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Volumn 12, Issue 2, 2015, Pages 297-318

Polymeric micelles for oral drug administration enabling locoregional and systemic treatments

Author keywords

Drug solubilization; Efflux inhibition; Locoregional treatment; Micelle architecture; Oral administration; Polymeric micelles

Indexed keywords

COPOLYMER; POLYMER; DRUG; MICELLE;

EID: 84921490166     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2015.960841     Document Type: Review
Times cited : (98)

References (130)
  • 4
    • 84859719708 scopus 로고    scopus 로고
    • Oral drug delivery with polymeric nanoparticles: The gastrointestinal mucus barriers
    • Ensign LM, Cone R, Hanes J. Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers. Adv Drug Deliv Rev 2012;64:557-70
    • (2012) Adv Drug Deliv Rev , vol.64 , pp. 557-570
    • Ensign, L.M.1    Cone, R.2    Hanes, J.3
  • 5
    • 85028127551 scopus 로고    scopus 로고
    • Polymeric micelles and alternative nanonized delivery vehicles for poorly soluble drugs
    • Lu Y, Park K. Polymeric micelles and alternative nanonized delivery vehicles for poorly soluble drugs. Int J Pharm 2013;453:198-214
    • (2013) Int J Pharm , vol.453 , pp. 198-214
    • Lu, Y.1    Park, K.2
  • 6
    • 4644335531 scopus 로고    scopus 로고
    • Polymeric micelles for oral drug delivery: Why and how
    • Francis MF, Cristea M, Winnik FM. Polymeric micelles for oral drug delivery: why and how. Pure Appl Chem 2004;76:1321-35
    • (2004) Pure Appl Chem , vol.76 , pp. 1321-1335
    • Francis, M.F.1    Cristea, M.2    Winnik, F.M.3
  • 8
    • 84862804633 scopus 로고    scopus 로고
    • Polymeric micelles drug delivery system in oncology
    • Gong J, Chen M, Zheng Y, et al. Polymeric micelles drug delivery system in oncology. J Control Release 2012;159:312-23
    • (2012) J Control Release , vol.159 , pp. 312-323
    • Gong, J.1    Chen, M.2    Zheng, Y.3
  • 10
    • 28544450961 scopus 로고    scopus 로고
    • Block copolymer micelles: Preparation, characterization and application in drug delivery
    • Gaucher G, Dufresne MH, Sant VP, et al. Block copolymer micelles: preparation, characterization and application in drug delivery. J Control Release 2005;109:169-88
    • (2005) J Control Release , vol.109 , pp. 169-188
    • Gaucher, G.1    Dufresne, M.H.2    Sant, V.P.3
  • 13
    • 84866246051 scopus 로고    scopus 로고
    • High drug loading self-microemulsifying/ micelle formulation: Design by highthroughput formulation screening system and in vivo evaluation
    • Sakai K, Obata K, Yoshikawa M, et al. High drug loading self-microemulsifying/ micelle formulation: design by highthroughput formulation screening system and in vivo evaluation. Drug Dev Ind Pharm 2012;38:1254-61
    • (2012) Drug Dev Ind Pharm , vol.38 , pp. 1254-1261
    • Sakai, K.1    Obata, K.2    Yoshikawa, M.3
  • 14
    • 33646367645 scopus 로고    scopus 로고
    • Polyethylene glycol-phosphatidylethanolamine conjugate (PEG-PE)-based mixed micelles: Some properties, loading with paclitaxel, and modulation of P-glycoprotein-mediated efflux
    • Dabholkar RD, Sawant RM, Mongayt DA, et al. Polyethylene glycol-phosphatidylethanolamine conjugate (PEG-PE)-based mixed micelles: some properties, loading with paclitaxel, and modulation of P-glycoprotein-mediated efflux. Int J Pharm 2006;315:148-57
    • (2006) Int J Pharm , vol.315 , pp. 148-157
    • Dabholkar, R.D.1    Sawant, R.M.2    Mongayt, D.A.3
  • 15
    • 79955522520 scopus 로고    scopus 로고
    • The mechanism of enhancement on oral absorption of paclitaxel by N-octyl-Osulfate chitosan micelles
    • Mo R, Jin X, Li N, et al. The mechanism of enhancement on oral absorption of paclitaxel by N-octyl-Osulfate chitosan micelles. Biomaterials 2011;32:4609-20
    • (2011) Biomaterials , vol.32 , pp. 4609-4620
    • Mo, R.1    Jin, X.2    Li, N.3
  • 16
    • 8144225129 scopus 로고    scopus 로고
    • Self-assembly and characterization of paclitaxel-loaded N-octyl-O-sulfate chitosan micellar system
    • Zhang C, Qineng P, Zhang H. Self-assembly and characterization of paclitaxel-loaded N-octyl-O-sulfate chitosan micellar system. Colloids Surf B Biointerfaces 2004;39:69-75
    • (2004) Colloids Surf B Biointerfaces , vol.39 , pp. 69-75
    • Zhang, C.1    Qineng, P.2    Zhang, H.3
  • 17
    • 84866700931 scopus 로고    scopus 로고
    • An orally administered redox nanoparticle that accumulates in the colonic mucosa and reduces colitis in mice
    • Vong LB, Tomita T, Yoshitomi T, et al. An orally administered redox nanoparticle that accumulates in the colonic mucosa and reduces colitis in mice. Gastroenterology 2012;143:1027-36
    • (2012) Gastroenterology , vol.143 , pp. 1027-1036
    • Vong, L.B.1    Tomita, T.2    Yoshitomi, T.3
  • 18
    • 84875155754 scopus 로고    scopus 로고
    • Amphiphilic polyallylamine based polymeric micelles for siRNA delivery to the gastrointestinal tract: In vitro investigations
    • Guo J, O'Mahony AM, Cheng WP, O'Driscoll CM. Amphiphilic polyallylamine based polymeric micelles for siRNA delivery to the gastrointestinal tract: in vitro investigations. Int J Pharm 2013;447:150-7
    • (2013) Int J Pharm , vol.447 , pp. 150-157
    • Guo, J.1    O'Mahony, A.M.2    Cheng, W.P.3    O'Driscoll, C.M.4
  • 19
    • 84862731507 scopus 로고    scopus 로고
    • Enhanced oral bioavailability of paclitaxel in pluronic/LHR mixed polymeric micelles: Preparation, in vitro and in vivo evaluation
    • Dahmani FZ, Yang H, Zhou J, et al. Enhanced oral bioavailability of paclitaxel in pluronic/LHR mixed polymeric micelles: preparation, in vitro and in vivo evaluation. Eur J Pharm Sci 2012;47:179-89
    • (2012) Eur J Pharm Sci , vol.47 , pp. 179-189
    • Dahmani, F.Z.1    Yang, H.2    Zhou, J.3
  • 20
    • 50149089760 scopus 로고    scopus 로고
    • Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration
    • Ren X, Mao X, Si L, et al. Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration. Eur J Pharm Biopharm 2008;70:279-88
    • (2008) Eur J Pharm Biopharm , vol.70 , pp. 279-288
    • Ren, X.1    Mao, X.2    Si, L.3
  • 21
  • 22
    • 79951769859 scopus 로고    scopus 로고
    • The antitumor efficacy of functional paclitaxel nanomicelles in treating resistant breast cancers by oral delivery
    • Yao HJ, Ju RJ, Wang XX, et al. The antitumor efficacy of functional paclitaxel nanomicelles in treating resistant breast cancers by oral delivery. Biomaterials 2011;32:3285-302
    • (2011) Biomaterials , vol.32 , pp. 3285-3302
    • Yao, H.J.1    Ju, R.J.2    Wang, X.X.3
  • 23
    • 73649133678 scopus 로고    scopus 로고
