose tissue development: the role of precursor cells and adipogenic factors Part II: The regulation of the adipogenic conversion by hormones and serum factors
-
Loffler G and Hauner H. Adipose tissue development: the role of precursor cells and adipogenic factors. Part II: The regulation of the adipogenic conversion by hormones and serum factors. Klin Wochenschr. 1987; 65:812-817.
-
(1987)
Klin Wochenschr
, vol.65
, pp. 812-817
-
-
Loffler, G.1
Hauner, H.2
-
45
-
-
0029915556
-
Biological effects of human growth hormone in rat adipocyte precursor cells and newly differentiated adipocytes in primary culture
-
Wabitsch M, Heinze E, Hauner H, Shymko RM, Teller WM, De Meyts P and Ilondo MM. Biological effects of human growth hormone in rat adipocyte precursor cells and newly differentiated adipocytes in primary culture. Metabolism. 1996; 45:34-42.
-
(1996)
Metabolism
, vol.45
, pp. 34-42
-
-
Wabitsch, M.1
Heinze, E.2
Hauner, H.3
Shymko, R.M.4
Teller, W.M.5
De Meyts, P.6
Ilondo, M.M.7
-
46
-
-
0029391352
-
The role of growth hormone/insulin-like growth factors in adipocyte differentiation
-
Wabitsch M, Hauner H, Heinze E and Teller WM. The role of growth hormone/insulin-like growth factors in adipocyte differentiation. Metabolism. 1995; 44:45-49.
-
(1995)
Metabolism
, vol.44
, pp. 45-49
-
-
Wabitsch, M.1
Hauner, H.2
Heinze, E.3
Teller, W.M.4
-
47
-
-
0023134257
-
Development of a chemically defined serum-free medium for differentiation of rat adipose precursor cells
-
Deslex S, Negrel R and Ailhaud G. Development of a chemically defined serum-free medium for differentiation of rat adipose precursor cells. Exp Cell Res. 1987; 168:15-30.
-
(1987)
Exp Cell Res
, vol.168
, pp. 15-30
-
-
Deslex, S.1
Negrel, R.2
Ailhaud, G.3
-
48
-
-
33845325476
-
Adipocyte differentiation from the inside out
-
Rosen ED and MacDougald OA. Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol. 2006; 7:885-896.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 885-896
-
-
Rosen, E.D.1
MacDougald, O.A.2
-
49
-
-
0032977513
-
Age-related adipose tissue mRNA expression of ADD1/SREBP1, PPARgamma, lipoprotein lipase, and GLUT4 glucose transporter in rhesus monkeys
-
Hotta K, Bodkin NL, Gustafson TA, Yoshioka S, Ortmeyer HK and Hansen BC. Age-related adipose tissue mRNA expression of ADD1/SREBP1, PPARgamma, lipoprotein lipase, and GLUT4 glucose transporter in rhesus monkeys. J Gerontol A Biol Sci Med Sci. 1999; 54:B183-188.
-
(1999)
J Gerontol A Biol Sci Med Sci
, vol.54
-
-
Hotta, K.1
Bodkin, N.L.2
Gustafson, T.A.3
Yoshioka, S.4
Ortmeyer, H.K.5
Hansen, B.C.6
-
50
-
-
33751044208
-
Developmental aspects of adipose tissue in GH receptor and prolactin receptor gene disrupted mice: site-specific effects upon proliferation, differentiation and hormone sensitivity
-
Flint DJ, Binart N, Boumard S, Kopchick JJ and Kelly P. Developmental aspects of adipose tissue in GH receptor and prolactin receptor gene disrupted mice: site-specific effects upon proliferation, differentiation and hormone sensitivity. J Endocrinol. 2006; 191:101-111.
-
(2006)
J Endocrinol
, vol.191
, pp. 101-111
-
-
Flint, D.J.1
Binart, N.2
Boumard, S.3
Kopchick, J.J.4
Kelly, P.5
-
52
-
-
84862891914
-
Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging
-
Blagosklonny MV. Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging. Aging (Milano). 2012; 4:159-165.
-
(2012)
Aging (Milano)
, vol.4
, pp. 159-165
-
-
Blagosklonny, M.V.1
-
53
-
-
84894232184
-
Geriatric muscle stem cells switch reversible quiescence into senescence
-
Sousa-Victor P, Gutarra S, Garcia-Prat L, Rodriguez-Ubreva J, Ortet L, Ruiz-Bonilla V, Jardi M, Ballestar E, Gonzalez S, Serrano AL, Perdiguero E and Munoz-Canoves P. Geriatric muscle stem cells switch reversible quiescence into senescence. Nature. 2014; 506:316-321.
