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Volumn 48, Issue , 2015, Pages 10-21

Mitochondrial dysfunction in schizophrenia: Pathways, mechanisms and implications

Author keywords

Inflammation; Mitochondria; Neuroprogression; Oxidative stress; Schizophrenia

Indexed keywords

ACETYLCYSTEINE; CALCIUM; CLOZAPINE; HALOPERIDOL; NEUROLEPTIC AGENT; REACTIVE OXYGEN METABOLITE;

EID: 84913553786     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2014.11.005     Document Type: Review
Times cited : (215)

References (193)
  • 1
    • 84890837041 scopus 로고    scopus 로고
    • Inflammation and schizophrenia: alterations in cytokine levels and perturbation in antioxidative defense systems
    • Al-Asmari A.K., Khan M.W. Inflammation and schizophrenia: alterations in cytokine levels and perturbation in antioxidative defense systems. Hum. Exp. Toxicol. 2014, 33(2):115-122.
    • (2014) Hum. Exp. Toxicol. , vol.33 , Issue.2 , pp. 115-122
    • Al-Asmari, A.K.1    Khan, M.W.2
  • 2
    • 22444441576 scopus 로고    scopus 로고
    • Deficient hippocampal neuron expression of proteasome, ubiquitin, and mitochondrial genes in multiple schizophrenia cohorts
    • Altar C.A., Jurata L.W., Charles V., Lemire A., Liu P., Bukhman Y., Brockman J.A. Deficient hippocampal neuron expression of proteasome, ubiquitin, and mitochondrial genes in multiple schizophrenia cohorts. Biol. Psychiatry 2005, 58(2):85-96.
    • (2005) Biol. Psychiatry , vol.58 , Issue.2 , pp. 85-96
    • Altar, C.A.1    Jurata, L.W.2    Charles, V.3    Lemire, A.4    Liu, P.5    Bukhman, Y.6    Brockman, J.A.7
  • 3
    • 84866349244 scopus 로고    scopus 로고
    • Chronic treatment of haloperidol induces pathological changes in striatal neurons of guinea pigs: a light and electron microscopical study?
    • Altunkaynak B.Z., Ozbek E., Unal B., Aydin N., Aydin M.D., Vuraler O. Chronic treatment of haloperidol induces pathological changes in striatal neurons of guinea pigs: a light and electron microscopical study?. Drug Chem. Toxicol. 2012, 35(4):406-411.
    • (2012) Drug Chem. Toxicol. , vol.35 , Issue.4 , pp. 406-411
    • Altunkaynak, B.Z.1    Ozbek, E.2    Unal, B.3    Aydin, N.4    Aydin, M.D.5    Vuraler, O.6
  • 4
    • 34447107744 scopus 로고    scopus 로고
    • Mitochondrial DNA HV lineage increases the susceptibility to schizophrenia among Israeli Arabs
    • Amar S., Shamir A., Ovadia O., Blanaru M., Reshef A., Kremer I., Mishmar D. Mitochondrial DNA HV lineage increases the susceptibility to schizophrenia among Israeli Arabs. Schizophr. Res. 2007, 94(1-3):354-358.
    • (2007) Schizophr. Res. , vol.94 , Issue.1-3 , pp. 354-358
    • Amar, S.1    Shamir, A.2    Ovadia, O.3    Blanaru, M.4    Reshef, A.5    Kremer, I.6    Mishmar, D.7
  • 6
    • 84873526680 scopus 로고    scopus 로고
    • Schizophrenia is primed for an increased expression of depression through activation of immuno-inflammatory, oxidative and nitrosative stress, and tryptophan catabolite pathways
    • Anderson G., Maes M., Berk M. Schizophrenia is primed for an increased expression of depression through activation of immuno-inflammatory, oxidative and nitrosative stress, and tryptophan catabolite pathways. Prog. Neuropsychopharmacol. Biol. Psychiatry 2013, 42:101-114.
    • (2013) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.42 , pp. 101-114
    • Anderson, G.1    Maes, M.2    Berk, M.3
  • 7
    • 77950575478 scopus 로고    scopus 로고
    • Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder
    • Andreazza A.C., Shao L., Wang J.F., Young L.T. Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder. Arch. Gen. Psychiatry 2010, 67:360-368.
    • (2010) Arch. Gen. Psychiatry , vol.67 , pp. 360-368
    • Andreazza, A.C.1    Shao, L.2    Wang, J.F.3    Young, L.T.4
  • 8
    • 84860594239 scopus 로고    scopus 로고
    • The psychiatric manifestations of mitochondrial disorders: a case and review of the literature
    • Anglin R.E., Garside S.L., Tarnopolsky M.A., Mazurek M.F., Rosebush P.I. The psychiatric manifestations of mitochondrial disorders: a case and review of the literature. J. Clin. Psychiatry 2012, 73(4):506-512.
    • (2012) J. Clin. Psychiatry , vol.73 , Issue.4 , pp. 506-512
    • Anglin, R.E.1    Garside, S.L.2    Tarnopolsky, M.A.3    Mazurek, M.F.4    Rosebush, P.I.5
  • 9
    • 77954457577 scopus 로고    scopus 로고
    • Minocycline chelates Ca2+, binds to membranes, and depolarizes mitochondria by formation of Ca2+-dependention channels
    • Antonenko Y.N., Rokitskaya T.I., Cooper A.J., Krasnikov B.F. Minocycline chelates Ca2+, binds to membranes, and depolarizes mitochondria by formation of Ca2+-dependention channels. J. Bioenerg. Biomembr. 2010, 42(2):151-163.
    • (2010) J. Bioenerg. Biomembr. , vol.42 , Issue.2 , pp. 151-163
    • Antonenko, Y.N.1    Rokitskaya, T.I.2    Cooper, A.J.3    Krasnikov, B.F.4
  • 10
    • 79151471696 scopus 로고    scopus 로고
    • Disrupted in Schizophrenia-1 regulates intracellular trafficking of mitochondria in neurons
    • Atkin T.A., MacAskill A.F., Brandon N.J., Kittler J.T. Disrupted in Schizophrenia-1 regulates intracellular trafficking of mitochondria in neurons. Mol. Psychiatry 2011, 16(2):122-128.
    • (2011) Mol. Psychiatry , vol.16 , Issue.2 , pp. 122-128
    • Atkin, T.A.1    MacAskill, A.F.2    Brandon, N.J.3    Kittler, J.T.4
  • 11
    • 84860179774 scopus 로고    scopus 로고
    • Is dopamine neurotransmission altered in prodromal schizophrenia? A review of the evidence
    • Bauer M., Praschak-Rieder N., Kasper S., Willeit M. Is dopamine neurotransmission altered in prodromal schizophrenia? A review of the evidence. Curr. Pharm. Des. 2012, 18:1568-1579.
    • (2012) Curr. Pharm. Des. , vol.18 , pp. 1568-1579
    • Bauer, M.1    Praschak-Rieder, N.2    Kasper, S.3    Willeit, M.4
  • 13
    • 0036902639 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in schizophrenia: a possible linkage to dopamine
    • Ben-Shachar D. Mitochondrial dysfunction in schizophrenia: a possible linkage to dopamine. J. Neurochem. 2002, 83(6):1241-1251.
    • (2002) J. Neurochem. , vol.83 , Issue.6 , pp. 1241-1251
    • Ben-Shachar, D.1
  • 14
    • 2342573633 scopus 로고    scopus 로고
    • Dopamine toxicity involves mitochondrial complex I inhibition: implications to dopamine-related neuropsychiatric disorders?
    • Ben-Shachar D., Zuk R., Gazawi H., Ljubuncic P. Dopamine toxicity involves mitochondrial complex I inhibition: implications to dopamine-related neuropsychiatric disorders?. Biochem. Pharmacol. 2004, 67(10):1965-1974.
    • (2004) Biochem. Pharmacol. , vol.67 , Issue.10 , pp. 1965-1974
    • Ben-Shachar, D.1    Zuk, R.2    Gazawi, H.3    Ljubuncic, P.4
  • 15
    • 41049092301 scopus 로고    scopus 로고
    • Sp1 expression is disrupted in schizophrenia; a possible mechanism for the abnormal expression of mitochondrial complex I genes, NDUFV1 and NDUFV2
    • Ben-Shachar D., Karry R. Sp1 expression is disrupted in schizophrenia; a possible mechanism for the abnormal expression of mitochondrial complex I genes, NDUFV1 and NDUFV2. PLoS One 2007, 2(9):e817.
    • (2007) PLoS One , vol.2 , Issue.9 , pp. e817
    • Ben-Shachar, D.1    Karry, R.2
  • 16
    • 0034640382 scopus 로고    scopus 로고
    • The specificity of platelet glutamate receptor supersensitivity in psychotic disorders?
    • Berk M., Plein H., Belsham B. The specificity of platelet glutamate receptor supersensitivity in psychotic disorders?. Life Sci. 2000, 66(25):2427-2432.
    • (2000) Life Sci. , vol.66 , Issue.25 , pp. 2427-2432
    • Berk, M.1    Plein, H.2    Belsham, B.3
  • 21
    • 0037101606 scopus 로고    scopus 로고
    • Presynaptic mitochondrial calcium sequestration influences transmission at mammalian central synapses
    • Billups B., Forsythe I.D. Presynaptic mitochondrial calcium sequestration influences transmission at mammalian central synapses. J. Neurosci. 2002, 22(14):5840-5847.
    • (2002) J. Neurosci. , vol.22 , Issue.14 , pp. 5840-5847
    • Billups, B.1    Forsythe, I.D.2
  • 22
    • 78649908751 scopus 로고    scopus 로고
    • Oxidative stress in schizophrenia: an integrated approach
    • Bitanihirwe B.K.Y., Woo T.U.W. Oxidative stress in schizophrenia: an integrated approach. Neurosci. Biobehav. Rev. 2011, 35(3):878-893.