    • Overcoming the barriers in micellar drug delivery: Loading efficiency, in vivo stability, and micelle-cell interaction
    • Kim S, Shi Y, Kim JY, et al. Overcoming the barriers in micellar drug delivery: loading efficiency, in vivo stability, and micelle-cell interaction. Expert Opin Drug Deliv 2010;7:49-62
    • (2010) Expert Opin Drug Deliv , vol.7 , pp. 49-62
    • Kim, S.1    Shi, Y.2    Kim, J.Y.3
  • 24
    • 84887941683 scopus 로고    scopus 로고
    • Temperature- and pH-sensitive polymeric micelles for drug encapsulation, release and targeting
    • Alvarez-Lorenzo C, Concheiro A, editors. Royal Society of Chemistry; London
    • Sosnik A. Temperature- and pH-sensitive polymeric micelles for drug encapsulation, release and targeting. In: Alvarez-Lorenzo C, Concheiro A, editors. Smart materials for drug delivery. Volume 1 The Royal Society of Chemistry; London: 2013. p. 115-47
    • (2013) Smart Materials for Drug Delivery , vol.1 , pp. 115-147
    • Sosnik, A.1
  • 25
    • 0142119372 scopus 로고    scopus 로고
    • Design of environmentsensitive supramolecular assemblies for intracellular drug delivery: Polymeric micelles that are responsive to intracellular pH change
    • Bae Y, Fukushima S, Harada A, Kataoka K. Design of environmentsensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change. Angew Chem Int Ed Engl 2003;42:4640-3
    • (2003) Angew Chem Int Ed Engl , vol.42 , pp. 4640-4643
    • Bae, Y.1    Fukushima, S.2    Harada, A.3    Kataoka, K.4
  • 26
    • 43449084030 scopus 로고    scopus 로고
    • Polymeric micelles in oral chemotherapy
    • Bromberg L. Polymeric micelles in oral chemotherapy. J Control Release 2008;128:99-112
    • (2008) J Control Release , vol.128 , pp. 99-112
    • Bromberg, L.1
  • 27
    • 85047286768 scopus 로고    scopus 로고
    • Polymeric micelles, a promising drug delivery system to enhance bioavailability of poorly water-soluble drugs
    • Xu W, Ling P, Zhang T. Polymeric micelles, a promising drug delivery system to enhance bioavailability of poorly water-soluble drugs. J Drug Deliv 2013;2013:340315
    • (2013) J Drug Deliv , vol.2013 , pp. 340315
    • Xu, W.1    Ling, P.2    Zhang, T.3
  • 28
    • 84891626532 scopus 로고    scopus 로고
    • Loading of polymer nanocarriers: Factors, mechanisms and applications
    • Kowalczuk A, Trzcinska R, Trzebicka B, et al. Loading of polymer nanocarriers: factors, mechanisms and applications. Prog Polym Sci 2014;39:43-86
    • (2014) Prog Polym Sci , vol.39 , pp. 43-86
    • Kowalczuk, A.1    Trzcinska, R.2    Trzebicka, B.3
  • 29
    • 80054095413 scopus 로고    scopus 로고
    • Engineering of amphiphilic block copolymers for polymeric micellar drug and gene delivery
    • Xiong XB, Falamarzian A, Garg SM, Lavasanifar A. Engineering of amphiphilic block copolymers for polymeric micellar drug and gene delivery. J Control Release 2011;155:248-61
    • (2011) J Control Release , vol.155 , pp. 248-261
    • Xiong, X.B.1    Falamarzian, A.2    Garg, S.M.3    Lavasanifar, A.4
  • 30
    • 9944229543 scopus 로고    scopus 로고
    • Targeted polymeric micelles for delivery of poorly soluble drugs
    • Torchilin VP. Targeted polymeric micelles for delivery of poorly soluble drugs. Cell Mol Life Sci 2004;61:2549-59
    • (2004) Cell Mol Life Sci , vol.61 , pp. 2549-2559
    • Torchilin, V.P.1
  • 31
    • 25844504183 scopus 로고    scopus 로고
    • Exploiting the vitamin B12 pathway to enhance oral drug delivery via polymeric micelles
    • Francis MF, Cristea M, Winnik FM. Exploiting the vitamin B12 pathway to enhance oral drug delivery via polymeric micelles. Biomacromolecules 2005;6:2462-7
    • (2005) Biomacromolecules , vol.6 , pp. 2462-2467
    • Francis, M.F.1    Cristea, M.2    Winnik, F.M.3
  • 32
    • 0034950084 scopus 로고    scopus 로고
    • Novel polymeric micelles based on the amphiphilic diblock copolymer poly(N-vinyl- 2-pyrrolidone)-block-poly(D,Llactide)
    • Benahmed A, Ranger M, Leroux JC. Novel polymeric micelles based on the amphiphilic diblock copolymer poly(N-vinyl- 2-pyrrolidone)-block-poly(D,Llactide). Pharm Res 2001;18:323-8
    • (2001) Pharm Res , vol.18 , pp. 323-328
    • Benahmed, A.1    Ranger, M.2    Leroux, J.C.3
  • 33
    • 34248577169 scopus 로고    scopus 로고
    • Poly(ethylene oxide)-poly(propylene oxide) block copolymer micelles as drug delivery agents: Improved hydrosolubility, stability and bioavailability of drugs
    • Chiappetta DA, Sosnik A. Poly(ethylene oxide)-poly(propylene oxide) block copolymer micelles as drug delivery agents: improved hydrosolubility, stability and bioavailability of drugs. Eur J Pharm Biopharm 2007;66:303-17
    • (2007) Eur J Pharm Biopharm , vol.66 , pp. 303-317
    • Chiappetta, D.A.1    Sosnik, A.2
  • 35
    • 0037072478 scopus 로고    scopus 로고
    • Pluronic® block copolymers for overcoming drug resistance in cancer
    • Kabanov AV, Batrakova EV, Alakhov VY. Pluronic® block copolymers for overcoming drug resistance in cancer. Adv Drug Deliv Rev 2002;54:759-79
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 759-779
    • Kabanov, A.V.1    Batrakova, E.V.2    Alakhov, V.Y.3
  • 36
    • 54249111320 scopus 로고    scopus 로고
    • Prevention of MDR development in leukemia cells by micelle-forming polymeric surfactant
    • Sharma AK, Zhang L, Li S, et al. Prevention of MDR development in leukemia cells by micelle-forming polymeric surfactant. J Control Release 2008;131:220-7
    • (2008) J Control Release , vol.131 , pp. 220-227
    • Sharma, A.K.1    Zhang, L.2    Li, S.3
  • 37
    • 84881328367 scopus 로고    scopus 로고
    • Cytocompatibility and P-glycoprotein inhibition of block copolymers: Structureactivity relationship
    • Cambón A, Brea J, Loza MI, et al. Cytocompatibility and P-glycoprotein inhibition of block copolymers: structureactivity relationship. Mol Pharm 2013;10:3232-41
    • (2013) Mol Pharm , vol.10 , pp. 3232-3241
    • Cambón, A.1    Brea, J.2    Loza, M.I.3
  • 38
    • 49749101644 scopus 로고    scopus 로고
    • Pluronic block copolymers: Evolution of drug delivery concept from inert nanocarriers to biological response modifiers
    • Batrakova EV, Kabanov AV. Pluronic block copolymers: evolution of drug delivery concept from inert nanocarriers to biological response modifiers. J Control Release 2008;130:98-106
    • (2008) J Control Release , vol.130 , pp. 98-106
    • Batrakova, E.V.1    Kabanov, A.V.2
  • 39
    • 76749086452 scopus 로고    scopus 로고
    • Differential metabolic responses to pluronic in MDR and non-MDR cells: A novel pathway for chemosensitization of drug resistant cancers
