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Volumn 10, Issue 1, 2010, Pages 33-42

Progressive structural brain changes in schizophrenia

Author keywords

Atypical antipsychotic medication; Brain changes; Magnetic resonance imaging; Schizophrenia; Typical antipsychotic medication

Indexed keywords

HALOPERIDOL; OLANZAPINE; RISPERIDONE; ZIPRASIDONE;

EID: 74949127693     PISSN: 14737175     EISSN: 17448360     Source Type: Journal    
DOI: 10.1586/ern.09.142     Document Type: Review
Times cited : (39)

References (49)
  • 1
    • 74949111206 scopus 로고    scopus 로고
    • Puri BK. Serial neuroimaging in schizophrenia using image segmentation, subvoxel registration, and quantitation (PhD thesis). Faculty of Medicine. Imperial College London, London, UK (2001).
    • Puri BK. Serial neuroimaging in schizophrenia using image segmentation, subvoxel registration, and quantitation (PhD thesis). Faculty of Medicine. Imperial College London, London, UK (2001).
  • 2
    • 84921009118 scopus 로고    scopus 로고
    • Johnstone EC, Crow TJ, Frith CD, Husband J, Kreel L. Cerebral ventricular size and cognitive impairment in chronic schizophrenia. Lancet 2(7992), 924-926 (1976). •• A landmark study. The first major systematic application of CT to schizophrenia research.
    • Johnstone EC, Crow TJ, Frith CD, Husband J, Kreel L. Cerebral ventricular size and cognitive impairment in chronic schizophrenia. Lancet 2(7992), 924-926 (1976). •• A landmark study. The first major systematic application of CT to schizophrenia research.
  • 3
    • 0015911128 scopus 로고
    • Computerized transverse axial scanning (tomography). 1. Description of system
    • Hounsfield GN. Computerized transverse axial scanning (tomography). 1. Description of system. Br. J. Radiol. 46(552), 1016-1022 (1973).
    • (1973) Br. J. Radiol , vol.46 , Issue.552 , pp. 1016-1022
    • Hounsfield, G.N.1
  • 4
    • 0025203531 scopus 로고    scopus 로고
    • Abou-Saleh MT. Editorial preface. In: Brain Imaging in Psychiatry. Br. J. Psychiatry 157(Suppl. 9), 7-9 (1990).
    • Abou-Saleh MT. Editorial preface. In: Brain Imaging in Psychiatry. Br. J. Psychiatry 157(Suppl. 9), 7-9 (1990).
  • 5
    • 0019984264 scopus 로고    scopus 로고
    • Bydder GM, Steiner RE. NMR imaging of the brain. Neuroradiology 23(5), 231-240 (1982). •• A landmark study in the field of structural neuroimaging using MRI.
    • Bydder GM, Steiner RE. NMR imaging of the brain. Neuroradiology 23(5), 231-240 (1982). •• A landmark study in the field of structural neuroimaging using MRI.
  • 6
  • 7
    • 0023947312 scopus 로고
    • Quantitative neuroanatomy in schizophrenia. A controlled magnetic resonance imaging study
    • Kelsoe JR Jr, Cadet JL, Pickar D, Weinberger DR. Quantitative neuroanatomy in schizophrenia. A controlled magnetic resonance imaging study. Arch. Gen. Psychiatry 45(6), 533-541 (1988).
    • (1988) Arch. Gen. Psychiatry , vol.45 , Issue.6 , pp. 533-541
    • Kelsoe Jr, J.R.1    Cadet, J.L.2    Pickar, D.3    Weinberger, D.R.4
  • 8
    • 0028998370 scopus 로고
    • Schizophrenia - a brain disease? A critical review of structural and functional cerebral abnormality in the disorder
    • An excellent review. Contains an excellent account of neuroimaging studies of schizophrenia up to the mid-1990s, ••
    • Chua SE, McKenna PJ. Schizophrenia - a brain disease? A critical review of structural and functional cerebral abnormality in the disorder. Br. J. Psychiatry 166(5), 563-582 (1995). •• An excellent review. Contains an excellent account of neuroimaging studies of schizophrenia up to the mid-1990s.
    • (1995) Br. J. Psychiatry , vol.166 , Issue.5 , pp. 563-582
