Novel pH-sensitive supramolecular assemblies for oral delivery of poorly water soluble drugs: Preparation and characterization

Journal of Controlled Release

Volumn 97, Issue 2, 2004, Pages 301-312

  Sant, Vinayak P ^a   Smith, Damon ^b   Leroux, Jean Christophe ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b Labopharm Inc   (Canada)

Author keywords

ATRP; Hydrophobic drugs; Micelles; Oral delivery; pH sensitive

Indexed keywords

COPOLYMERS; DIALYSIS; HORMONES; PH EFFECTS; SOLUBILITY; SUPRAMOLECULAR CHEMISTRY;

SUPRAMOLECULAR ASSEMBLIES; WATER-SOLUBLE DRUGS;

DRUG PRODUCTS;

ACRYLIC ACID BUTYL ESTER; ACRYLIC ACID ETHYL ESTER; COPOLYMER; DICHLOROMETHANE; FENOFIBRATE; INDOMETACIN; MACROGOL; METHACRYLIC ACID DERIVATIVE; PROGESTERONE; WATER;

ARTICLE; ATOM TRANSFER RADICAL POLYMERIZATION; CHEMICAL COMPOSITION; DIALYSIS; DISPERSION; DRUG DELIVERY SYSTEM; DRUG HYDROLYSIS; DRUG RELEASE; DRUG SOLUBILITY; DRUG SYNTHESIS; EMULSION; HYDROPHOBICITY; IN VITRO STUDY; MOLECULAR WEIGHT; PH MEASUREMENT; PRIORITY JOURNAL;

ACRYLIC RESINS; ADMINISTRATION, ORAL; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; DRUG COMPOUNDING; EMULSIONS; HYDROGEN-ION CONCENTRATION; INDOMETHACIN; MICELLES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYMETHACRYLIC ACIDS; PROCETOFEN; SOLUBILITY; TIME FACTORS; WATER;

EID: 2942516895     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2004.03.026     Document Type: Article

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