    • Alakhova DY, Rapoport NY, Batrakova EV, et al. Differential metabolic responses to pluronic in MDR and non-MDR cells: a novel pathway for chemosensitization of drug resistant cancers. J Control Release 2010;142:89-100
    • (2010) J Control Release , vol.142 , pp. 89-100
    • Alakhova, D.Y.1    Rapoport, N.Y.2    Batrakova, E.V.3
  • 40
    • 78650051224 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein pumps by PEO-PPO amphiphiles: Branched versus linear derivatives
    • Alvarez-Lorenzo C, Rey-Rico A, Brea J, et al. Inhibition of P-glycoprotein pumps by PEO-PPO amphiphiles: branched versus linear derivatives. Nanomedicine 2010;5:1371-83
    • (2010) Nanomedicine , vol.5 , pp. 1371-1383
    • Alvarez-Lorenzo, C.1    Rey-Rico, A.2    Brea, J.3
  • 41
    • 34249023676 scopus 로고    scopus 로고
    • Functionalized micellar systems for cancer targeted drug delivery
    • Sutton D, Nasongkla N, Blanco E, Gao J. Functionalized micellar systems for cancer targeted drug delivery. Pharm Res 2007;24:1029-46
    • (2007) Pharm Res , vol.24 , pp. 1029-1046
    • Sutton, D.1    Nasongkla, N.2    Blanco, E.3    Gao, J.4
  • 42
    • 71249135374 scopus 로고    scopus 로고
    • Nano-sized advanced delivery systems as parenteral formulation strategies for hydrophobic anti-cancer drugs
    • Villiers MM, de Aramwit P, Kwon GS, editors. Springer, AAPS Press; New York
    • Soo PL, Dunne M, Liu J, Allen C. Nano-sized advanced delivery systems as parenteral formulation strategies for hydrophobic anti-cancer drugs. In: Villiers MM, de Aramwit P, Kwon GS, editors. Nanotechnology in drug delivery. Springer, AAPS Press; New York: 2009. p. 349-83
    • (2009) Nanotechnology in Drug Delivery , pp. 349-383
    • Soo, P.L.1    Dunne, M.2    Liu, J.3    Allen, C.4
  • 43
    • 0028897485 scopus 로고
    • Physical entrapment of adriamycin in AB block copolymer micelles
    • Kwon G, Naito M, Yokoyama M, et al. Physical entrapment of adriamycin in AB block copolymer micelles. Pharm Res 1995;12:192-5
    • (1995) Pharm Res , vol.12 , pp. 192-195
    • Kwon, G.1    Naito, M.2    Yokoyama, M.3
  • 44
    • 0032671820 scopus 로고    scopus 로고
    • Investigations of naphthalene solubilization in aqueous solutions of ethylene oxide-b-propylene oxide-bethylene oxide copolymers
    • Paterson IF, Chowdhry BZ, Leharne SA. Investigations of naphthalene solubilization in aqueous solutions of ethylene oxide-b-propylene oxide-bethylene oxide copolymers. Langmuir 1999;15:6187-94
    • (1999) Langmuir , vol.15 , pp. 6187-6194
    • Paterson, I.F.1    Chowdhry, B.Z.2    Leharne, S.A.3
  • 45
    • 1242271298 scopus 로고    scopus 로고
    • The effects of Pluronic block copolymers on the aggregation state of nystatin
    • Croy SR, Kwon GS. The effects of Pluronic block copolymers on the aggregation state of nystatin. J Control Release 2004;95:161-71
    • (2004) J Control Release , vol.95 , pp. 161-171
    • Croy, S.R.1    Kwon, G.S.2
  • 46
    • 0035834246 scopus 로고    scopus 로고
    • Micelles self-assembled from poly (ethylene oxide)-block-poly(N-hexyl stearate L-aspartamide) by a solvent evaporation method: Effect on the solubilization and haemolytic activity of amphotericin B
    • Lavasanifar A, Samuel J, Kwon GS. Micelles self-assembled from poly (ethylene oxide)-block-poly(N-hexyl stearate L-aspartamide) by a solvent evaporation method: effect on the solubilization and haemolytic activity of amphotericin B. J Control Release 2001;77:155-60
    • (2001) J Control Release , vol.77 , pp. 155-160
    • Lavasanifar, A.1    Samuel, J.2    Kwon, G.S.3
  • 47
    • 84873424418 scopus 로고    scopus 로고
    • Drug loading of polymeric micelles
    • Miller T, Colen G, Sander B, et al. Drug loading of polymeric micelles. Pharm Res 2013;30:584-95
    • (2013) Pharm Res , vol.30 , pp. 584-595
    • Miller, T.1    Colen, G.2    Sander, B.3
  • 48
    • 33644839318 scopus 로고    scopus 로고
    • Poly(lactide)- poly(ethylene glycol) micelles as a carrier for griseofulvin
    • Pierri E, Avgoustakis K. Poly(lactide)- poly(ethylene glycol) micelles as a carrier for griseofulvin. J Biomed Mater Res A 2005;75A:639-47
    • (2005) J Biomed Mater Res A , vol.75 A , pp. 639-647
    • Pierri, E.1    Avgoustakis, K.2
  • 49
    • 33846443159 scopus 로고    scopus 로고
    • Hydrotropic polymeric micelles for enhanced paclitaxel solubility: In vitro and in vivo characterization
    • Lee SC, Huh KM, Lee J, et al. Hydrotropic polymeric micelles for enhanced paclitaxel solubility: in vitro and in vivo characterization. Biomacromolecules 2006;8:202-8
    • (2006) Biomacromolecules , vol.8 , pp. 202-208
    • Lee, S.C.1    Huh, K.M.2    Lee, J.3
  • 50
    • 4844222526 scopus 로고    scopus 로고
    • In vitro characterization of PEGylated phospholipid micelles for improved drug solubilization: Effects of PEG chain length and PC incorporation
    • Ashok B, Arleth L, Hjelm RP, et al. In vitro characterization of PEGylated phospholipid micelles for improved drug solubilization: effects of PEG chain length and PC incorporation. J Pharm Sci 2004;93:2476-87
    • (2004) J Pharm Sci , vol.93 , pp. 2476-2487
    • Ashok, B.1    Arleth, L.2    Hjelm, R.P.3
  • 51
    • 84886243687 scopus 로고    scopus 로고
    • Preparation and evaluation in vitro and in vivo of docetaxel loaded mixed micelles for oral administration
    • Dou J, Zhang H, Liu X, et al. Preparation and evaluation in vitro and in vivo of docetaxel loaded mixed micelles for oral administration. Colloids Surf B Biointerfaces 2014;114:20-7
    • (2014) Colloids Surf B Biointerfaces , vol.114 , pp. 20-27
    • Dou, J.1    Zhang, H.2    Liu, X.3
  • 52
    • 34848855357 scopus 로고    scopus 로고
    • Pharmaceutical evaluation of genisteinloaded pluronic micelles for oral delivery
    • Kwon S, Kim S, Ha K, et al. Pharmaceutical evaluation of genisteinloaded pluronic micelles for oral delivery. Arch Pharm Res 2007;30:1138-43
    • (2007) Arch Pharm Res , vol.30 , pp. 1138-1143
    • Kwon, S.1    Kim, S.2    Ha, K.3
  • 53
    • 0037394663 scopus 로고    scopus 로고
    • Stability and release performance of a series of pegylated copolymeric micelles
    • Lin WJ, Juang LW, Lin CC. Stability and release performance of a series of pegylated copolymeric micelles. Pharm Res 2003;20:668-73
    • (2003) Pharm Res , vol.20 , pp. 668-673
    • Lin, W.J.1    Juang, L.W.2    Lin, C.C.3
  • 54
    • 3042761142 scopus 로고    scopus 로고
    • A novel one-step drug-loading procedure for water-soluble amphiphilic nanocarriers
    • Fournier E, Dufresne MH, Smith D, et al. A novel one-step drug-loading procedure for water-soluble amphiphilic nanocarriers. Pharm Res 2004;21:962-8