-
(2014)
Nature
, vol.506
, pp. 316-321
-
-
Sousa-Victor, P.1
Gutarra, S.2
Garcia-Prat, L.3
Rodriguez-Ubreva, J.4
Ortet, L.5
Ruiz-Bonilla, V.6
Jardi, M.7
Ballestar, E.8
Gonzalez, S.9
Serrano, A.L.10
Perdiguero, E.11
Munoz-Canoves, P.12
-
54
-
-
84902578762
-
Contact inhibition and high cell density deactivate the mammalian target of rapamycin pathway, thus suppressing the senescence program
-
Leontieva OV, Demidenko ZN and Blagosklonny MV. Contact inhibition and high cell density deactivate the mammalian target of rapamycin pathway, thus suppressing the senescence program. Proc Natl Acad Sci U S A. 2014; 111:8832-8837.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 8832-8837
-
-
Leontieva, O.V.1
Demidenko, Z.N.2
Blagosklonny, M.V.3
-
56
-
-
67649316033
-
Rapamycin decelerates cellular senescence
-
Demidenko ZN, Zubova SG, Bukreeva EI, Pospelov VA, Pospelova TV and Blagosklonny MV. Rapamycin decelerates cellular senescence. Cell Cycle. 2009; 8:1888-1895.
-
(2009)
Cell Cycle
, vol.8
, pp. 1888-1895
-
-
Demidenko, Z.N.1
Zubova, S.G.2
Bukreeva, E.I.3
Pospelov, V.A.4
Pospelova, T.V.5
Blagosklonny, M.V.6
-
59
-
-
84892989687
-
Rapamycin enhances long-term hematopoietic reconstitution of ex vivo expanded mouse hematopoietic stem cells by inhibiting senescence
-
Luo Y, Li L, Zou P, Wang J, Shao L, Zhou D and Liu L. Rapamycin enhances long-term hematopoietic reconstitution of ex vivo expanded mouse hematopoietic stem cells by inhibiting senescence. Transplantation. 2014; 97:20-29.
-
(2014)
Transplantation
, vol.97
, pp. 20-29
-
-
Luo, Y.1
Li, L.2
Zou, P.3
Wang, J.4
Shao, L.5
Zhou, D.6
Liu, L.7
-
60
-
-
84866054806
-
mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis
-
Iglesias-Bartolome R, Patel V, Cotrim A, Leelahavanichkul K, Molinolo AA, Mitchell JB and Gutkind JS. mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis. Cell Stem Cell. 2012; 11:401-414.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 401-414
-
-
Iglesias-Bartolome, R.1
Patel, V.2
Cotrim, A.3
Leelahavanichkul, K.4
Molinolo, A.A.5
Mitchell, J.B.6
Gutkind, J.S.7
-
61
-
-
0036038735
-
High glucose-induced replicative senescence: point of no return and effect of telomerase
-
Blazer S, Khankin E, Segev Y, Ofir R, Yalon-Hacohen M, Kra-Oz Z, Gottfried Y, Larisch S and Skorecki KL. High glucose-induced replicative senescence: point of no return and effect of telomerase. Biochem Biophys Res Commun. 2002; 296:93-101.
-
(2002)
Biochem Biophys Res Commun
, vol.296
, pp. 93-101
-
-
Blazer, S.1
Khankin, E.2
Segev, Y.3
Ofir, R.4
Yalon-Hacohen, M.5
Kra-Oz, Z.6
Gottfried, Y.7
Larisch, S.8
Skorecki, K.L.9
-
62
-
-
84865354347
-
IGF-I enhances cellular senescence via the reactive oxygen speciesp53 pathway
-
Handayaningsih AE, Takahashi M, Fukuoka H, Iguchi G, Nishizawa H, Yamamoto M, Suda K and Takahashi Y. IGF-I enhances cellular senescence via the reactive oxygen speciesp53 pathway. Biochem Biophys Res Commun. 2012; 425:478- 484.
-
(2012)
Biochem Biophys Res Commun
, vol.425
, pp. 478-484
-
-
Handayaningsih, A.E.1
Takahashi, M.2
Fukuoka, H.3
Iguchi, G.4
Nishizawa, H.5
Yamamoto, M.6
Suda, K.7
Takahashi, Y.8
-
63
-
-
84904858835
-
Insulin-like growth factor-1 regulates the SIRT1-p53 pathway in cellular senescence
-
epub ahead of print
-
Tran D, Bergholz J, Zhang H, He H, Wang Y, Zhang Y, Li Q, Kirkland JL and Xiao Z-X. Insulin-like growth factor-1 regulates the SIRT1-p53 pathway in cellular senescence. Aging Cell. 2014; epub ahead of print.