    • Chua, S.E.1    McKenna, P.J.2
  • 9
    • 0023215296 scopus 로고
    • Implications of normal brain development for the pathogenesis of schizophrenia
    • A landmark paper which has been an important driver for many subsequent neuroimaging studies in this field, ••
    • Weinberger DR. Implications of normal brain development for the pathogenesis of schizophrenia. Arch. Gen. Psychiatry 44(7), 660-669 (1987). •• A landmark paper which has been an important driver for many subsequent neuroimaging studies in this field.
    • (1987) Arch. Gen. Psychiatry , vol.44 , Issue.7 , pp. 660-669
    • Weinberger, D.R.1
  • 10
    • 0022471085 scopus 로고    scopus 로고
    • Roberts GW, Colter N, Lofthouse R, Bogerts B, Zech M, Crow TJ. Gliosis in schizophrenia: a survey. Biol. Psychiatry 21(11), 1043-1050 (1986).
    • Roberts GW, Colter N, Lofthouse R, Bogerts B, Zech M, Crow TJ. Gliosis in schizophrenia: a survey. Biol. Psychiatry 21(11), 1043-1050 (1986).
  • 11
    • 0029589363 scopus 로고
    • The Mackenzie Davidson Memorial lecture: Detection of small changes to the brain with serial magnetic resonance imaging
    • Bydder GM. The Mackenzie Davidson Memorial lecture: detection of small changes to the brain with serial magnetic resonance imaging. Br. J. Radiol. 68(816), 1271-1295 (1995).
    • (1995) Br. J. Radiol , vol.68 , Issue.816 , pp. 1271-1295
    • Bydder, G.M.1
  • 12
    • 0033933649 scopus 로고    scopus 로고
    • Voxel-based morphometry - the methods
    • Ashburner J, Friston KJ. Voxel-based morphometry - the methods. Neuroimage 11(6 Pt 1), 805-821 (2000).
    • (2000) Neuroimage , vol.11 , Issue.6 PART 1 , pp. 805-821
    • Ashburner, J.1    Friston, K.J.2
  • 13
    • 0033056267 scopus 로고    scopus 로고
    • Correlation between structural and functional changes in brain in an idiopathic headache syndrome
    • May A, Ashburner J, Buchel C et al. Correlation between structural and functional changes in brain in an idiopathic headache syndrome. Nat. Med. 5(7), 836-838 (1999).
    • (1999) Nat. Med , vol.5 , Issue.7 , pp. 836-838
    • May, A.1    Ashburner, J.2    Buchel, C.3
  • 14
    • 56249127096 scopus 로고    scopus 로고
    • Reductions in frontal, temporal and parietal volume associated with the onset of psychosis
    • Borgwardt SJ, McGuire PK, Aston J et al. Reductions in frontal, temporal and parietal volume associated with the onset of psychosis. Schizophr. Res. 106(2-3), 108-114 (2008).
    • (2008) Schizophr. Res , vol.106 , Issue.2-3 , pp. 108-114
    • Borgwardt, S.J.1    McGuire, P.K.2    Aston, J.3
  • 15
    • 0034735925 scopus 로고    scopus 로고
    • Johnstone EC, Abukmeil SS, Byrne M et al. Edinburgh High Risk Study - findings after four years: demographic, attainment and psychopathological issues. Schizophr. Res. 46(1), 1-15 (2000). •• Key study from the Edinburgh High Risk group, who are the first prospectively to examine changes in brain structure of genetically high-risk subjects.
    • Johnstone EC, Abukmeil SS, Byrne M et al. Edinburgh High Risk Study - findings after four years: demographic, attainment and psychopathological issues. Schizophr. Res. 46(1), 1-15 (2000). •• Key study from the Edinburgh High Risk group, who are the first prospectively to examine changes in brain structure of genetically high-risk subjects.
  • 17
    • 17844362223 scopus 로고    scopus 로고
    • Grey matter changes over time in high risk subjects developing schizophrenia
    • Job DE, Whalley HC, Johnstone EC, Lawrie SM. Grey matter changes over time in high risk subjects developing schizophrenia. Neuroimage 25(4), 1023-1030 (2005).
    • (2005) Neuroimage , vol.25 , Issue.4 , pp. 1023-1030