    • (2011) Neurosci. Biobehav. Rev. , vol.35 , Issue.3 , pp. 878-893
    • Bitanihirwe, B.K.Y.1    Woo, T.U.W.2
  • 23
    • 0036357489 scopus 로고    scopus 로고
    • Glucose/Mitochondria in neurological conditions
    • Blass P. Glucose/Mitochondria in neurological conditions. Int. Rev. Neurobiol. 2002, 51:325-376.
    • (2002) Int. Rev. Neurobiol. , vol.51 , pp. 325-376
    • Blass, P.1
  • 24
    • 24144453087 scopus 로고    scopus 로고
    • Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism
    • Block M.L., Hong J.S. Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. Prog. Neurobiol. 2005, 76(2):77-98.
    • (2005) Prog. Neurobiol. , vol.76 , Issue.2 , pp. 77-98
    • Block, M.L.1    Hong, J.S.2
  • 25
    • 0027408221 scopus 로고
    • Advancing a neurodevelopmental origin for schizophrenia?
    • Bloom F.E. Advancing a neurodevelopmental origin for schizophrenia?. Arch. Gen. Psychiatry 1993, 50(3):224-227.
    • (1993) Arch. Gen. Psychiatry , vol.50 , Issue.3 , pp. 224-227
    • Bloom, F.E.1
  • 27
    • 38549125376 scopus 로고    scopus 로고
    • Dopamine modulates mitochondrial function in viable SH-SY5Y cells possibly via its interaction with complex I: relevance to dopamine pathology in schizophrenia?
    • Brenner-Lavie H., Klein E., Zuk R., Gazawi H., Ljubuncic P., Ben-Shachar D. Dopamine modulates mitochondrial function in viable SH-SY5Y cells possibly via its interaction with complex I: relevance to dopamine pathology in schizophrenia?. Biochim. Biophys. Acta 2008, 1777(2):173-185.
    • (2008) Biochim. Biophys. Acta , vol.1777 , Issue.2 , pp. 173-185
    • Brenner-Lavie, H.1    Klein, E.2    Zuk, R.3    Gazawi, H.4    Ljubuncic, P.5    Ben-Shachar, D.6
  • 28
    • 51249114495 scopus 로고    scopus 로고
    • Estrogen regulation of glucose metabolism and mitochondrial function: therapeutic implications for prevention of Alzheimer's disease
    • Brinton R.D. Estrogen regulation of glucose metabolism and mitochondrial function: therapeutic implications for prevention of Alzheimer's disease. Adv. Drug Delivery Rev. 2008, 60(13-14):1504-1511.
    • (2008) Adv. Drug Delivery Rev. , vol.60 , Issue.13-14 , pp. 1504-1511
    • Brinton, R.D.1
  • 30
    • 84862663441 scopus 로고    scopus 로고
    • Exposure to prenatal infection and risk of schizophrenia
    • Brown A.S. Exposure to prenatal infection and risk of schizophrenia. Front. Psychiatry 2011, 2:63.
    • (2011) Front. Psychiatry , vol.2 , pp. 63
    • Brown, A.S.1
  • 31
    • 34248562417 scopus 로고    scopus 로고
    • Neuroleptic treatment effect on mitochondrial electron transport chain: peripheral blood mononuclear cells analysis in psychotic patients
    • Casademont J., et al. Neuroleptic treatment effect on mitochondrial electron transport chain: peripheral blood mononuclear cells analysis in psychotic patients. J. Clin. Psychopharmacol. 2007, 27:284-288.
    • (2007) J. Clin. Psychopharmacol. , vol.27 , pp. 284-288
    • Casademont, J.1
  • 32
    • 0029101854 scopus 로고
    • Decreased cytochrome c oxidase activity and lack of age related accumulation of mtDNA in brain of schizophrenics
    • Cavelier L., Jazin E., Eriksson I., Prince J., Bave U., Oreland L., et al. Decreased cytochrome c oxidase activity and lack of age related accumulation of mtDNA in brain of schizophrenics. Genomics 1995, 29:217-228.
    • (1995) Genomics , vol.29 , pp. 217-228
    • Cavelier, L.1    Jazin, E.2    Eriksson, I.3    Prince, J.4    Bave, U.5    Oreland, L.6
  • 33
    • 84873557177 scopus 로고    scopus 로고
    • Cadmium induces apoptosis in pancreatic β-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation
    • Chang K.C., Hsu C.C., Liu S.H., Su C.C., Yen C.C., Lee M.J., Chen K.L., Ho T.J., Hung D.Z., Wu C.C., Lu T.H., Su Y.C., Chen Y.W., Huang C.F. Cadmium induces apoptosis in pancreatic β-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation. PLoS One 2013, 8(2):e54374.
    • (2013) PLoS One , vol.8 , Issue.2 , pp. e54374
    • Chang, K.C.1    Hsu, C.C.2    Liu, S.H.3    Su, C.C.4    Yen, C.C.5    Lee, M.J.6    Chen, K.L.7    Ho, T.J.8    Hung, D.Z.9    Wu, C.C.10    Lu, T.H.11    Su, Y.C.12    Chen, Y.W.13    Huang, C.F.14
  • 35
    • 84864999825 scopus 로고    scopus 로고
    • Minocycline benefits negative symptoms in early schizophrenia: a randomised double-blind placebo-controlled clinical trial in patients on standard treatment
    • Chaudhry I.B., Hallak J., Husain N., et al. Minocycline benefits negative symptoms in early schizophrenia: a randomised double-blind placebo-controlled clinical trial in patients on standard treatment. J. Psychopharmacol. 2012, 26:1185-1193.
    • (2012) J. Psychopharmacol. , vol.26 , pp. 1185-1193
    • Chaudhry, I.B.1    Hallak, J.2    Husain, N.3
  • 36
    • 84871132239 scopus 로고    scopus 로고
    • Chloroacetic acid induced neuronal cells death through oxidative stress-mediated p38-MAPK activation pathway regulated mitochondria-dependent apoptotic signals
    • Chen C.H., Chen S.J., Su C.C., Yen C.C., Tseng T.J., Jinn T.R., Tang F.C., Chen K.L., Su Y.C., Lee K.I., Hung D.Z., Huang C.F. Chloroacetic acid induced neuronal cells death through oxidative stress-mediated p38-MAPK activation pathway regulated mitochondria-dependent apoptotic signals. Toxicology 2013, 303:72-82.
    • (2013) Toxicology , vol.303 , pp. 72-82
    • Chen, C.H.1    Chen, S.J.2    Su, C.C.3    Yen, C.C.4    Tseng, T.J.5    Jinn, T.R.6    Tang, F.C.7    Chen, K.L.8    Su, Y.C.9    Lee, K.I.10    Hung, D.Z.11    Huang, C.F.12
  • 37
    • 0037455575 scopus 로고    scopus 로고
    • Mitofusins Mfn1 and Mfn2 co-ordinately regulate mitochondrial fusion and are essential for embryonic development
    • 20
    • Chen H., Detmer S.A., Ewald A.J., Griffin E.E., Fraser S.E., Chan D.C. Mitofusins Mfn1 and Mfn2 co-ordinately regulate mitochondrial fusion and are essential for embryonic development. J. Cell Biol. 2003, 160(2):189-200. 20.
    • (2003) J. Cell Biol. , vol.160 , Issue.2 , pp. 189-200
    • Chen, H.1    Detmer, S.A.2    Ewald, A.J.3    Griffin, E.E.4    Fraser, S.E.5    Chan, D.C.6
  • 38
    • 78650071220 scopus 로고    scopus 로고
    • Mitochondria and neuroplasticity
    • Cheng A., Hou Y., Mattson M.P. Mitochondria and neuroplasticity. ASN Neuro 2010, 2(5):e00045.
    • (2010) ASN Neuro , vol.2 , Issue.5 , pp. e00045
    • Cheng, A.1    Hou, Y.2    Mattson, M.P.3
  • 39
    • 80051964405 scopus 로고    scopus 로고
    • Genetic association studies of antioxidant pathway genes and schizophrenia
    • Chowdari K.W., Bamne M.N., Nimgaonkar V.L. Genetic association studies of antioxidant pathway genes and schizophrenia. Antioxid. Redox Signaling 2011, 15:2037-2045.
    • (2011) Antioxid. Redox Signaling , vol.15 , pp. 2037-2045
    • Chowdari, K.W.1    Bamne, M.N.2    Nimgaonkar, V.L.3
  • 41
    • 33846862899 scopus 로고    scopus 로고
    • Neurodegeneration in schizophrenia: evidence from in vivo neuroimaging studies
    • Csernansky J.G. Neurodegeneration in schizophrenia: evidence from in vivo neuroimaging studies. Sci. World J. 2007, 2(7):135-143.
    • (2007) Sci. World J. , vol.2 , Issue.7 , pp. 135-143
    • Csernansky, J.G.1
  • 42
    • 84903534875 scopus 로고    scopus 로고
    • Neuroprogression in schizophrenia: pathways underpinning clinical staging and therapeutic corollaries
    • Davis J., Moylan S., Harvey B.H., Maes M., Berk M. Neuroprogression in schizophrenia: pathways underpinning clinical staging and therapeutic corollaries. Aust. N.Z. J. Psychiatry 2014, 48(6):512-529.
    • (2014) Aust. N.Z. J. Psychiatry , vol.48 , Issue.6 , pp. 512-529
    • Davis, J.1    Moylan, S.2    Harvey, B.H.3    Maes, M.4    Berk, M.5
  • 45
    • 84901502236 scopus 로고    scopus 로고
    • Th17 pathway-mediated immunopathogenesis of schizophrenia: mechanisms and implications
    • Debnath M., Berk M. Th17 pathway-mediated immunopathogenesis of schizophrenia: mechanisms and implications. Schizophr Bull. 2014, 40(6):1412-1421.