    • (2004) Pharm Res , vol.21 , pp. 962-968
    • Fournier, E.1    Dufresne, M.H.2    Smith, D.3
  • 55
    • 59349103586 scopus 로고    scopus 로고
    • Anionic poly(lactic acid)-polyurethane micelles as potential biodegradable drug delivery carriers
    • Zhang J, Wu M, Yang J, et al. Anionic poly(lactic acid)-polyurethane micelles as potential biodegradable drug delivery carriers. Colloids Surf A Physicochem Eng Asp 2009;337:200-4
    • (2009) Colloids Surf a Physicochem Eng Asp , vol.337 , pp. 200-204
    • Zhang, J.1    Wu, M.2    Yang, J.3
  • 56
    • 77955980572 scopus 로고    scopus 로고
    • Effective polymeric dispersants for vacuum, convection and freeze drying of drug nanosuspensions
    • Kim S, Lee J. Effective polymeric dispersants for vacuum, convection and freeze drying of drug nanosuspensions. Int J Pharm 2010;397:218-24
    • (2010) Int J Pharm , vol.397 , pp. 218-224
    • Kim, S.1    Lee, J.2
  • 57
    • 84887772602 scopus 로고    scopus 로고
    • pH-responsive release of proteins from biocompatible and biodegradable reverse polymer micelles
    • Koyamatsu Y, Hirano T, Kakizawa Y, et al. pH-responsive release of proteins from biocompatible and biodegradable reverse polymer micelles. J Control Release 2014;173:89-95
    • (2014) J Control Release , vol.173 , pp. 89-95
    • Koyamatsu, Y.1    Hirano, T.2    Kakizawa, Y.3
  • 58
    • 82255163504 scopus 로고    scopus 로고
    • Sustained release of low molecular weight heparin from PLGA microspheres prepared by a solid-in-oil-in-water emulsion method
    • He J, Zhou Z, Fan Y, et al. Sustained release of low molecular weight heparin from PLGA microspheres prepared by a solid-in-oil-in-water emulsion method. J Microencapsul 2011;28:763-70
    • (2011) J Microencapsul , vol.28 , pp. 763-770
    • He, J.1    Zhou, Z.2    Fan, Y.3
  • 59
    • 19444375996 scopus 로고    scopus 로고
    • Enhancement of oral bioavailability of poorly water-soluble drugs by poly (ethylene glycol)-block-poly(alkyl acrylate-co-methacrylic acid) self-assemblies
    • Sant VP, Smith D, Leroux JC. Enhancement of oral bioavailability of poorly water-soluble drugs by poly (ethylene glycol)-block-poly(alkyl acrylate-co-methacrylic acid) self-assemblies. J Control Release 2005;104:289-300
    • (2005) J Control Release , vol.104 , pp. 289-300
    • Sant, V.P.1    Smith, D.2    Leroux, J.C.3
  • 60
    • 1642564456 scopus 로고    scopus 로고
    • Micellar formulations for drug delivery based on mixtures of hydrophobic and hydrophilic Pluronic® block copolymers
    • Oh KT, Bronich TK, Kabanov AV. Micellar formulations for drug delivery based on mixtures of hydrophobic and hydrophilic Pluronic® block copolymers. J Control Release 2004;94:411-22
    • (2004) J Control Release , vol.94 , pp. 411-422
    • Oh, K.T.1    Bronich, T.K.2    Kabanov, A.V.3
  • 61
    • 75149175575 scopus 로고    scopus 로고
    • Colloidal nanocarriers: A review on formulation technology, types and applications toward targeted drug delivery
    • Mishra B, Patel BB, Tiwari S. Colloidal nanocarriers: a review on formulation technology, types and applications toward targeted drug delivery. Nanomedicine 2010;6:9-24
    • (2010) Nanomedicine , vol.6 , pp. 9-24
    • Mishra, B.1    Patel, B.B.2    Tiwari, S.3
  • 62
    • 0035118380 scopus 로고    scopus 로고
    • Solubilization of "guest" molecules into polymeric aggregates
    • Nagarajan R. Solubilization of "guest" molecules into polymeric aggregates. Polym Adv Technol 2001;12:23-43
    • (2001) Polym Adv Technol , vol.12 , pp. 23-43
    • Nagarajan, R.1
  • 64
    • 20744449647 scopus 로고    scopus 로고
    • Block copolymers of ethylene oxide and phenyl glycidyl ether: Micellization, gelation, and drug solubilization
    • Taboada P, Velasquez G, Barbosa S, et al. Block copolymers of ethylene oxide and phenyl glycidyl ether: micellization, gelation, and drug solubilization. Langmuir 2005;21:5263-71
    • (2005) Langmuir , vol.21 , pp. 5263-5271
    • Taboada, P.1    Velasquez, G.2    Barbosa, S.3
  • 65
    • 36148960487 scopus 로고    scopus 로고
    • Block copolymers for drug solubilisation: Relative hydrophobicities of polyether and polyester micelle-core-forming blocks
    • Attwood D, Booth C, Yeates SG, et al. Block copolymers for drug solubilisation: relative hydrophobicities of polyether and polyester micelle-core-forming blocks. Int J Pharm 2007;345:35-41
    • (2007) Int J Pharm , vol.345 , pp. 35-41
    • Attwood, D.1    Booth, C.2    Yeates, S.G.3
  • 66
    • 58149108875 scopus 로고    scopus 로고
    • Preparation and drug controlled-release of polyion complex micelles as drug delivery systems
    • Luo Y, Yao X, Yuan J, et al. Preparation and drug controlled-release of polyion complex micelles as drug delivery systems. Colloids Surf B Biointerfaces 2009;68:218-24
    • (2009) Colloids Surf B Biointerfaces , vol.68 , pp. 218-224
    • Luo, Y.1    Yao, X.2    Yuan, J.3
  • 67
    • 44449158256 scopus 로고    scopus 로고
    • Supramolecular micellization of diblock copolymer mixtures mediated by hydrogen bonding for the observation of separated coil and chain aggregation in common solvents
    • Kuo SW, Tung PH, Lai CL, et al. Supramolecular micellization of diblock copolymer mixtures mediated by hydrogen bonding for the observation of separated coil and chain aggregation in common solvents. Macromol Rapid Commun 2008;29:229-33
    • (2008) Macromol Rapid Commun , vol.29 , pp. 229-233
    • Kuo, S.W.1    Tung, P.H.2    Lai, C.L.3
  • 68
    • 84875281946 scopus 로고    scopus 로고
    • Balance of coordination and hydrophobic interaction in the formation of bilayers in metal-coordinated surfactant mixtures
    • Tian H, Wang D, Xu W, et al. Balance of coordination and hydrophobic interaction in the formation of bilayers in metal-coordinated surfactant mixtures. Langmuir 2013;29:3538-45
    • (2013) Langmuir , vol.29 , pp. 3538-3545
    • Tian, H.1    Wang, D.2    Xu, W.3
  • 69
    • 78349299793 scopus 로고    scopus 로고
    • Reverse micelles from amphiphilic branched polymers
    • Jones MC, Leroux JC. Reverse micelles from amphiphilic branched polymers. Soft Matter 2010;6:5850-9
    • (2010) Soft Matter , vol.6 , pp. 5850-5859
    • Jones, M.C.1    Leroux, J.C.2
  • 71
    • 79955828496 scopus 로고    scopus 로고
    • Discovering multicore micelles: Insights into the self-assembly of linear ABC terpolymers in midblockselective solvents
    • Wang L, Lin J. Discovering multicore micelles: insights into the self-assembly of linear ABC terpolymers in midblockselective solvents. Soft Matter 2011;7:3383-91