    • Job, D.E.1    Whalley, H.C.2    Johnstone, E.C.3    Lawrie, S.M.4
  • 19
    • 67650457029 scopus 로고    scopus 로고
    • Use of neuroanatomical pattern classification to identify subjects in at-risk mental states of psychosis and predict disease transition
    • A landmark study, ••
    • Koutsouleris N, Meisenzahl EM, Davatzikos C et al. Use of neuroanatomical pattern classification to identify subjects in at-risk mental states of psychosis and predict disease transition. Arch. Gen. Psychiatry 66(7), 700-712 (2009). •• A landmark study.
    • (2009) Arch. Gen. Psychiatry , vol.66 , Issue.7 , pp. 700-712
    • Koutsouleris, N.1    Meisenzahl, E.M.2    Davatzikos, C.3
  • 20
    • 46249107347 scopus 로고    scopus 로고
    • Structural brain alterations in subjects at high-risk of psychosis: A voxel-based morphometric study
    • Meisenzahl EM, Koutsouleris N, Gaser C et al. Structural brain alterations in subjects at high-risk of psychosis: a voxel-based morphometric study. Schizophr. Res. 102(1-3), 150-162 (2008).
    • (2008) Schizophr. Res , vol.102 , Issue.1-3 , pp. 150-162
    • Meisenzahl, E.M.1    Koutsouleris, N.2    Gaser, C.3
  • 21
    • 36148988271 scopus 로고    scopus 로고
    • Structural brain abnormalities in individuals with an at-risk mental state who later develop psychosis
    • Borgwardt SJ, McGuire PK, Aston J et al. Structural brain abnormalities in individuals with an at-risk mental state who later develop psychosis. Br. J. Psychiatry Suppl. 51, S69-S75 (2007).
    • (2007) Br. J. Psychiatry Suppl , vol.51
    • Borgwardt, S.J.1    McGuire, P.K.2    Aston, J.3
  • 22
    • 1242292413 scopus 로고    scopus 로고
    • DeLisi LE, Sakuma M, Maurizio AM, Relja M, Hoff AL. Cerebral ventricular change over the first 10 years after the onset of schizophrenia. Psychiatry Res. 130(1), 57-70 (2004). •• A landmark study.
    • DeLisi LE, Sakuma M, Maurizio AM, Relja M, Hoff AL. Cerebral ventricular change over the first 10 years after the onset of schizophrenia. Psychiatry Res. 130(1), 57-70 (2004). •• A landmark study.
  • 23
    • 38849159238 scopus 로고    scopus 로고
    • Investigating the neuropsychological and neuroanatomical changes that occur over the first 2-3 years of illness in patients with first-episode schizophrenia
    • Zipparo L, Whitford TJ, Redoblado Hodge MA et al. Investigating the neuropsychological and neuroanatomical changes that occur over the first 2-3 years of illness in patients with first-episode schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry 32(2), 531-538 (2008).
    • (2008) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.32 , Issue.2 , pp. 531-538
    • Zipparo, L.1    Whitford, T.J.2    Redoblado Hodge, M.A.3
  • 24
    • 40049102475 scopus 로고    scopus 로고
    • What happens after the first episode? A review of progressive brain changes in chronically ill patients with schizophrenia
    • An important review, ••
    • Hulshoff Pol HE, Kahn RS. What happens after the first episode? A review of progressive brain changes in chronically ill patients with schizophrenia. Schizophr. Bull. 34(2), 354-366 (2008). •• An important review.
    • (2008) Schizophr. Bull , vol.34 , Issue.2 , pp. 354-366
    • Hulshoff Pol, H.E.1    Kahn, R.S.2
  • 25
    • 57749182668 scopus 로고    scopus 로고
    • Psychosis and brain volume changes during the first five years of schizophrenia
    • Cahn W, Rais M, Stigter FP et al. Psychosis and brain volume changes during the first five years of schizophrenia. Eur. Neuropsychopharmacol. 19(2), 147-151 (2009).
    • (2009) Eur. Neuropsychopharmacol , vol.19 , Issue.2 , pp. 147-151
    • Cahn, W.1    Rais, M.2    Stigter, F.P.3
  • 26
    • 69849088544 scopus 로고    scopus 로고