-
(2014)
Aging Cell
-
-
Tran, D.1
Bergholz, J.2
Zhang, H.3
He, H.4
Wang, Y.5
Zhang, Y.6
Li, Q.7
Kirkland, J.L.8
Xiao, Z.-X.9
-
64
-
-
79956216700
-
Dose-dependent modulatory effects of insulin on glucose-induced endothelial senescence in vitro and in vivo: a relationship between telomeres and nitric oxide
-
Matsui-Hirai H, Hayashi T, Yamamoto S, Ina K, Maeda M, Kotani H, Iguchi A, Ignarro LJ and Hattori Y. Dose-dependent modulatory effects of insulin on glucose-induced endothelial senescence in vitro and in vivo: a relationship between telomeres and nitric oxide. J Pharmacol Exp Ther. 2011; 337:591-599.
-
(2011)
J Pharmacol Exp Ther
, vol.337
, pp. 591-599
-
-
Matsui-Hirai, H.1
Hayashi, T.2
Yamamoto, S.3
Ina, K.4
Maeda, M.5
Kotani, H.6
Iguchi, A.7
Ignarro, L.J.8
Hattori, Y.9
-
65
-
-
74049114051
-
The effects of growth hormone (GH) treatment on GH and insulin/IGF-1 signaling in long-lived Ames dwarf mice
-
Masternak MM, Panici JA, Wang F, Wang Z and Spong A. The effects of growth hormone (GH) treatment on GH and insulin/IGF-1 signaling in long-lived Ames dwarf mice. J Gerontol A Biol Sci Med Sci. 2010; 65:24-30.
-
(2010)
J Gerontol A Biol Sci Med Sci
, vol.65
, pp. 24-30
-
-
Masternak, M.M.1
Panici, J.A.2
Wang, F.3
Wang, Z.4
Spong, A.5
-
66
-
-
78649719816
-
Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice
-
Panici JA, Harper JM, Miller RA, Bartke A, Spong A and Masternak MM. Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice. Faseb J. 2010; 24:5073-5079.
-
(2010)
Faseb J
, vol.24
, pp. 5073-5079
-
-
Panici, J.A.1
Harper, J.M.2
Miller, R.A.3
Bartke, A.4
Spong, A.5
Masternak, M.M.6
-
67
-
-
76649085804
-
Deleted in breast cancer-1 regulates SIRT1 activity and contributes to highfat diet-induced liver steatosis in mice
-
Escande C, Chini CC, Nin V, Dykhouse KM, Novak CM, Levine J, van Deursen J, Gores GJ, Chen J, Lou Z and Chini EN. Deleted in breast cancer-1 regulates SIRT1 activity and contributes to highfat diet-induced liver steatosis in mice. J Clin Invest. 2010; 120:545-558.
-
(2010)
J Clin Invest
, vol.120
, pp. 545-558
-
-
Escande, C.1
Chini, C.C.2
Nin, V.3
Dykhouse, K.M.4
Novak, C.M.5
Levine, J.6
van Deursen, J.7
Gores, G.J.8
Chen, J.9
Lou, Z.10
Chini, E.N.11
-
68
-
-
0029873470
-
Effects of fat depot site on differentiation-dependent gene expression in rat preadipocytes
-
Kirkland JL, Hollenberg CH and Gillon WS. Effects of fat depot site on differentiation-dependent gene expression in rat preadipocytes. Int J Obes Relat Metab Disord. 1996; 20 Suppl 3:S102-107.
-
(1996)
Int J Obes Relat Metab Disord
, vol.20
, Issue.3 SUPPL.
-
-
Kirkland, J.L.1
Hollenberg, C.H.2
Gillon, W.S.3
-
69
-
-
0024522450
-
Varying capacities for replication of rat adipocyte precursor clones and adipose tissue growth
-
Wang H, Kirkland JL and Hollenberg CH. Varying capacities for replication of rat adipocyte precursor clones and adipose tissue growth. J Clin Invest. 1989; 83:1741-1746.
-
(1989)
J Clin Invest
, vol.83
, pp. 1741-1746
-
-
Wang, H.1
Kirkland, J.L.2
Hollenberg, C.H.3
-
70
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(- Delta Delta C(T)) Method
-
Livak KJ and Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(- Delta Delta C(T)) Method. Methods. 2001; 25:402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
|