    • (2011) Soft Matter , vol.7 , pp. 3383-3391
    • Wang, L.1    Lin, J.2
  • 72
    • 33645524712 scopus 로고    scopus 로고
    • Two-compartment micellar assemblies obtained via aqueous self-organization of synthetic polymer building blocks
    • Thünemann AF, Kubowicz S, von Berlepsch H, Möhwald H. Two-compartment micellar assemblies obtained via aqueous self-organization of synthetic polymer building blocks. Langmuir 2006;22:2506-10
    • (2006) Langmuir , vol.22 , pp. 2506-2510
    • Thünemann, A.F.1    Kubowicz, S.2    Von Berlepsch, H.3    Möhwald, H.4
  • 73
    • 33646370738 scopus 로고    scopus 로고
    • Assessment of the integrity of poly(caprolactone)-b-poly(ethylene oxide) micelles under biological conditions: A fluorogenic-based approach
    • Savić R, Azzam T, Eisenberg A, Maysinger D. Assessment of the integrity of poly(caprolactone)-b-poly(ethylene oxide) micelles under biological conditions: a fluorogenic-based approach. Langmuir 2006;22:3570-8
    • (2006) Langmuir , vol.22 , pp. 3570-3578
    • Savić, R.1    Azzam, T.2    Eisenberg, A.3    Maysinger, D.4
  • 75
    • 77952491719 scopus 로고    scopus 로고
    • Biopharmaceutical parameters to consider in order to alter the fate of nanocarriers after oral delivery
    • Roger E, Lagarce F, Garcion E, Benoit JP. Biopharmaceutical parameters to consider in order to alter the fate of nanocarriers after oral delivery. Nanomedicine 2010;5:287-306
    • (2010) Nanomedicine , vol.5 , pp. 287-306
    • Roger, E.1    Lagarce, F.2    Garcion, E.3    Benoit, J.P.4
  • 76
    • 0038184026 scopus 로고    scopus 로고
    • Micellization of block copolymers
    • Riess G. Micellization of block copolymers. Prog Polym Sci 2003;28:1107-70
    • (2003) Prog Polym Sci , vol.28 , pp. 1107-1170
    • Riess, G.1
  • 77
    • 33746836593 scopus 로고    scopus 로고
    • Self-association of block copoly (oxyalkylene)s in aqueous solution. Effects of composition, block length and block architecture
    • Booth C, Attwood D, Price C. Self-association of block copoly (oxyalkylene)s in aqueous solution. Effects of composition, block length and block architecture. Phys Chem Chem Phys 2006;8:3612-22
    • (2006) Phys Chem Chem Phys , vol.8 , pp. 3612-3622
    • Booth, C.1    Attwood, D.2    Price, C.3
  • 78
    • 16844369855 scopus 로고    scopus 로고
    • Engineering polysaccharidebased polymeric micelles to enhance permeability of cyclosporin A across caco-2 cells
    • Francis MF, Cristea M, Yang Y, Winnik FM. Engineering polysaccharidebased polymeric micelles to enhance permeability of cyclosporin A across caco-2 cells. Pharm Res 2005;22:209-19
    • (2005) Pharm Res , vol.22 , pp. 209-219
    • Francis, M.F.1    Cristea, M.2    Yang, Y.3    Winnik, F.M.4
  • 79
    • 79955034696 scopus 로고    scopus 로고
    • Enhancing effect of N-octyl-O-sulfate chitosan on etoposide absorption
    • Mo R, Xiao Y, Sun M, et al. Enhancing effect of N-octyl-O-sulfate chitosan on etoposide absorption. Int J Pharm 2011;409:38-45
    • (2011) Int J Pharm , vol.409 , pp. 38-45
    • Mo, R.1    Xiao, Y.2    Sun, M.3
  • 80
    • 84891777924 scopus 로고    scopus 로고
    • Inhibition mechanism of P-glycoprotein mediated efflux by mPEG-PLA and influence of PLA chain length on P-glycoprotein inhibition activity
    • Li W, Li X, Gao Y, et al. Inhibition mechanism of P-glycoprotein mediated efflux by mPEG-PLA and influence of PLA chain length on P-glycoprotein inhibition activity. Mol Pharm 2013;11:71-80
    • (2013) Mol Pharm , vol.11 , pp. 71-80
    • Li, W.1    Li, X.2    Gao, Y.3
  • 81
    • 51049097480 scopus 로고    scopus 로고
    • P-glycoprotein efflux inhibition by amphiphilic diblock copolymers: Relationship between copolymer concentration and substrate hydrophobicity
    • Zastre JA, Jackson JK, Wong W, Burt HM. P-glycoprotein efflux inhibition by amphiphilic diblock copolymers: relationship between copolymer concentration and substrate hydrophobicity. Mol Pharm 2008;5:643-53
    • (2008) Mol Pharm , vol.5 , pp. 643-653
    • Zastre, J.A.1    Jackson, J.K.2    Wong, W.3    Burt, H.M.4
  • 82
    • 33846861762 scopus 로고    scopus 로고
    • Investigation of pluronic and PEG-PE micelles as carriers of meso-tetraphenyl porphine for oral administration
    • Sezgin Z, Yuksel N, Baykara T. Investigation of pluronic and PEG-PE micelles as carriers of meso-tetraphenyl porphine for oral administration. Int J Pharm 2007;332:161-7
    • (2007) Int J Pharm , vol.332 , pp. 161-167
    • Sezgin, Z.1    Yuksel, N.2    Baykara, T.3
  • 83
    • 56949101192 scopus 로고    scopus 로고
    • Hydrotropic polymer micelles containing acrylic acid moieties for oral delivery of paclitaxel
    • Kim S, Kim JY, Huh KM, et al. Hydrotropic polymer micelles containing acrylic acid moieties for oral delivery of paclitaxel. J Control Release 2008;132:222-9
    • (2008) J Control Release , vol.132 , pp. 222-229
    • Kim, S.1    Kim, J.Y.2    Huh, K.M.3
  • 84
    • 22644435970 scopus 로고    scopus 로고
    • Thiol-functionalized polymeric micelles: From molecular recognition to improved mucoadhesion
    • Dufresne MH, Gauthier MA, Leroux JC. Thiol-functionalized polymeric micelles: from molecular recognition to improved mucoadhesion. Bioconjugate Chem 2005;16:1027-33
    • (2005) Bioconjugate Chem , vol.16 , pp. 1027-1033
    • Dufresne, M.H.1    Gauthier, M.A.2    Leroux, J.C.3
  • 85
    • 77955239415 scopus 로고    scopus 로고
    • Cyclosporin A-loaded poly(ethylene glycol)-b-poly(d,l-lactic acid) micelles: Preparation, in vitro and in vivo characterization and transport mechanism across the intestinal barrier
    • Zhang Y, Li X, Zhou Y, et al. Cyclosporin A-loaded poly(ethylene glycol)-b-poly(d,l-lactic acid) micelles: Preparation, in vitro and in vivo characterization and transport mechanism across the intestinal barrier. Mol Pharm 2010;7:1169-82
    • (2010) Mol Pharm , vol.7 , pp. 1169-1182
    • Zhang, Y.1    Li, X.2    Zhou, Y.3
  • 86
    • 0242352524 scopus 로고    scopus 로고
    • Solubilization of poorly water soluble drugs in micelles of hydrophobically modified hydroxypropylcellulose copolymers
    • Francis MF, Piredda M, Winnik FM. Solubilization of poorly water soluble drugs in micelles of hydrophobically modified hydroxypropylcellulose copolymers. J Control Release 2003;93:59-68
    • (2003) J Control Release , vol.93 , pp. 59-68
    • Francis, M.F.1    Piredda, M.2    Winnik, F.M.3
  • 87
    • 0242383500 scopus 로고    scopus 로고
    • Solubilization of cyclosporin A in dextran-g-polyethyleneglycolalkyl ether polymeric micelles