    • (2014) Schizophr Bull. , vol.40 , Issue.6 , pp. 1412-1421
    • Debnath, M.1    Berk, M.2
  • 46
    • 40049097816 scopus 로고    scopus 로고
    • The concept of progressive brain change in schizophrenia: implications for understanding schizophrenia
    • DeLisi L.E. The concept of progressive brain change in schizophrenia: implications for understanding schizophrenia. Schizophr. Bull. 2008, 34:312-321.
    • (2008) Schizophr. Bull. , vol.34 , pp. 312-321
    • DeLisi, L.E.1
  • 48
    • 0036430378 scopus 로고    scopus 로고
    • State-dependent alterations in mitochondrial complex I activity in platelets: a potential peripheral marker for schizophrenia?
    • Dror N., Klein E., Karry R., Sheinkman A., Kirsh Z., Mazor M., Tzukerman M., Ben-Shachar D. State-dependent alterations in mitochondrial complex I activity in platelets: a potential peripheral marker for schizophrenia?. Mol. Psychiatry 2002, 7(9):995-1001.
    • (2002) Mol. Psychiatry , vol.7 , Issue.9 , pp. 995-1001
    • Dror, N.1    Klein, E.2    Karry, R.3    Sheinkman, A.4    Kirsh, Z.5    Mazor, M.6    Tzukerman, M.7    Ben-Shachar, D.8
  • 49
    • 34548806900 scopus 로고    scopus 로고
    • Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain
    • Duan X., Chang J.H., Ge S., Faulkner R.L., Kim J.Y., Kitabatake Y., Song H. Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain. Cell 2007, 130(6):1146-1158.
    • (2007) Cell , vol.130 , Issue.6 , pp. 1146-1158
    • Duan, X.1    Chang, J.H.2    Ge, S.3    Faulkner, R.L.4    Kim, J.Y.5    Kitabatake, Y.6    Song, H.7
  • 50
    • 4043086952 scopus 로고    scopus 로고
    • Mitochondria in health and disease: perspectives on a new mitochondrial biology
    • Duchen M.R. Mitochondria in health and disease: perspectives on a new mitochondrial biology. Mol. Aspects Med. 2004, 25:365-451.
    • (2004) Mol. Aspects Med. , vol.25 , pp. 365-451
    • Duchen, M.R.1
  • 52
    • 84864501555 scopus 로고    scopus 로고
    • A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins
    • Eykelenboom J.E., Briggs G.J., Bradshaw N.J., Soares D.C., Ogawa F., Christie S., et al. A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins. Hum. Mol. Genet. 2012, 21(15):3374-3386.
    • (2012) Hum. Mol. Genet. , vol.21 , Issue.15 , pp. 3374-3386
    • Eykelenboom, J.E.1    Briggs, G.J.2    Bradshaw, N.J.3    Soares, D.C.4    Ogawa, F.5    Christie, S.6
  • 53
    • 84894600418 scopus 로고    scopus 로고
    • Schizophrenia induces oxidative stress and cytochrome C release in isolated rat brain mitochondria: a possible pathway for induction of apoptosis and neurodegeneration
    • Faizi M., Salimi A., Rasoulzadeh M., Naserzadeh P., Pourahmad J. Schizophrenia induces oxidative stress and cytochrome C release in isolated rat brain mitochondria: a possible pathway for induction of apoptosis and neurodegeneration. Iran J. Pharm. Res. 2014, 13(Suppl):93-100.
    • (2014) Iran J. Pharm. Res. , vol.13 , Issue.SUPPL , pp. 93-100
    • Faizi, M.1    Salimi, A.2    Rasoulzadeh, M.3    Naserzadeh, P.4    Pourahmad, J.5
  • 54
    • 79953308141 scopus 로고    scopus 로고
    • Synaptic changes in the brain of subjects with schizophrenia
    • Faludi G., Mirnics K. Synaptic changes in the brain of subjects with schizophrenia. Int. J. Dev. Neurosci. 2011, 29(3):305-309.
    • (2011) Int. J. Dev. Neurosci. , vol.29 , Issue.3 , pp. 305-309
    • Faludi, G.1    Mirnics, K.2
  • 57
    • 79952621642 scopus 로고    scopus 로고
    • Aberrant tyrosine transport across the fibroblast membrane in patients with schizophrenia-indications of maternal inheritance?
    • Flyckt L., Edman G., Venizelos N., Borg K. Aberrant tyrosine transport across the fibroblast membrane in patients with schizophrenia-indications of maternal inheritance?. J. Psychiatr. Res. 2011, 45(4):519-525.
    • (2011) J. Psychiatr. Res. , vol.45 , Issue.4 , pp. 519-525
    • Flyckt, L.1    Edman, G.2    Venizelos, N.3    Borg, K.4
  • 58
    • 44649100090 scopus 로고    scopus 로고
    • Quantitative analysis of the 4977-bp common deletion of mitochondrial DNA in postmortem frontal cortex from patients with bipolar disorder and schizophrenia
    • Fuke S., Kametani M., Kato T. Quantitative analysis of the 4977-bp common deletion of mitochondrial DNA in postmortem frontal cortex from patients with bipolar disorder and schizophrenia. Neurosci. Lett. 2008, 439:173-177.
    • (2008) Neurosci. Lett. , vol.439 , pp. 173-177
    • Fuke, S.1    Kametani, M.2    Kato, T.3
  • 59
    • 71849095133 scopus 로고    scopus 로고
    • Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases
    • Gibson G.E., Starkov A., Blass J.P., Ratan R.R., Beal M.F. Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases. Biochim. Biophys. Acta 2010, 1802(1):122-134.
    • (2010) Biochim. Biophys. Acta , vol.1802 , Issue.1 , pp. 122-134
    • Gibson, G.E.1    Starkov, A.2    Blass, J.P.3    Ratan, R.R.4    Beal, M.F.5
  • 60
    • 84885661909 scopus 로고    scopus 로고
    • Gestational exposure to a viral mimetic poly(i:c) results in long-lasting changes in mitochondrial function by leucocytes in the adult offspring
    • 609602
    • Giulivi C., Napoli E., Schwartzer J., Careaga M., Ashwood P. Gestational exposure to a viral mimetic poly(i:c) results in long-lasting changes in mitochondrial function by leucocytes in the adult offspring. Mediators Inflamm. 2013, 609602:8.
    • (2013) Mediators Inflamm. , pp. 8
    • Giulivi, C.1    Napoli, E.2    Schwartzer, J.3    Careaga, M.4    Ashwood, P.5
  • 62
    • 84900793184 scopus 로고    scopus 로고
    • A hypothesis-driven association study of 28 nuclear-encoded mitochondrial genes with antipsychotic-induced weight gain in schizophrenia
    • Gonçalves V.F., Zai C.C., Tiwari A.K., Brandl E.J., Derkach A., Meltzer H.Y., et al. A hypothesis-driven association study of 28 nuclear-encoded mitochondrial genes with antipsychotic-induced weight gain in schizophrenia. Neuropsychopharmacology 2014, 39:1347-1354.
    • (2014) Neuropsychopharmacology , vol.39 , pp. 1347-1354
    • Gonçalves, V.F.1    Zai, C.C.2    Tiwari, A.K.3    Brandl, E.J.4    Derkach, A.5    Meltzer, H.Y.6
  • 63
    • 84881557425 scopus 로고    scopus 로고
    • Mitochondrial activity and oxidative stress markers in peripheral blood mononuclear cells of patients with bipolar disorder, schizophrenia, and healthy subjects
    • Gubert C., Stertz L., Pfaffenseller B., Panizzutti B.S., Rezin G.T., Massuda R., et al. Mitochondrial activity and oxidative stress markers in peripheral blood mononuclear cells of patients with bipolar disorder, schizophrenia, and healthy subjects. J. Psychiatr. Res. 2013, 47(10):1396-1402.
    • (2013) J. Psychiatr. Res. , vol.47 , Issue.10 , pp. 1396-1402
    • Gubert, C.1    Stertz, L.2    Pfaffenseller, B.3    Panizzutti, B.S.4    Rezin, G.T.5    Massuda, R.6
  • 64
    • 84892517669 scopus 로고    scopus 로고
    • Mitochondria: hub of injury responses in the developing brain
    • Hagberg H., Mallard C., Rousset C.I., Thronton C. Mitochondria: hub of injury responses in the developing brain. Lancet Neurol. 2014, 13(2):217-232.
    • (2014) Lancet Neurol. , vol.13 , Issue.2 , pp. 217-232
    • Hagberg, H.1    Mallard, C.2    Rousset, C.I.3    Thronton, C.4
  • 66
    • 33745662190 scopus 로고    scopus 로고
    • Reactive species and antioxidants. redox biology is a fundamental theme of aerobic life
    • Halliwell B. Reactive species and antioxidants. redox biology is a fundamental theme of aerobic life. Plant Physiol. 2006, 141:312-322.
    • (2006) Plant Physiol. , vol.141 , pp. 312-322
    • Halliwell, B.1
  • 67
    • 12344327212 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence
    • Harrison P.J., Weinberger D.R. Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol. Psychiatry 2005, 10:40-68.
    • (2005) Mol. Psychiatry , vol.10 , pp. 40-68
    • Harrison, P.J.1    Weinberger, D.R.2
  • 68
    • 0028094864 scopus 로고
    • Identification of catechol-protein conjugates in neostriatal slices incubated with [3H] dopamine: impact of ascorbic acid and glutathione
    • Hastings T.G., Zigmond M.J. Identification of catechol-protein conjugates in neostriatal slices incubated with [3H] dopamine: impact of ascorbic acid and glutathione. J. Neurochem. 1994, 63:1126-1132.
