Single and mixed poloxamine micelles as nanocarriers for solubilization and sustained release of ethoxzolamide for topical glaucoma therapy

Journal of the Royal Society Interface

Volumn 9, Issue 74, 2012, Pages 2059-2069

  Ribeiro, Andreza ^a,b   Sosnik, Alejandro ^c,d   Chiappetta, Diego A ^c,d   Veiga, Francisco ^a   Concheiro, Angel ^b   Alvarez Lorenzo, Carmen ^b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^d Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

Carbonic anhydrase inhibitor solubilization; Ethoxzolamide; Ocular delivery; Poloxamine; Poly(ethylene oxide) poly(propylene oxide) block copolymer; Polymeric micelles

Indexed keywords

BLOCK COPOLYMERS; CARBONIC ANHYDRASE; COAL TAR; DRUG PRODUCTS; HYDROPHILICITY; LOADING; OPHTHALMOLOGY; POLYETHYLENE OXIDES; POLYMERS; PROPYLENE; SODIUM CHLORIDE; SOLUBILITY;

ADDITIVE RULE; CLOUD POINTS; CRITICAL MICELLAR CONCENTRATIONS; DRUG RELEASE; DRUG SOLUBILIZATION; ETHOXZOLAMIDE; ETHYLENE OXIDES; GLAUCOMA THERAPY; MIXED MICELLES; NANOCARRIERS; OCULAR DELIVERY; PHYSICAL STABILITY; POLOXAMINES; POLYMERIC MICELLE; PROPYLENE OXIDE; SIMILAR NUMBERS; STRUCTURAL FEATURE; SUSTAINED RELEASE; TETRONIC;

MICELLES;

COPOLYMER; ETHOXZOLAMIDE; NANOCARRIER; POLOXAMINE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; GLAUCOMA; MICELLE; NONHUMAN;

EID: 84866179290     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2012.0102     Document Type: Article

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