    • Francis MF, Lavoie L, Winnik FM, Leroux JC. Solubilization of cyclosporin A in dextran-g-polyethyleneglycolalkyl ether polymeric micelles. Eur J Pharm Biopharm 2003;56:337-46
    • (2003) Eur J Pharm Biopharm , vol.56 , pp. 337-346
    • Francis, M.F.1    Lavoie, L.2    Winnik, F.M.3    Leroux, J.C.4
  • 88
    • 3042555861 scopus 로고    scopus 로고
    • Solubilization and stabilization of camptothecin in micellar solutions of pluronic-g-poly(acrylic acid) copolymers
    • Barreiro-Iglesias R, Bromberg L, Temchenko M, et al. Solubilization and stabilization of camptothecin in micellar solutions of pluronic-g-poly(acrylic acid) copolymers. J Control Release 2004;97:537-49
    • (2004) J Control Release , vol.97 , pp. 537-549
    • Barreiro-Iglesias, R.1    Bromberg, L.2    Temchenko, M.3
  • 89
    • 78149388460 scopus 로고    scopus 로고
    • Polymeric micelles as drug stabilizers: The camptothecin and simvastatin cases
    • Alvarez-Lorenzo C, Concheiro A. Polymeric micelles as drug stabilizers: the camptothecin and simvastatin cases. J Drug Deliv Sci Technol 2010;20:249-57
    • (2010) J Drug Deliv Sci Technol , vol.20 , pp. 249-257
    • Alvarez-Lorenzo, C.1    Concheiro, A.2
  • 90
    • 5644247597 scopus 로고    scopus 로고
    • Pluronic block copolymers and Pluronic poly(acrylic acid) microgels in oral delivery of megestrol acetate
    • Alakhov V, Pietrzynski G, Patel K, et al. Pluronic block copolymers and Pluronic poly(acrylic acid) microgels in oral delivery of megestrol acetate. J Pharm Pharmacol 2004;56:1233-41
    • (2004) J Pharm Pharmacol , vol.56 , pp. 1233-1241
    • Alakhov, V.1    Pietrzynski, G.2    Patel, K.3
  • 91
    • 84879462668 scopus 로고    scopus 로고
    • Drug delivery by polymeric micelles: An in vitro and in vivo study to deliver lipophilic substances to colonocytes and selectively target inflamed colon
    • Valerii MC, Benaglia M, Caggiano C, et al. Drug delivery by polymeric micelles: an in vitro and in vivo study to deliver lipophilic substances to colonocytes and selectively target inflamed colon. Nanomedicine 2013;9:675-85
    • (2013) Nanomedicine , vol.9 , pp. 675-685
    • Valerii, M.C.1    Benaglia, M.2    Caggiano, C.3
  • 92
    • 84881667422 scopus 로고    scopus 로고
    • Suppression of NSAID-induced small intestinal inflammation by orally administered redox nanoparticles
    • Sha S, Vong LB, Chonpathompikunlert P, et al. Suppression of NSAID-induced small intestinal inflammation by orally administered redox nanoparticles. Biomaterials 2013;34:8393-400
    • (2013) Biomaterials , vol.34 , pp. 8393-8400
    • Sha, S.1    Vong, L.B.2    Chonpathompikunlert, P.3
  • 93
    • 84901408959 scopus 로고    scopus 로고
    • Oral nanotherapeutics: Effect of redox nanoparticle on microflora in mice with dextran sodium sulfate-induced colitis
    • Vong L, Yoshitomi T, Morikawa K, et al. Oral nanotherapeutics: effect of redox nanoparticle on microflora in mice with dextran sodium sulfate-induced colitis. J Gastroenterol 2014;49:806-13
    • (2014) J Gastroenterol , vol.49 , pp. 806-813
    • Vong, L.1    Yoshitomi, T.2    Morikawa, K.3
  • 94
    • 84890942840 scopus 로고    scopus 로고
    • Indomethacin-loaded redox nanoparticles improve oral bioavailability of indomethacin and suppress its small intestinal inflammation
    • Yoshitomi T, Sha S, Vong LB, et al. Indomethacin-loaded redox nanoparticles improve oral bioavailability of indomethacin and suppress its small intestinal inflammation. Ther Deliv 2013;5:29-38
    • (2013) Ther Deliv , vol.5 , pp. 29-38
    • Yoshitomi, T.1    Sha, S.2    Vong, L.B.3
  • 95
    • 84921511636 scopus 로고    scopus 로고
    • Design of complex micelles for drug delivery
    • Shen Y, editor. The Royal Society of Chemistry; London
    • Ma R, Shi L. Design of complex micelles for drug delivery. In: Shen Y, editor. Functional polymers for nanomedicine. The Royal Society of Chemistry; London: 2013. pp 207-26
    • (2013) Functional Polymers for Nanomedicine , pp. 207-226
    • Ma, R.1    Shi, L.2
  • 96
    • 23944513297 scopus 로고    scopus 로고
    • Dendrimeric micelles for controlled drug release and targeted delivery
    • Ambade AV, Savariar EN, Thayumanavan S. Dendrimeric micelles for controlled drug release and targeted delivery. Mol Pharm 2005;2:264-72
    • (2005) Mol Pharm , vol.2 , pp. 264-272
    • Ambade, A.V.1    Savariar, E.N.2    Thayumanavan, S.3
  • 97
    • 57049179546 scopus 로고    scopus 로고
    • Reverse polymeric micelles for pharmaceutical applications
    • Jones MC, Gao H, Leroux JC. Reverse polymeric micelles for pharmaceutical applications. J Control Release 2008;123:208-15
    • (2008) J Control Release , vol.123 , pp. 208-215
    • Jones, M.C.1    Gao, H.2    Leroux, J.C.3
  • 98
    • 65249127996 scopus 로고    scopus 로고
    • Block copolymer micelles as nanocontainers for controlled release of proteins from biocompatible oil phases
    • Miller AC, Bershteyn A, Tan W, et al. Block copolymer micelles as nanocontainers for controlled release of proteins from biocompatible oil phases. Biomacromolecules 2009;10:732-41
    • (2009) Biomacromolecules , vol.10 , pp. 732-741
    • Miller, A.C.1    Bershteyn, A.2    Tan, W.3
  • 99
    • 67349199522 scopus 로고    scopus 로고
    • Mixed micelle systems formed from critical micelle concentration and temperaturesensitive diblock copolymers for doxorubicin delivery
    • Lo CL, Lin SJ, Tsai HC, et al. Mixed micelle systems formed from critical micelle concentration and temperaturesensitive diblock copolymers for doxorubicin delivery. Biomaterials 2009;30:3961-70
    • (2009) Biomaterials , vol.30 , pp. 3961-3970
    • Lo, C.L.1    Lin, S.J.2    Tsai, H.C.3
  • 100
    • 67349137876 scopus 로고    scopus 로고
    • Paclitaxel-loaded Pluronic P123/ F127 mixed polymeric micelles: Formulation, optimization and in vitro characterization
    • Wei Z, Hao J, Yuan S, et al. Paclitaxel-loaded Pluronic P123/ F127 mixed polymeric micelles: formulation, optimization and in vitro characterization. Int J Pharm 2009;376:176-85
    • (2009) Int J Pharm , vol.376 , pp. 176-185
    • Wei, Z.1    Hao, J.2    Yuan, S.3
  • 101
    • 84866179290 scopus 로고    scopus 로고
    • Single and mixed poloxamine micelles as nanocarriers for solubilization and sustained release of ethoxzolamide for topical glaucoma therapy
    • Ribeiro A, Sosnik A, Chiappetta DA, et al. Single and mixed poloxamine micelles as nanocarriers for solubilization and sustained release of ethoxzolamide for topical glaucoma therapy. J R Soc Interface 2012;9:2059-69
    • (2012) J R Soc Interface , vol.9 , pp. 2059-2069