    • (1994) J. Neurochem. , vol.63 , pp. 1126-1132
    • Hastings, T.G.1    Zigmond, M.J.2
  • 69
    • 65349120160 scopus 로고    scopus 로고
    • The dopamine hypothesis of schizophrenia: Version III-The final common pathway
    • Howes O.D., Kapur S. The dopamine hypothesis of schizophrenia: Version III-The final common pathway. Schizophr. Bull. 2009, 35(3):549-562.
    • (2009) Schizophr. Bull. , vol.35 , Issue.3 , pp. 549-562
    • Howes, O.D.1    Kapur, S.2
  • 70
    • 84901614656 scopus 로고    scopus 로고
    • Recent mitochondrial DNA mutations increase the risk of developing common late-onset human diseases
    • Hudson G., Gomez-Duran A., Wilson I.J., Chinnery P.F. Recent mitochondrial DNA mutations increase the risk of developing common late-onset human diseases. PLoS Genet. 2014, 10(5):e1004369.
    • (2014) PLoS Genet. , vol.10 , Issue.5 , pp. e1004369
    • Hudson, G.1    Gomez-Duran, A.2    Wilson, I.J.3    Chinnery, P.F.4
  • 71
    • 40049102475 scopus 로고    scopus 로고
    • What happens after the first episode? A review of progressive brain changes in chronically ill patients with schizophrenia
    • Hulshoff Pol H.E., Kahn R.S. What happens after the first episode? A review of progressive brain changes in chronically ill patients with schizophrenia. Schizophr. Bull. 2008, 34:354-366.
    • (2008) Schizophr. Bull. , vol.34 , pp. 354-366
    • Hulshoff Pol, H.E.1    Kahn, R.S.2
  • 73
    • 0028854722 scopus 로고
    • Point mutations of the mitochondrial genome in Parkinson's disease
    • Ikebe S., Tanaka M., Ozawa T. Point mutations of the mitochondrial genome in Parkinson's disease. Mol. Brain Res. 1995, 28:281-295.
    • (1995) Mol. Brain Res. , vol.28 , pp. 281-295
    • Ikebe, S.1    Tanaka, M.2    Ozawa, T.3
  • 74
    • 78149428430 scopus 로고    scopus 로고
    • Rethinking schizophrenia
    • Insel T.R. Rethinking schizophrenia. Nature 2010, 468(7321):187-193.
    • (2010) Nature , vol.468 , Issue.7321 , pp. 187-193
    • Insel, T.R.1
  • 75
    • 29044441978 scopus 로고    scopus 로고
    • QSAR modeling and transmission electron microscopy stereology of altered mitochondrial ultrastructure of white blood cells in patients diagnosed as schizophrenic and treated with antipsychotic drugs
    • Inuwa I.M., Peet M., Williams M.A. QSAR modeling and transmission electron microscopy stereology of altered mitochondrial ultrastructure of white blood cells in patients diagnosed as schizophrenic and treated with antipsychotic drugs. Biotech. Histochem. 2005, 80:133-137.
    • (2005) Biotech. Histochem. , vol.80 , pp. 133-137
    • Inuwa, I.M.1    Peet, M.2    Williams, M.A.3
  • 76
    • 68249087424 scopus 로고    scopus 로고
    • Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
    • Ishihara N., Nomura M., Jofuku A., Kato H., Suzuki S.O., Masuda K., et al. Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice. Nat. Cell Biol. 2009, 11:958-966.
    • (2009) Nat. Cell Biol. , vol.11 , pp. 958-966
    • Ishihara, N.1    Nomura, M.2    Jofuku, A.3    Kato, H.4    Suzuki, S.O.5    Masuda, K.6
  • 77
    • 12744278205 scopus 로고    scopus 로고
    • Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis
    • Iwamoto K., Bundo M., Kato T. Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis. Hum. Mol. Genet. 2005, 14(2):241-253.
    • (2005) Hum. Mol. Genet. , vol.14 , Issue.2 , pp. 241-253
    • Iwamoto, K.1    Bundo, M.2    Kato, T.3
  • 78
    • 84870060837 scopus 로고    scopus 로고
    • Promoter polymorphisms in two overlapping 6p25 genes implicate mitochondrial proteins in cognitive deficit in schizophrenia
    • Jablensky A., Angelicheva D., Donohoe G.J., Cruickshank M., Azmanov D.N., Morris D.W., et al. Promoter polymorphisms in two overlapping 6p25 genes implicate mitochondrial proteins in cognitive deficit in schizophrenia. Mol. Psychiatry 2012, 17(12):1328-1339.
    • (2012) Mol. Psychiatry , vol.17 , Issue.12 , pp. 1328-1339
    • Jablensky, A.1    Angelicheva, D.2    Donohoe, G.J.3    Cruickshank, M.4    Azmanov, D.N.5    Morris, D.W.6
  • 79
    • 2342539835 scopus 로고    scopus 로고
    • Disrupted in Schizophrenia 1 (DISC1) is a multicompartmentalized protein that predominantly localizes to mitochondria
    • James R., Adams R.R., Christie S., Buchanan S.R., Porteous D.J., Millar J.K. Disrupted in Schizophrenia 1 (DISC1) is a multicompartmentalized protein that predominantly localizes to mitochondria. Mol. Cell. Neurosci. 2004, 26:112-122.
    • (2004) Mol. Cell. Neurosci. , vol.26 , pp. 112-122
    • James, R.1    Adams, R.R.2    Christie, S.3    Buchanan, S.R.4    Porteous, D.J.5    Millar, J.K.6
  • 80
    • 84884681926 scopus 로고    scopus 로고
    • Convergence of genetic and environmental factors on parvalbumin-positive interneurons in schizophrenia
    • Jiang Z., Cowell R.M., Nakazawa K. Convergence of genetic and environmental factors on parvalbumin-positive interneurons in schizophrenia. Front. Behav. Neurosci. 2013, 3(7):116.
    • (2013) Front. Behav. Neurosci. , vol.3 , Issue.7 , pp. 116
    • Jiang, Z.1    Cowell, R.M.2    Nakazawa, K.3
  • 81
    • 84905907161 scopus 로고    scopus 로고
    • Perinatal protein malnutrition affects mitochondrial function in adult and results in a resistance to high fat diet-induced obesity
    • Jousse C., Muranishi Y., Parry L., Montaurier C., Even P., Launay J.M., et al. Perinatal protein malnutrition affects mitochondrial function in adult and results in a resistance to high fat diet-induced obesity. PLoS One 2014, 13(9(8)):e104896.
    • (2014) PLoS One , vol.13 , Issue.8-9 , pp. e104896
    • Jousse, C.1    Muranishi, Y.2    Parry, L.3    Montaurier, C.4    Even, P.5    Launay, J.M.6
  • 82
    • 0034927814 scopus 로고    scopus 로고
    • Apoptotic signaling in dopamine-induced cell death: the role of oxidative stress, p38 mitogen activated protein kinase, cytochrome c and caspases
    • Junn E., Mouradian M.M. Apoptotic signaling in dopamine-induced cell death: the role of oxidative stress, p38 mitogen activated protein kinase, cytochrome c and caspases. J. Neurochem. 2001, 78(2):374-383.
    • (2001) J. Neurochem. , vol.78 , Issue.2 , pp. 374-383
    • Junn, E.1    Mouradian, M.M.2
  • 84
    • 1642352614 scopus 로고    scopus 로고
    • Mitochondrial complex I subunits expression is altered in schizophrenia: a postmortem study
    • Karry R., Klein E., Ben Shachar D. Mitochondrial complex I subunits expression is altered in schizophrenia: a postmortem study. Biol. Psychiatry 2004, 55(7):676-684.
    • (2004) Biol. Psychiatry , vol.55 , Issue.7 , pp. 676-684
    • Karry, R.1    Klein, E.2    Ben Shachar, D.3
  • 85
    • 84876696944 scopus 로고    scopus 로고
    • Minocycline mediated mitochondrial cytoprotection: premises for therapy of cerebrovascular and neurodegenerative diseases?
    • Karachitos A., García Del Pozo J.S., de Groot P.W., Kmita H., Jordán J. Minocycline mediated mitochondrial cytoprotection: premises for therapy of cerebrovascular and neurodegenerative diseases?. Curr. Drug Targets 2013, 14(1):47-55.
    • (2013) Curr. Drug Targets , vol.14 , Issue.1 , pp. 47-55
    • Karachitos, A.1    García Del Pozo, J.S.2    de Groot, P.W.3    Kmita, H.4    Jordán, J.5
  • 86
    • 0034104902 scopus 로고    scopus 로고
    • Regional differences in cerebral glucose metabolism in cirrhotic patients with subclinical hepatic encephalopathy using positron emission tomography
    • Kato A., Suzuki K., Kaneta H., Obara H., Fujishima Y., Sato S. Regional differences in cerebral glucose metabolism in cirrhotic patients with subclinical hepatic encephalopathy using positron emission tomography. Hepatol. Res. 2000, 17(3):237-245.
    • (2000) Hepatol. Res. , vol.17 , Issue.3 , pp. 237-245
    • Kato, A.1    Suzuki, K.2    Kaneta, H.3    Obara, H.4    Fujishima, Y.5    Sato, S.6
  • 87
    • 81955168013 scopus 로고    scopus 로고
    • Adjunct minocycline to clozapine treated patients with persistent schizophrenia symptoms
    • Kelly D.L., Vyas G., Richardson C.M., et al. Adjunct minocycline to clozapine treated patients with persistent schizophrenia symptoms. Schizophr. Res. 2011, 133:257-258.
    • (2011) Schizophr. Res. , vol.133 , pp. 257-258
    • Kelly, D.L.1    Vyas, G.2    Richardson, C.M.3
  • 88
  • 90
    • 77950825033 scopus 로고    scopus 로고
    • Ultrastructural abnormalities of astrocytes in the hippocampus in schizophrenia and duration of illness: a postortem morphometric study
    • Kolomeets N.S., Uranova N. Ultrastructural abnormalities of astrocytes in the hippocampus in schizophrenia and duration of illness: a postortem morphometric study. World J. Biol. Psychiatry 2010, 11(2):282-292.
