A self-assembled nanocarrier loading teniposide improves the oral delivery and drug concentration in tumor

Journal of Controlled Release

Volumn 166, Issue 1, 2013, Pages 30-37

  Zhang, Zhiwen ^a   Ma, Li ^b   Jiang, Shijun ^c   Liu, Zeying ^c   Huang, Jian ^a   Chen, Lingli ^a   Yu, Haijun ^a   Li, Yaping ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b HUBEI UNIVERSITY OF CHINESE MEDICINE   (China)

^c EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Nanocarrier; Nanoparticles; Oral delivery; Self assembly; Teniposide

Indexed keywords

CACO-2 CELLS; CELLULAR UPTAKE; DRUG CONCENTRATION; ENDOCYTOSIS PATHWAY; INCUBATION TIME; INTESTINAL ABSORPTION; NANOCARRIERS; NANOMETRIC PARTICLES; NARROW SIZE DISTRIBUTIONS; ORAL ADMINISTRATION; ORAL DELIVERY; PORTAL VEINS; SELF-ASSEMBLED; SYSTEMIC CIRCULATION; TENIPOSIDE;

CELLS; CHEMOTHERAPY; MOLECULAR BIOLOGY; MONOLAYERS; NANOPARTICLES; SELF ASSEMBLY; TUMORS;

ENZYME INHIBITION;

SELF ASSEMBLED MONOLAYER; TENIPOSIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG TRANSPORT; DRUG UPTAKE; DUODENUM; ENDOCYTOSIS; JEJUNUM; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; TUMOR XENOGRAFT;

ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS; CACO-2 CELLS; CELL PROLIFERATION; DRUG CARRIERS; DUODENUM; ENDOCYTOSIS; HUMANS; INTESTINAL ABSORPTION; JEJUNUM; MALE; MCF-7 CELLS; MICE; MICE, INBRED ICR; NANOPARTICLES; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY; TENIPOSIDE; TISSUE DISTRIBUTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84872099658     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.12.018     Document Type: Article

References (33)