    • Ribeiro, A.1    Sosnik, A.2    Chiappetta, D.A.3
  • 102
    • 0035850224 scopus 로고    scopus 로고
    • Structure and design of polymeric surfactant-based drug delivery systems
    • Torchilin VP. Structure and design of polymeric surfactant-based drug delivery systems. J Control Release 2001;73:137-72
    • (2001) J Control Release , vol.73 , pp. 137-172
    • Torchilin, V.P.1
  • 103
    • 79955976339 scopus 로고    scopus 로고
    • Mixed micelles self-assembled from block copolymers for drug delivery
    • Attia ABE, Ong ZY, Hedrick JL, et al. Mixed micelles self-assembled from block copolymers for drug delivery. Curr Opin Colloid Interface Sci 2011;16:182-94
    • (2011) Curr Opin Colloid Interface Sci , vol.16 , pp. 182-194
    • Attia, A.B.E.1    Ong, Z.Y.2    Hedrick, J.L.3
  • 104
    • 61649094555 scopus 로고    scopus 로고
    • Mixed micelle formation through stereocomplexation between enantiomeric poly(lactide) block copolymers
    • Kim SH, Tan JPK, Nederberg F, et al. Mixed micelle formation through stereocomplexation between enantiomeric poly(lactide) block copolymers. Macromolecules 2008;42:25-9
    • (2008) Macromolecules , vol.42 , pp. 25-29
    • Kim, S.H.1    Tan, J.P.K.2    Nederberg, F.3
  • 105
    • 84872099658 scopus 로고    scopus 로고
    • A selfassembled nanocarrier loading teniposide improves the oral delivery and drug concentration in tumor
    • Zhang Z, Ma L, Jiang S, et al. A selfassembled nanocarrier loading teniposide improves the oral delivery and drug concentration in tumor. J Control Release 2013;166:30-7
    • (2013) J Control Release , vol.166 , pp. 30-37
    • Zhang, Z.1    Ma, L.2    Jiang, S.3
  • 106
    • 0032867434 scopus 로고    scopus 로고
    • Block copolymer-based formulation of doxorubicin. From cell screen to clinical trials
    • Alakhov V, Klinski E, Li S, et al. Block copolymer-based formulation of doxorubicin. From cell screen to clinical trials. Colloids Surf B Biointerfaces 1999;16:113-34
    • (1999) Colloids Surf B Biointerfaces , vol.16 , pp. 113-134
    • Alakhov, V.1    Klinski, E.2    Li, S.3
  • 107
    • 74449089561 scopus 로고    scopus 로고
    • The effects of mixed MPEG-PLA/ Pluronic® copolymer micelles on the bioavailability and multidrug resistance of docetaxel
    • Mu CF, Balakrishnan P, Cui FD, et al. The effects of mixed MPEG-PLA/ Pluronic® copolymer micelles on the bioavailability and multidrug resistance of docetaxel. Biomaterials 2010;31:2371-9
    • (2010) Biomaterials , vol.31 , pp. 2371-2379
    • Mu, C.F.1    Balakrishnan, P.2    Cui, F.D.3
  • 108
    • 67349175012 scopus 로고    scopus 로고
    • Extracellular matrix binding mixed micelles for drug delivery applications
    • O'Neil CP, van der Vlies AJ, Velluto D, et al. Extracellular matrix binding mixed micelles for drug delivery applications. J Control Release 2009;137:146-51
    • (2009) J Control Release , vol.137 , pp. 146-151
    • O'Neil, C.P.1    Van Der Vlies, A.J.2    Velluto, D.3
  • 109
    • 80053203747 scopus 로고    scopus 로고
    • Synergistic encapsulation of the anti-HIV agent efavirenz within mixed poloxamine/poloxamer polymeric micelles
    • Chiappetta DA, Facorro G, Celis ER, Sosnik A. Synergistic encapsulation of the anti-HIV agent efavirenz within mixed poloxamine/poloxamer polymeric micelles. Nanomedicine 2011;7:624-37
    • (2011) Nanomedicine , vol.7 , pp. 624-637
    • Chiappetta, D.A.1    Facorro, G.2    Celis, E.R.3    Sosnik, A.4
  • 110
    • 75949086100 scopus 로고    scopus 로고
    • Efavirenz-loaded polymeric micelles for pediatric anti-HIV pharmacotherapy with significantly higher oral bioavailability
    • Chiappetta DA, Hocht C, Taira C, Sosnik A. Efavirenz-loaded polymeric micelles for pediatric anti-HIV pharmacotherapy with significantly higher oral bioavailability. Nanomedicine 2010;5:11-23
    • (2010) Nanomedicine , vol.5 , pp. 11-23
    • Chiappetta, D.A.1    Hocht, C.2    Taira, C.3    Sosnik, A.4
  • 111
    • 78751705732 scopus 로고    scopus 로고
    • Oral pharmacokinetics of the anti-HIV efavirenz encapsulated within polymeric micelles
    • Chiappetta DA, Hocht C, Taira C, Sosnik A. Oral pharmacokinetics of the anti-HIV efavirenz encapsulated within polymeric micelles. Biomaterials 2011;32:2379-87
    • (2011) Biomaterials , vol.32 , pp. 2379-2387
    • Chiappetta, D.A.1    Hocht, C.2    Taira, C.3    Sosnik, A.4
  • 112
    • 84861126620 scopus 로고    scopus 로고
    • Controlled release of ionic drugs from complex micelles with charged channels
    • Liu X, Ma R, Shen J, et al. Controlled release of ionic drugs from complex micelles with charged channels. Biomacromolecules 2012;13:1307-14
    • (2012) Biomacromolecules , vol.13 , pp. 1307-1314
    • Liu, X.1    Ma, R.2    Shen, J.3
  • 113
    • 73649084082 scopus 로고    scopus 로고
    • Self-assembled micelles based on PEGpolypeptide hybrid copolymers for drug delivery
    • Hua SH, Li YY, Liu Y, et al. Self-assembled micelles based on PEGpolypeptide hybrid copolymers for drug delivery. Macromol Rapid Commun 2010;31:81-6
    • (2010) Macromol Rapid Commun , vol.31 , pp. 81-86
    • Hua, S.H.1    Li, Y.Y.2    Liu, Y.3
  • 114
    • 33645783017 scopus 로고    scopus 로고
    • Novel drug release profiles from micellar solutions of PLA-PEO-PLA triblock copolymers
    • Agrawal SK, Sanabria-DeLong N, Coburn JM, et al. Novel drug release profiles from micellar solutions of PLA-PEO-PLA triblock copolymers. J Control Release 2006;112:64-71
    • (2006) J Control Release , vol.112 , pp. 64-71
    • Agrawal, S.K.1    Sanabria-DeLong, N.2    Coburn, J.M.3
  • 115
    • 84856835435 scopus 로고    scopus 로고
    • Cryoprotection-lyophilization and physical stabilization of rifampicinloaded flower-like polymeric micelles
    • Moretton MA, Chiappetta DA, Sosnik A. Cryoprotection-lyophilization and physical stabilization of rifampicinloaded flower-like polymeric micelles. J R Soc Interface 2012;9:487-502
    • (2012) J R Soc Interface , vol.9 , pp. 487-502
    • Moretton, M.A.1    Chiappetta, D.A.2    Sosnik, A.3
  • 116
    • 84902343814 scopus 로고    scopus 로고
    • 'Flower-like' polymeric micelles for enhanced oral bioavailability in an extemporaneous liquid fixed-dose combination with isoniazid
    • Epub ahead of print
    • Moretton MA, Hocht C, Taira C, Sosnik A. Rifampicin-loaded 'flower-like' polymeric micelles for enhanced oral bioavailability in an extemporaneous liquid fixed-dose combination with isoniazid. Nanomedicine 2014. [Epub ahead of print]
    • (2014) Nanomedicine
    • Moretton, M.A.1    Hocht, C.2    Taira, C.3    Rifampicin-loaded, S.A.4
  • 117
    • 84864511390 scopus 로고    scopus 로고