    • (2010) World J. Biol. Psychiatry , vol.11 , Issue.2 , pp. 282-292
    • Kolomeets, N.S.1    Uranova, N.2
  • 92
    • 0032953266 scopus 로고    scopus 로고
    • Mitochondrial pathology in human schizophrenic striatum: a postmortem
    • Kung L., Roberts R.C. Mitochondrial pathology in human schizophrenic striatum: a postmortem. Synapse 1999, 31:67-75.
    • (1999) Synapse , vol.31 , pp. 67-75
    • Kung, L.1    Roberts, R.C.2
  • 93
    • 45549098188 scopus 로고    scopus 로고
    • Evidence implicating the candidate schizophrenia/bipolar disorder susceptibility gene G72 in mitochondrial function
    • Kvajo M., Dhilla A., Swor D.E., Karayiorgou M., Gogos J.A. Evidence implicating the candidate schizophrenia/bipolar disorder susceptibility gene G72 in mitochondrial function. Mol. Psychiatry 2008, 13(7):685-696.
    • (2008) Mol. Psychiatry , vol.13 , Issue.7 , pp. 685-696
    • Kvajo, M.1    Dhilla, A.2    Swor, D.E.3    Karayiorgou, M.4    Gogos, J.A.5
  • 95
    • 46349097952 scopus 로고    scopus 로고
    • Recent progress in elucidating the molecular mechanism of the mitochondrial permeability transition pore
    • Leung A.W., Halestrap A.P. Recent progress in elucidating the molecular mechanism of the mitochondrial permeability transition pore. Biochim. Biophys. Acta 2008, 1777(7-8):946-952.
    • (2008) Biochim. Biophys. Acta , vol.1777 , Issue.7-8 , pp. 946-952
    • Leung, A.W.1    Halestrap, A.P.2
  • 96
    • 0038381516 scopus 로고    scopus 로고
    • Mitochondrial regulation of synaptic plasticity in the hippocampus
    • Levy M., Faas G.C., Saggau P., Craigen W.J., Sweatt J.D. Mitochondrial regulation of synaptic plasticity in the hippocampus. J. Biol. Chem. 2003, 278(20):17727-17734.
    • (2003) J. Biol. Chem. , vol.278 , Issue.20 , pp. 17727-17734
    • Levy, M.1    Faas, G.C.2    Saggau, P.3    Craigen, W.J.4    Sweatt, J.D.5
  • 97
    • 36048955116 scopus 로고    scopus 로고
    • Age-specific familial risks of psychotic disorders and schizophrenia: a nation-wide epidemiological study from Sweden
    • Li X., Sundquist J., Sundquist K. Age-specific familial risks of psychotic disorders and schizophrenia: a nation-wide epidemiological study from Sweden. Schizophr. Res. 2007, 97:43-50.
    • (2007) Schizophr. Res. , vol.97 , pp. 43-50
    • Li, X.1    Sundquist, J.2    Sundquist, K.3
  • 98
    • 10944269186 scopus 로고    scopus 로고
    • The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses
    • Li Z., Okamoto K., Hayashi Y., Sheng M. The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell 2004, 119:873-887.
    • (2004) Cell , vol.119 , pp. 873-887
    • Li, Z.1    Okamoto, K.2    Hayashi, Y.3    Sheng, M.4
  • 99
    • 0032821589 scopus 로고    scopus 로고
    • Is schizophrenia a neurodegenerative disorder? A clinical and neurobiological perspective
    • Lieberman J.A. Is schizophrenia a neurodegenerative disorder? A clinical and neurobiological perspective. Biol. Psychiatry 1999, 46(6):729-739.
    • (1999) Biol. Psychiatry , vol.46 , Issue.6 , pp. 729-739
    • Lieberman, J.A.1
  • 100
    • 0029805949 scopus 로고    scopus 로고
    • Immobilization stress causes oxidative damage to lipid, protein, and DNA in the brain of rats
    • Liu J., Wang X., Shigenaga M.K., Yeo H.C., Mori A., Ames B.N. Immobilization stress causes oxidative damage to lipid, protein, and DNA in the brain of rats. FASEB J. 1996, 10:1532-1538.
    • (1996) FASEB J. , vol.10 , pp. 1532-1538
    • Liu, J.1    Wang, X.2    Shigenaga, M.K.3    Yeo, H.C.4    Mori, A.5    Ames, B.N.6
  • 101
    • 34447645974 scopus 로고
    • The lactic acid and glutathione content of the blood of schizophrenic patients
    • Looney J., Childs H. The lactic acid and glutathione content of the blood of schizophrenic patients. J. Clin. Invest. 1934, 13:963-968.
    • (1934) J. Clin. Invest. , vol.13 , pp. 963-968
    • Looney, J.1    Childs, H.2
  • 103
    • 64649093169 scopus 로고    scopus 로고
    • Mitochondrial dynamics and Neurodegeneration
    • Lu B. Mitochondrial dynamics and Neurodegeneration. Curr. Neurol. Neurosci. Rep. 2009, 9:212-219.
    • (2009) Curr. Neurol. Neurosci. Rep. , vol.9 , pp. 212-219
    • Lu, B.1
  • 104
    • 60149097713 scopus 로고    scopus 로고
    • GTPase dependent recruitment of Grif-1 by Miro1 regulates mitochondrial trafficking in hippocampal neurons
    • MacAskill A.F., Brickley K., Stephenson F.A., Kittler J.T. GTPase dependent recruitment of Grif-1 by Miro1 regulates mitochondrial trafficking in hippocampal neurons. Mol. Cell. Neurosci. 2009, 40:301-312.
    • (2009) Mol. Cell. Neurosci. , vol.40 , pp. 301-312
    • MacAskill, A.F.1    Brickley, K.2    Stephenson, F.A.3    Kittler, J.T.4
  • 106
    • 62149083806 scopus 로고    scopus 로고
    • DISC1 regulates neural progenitor proliferation via modulation of GSK3β/β-catenin signaling
    • Mao Y., Ge X., Frank C.L., Madison J.M., Angela N., Doud M.K., et al. DISC1 regulates neural progenitor proliferation via modulation of GSK3β/β-catenin signaling. Cell 2009, 136:1017-1031.
    • (2009) Cell , vol.136 , pp. 1017-1031
    • Mao, Y.1    Ge, X.2    Frank, C.L.3    Madison, J.M.4    Angela, N.5    Doud, M.K.6
  • 111
  • 114
    • 0029826376 scopus 로고    scopus 로고
    • Dopamine induces apoptotic cell death of a catecholaminergic cell line derived from the central nervous system
    • Masserano J.M., Gong L., Kulaga H., Baker I., Wyatt R.J. Dopamine induces apoptotic cell death of a catecholaminergic cell line derived from the central nervous system. Mol. Pharmacol. 1996, 50:1309-1315.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 1309-1315
    • Masserano, J.M.1    Gong, L.2    Kulaga, H.3    Baker, I.4    Wyatt, R.J.5
  • 115
    • 0033119576 scopus 로고    scopus 로고
    • Evidence for mitochondrial control of neuronal polarity
    • Mattson M.P., Partin J. Evidence for mitochondrial control of neuronal polarity. J. Neurosci. Res. 1999, 56:8-20.
    • (1999) J. Neurosci. Res. , vol.56 , pp. 8-20
    • Mattson, M.P.1    Partin, J.2
  • 116
    • 57049143140 scopus 로고    scopus 로고
    • Mitochondria in neuroplasticity and neurological disorders
    • Mattson M.P., Gleichmann M., Cheng A. Mitochondria in neuroplasticity and neurological disorders. Neuron 2008, 60:748-766.
    • (2008) Neuron , vol.60 , pp. 748-766
    • Mattson, M.P.1    Gleichmann, M.2    Cheng, A.3
  • 117
    • 0035280535 scopus 로고    scopus 로고
    • Evidence for a mitochondrial oxidative phosphorylation defect in brains from patients with schizophrenia
    • Maurer I., Zierz S., Möller H. Evidence for a mitochondrial oxidative phosphorylation defect in brains from patients with schizophrenia. Schizophr. Res. 2001, 48:125-136.
    • (2001) Schizophr. Res. , vol.48 , pp. 125-136
    • Maurer, I.1    Zierz, S.2    Möller, H.3
  • 118
    • 0021277402 scopus 로고
    • The Chestnut Lodge follow-up study. II. Long-term outcome of schizophrenia and the affective disorders
    • McGlashan T.H. The Chestnut Lodge follow-up study. II. Long-term outcome of schizophrenia and the affective disorders. Arch. Gen. Psychiatry 1984, 41:586-601.
    • (1984) Arch. Gen. Psychiatry , vol.41 , pp. 586-601
    • McGlashan, T.H.1
  • 119
    • 0033936744 scopus 로고    scopus 로고
    • Schizophrenia as a disorder of developmentally reduced synaptic connectivity?
    • McGlashan T.H., Hoffman R.E. Schizophrenia as a disorder of developmentally reduced synaptic connectivity?. Arch. Gen. Psychiatry 2000, 57(7):637-648.
    • (2000) Arch. Gen. Psychiatry , vol.57 , Issue.7 , pp. 637-648
    • McGlashan, T.H.1    Hoffman, R.E.2
  • 120
    • 0036092524 scopus 로고    scopus 로고
    • Mitochondrial Ca(2+) buffering regulates synaptic transmission between retinal amacrine cells
    • Medler K., Gleason E.L. Mitochondrial Ca(2+) buffering regulates synaptic transmission between retinal amacrine cells. J. Neurophysiol. 2002, 87:1426-1439.
