The powerhouse takes control of the cell: Is the mitochondrial permeability transition a viable therapeutic target against neuronal dysfunction and death?

Free Radical Biology and Medicine

Volumn 38, Issue 6, 2005, Pages 687-697

  Stavrovskaya, Irina G ^a   Kristal, Bruce S ^a,b  

^a BURKE MEDICAL RESEARCH INSTITUTE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Alzheimer's disease; Apoptosis; Huntington's disease; Mitochondria; Parkinson's disease; Permeability transition; Stroke

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; ALDEHYDE; ANTIOXIDANT; CLOMIPRAMINE; CREATINE; CYCLOSPORIN; DITHIOTHREITOL; FLUPHENAZINE; HETEROCYCLIC COMPOUND; HYDROXYTYROSOL; MAGNESIUM; METITEPINE; MINOCYCLINE; N ETHYLMALEIMIDE; NEUROPROTECTIVE AGENT; NEUROTOXIN; NITRIC OXIDE SYNTHASE INHIBITOR; PHENOTHIAZINE DERIVATIVE; PHOSPHOLIPASE A2 INHIBITOR; PROMETHAZINE; TACROLIMUS; TAUROURSODEOXYCHOLIC ACID;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; APOPTOSIS; BRAIN MITOCHONDRION; CALCIUM TRANSPORT; CAROTID ENDARTERECTOMY; CELL DEATH; CELL ISOLATION; CELL LOSS; CENTRAL NERVOUS SYSTEM DISEASE; DEGENERATIVE DISEASE; DRUG EFFICACY; DRUG SENSITIVITY; ENZYME ACTIVITY; HIGH RISK PATIENT; HUMAN; HUNTINGTON CHOREA; LIPID MEMBRANE; LIPID PEROXIDATION; LIVER MITOCHONDRION; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SODIUM CALCIUM EXCHANGE; STROKE; TRANSGENE;

JANUS;

EID: 13844281067     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.11.032     Document Type: Review

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