    • pH-sensitive vesicles, polymeric micelles, and nanospheres prepared with polycarboxylates
    • Felber AE, Dufresne MH, Leroux JC. pH-sensitive vesicles, polymeric micelles, and nanospheres prepared with polycarboxylates. Adv Drug Deliv Rev 2012;64:979-92
    • (2012) Adv Drug Deliv Rev , vol.64 , pp. 979-992
    • Felber, A.E.1    Dufresne, M.H.2    Leroux, J.C.3
  • 118
    • 84861632555 scopus 로고    scopus 로고
    • Synthesis and physicochemical characterization of amphiphilic triblock copolymer brush containing pH-sensitive linkage for oral drug delivery
    • Yang YQ, Lin WJ, Zhao B, et al. Synthesis and physicochemical characterization of amphiphilic triblock copolymer brush containing pH-sensitive linkage for oral drug delivery. Langmuir 2012;28:8251-9
    • (2012) Langmuir , vol.28 , pp. 8251-8259
    • Yang, Y.Q.1    Lin, W.J.2    Zhao, B.3
  • 119
    • 33847337418 scopus 로고    scopus 로고
    • pH-responsive polymeric micelles of poly(ethylene glycol)-b-poly (alkyl(meth)acrylate-co-methacrylic acid): Influence of the copolymer composition on self-assembling properties and release of candesartan cilexetil
    • Satturwar P, Eddine MN, Ravenelle F, Leroux JC. pH-responsive polymeric micelles of poly(ethylene glycol)-b-poly (alkyl(meth)acrylate-co-methacrylic acid): Influence of the copolymer composition on self-assembling properties and release of candesartan cilexetil. Eur J Pharm Biopharm 2007;65:379-87
    • (2007) Eur J Pharm Biopharm , vol.65 , pp. 379-387
    • Satturwar, P.1    Eddine, M.N.2    Ravenelle, F.3    Leroux, J.C.4
  • 120
    • 2942516895 scopus 로고    scopus 로고
    • Novel pH-sensitive supramolecular assemblies for oral delivery of poorly water soluble drugs: Preparation and characterization
    • Sant VP, Smith D, Leroux JC. Novel pH-sensitive supramolecular assemblies for oral delivery of poorly water soluble drugs: preparation and characterization. J Control Release 2004;97:301-12
    • (2004) J Control Release , vol.97 , pp. 301-312
    • Sant, V.P.1    Smith, D.2    Leroux, J.C.3
  • 121
    • 0038793493 scopus 로고    scopus 로고
    • pH-sensitive unimolecular polymeric micelles:Synthesis of a novel drug carrier
    • Jones MC, Ranger M, Leroux JC. pH-sensitive unimolecular polymeric micelles:synthesis of a novel drug carrier. Bioconjug Chem 2003;14:774-81
    • (2003) Bioconjug Chem , vol.14 , pp. 774-781
    • Jones, M.C.1    Ranger, M.2    Leroux, J.C.3
  • 122
    • 84894444652 scopus 로고    scopus 로고
    • pH-sensitive polymeric micelles triggered drug release for extracellular and intracellular drug targeting delivery
    • Liu Y, Wang W, Yang J, et al. pH-sensitive polymeric micelles triggered drug release for extracellular and intracellular drug targeting delivery. Asian J Pharm Sci 2013;8:159-67
    • (2013) Asian J Pharm Sci , vol.8 , pp. 159-167
    • Liu, Y.1    Wang, W.2    Yang, J.3
  • 123
    • 84899849685 scopus 로고    scopus 로고
    • Adoption of polymeric micelles to enhance the oral bioavailability of dexibuprofen: Formulation, in-vitro evaluation and invivo pharmacokinetic study in healthy human volunteers
    • Abdelbary G, Makhlouf A. Adoption of polymeric micelles to enhance the oral bioavailability of dexibuprofen: formulation, in-vitro evaluation and invivo pharmacokinetic study in healthy human volunteers. Pharm Dev Technol 2014;19:717-27
    • (2014) Pharm Dev Technol , vol.19 , pp. 717-727
    • Abdelbary, G.1    Makhlouf, A.2
  • 124
    • 84870323795 scopus 로고    scopus 로고
    • Treating acute cystitis with biodegradable micelle-encapsulated quercetin
    • Wang BL, Gao X, Men K, et al. Treating acute cystitis with biodegradable micelle-encapsulated quercetin. Int J Nanomedicine 2012;7:2239-47
    • (2012) Int J Nanomedicine , vol.7 , pp. 2239-2247
    • Wang, B.L.1    Gao, X.2    Men, K.3
  • 125
    • 33846498531 scopus 로고    scopus 로고
    • A mixed polymeric micellar formulation of itraconazole: Characteristics, toxicity and pharmacokinetics
    • Yi Y, Yoon HJ, Kim BO, et al. A mixed polymeric micellar formulation of itraconazole: characteristics, toxicity and pharmacokinetics. J Control Release 2007;117:59-67
    • (2007) J Control Release , vol.117 , pp. 59-67
    • Yi, Y.1    Yoon, H.J.2    Kim, B.O.3
  • 126
    • 84865294345 scopus 로고    scopus 로고
    • Stabilized micelles as delivery vehicles for paclitaxel
    • Yoncheva K, Calleja P, Agüeros M, et al. Stabilized micelles as delivery vehicles for paclitaxel. Int J Pharm 2012;436:258-64
    • (2012) Int J Pharm , vol.436 , pp. 258-264
    • Yoncheva, K.1    Calleja, P.2    Agüeros, M.3
  • 127
    • 12844273736 scopus 로고    scopus 로고
    • Self-assembling PEG-p(CL-co- TMC) copolymers for oral delivery of poorly water-soluble drugs: A case study with risperidone
    • Ould-Ouali L, Noppe M, Langlois X, et al. Self-assembling PEG-p(CL-co- TMC) copolymers for oral delivery of poorly water-soluble drugs: a case study with risperidone. J Control Release 2005;102:657-68
    • (2005) J Control Release , vol.102 , pp. 657-668
    • Ould-Ouali, L.1    Noppe, M.2    Langlois, X.3
  • 128
    • 36148935211 scopus 로고    scopus 로고
    • Transport mechanisms of mmePEG750P (CL-co-TMC) polymeric micelles across the intestinal barrier
    • Mathot F, Rieux A, Ariën A, et al. Transport mechanisms of mmePEG750P (CL-co-TMC) polymeric micelles across the intestinal barrier. J Control Release 2007;124:134-43
    • (2007) J Control Release , vol.124 , pp. 134-143
    • Mathot, F.1    Rieux, A.2    Ariën, A.3
  • 129
    • 84866854777 scopus 로고    scopus 로고
    • The use of polyion complex micelles to enhance the oral delivery of salmon calcitonin and transport mechanism across the intestinal epithelial barrier
    • Li N, Li XR, Zhou YX, et al. The use of polyion complex micelles to enhance the oral delivery of salmon calcitonin and transport mechanism across the intestinal epithelial barrier. Biomaterials 2012;33:8881-92
    • (2012) Biomaterials , vol.33 , pp. 8881-8892
    • Li, N.1    Li, X.R.2    Zhou, Y.X.3
  • 130
    • 84879581427 scopus 로고    scopus 로고
    • Enhanced solubility and oral absorption of sirolimus using D-alpha-tocopheryl polyethylene glycol succinate micelles
    • Kim MS, Kim JS, Cho WK, Hwang SJ. Enhanced solubility and oral absorption of sirolimus using D-alpha-tocopheryl polyethylene glycol succinate micelles. Artif Cells Nanomed Biotechnol 2013;41:85-91
    • (2013) Artif Cells Nanomed Biotechnol , vol.41 , pp. 85-91
    • Kim, M.S.1    Kim, J.S.2    Cho, W.K.3    Hwang, S.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.