    • (2002) J. Neurophysiol. , vol.87 , pp. 1426-1439
    • Medler, K.1    Gleason, E.L.2
  • 122
    • 84873522724 scopus 로고    scopus 로고
    • Developmental neuroinflammation and schizophrenia
    • Meyer U. Developmental neuroinflammation and schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry 2013, 5(42):20-34.
    • (2013) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.5 , Issue.42 , pp. 20-34
    • Meyer, U.1
  • 123
    • 28344457312 scopus 로고    scopus 로고
    • Disrupted in schizophrenia 1 (DISC1): subcellular targeting and induction of ring mitochondria
    • Millar J.K., James R., Christie S., Porteous D.J. Disrupted in schizophrenia 1 (DISC1): subcellular targeting and induction of ring mitochondria. Mol. Cell. Neurosci. 2005, 30(4):477-484.
    • (2005) Mol. Cell. Neurosci. , vol.30 , Issue.4 , pp. 477-484
    • Millar, J.K.1    James, R.2    Christie, S.3    Porteous, D.J.4
  • 124
    • 3042550340 scopus 로고    scopus 로고
    • Differential effects of typical and atypical neuroleptics on mitochondrial function in vitro
    • Modica-Napolitano J.S., Lagace C.J., Brennan W.A., Aprille J.R. Differential effects of typical and atypical neuroleptics on mitochondrial function in vitro. Arch. Pharm. Res. 2003, 26:951-959.
    • (2003) Arch. Pharm. Res. , vol.26 , pp. 951-959
    • Modica-Napolitano, J.S.1    Lagace, C.J.2    Brennan, W.A.3    Aprille, J.R.4
  • 125
    • 84856120944 scopus 로고    scopus 로고
    • From the revolution to evolution: the glutamate hypothesis of schizophrenia and its impliication for treatment
    • Moghaddam B., Javitt D. From the revolution to evolution: the glutamate hypothesis of schizophrenia and its impliication for treatment. Neuropsychopharmacology 2012, 37(1):4-15.
    • (2012) Neuropsychopharmacology , vol.37 , Issue.1 , pp. 4-15
    • Moghaddam, B.1    Javitt, D.2
  • 126
    • 84887256413 scopus 로고    scopus 로고
    • N-acetyl cysteine reverses social isolation rearing induced changes in cortico-striatal monoamines in rats
    • Möller M., Du Preez J.L., Viljoen F.P., Berk M., Harvey B.H. N-acetyl cysteine reverses social isolation rearing induced changes in cortico-striatal monoamines in rats. Metab. Brain Dis. 2013, 28(4):687-696.
    • (2013) Metab. Brain Dis. , vol.28 , Issue.4 , pp. 687-696
    • Möller, M.1    Du Preez, J.L.2    Viljoen, F.P.3    Berk, M.4    Harvey, B.H.5
  • 129
    • 14644414173 scopus 로고    scopus 로고
    • Mitochondrial DNA 3243A>G mutation and increased expression of LARS2 gene in the brains of patients with bipolar disorder and schizophrenia
    • Munakata K., Iwamoto K., Bundo M., Kato T. Mitochondrial DNA 3243A>G mutation and increased expression of LARS2 gene in the brains of patients with bipolar disorder and schizophrenia. Biol. Psychiatry 2005, 57(5):525-532.
    • (2005) Biol. Psychiatry , vol.57 , Issue.5 , pp. 525-532
    • Munakata, K.1    Iwamoto, K.2    Bundo, M.3    Kato, T.4
  • 130
    • 84856729192 scopus 로고    scopus 로고
    • Mitochondrial thiols in antioxidant protection and redox signaling: distinct roles for glutathionylation and other thiol modifications
    • 15
    • Murphy M.P. Mitochondrial thiols in antioxidant protection and redox signaling: distinct roles for glutathionylation and other thiol modifications. Antioxid. Redox Signaling 2012, 16(6):476-495. 15.
    • (2012) Antioxid. Redox Signaling , vol.16 , Issue.6 , pp. 476-495
    • Murphy, M.P.1
  • 131
    • 79952712223 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species drive proinflammatory cytokine production
    • Naik E., Dixit V.M. Mitochondrial reactive oxygen species drive proinflammatory cytokine production. J. Exp. Med. 2011, 208:417-420.
    • (2011) J. Exp. Med. , vol.208 , pp. 417-420
    • Naik, E.1    Dixit, V.M.2
  • 133
    • 0022333161 scopus 로고
    • A role for the mitochondrion in the protection of cells against calcium overload?
    • Nicholls D.G. A role for the mitochondrion in the protection of cells against calcium overload?. Prog. Brain Res. 1985, 63:97-106.
    • (1985) Prog. Brain Res. , vol.63 , pp. 97-106
    • Nicholls, D.G.1
  • 134
    • 0033971898 scopus 로고    scopus 로고
    • Mitochondria and neuronal survival
    • Nicholls D.G., Budd S.L. Mitochondria and neuronal survival. Physiol. Rev. 2000, 80:315-360.
    • (2000) Physiol. Rev. , vol.80 , pp. 315-360
    • Nicholls, D.G.1    Budd, S.L.2
  • 135
    • 68649104009 scopus 로고    scopus 로고
    • Mitochondrial calcium function and dysfunction in the central nervous system
    • Nicholls D.G. Mitochondrial calcium function and dysfunction in the central nervous system. Biochim. Biophys. Acta 2009, 1787:1416-1424.
    • (2009) Biochim. Biophys. Acta , vol.1787 , pp. 1416-1424
    • Nicholls, D.G.1
  • 136
    • 84906933568 scopus 로고    scopus 로고
    • Oxidative/Nitrosative Stress in Psychiatric Disorders: Are We There Yet?
    • O'Donnell P., Do K.Q., Arango C. Oxidative/Nitrosative Stress in Psychiatric Disorders: Are We There Yet?. Schizophr Bull 2014, 40(5):960-962.
    • (2014) Schizophr Bull , vol.40 , Issue.5 , pp. 960-962
    • O'Donnell, P.1    Do, K.Q.2    Arango, C.3
  • 137
    • 79958858244 scopus 로고    scopus 로고
    • Are there progressive brain changes in schizophrenia? A meta-analysis of structural magnetic resonance imaging studies
    • Olabi B., Ellison-Wright I., McIntosh A.M., Wood S.J., Bullmore E., Lawrie S.M. Are there progressive brain changes in schizophrenia? A meta-analysis of structural magnetic resonance imaging studies. Biol. Psychiatry 2011, 70(1):88-96.
    • (2011) Biol. Psychiatry , vol.70 , Issue.1 , pp. 88-96
    • Olabi, B.1    Ellison-Wright, I.2    McIntosh, A.M.3    Wood, S.J.4    Bullmore, E.5    Lawrie, S.M.6
  • 139
    • 78049249511 scopus 로고    scopus 로고
    • Disrupted-in-schizophrenia 1 (DISC1) plays essential roles in mitochondria in collaboration with Mitofilin
    • Park Y.U., Jeong J., Lee H., Mun J.Y., Kim J.H., Lee J.S., et al. Disrupted-in-schizophrenia 1 (DISC1) plays essential roles in mitochondria in collaboration with Mitofilin. Proc. Natl. Acad. Sci. U.S.A. 2010, 107(41):17785-17790.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , Issue.41 , pp. 17785-17790
    • Park, Y.U.1    Jeong, J.2    Lee, H.3    Mun, J.Y.4    Kim, J.H.5    Lee, J.S.6
  • 140
    • 84863446384 scopus 로고    scopus 로고
    • Molecular links between mitochondrial dysfunctions and schizophrenia
    • Park C., Park S.K. Molecular links between mitochondrial dysfunctions and schizophrenia. Mol. Cells 2012, 33(2):105-110.
    • (2012) Mol. Cells , vol.33 , Issue.2 , pp. 105-110
    • Park, C.1    Park, S.K.2
  • 143
    • 84891590984 scopus 로고    scopus 로고
    • Inhibition of mitochondrial complex III blocks neuronal differentiation and maintains embryonic stem cell pluripotency
    • Pereira S.L., Grãos M., Rodrigues A.S., Anjo S.I., Carvalho R.A., et al. Inhibition of mitochondrial complex III blocks neuronal differentiation and maintains embryonic stem cell pluripotency. PLoS One 2013, 8(12):e82095.
    • (2013) PLoS One , vol.8 , Issue.12 , pp. e82095
    • Pereira, S.L.1    Grãos, M.2    Rodrigues, A.S.3    Anjo, S.I.4    Carvalho, R.A.5
  • 145
    • 84891960724 scopus 로고    scopus 로고
    • Mitochondria impact brain function and cognition
    • Picard M., McEwen B.S. Mitochondria impact brain function and cognition. Proc. Natl. Acad. Sci. U.S.A. 2014, 111(1):7-8.
    • (2014) Proc. Natl. Acad. Sci. U.S.A. , vol.111 , Issue.1 , pp. 7-8
    • Picard, M.1    McEwen, B.S.2
  • 146
    • 77956319634 scopus 로고    scopus 로고
    • Calcium-dependent mitochondrial function and dysfunction in neurons
    • Pivovarova N.B., Andrews S.B. Calcium-dependent mitochondrial function and dysfunction in neurons. FEBS J. 2010, 277(18):3622-3636.
    • (2010) FEBS J. , vol.277 , Issue.18 , pp. 3622-3636
    • Pivovarova, N.B.1    Andrews, S.B.2
  • 147
    • 2942604863 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress
    • 643
    • Prabakaran S., Swatton J.E., Ryan M.M., Huffaker S.J., Huang J.T.-J., Griffin J.L., et al. Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress. Mol. Psychiatry 2004, 9(7):684-697. 643.