1. L. Bromberg Polymeric micelles in oral chemotherapy J. Control. Release 128 2008 99 112
2. O. Benny, O. Fainaru, A. Adini, F. Cassiola, L. Bazinet, I. Adini, E. Pravda, Y. Nahmias, S. Koirala, G. Corfas, R.J. D'Amato, and J. Folkman An orally delivered small-molecule formulation with antiangiogenic and anticancer activity Nat. Biotechnol. 26 2008 799 807
3. A.K. Jain, N.K. Swarnakar, C. Godugu, R.P. Singh, and S. Jain The effect of the oral administration of polymeric nanoparticles on the efficacy and toxicity of tamoxifen Biomaterials 32 2011 503 515
4. D.D. Mosel, R.L. Bauer, D.P. Lynch, and S.T. Hwang Oral complications in the treatment of cancer patients Oral Dis. 17 2011 550 559
5. A. Bottomley The cancer patient and quality of life Oncologist 7 2002 120 125
6. G.L. Banna, E. Collovà, V. Gebbia, H. Lipari, P. Giuffrida, S. Cavallaro, R. Condorelli, C. Buscarino, P. Tralongo, and F. Ferraù Anticancer oral therapy: emerging related issues Cancer Treat. Rev. 36 2010 595 605
7. D.M.K. Keefe, and E.H. Bateman Tumor control versus adverse events with targeted anticancer therapies Nat. Rev. Clin. Oncol. 9 2012 98 109
8. M.E. Davis, Z.G. Chen, and D.M. Shin Nanoparticle therapeutics: an emerging treatment modality for cancer Nat. Rev. Drug Discov. 7 2008 771 782
9. P. Sonneveld Teniposide in lymphomas and leukemias Semin. Oncol. 19 1992 59 64
10. P.I. Clark, and M.L. Slevin The clinical pharmacology of etoposide and teniposide Clin. Pharmacokinet. 12 1987 223 252
11. Vumon(teniposide injection) http://www.accessdata.fda.gov/drugsatfdadocs/ label/2011/020119s010s011lbl.pdf
12. L.G. Sylvester, A. Marini, H. Landy, A. Markoe, D. Heros, C. Robles, C. Herrera, and N. Savaraj Clinical trial of CPT-11 and VM-26/VP-16 for patients with recurrent malignant brain tumors J. Neurooncol 82 2007 177 181
13. J.T. Hartmann, and H.P. Lipp Camptothecin and podophyllotoxin derivatives: inhibitors of topoisomerase I and II - mechanisms of action, pharmacokinetics and toxicity profile Drug Saf. 29 2006 209 230
14. Q. Chen, S.C. Bae, and S. Granick Directed self-assembly of nanoparticles ACS Nano 4 2010 3591 3602
15. S. Kim, J.Y. Kim, K.M. Huh, G. Acharya, and K. Park Hydrotropic polymer micelles containing acrylic acid moieties for oral delivery of paclitaxel J. Control. Release 131 2008 222 229
16. R. Mo, X. Jin, N. Li, C. Ju, M. Sun, C. Zhang, and Q. Ping The mechanism of enhancement on oral absorption of paclitaxel by N-octyl-O-sulfate chitosan micelles Biomaterials 32 2011 4609 4620
17. Z. Zhang, Y. Huang, F. Gao, Z. Gao, H. Bu, W. Gu, and Y. Li A self-assembled nanodelivery system enhances the oral bioavailability of daidzein: in vitro characteristics and in vivo performance Nanomedicine (London) 6 2011 1365 1379
18. M. Danquah, T. Fujiwara, and R.I. Mahato Self-assembling methoxypoly(ethylene glycol)-b-poly (carbonate-co-L-lactide) block copolymers for drug delivery Biomaterials 31 2010 2358 2370
19. X. Sha, G. Yan, Y. Wu, J. Li, and X. Fang Effect of self-microemulsifying drug delivery systems containing Labrasol on tight junctions in Caco-2 cells Eur. J. Pharm. Sci. 24 2005 477 486
20. F. Gao, Z. Zhang, H. Bu, Y. Huang, Z. Gao, J. Shen, C. Zhao, and Y. Li Nanoemulsion improves the oral absorption of candesartan cilexetil in rats: performance and mechanism J. Control. Release 149 2011 168 174
21. E. Roger, F. Lagarce, E. Garcion, and J.P. Benoit Lipid nanocarriers improve paclitaxel transport through human intestinal epithelial cells by using vesicle-mediated transcytosis J. Control. Release 140 2009 174 181
22. P. Ho, T. Yeh, H. Yao, H. Lin, H. Wu, Y. Lo, Y. Chang, T. Chiang, S.H.W. Wu, Y. Chao, and C. Chen Enhanced oral bioavailability of paclitaxel by d-α-tocopheryl polyethylene glycol 400 succinate in mice Int. J. Pharm. 359 2008 174 181
23. A. Dahan, and A. Hoffman The effect of different lipid based formulations on the oral absorption of lipophilic drugs: The ability of in vitro lipolysis and consecutive ex vivo intestinal permeability data to predict in vivo bioavailability in rats Eur. J. Pharm. Biopharm. 67 2007 96 105
24. E. Roger, F. Lagarce, E. Garcion, and J.P. Benoit Biopharmaceutical parameters to consider in order to alter the fate of nanocarriers after oral delivery Nanomedicine (London) 5 2010 287 306
25. D.M. Mudie, G.L. Amidon, and G.E. Amidon Physiological parameters for oral delivery and in vitro testing Mol. Pharm. 7 2010 1388 1405
26. A. Dahan, and A. Hoffman Evaluation of a chylomicron flow blocking approach to investigate the intestinal lymphatic transport of lipophilic drugs Eur. J. Pharm. Sci. 24 2005 381 388
27. M.L. Lind, J. Jacobsen, R. Holm, and A. Müllertz Intestinal lymphatic transport of halofantrine in rats assessed using a chylomicron flow blocking approach: the influence of polysorbate 60 and 80 Eur. J. Pharm. Sci. 35 2008 211 218
28. N.L. Trevaskis, W.N. Charman, and C.J.H. Porter Lipid based delivery systems and intestinal lymphatic drug transport: a mechanistic update Adv. Drug Deliv. Rev. 60 2008 702 716
29. Z. Zhang, F. Gao, H. Bu, J. Xiao, and Y. Li Solid lipid nanoparticles loading candesartan cilexetil enhance oral bioavailability: in vitro characteristics and absorption mechanism in rats Nanomedicine NBM 8 2012 740 747
30. R. Paliwal, S. Rai, B. Vaidya, K. Khatri, A.K. Goyal, N. Mishra, A. Mehta, and S.P. Vyas Effect of lipid core material on characteristics of solid lipid nanoparticles designed for oral lymphatic delivery Nanomedicine NBM 5 2009 184 191
31. J.A. Yáñez, S.W.J. Wang, I.W. Knemeyer, M.A. Wirth, and K.B. Alton Intestinal lymphatic transport for drug delivery Adv. Drug Deliv. Rev. 63 2011 923 942
32. A. Bargoni, R. Cavalli, O. Caputo, A. Fundaro, M.R. Gasco, and G.P. Zara Solid lipid nanoparticles in lymph and plasma after duodenal administration to rats Pharm. Res. 15 1998 745 750
33. H. Cabral, Y. Matsumoto, K. Mizuno, Q. Chen, M. Murakami, M. Kimura, Y. Terada, M.R. Kano, K. Miyazono, M. Uesaka, N. Nishiyama, and K. Kataoka Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size Nat. Nanotechnol. 6 2011 815 823