P-glycoprotein efflux inhibition by amphiphilic diblock copolymers: Relationship between copolymer concentration and substrate hydrophobicity

Molecular Pharmaceutics

Volumn 5, Issue 4, 2008, Pages 643-653

  Zastre, Jason A ^a   Jackson, John K ^b   Wong, Wesley ^b   Burt, Helen M ^b  

^a UNIVERSITY OF GEORGIA   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Caco 2; Diblock copolymer; P glycoprotein; Surfactant

Indexed keywords

ALPHA TOCOPHEROL; COPOLYMER; DOXORUBICIN; GLYCOPROTEIN P; MACROGOL DERIVATIVE; PACLITAXEL; POLYCAPROLACTONE; RHODAMINE 123; RHODAMINE 6G; SURFACTANT; TOCOFERSOLAN;

CELL ADHESION; CELL STRAIN CACO 2; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; CONTROLLED STUDY; CORRELATIONAL STUDY; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; MICELLE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SEQUENCE HOMOLOGY;

CACO-2 CELLS; DOXORUBICIN; ETHYLENE OXIDE; HUMANS; HYDROPHOBICITY; LACTONES; MOLECULAR STRUCTURE; P-GLYCOPROTEIN; PACLITAXEL; POLYETHYLENE GLYCOLS; SURFACE-ACTIVE AGENTS;

EID: 51049097480     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp7001347     Document Type: Conference Paper

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