    • (2004) Mol. Psychiatry , vol.9 , Issue.7 , pp. 684-697
    • Prabakaran, S.1    Swatton, J.E.2    Ryan, M.M.3    Huffaker, S.J.4    Huang, J.T.-J.5    Griffin, J.L.6
  • 148
    • 0032775671 scopus 로고    scopus 로고
    • Mitochondrial function is differentially altered in the basal ganglia of chronic schizophrenics
    • Prince J.A., Blennow K., Gottfries C.G., Karlsson I., Oreland L. Mitochondrial function is differentially altered in the basal ganglia of chronic schizophrenics. Neuropsychopharmacology 1999, 21(3):372-379.
    • (1999) Neuropsychopharmacology , vol.21 , Issue.3 , pp. 372-379
    • Prince, J.A.1    Blennow, K.2    Gottfries, C.G.3    Karlsson, I.4    Oreland, L.5
  • 149
    • 74949127693 scopus 로고    scopus 로고
    • Progressive structural brain changes in schizophrenia
    • Puri B.K. Progressive structural brain changes in schizophrenia. Expert Rev. Neurotherap. 2010, 10(1):33-42.
    • (2010) Expert Rev. Neurotherap. , vol.10 , Issue.1 , pp. 33-42
    • Puri, B.K.1
  • 150
    • 0035469416 scopus 로고    scopus 로고
    • The mitochondrial antioxidant defence system and its response to oxidative stress?
    • Rabilloud T., Heller M., Rigobello M.P., Bindoli A., Aebersold R., Lunardi J. The mitochondrial antioxidant defence system and its response to oxidative stress?. Proteomics 2001, 1(9):1105-1110.
    • (2001) Proteomics , vol.1 , Issue.9 , pp. 1105-1110
    • Rabilloud, T.1    Heller, M.2    Rigobello, M.P.3    Bindoli, A.4    Aebersold, R.5    Lunardi, J.6
  • 151
  • 152
    • 60349098146 scopus 로고    scopus 로고
    • Elevated cerebrospinal fl{ligature}uid lactate concentrations in patients with bipolar disorder and schizophrenia: implications for the mitochondrial dysfunction hypothesis
    • 489e94
    • Regenold W.T., Phatak P., Marano C.M., Sassan A., Conley R.R., Kling M.A. Elevated cerebrospinal fl{ligature}uid lactate concentrations in patients with bipolar disorder and schizophrenia: implications for the mitochondrial dysfunction hypothesis. Biol. Psychiatr. 2009, 65:489e94.
    • (2009) Biol. Psychiatr. , vol.65
    • Regenold, W.T.1    Phatak, P.2    Marano, C.M.3    Sassan, A.4    Conley, R.R.5    Kling, M.A.6
  • 153
    • 81855161689 scopus 로고    scopus 로고
    • Mitochondrial detachment of hexokinase 1 in mood and psychotic disorders: implications for brain energy metabolism and neurotrophic signaling
    • Regenold W.T., Pratt M., Nekkalapu S., Shapiro P.S., Kristian T., Fiskum G. Mitochondrial detachment of hexokinase 1 in mood and psychotic disorders: implications for brain energy metabolism and neurotrophic signaling. J. Psychiatr. Res. 2012, 46(1):95-104.
    • (2012) J. Psychiatr. Res. , vol.46 , Issue.1 , pp. 95-104
    • Regenold, W.T.1    Pratt, M.2    Nekkalapu, S.3    Shapiro, P.S.4    Kristian, T.5    Fiskum, G.6
  • 154
    • 84884669370 scopus 로고    scopus 로고
    • Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients
    • Robicsek O., Karry R., Petit I., Salman-Kesner N., Müller F.-J., Klein E., et al. Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients. Mol. Psychiatry 2013, 18(10):1067-1076.
    • (2013) Mol. Psychiatry , vol.18 , Issue.10 , pp. 1067-1076
    • Robicsek, O.1    Karry, R.2    Petit, I.3    Salman-Kesner, N.4    Müller, F.-J.5    Klein, E.6
  • 155
    • 62849119061 scopus 로고    scopus 로고
    • Mitochondrial variants in schizophrenia, bipolar disorder, and major depressive disorder
    • Rollins B., Martin M.V., Sequeira P.A., Moon E.a., Morgan L.Z., Watson S.J., et al. Mitochondrial variants in schizophrenia, bipolar disorder, and major depressive disorder. PLoS One 2009, 4(3):e4913.
    • (2009) PLoS One , vol.4 , Issue.3 , pp. e4913
    • Rollins, B.1    Martin, M.V.2    Sequeira, P.A.3    Moon, E.4    Morgan, L.Z.5    Watson, S.J.6
  • 156
    • 79955476771 scopus 로고    scopus 로고
    • Perturbation in mitochondrial network dynamics and in complex I dependent cellular respiration in schizophrenia
    • Rosenfeld M., Brenner-Lavie H., Ari S.G.-B., Kavushansky A., Ben-Shachar D. Perturbation in mitochondrial network dynamics and in complex I dependent cellular respiration in schizophrenia. Biol. Psychiatry 2011, 69(10):980-988.
    • (2011) Biol. Psychiatry , vol.69 , Issue.10 , pp. 980-988
    • Rosenfeld, M.1    Brenner-Lavie, H.2    Ari, S.G.-B.3    Kavushansky, A.4    Ben-Shachar, D.5
  • 157
    • 0037314215 scopus 로고    scopus 로고
    • Neuronal degeneration and mitochondrial dysfunction?
    • Schon E.A., Manfredi G. Neuronal degeneration and mitochondrial dysfunction?. J Clin Invest. 2003, 111(3):303-312.
    • (2003) J Clin Invest. , vol.111 , Issue.3 , pp. 303-312
    • Schon, E.A.1    Manfredi, G.2
  • 159
    • 84867522393 scopus 로고    scopus 로고
    • Heteroplasmy of mouse mtDNA is genetically unstable and results in altered behavior and cognition
    • Sharpley M.S., et al. Heteroplasmy of mouse mtDNA is genetically unstable and results in altered behavior and cognition. Cell 2012, 151(2):333-343.
    • (2012) Cell , vol.151 , Issue.2 , pp. 333-343
    • Sharpley, M.S.1
  • 161
    • 60049083615 scopus 로고    scopus 로고
    • A comparative study of oxidative stress and interrelationship of important antioxidants in haloperidol and olanzapine treated patients suffering from schizophrenia
    • Singh O.P., Chakraborty I., Datta S. A comparative study of oxidative stress and interrelationship of important antioxidants in haloperidol and olanzapine treated patients suffering from schizophrenia. Indian J. Psychiatry 2008, 50(3):1-8.
    • (2008) Indian J. Psychiatry , vol.50 , Issue.3 , pp. 1-8
    • Singh, O.P.1    Chakraborty, I.2    Datta, S.3
  • 164
    • 3342910554 scopus 로고    scopus 로고
    • Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury
    • Starkov A.A., Chinopoulos C., Fiskum G. Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury. Cell Calcium 2004, 36:257-264.
    • (2004) Cell Calcium , vol.36 , pp. 257-264
    • Starkov, A.A.1    Chinopoulos, C.2    Fiskum, G.3
  • 165
    • 13844281067 scopus 로고    scopus 로고
    • The powerhouse takes control of the call: is the mitochondrial permeability transition a viable therapeutic target against neuronal dysfunction and death?
    • Stavrovskaya I.G., Kristal B.S. The powerhouse takes control of the call: is the mitochondrial permeability transition a viable therapeutic target against neuronal dysfunction and death?. Free Radical Biol. Med. 2005, 38(6):687-697.
    • (2005) Free Radical Biol. Med. , vol.38 , Issue.6 , pp. 687-697
    • Stavrovskaya, I.G.1    Kristal, B.S.2
  • 166
    • 27144492384 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in bipolar disorder: evidence from magnetic resonance spectroscopy research
    • Stork C., Renshaw P.F. Mitochondrial dysfunction in bipolar disorder: evidence from magnetic resonance spectroscopy research. Mol. Psychiatry 2005, 10:900-919.
    • (2005) Mol. Psychiatry , vol.10 , pp. 900-919
    • Stork, C.1    Renshaw, P.F.2
  • 167
    • 22144432283 scopus 로고    scopus 로고
    • A systematic review of the prevalence of schizophrenia
    • Saha S., Chant D., Welham J., McGrath J. A systematic review of the prevalence of schizophrenia. PLoS Med. 2005, 2(5):e141.
    • (2005) PLoS Med. , vol.2 , Issue.5 , pp. e141
    • Saha, S.1    Chant, D.2    Welham, J.3    McGrath, J.4
  • 168
    • 0030891028 scopus 로고    scopus 로고
    • Mitochondrial involvement in post-tetanic potentiation of synaptic transmission
    • Tang Y., Zucker R.S. Mitochondrial involvement in post-tetanic potentiation of synaptic transmission. Neuron 1997, 18:483-491.
    • (1997) Neuron , vol.18 , pp. 483-491
    • Tang, Y.1    Zucker, R.S.2
  • 169
    • 84885474048 scopus 로고    scopus 로고
    • Changes in oxidative stress markers in patients with schizophrenia: the effect of antipsychotic drugs
    • Tsai M.C., Liou C.W., Lin T.K., Lin I.M., Huang T.L. Changes in oxidative stress markers in patients with schizophrenia: the effect of antipsychotic drugs. Psychiatry Res. 2013, 209(3):284-290.
    • (2013) Psychiatry Res. , vol.209 , Issue.3 , pp. 284-290
    • Tsai, M.C.1    Liou, C.W.2    Lin, T.K.3    Lin, I.M.4    Huang, T.L.5
  • 170
    • 70449094829 scopus 로고    scopus 로고
    • Analysis of mitochondrial DNA vriants in Japanese patients with schizophrenia
    • Ueno H., Nishigaki Y., Kong Q.P., Fuku N., Kojima S., Iwata N., et al. Analysis of mitochondrial DNA vriants in Japanese patients with schizophrenia. Mitochondrion 2009, 9:385-393.
    • (2009) Mitochondrion , vol.9 , pp. 385-393
    • Ueno, H.1    Nishigaki, Y.2    Kong, Q.P.3    Fuku, N.4    Kojima, S.5    Iwata, N.6
  • 173
    • 68949180394 scopus 로고    scopus 로고
    • Schizophrenia
    • Van Os J., Kapur S. Schizophrenia. Lancet 2009, 374(9690):635-645.
    • (2009) Lancet , vol.374 , Issue.9690 , pp. 635-645
    • Van Os, J.1    Kapur, S.2
  • 175
    • 84873474114 scopus 로고    scopus 로고
    • Pleiotropic actions of estrogen: a mitochondrial matter
    • Velarde M.C. Pleiotropic actions of estrogen: a mitochondrial matter. Physiol. Genomics 2013, 45(3):106-109.
    • (2013) Physiol. Genomics , vol.45 , Issue.3 , pp. 106-109
    • Velarde, M.C.1
  • 176
    • 84877325936 scopus 로고    scopus 로고
    • The TRIPS (Toll-like receptors in immuno-inflammatory pathogenesis) hypothesis: a novel postulate to understand schizophrenia
    • Venkatasubramanian G., Debnath M. The TRIPS (Toll-like receptors in immuno-inflammatory pathogenesis) hypothesis: a novel postulate to understand schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiat. 2013, 44:301-311.
    • (2013) Prog. Neuropsychopharmacol. Biol. Psychiat. , vol.44 , pp. 301-311
    • Venkatasubramanian, G.1    Debnath, M.2
  • 178
    • 84861809553 scopus 로고    scopus 로고
    • New evidence for the involvement of mitochondrial inheritance in schizophrenia: results from a cross-sectional study evaluating the risk of illness in relatives of schizophrenia patients?
    • Verge B., Alonso Y., Miralles C., Valero J., Vilella E., Boles R.G., Martorell L. New evidence for the involvement of mitochondrial inheritance in schizophrenia: results from a cross-sectional study evaluating the risk of illness in relatives of schizophrenia patients?. J. Clin. Psychiatry 2012, 73(5):684-690.
    • (2012) J. Clin. Psychiatry , vol.73 , Issue.5 , pp. 684-690
    • Verge, B.1    Alonso, Y.2    Miralles, C.3    Valero, J.4    Vilella, E.5    Boles, R.G.6    Martorell, L.7
  • 179
    • 84870855298 scopus 로고    scopus 로고
    • Progressive loss of cortical gray matter in schizophrenia: a meta-analysis and meta-regression of longitudinal MRI studies
    • Vita A., De Peri L., Deste G., Sacchetti E. Progressive loss of cortical gray matter in schizophrenia: a meta-analysis and meta-regression of longitudinal MRI studies. Transl. Psychiatry 2012, 2(11):e190.
    • (2012) Transl. Psychiatry , vol.2 , Issue.11 , pp. e190
    • Vita, A.1    De Peri, L.2    Deste, G.3    Sacchetti, E.4
  • 180
    • 77956813407 scopus 로고    scopus 로고
    • Mitochondrial protection attenuates inflammation-induced impairment of neurogenesis in vitro and in vivo
    • Voloboueva L.A., Lee S.W., Emery J.F., Palmer T.D., Giffard R.G. Mitochondrial protection attenuates inflammation-induced impairment of neurogenesis in vitro and in vivo. J. Neurosci. 2010, 30(37):12242-12251.
    • (2010) J. Neurosci. , vol.30 , Issue.37 , pp. 12242-12251
    • Voloboueva, L.A.1    Lee, S.W.2    Emery, J.F.3    Palmer, T.D.4    Giffard, R.G.5
  • 182
    • 36849076332 scopus 로고    scopus 로고
    • Progressive brain volume loss in schizophrenia over the course of the illness: evidence of maturational abnormalities in early adulthood
    • Van Haren N.E.M., Hulshoff Pol H.E., Schnack H.G., et al. Progressive brain volume loss in schizophrenia over the course of the illness: evidence of maturational abnormalities in early adulthood. Biol. Psychiatry 2008, 63:106-113.
    • (2008) Biol. Psychiatry , vol.63 , pp. 106-113
    • Van Haren, N.E.M.1    Hulshoff Pol, H.E.2    Schnack, H.G.3
  • 183
    • 0025673972 scopus 로고
    • Delayed decreases in specific brain mitochondrial electron transfer complex activities and cytochrome concentrations following anoxia/ischemia?
    • Wagner K.R., Kleinholz M., Myers R.E. Delayed decreases in specific brain mitochondrial electron transfer complex activities and cytochrome concentrations following anoxia/ischemia?. J. Neurol. Sci. 1990, 100(1-2):142-151.
    • (1990) J. Neurol. Sci. , vol.100 , Issue.1-2 , pp. 142-151
    • Wagner, K.R.1    Kleinholz, M.2    Myers, R.E.3
  • 184
    • 84885480919 scopus 로고    scopus 로고
    • Mitochondrial haplogroups and hypervariable region polymorphisms in schizophrenia: a case-control study
    • Wang G., Zhang Y., Zhang Y., Dong Y., Lv Z., Sun M., et al. Mitochondrial haplogroups and hypervariable region polymorphisms in schizophrenia: a case-control study. Psychiatry Res. 2013, 209(3):279-283.
    • (2013) Psychiatry Res. , vol.209 , Issue.3 , pp. 279-283
    • Wang, G.1    Zhang, Y.2    Zhang, Y.3    Dong, Y.4    Lv, Z.5    Sun, M.6
  • 185
    • 61349091797 scopus 로고    scopus 로고
    • Oxidative stress in developmental origins of disease: teratogenesis, neurodevelopmental deficits, and cancer
    • Wells P.G., McCallum G.P., Chen C.S., Henderson J.T., Lee C.J.J., Perstin J., et al. Oxidative stress in developmental origins of disease: teratogenesis, neurodevelopmental deficits, and cancer. Toxicol. Sci. 2009, 108(1):4-18.
    • (2009) Toxicol. Sci. , vol.108 , Issue.1 , pp. 4-18
    • Wells, P.G.1    McCallum, G.P.2    Chen, C.S.3    Henderson, J.T.4    Lee, C.J.J.5    Perstin, J.6
  • 186
    • 0038714272 scopus 로고    scopus 로고
    • Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function
    • J.E. Wilson, 2003, Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function, The Journal of Experimental Biology, 206, 2049-2057.
    • (2003) The Journal of Experimental Biology , vol.206 , pp. 2049-2057
    • Wilson, J.E.1
  • 187
    • 84872686195 scopus 로고    scopus 로고
    • Cell signaling and mitochondrial dynamics: implications for neuronal function and neurodegenerative disease
    • Wilson T.J., Slupe A.M., Strack S. Cell signaling and mitochondrial dynamics: implications for neuronal function and neurodegenerative disease. Neurobiol. Dis. 2013, 51:13-26.
    • (2013) Neurobiol. Dis. , vol.51 , pp. 13-26
    • Wilson, T.J.1    Slupe, A.M.2    Strack, S.3
  • 188
    • 67049154214 scopus 로고    scopus 로고
    • Neurobiology of schizophrenia spectrum disorders: the role of oxidative stress?
    • Wood S.J., Yücel M., Pantelis C., Berk M. Neurobiology of schizophrenia spectrum disorders: the role of oxidative stress?. Ann. Acad. Med. Singapore 2009, 38(5):396-406.
    • (2009) Ann. Acad. Med. Singapore , vol.38 , Issue.5 , pp. 396-406
    • Wood, S.J.1    Yücel, M.2    Pantelis, C.3    Berk, M.4
  • 189
    • 84864311250 scopus 로고    scopus 로고
    • Estrogen regulation of mitochondrial bioenergetics: implications for prevention of Alzheimer's disease
    • Yao J., Brinton R.D. Estrogen regulation of mitochondrial bioenergetics: implications for prevention of Alzheimer's disease. Adv. Pharmacol. 2012, 64:327-371.
    • (2012) Adv. Pharmacol. , vol.64 , pp. 327-371
    • Yao, J.1    Brinton, R.D.2
  • 190
    • 79951576719 scopus 로고    scopus 로고
    • Calcium-related signaling pathways contributed to dopamine-induced cortical neuron apoptosis
    • Zhang L., Yang H., Zhao H., Zhao C. Calcium-related signaling pathways contributed to dopamine-induced cortical neuron apoptosis. Neurochem. Int. 2011, 58:281-294.
    • (2011) Neurochem. Int. , vol.58 , pp. 281-294
    • Zhang, L.1    Yang, H.2    Zhao, H.3    Zhao, C.4
  • 192
    • 38149092393 scopus 로고    scopus 로고
    • Impaired hippocampal neurogenesis is involved in cognitive dysfunction induced by thiamine deficiency at early pre-pathological lesion stage
    • Zhao N., Zhong C., Wang Y., Zhao Y., Gong N., Zhou G., Xu T., Hong Z. Impaired hippocampal neurogenesis is involved in cognitive dysfunction induced by thiamine deficiency at early pre-pathological lesion stage. Neurobiol. Dis. 2008, 29:176-185.
    • (2008) Neurobiol. Dis. , vol.29 , pp. 176-185
    • Zhao, N.1    Zhong, C.2    Wang, Y.3    Zhao, Y.4    Gong, N.5    Zhou, G.6    Xu, T.7    Hong, Z.8
  • 193
    • 0024600340 scopus 로고
    • Short-term synaptic plasticity
    • Zucker R.S. Short-term synaptic plasticity. Annu. Rev. Neurosci. 1989, 12:13-31.
    • (1989) Annu. Rev. Neurosci. , vol.12 , pp. 13-31
    • Zucker, R.S.1


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