    • Progressive gray matter changes in first episode schizophrenia: A 4-year longitudinal magnetic resonance study using VBM
    • Mane A, Falcon C, Mateos JJ et al. Progressive gray matter changes in first episode schizophrenia: A 4-year longitudinal magnetic resonance study using VBM. Schizophr. Res. 114(1-3), 136-143 (2009).
    • (2009) Schizophr. Res , vol.114 , Issue.1-3 , pp. 136-143
    • Mane, A.1    Falcon, C.2    Mateos, J.J.3
  • 27
    • 68049125120 scopus 로고    scopus 로고
    • Longitudinal assessment of gray and white matter in chronic schizophrenia: A combined diffusion-tensor and structural magnetic resonance imaging study
    • Mitelman SA, Canfield EL, Newmark RE et al. Longitudinal assessment of gray and white matter in chronic schizophrenia: a combined diffusion-tensor and structural magnetic resonance imaging study. Open Neuroimag. J. 3, 31-47 (2009).
    • (2009) Open Neuroimag. J , vol.3 , pp. 31-47
    • Mitelman, S.A.1    Canfield, E.L.2    Newmark, R.E.3
  • 28
    • 57749176207 scopus 로고    scopus 로고
    • Progression of brain volume changes in adolescent-onset psychosis
    • Reig S, Moreno C, Moreno D et al. Progression of brain volume changes in adolescent-onset psychosis. Schizophr. Bull. 35(1), 233-243 (2009).
    • (2009) Schizophr. Bull , vol.35 , Issue.1 , pp. 233-243
    • Reig, S.1    Moreno, C.2    Moreno, D.3
  • 29
    • 28444491442 scopus 로고    scopus 로고
    • Regional deficits in brain volume in schizophrenia: A meta-analysis of voxel-based morphometry studies
    • Honea R, Crow TJ, Passingham D, Mackay CE. Regional deficits in brain volume in schizophrenia: a meta-analysis of voxel-based morphometry studies. Am. J. Psychiatry 162(12), 2233-2245 (2005).
    • (2005) Am. J. Psychiatry , vol.162 , Issue.12 , pp. 2233-2245
    • Honea, R.1    Crow, T.J.2    Passingham, D.3    Mackay, C.E.4
  • 30
    • 67650032529 scopus 로고    scopus 로고
    • A prospective longitudinal volumetric MRI study of superior temporal gyrus gray matter and amygdala - hippocampal complex in chronic schizophrenia
    • Yoshida T, McCarley RW, Nakamura M et al. A prospective longitudinal volumetric MRI study of superior temporal gyrus gray matter and amygdala - hippocampal complex in chronic schizophrenia. Schizophr. Res. 113(1), 84-94 (2009).
    • (2009) Schizophr. Res , vol.113 , Issue.1 , pp. 84-94
    • Yoshida, T.1    McCarley, R.W.2    Nakamura, M.3
  • 31
    • 0037228202 scopus 로고    scopus 로고
    • Progressive decrease of left superior temporal gyrus gray matter volume in patients with first-episode schizophrenia
    • Kasai K, Shenton ME, Salisbury DF et al. Progressive decrease of left superior temporal gyrus gray matter volume in patients with first-episode schizophrenia. Am. J. Psychiatry 160(1), 156-164 (2003).
    • (2003) Am. J. Psychiatry , vol.160 , Issue.1 , pp. 156-164
    • Kasai, K.1    Shenton, M.E.2    Salisbury, D.F.3
  • 32
    • 64849086184 scopus 로고    scopus 로고
    • Progressive gray matter reduction of the superior temporal gyrus during transition to psychosis
    • Takahashi T, Wood SJ, Yung AR et al. Progressive gray matter reduction of the superior temporal gyrus during transition to psychosis. Arch. Gen. Psychiatry 66(4), 366-376 (2009).
    • (2009) Arch. Gen. Psychiatry , vol.66 , Issue.4 , pp. 366-376
    • Takahashi, T.1    Wood, S.J.2    Yung, A.R.3
  • 33
    • 60349123423 scopus 로고    scopus 로고
    • Follow-up MRI study of the insular cortex in first-episode psychosis and chronic schizophrenia
    • Takahashi T, Wood SJ, Soulsby B et al. Follow-up MRI study of the insular cortex in first-episode psychosis and chronic schizophrenia. Schizophr. Res. 108(1-3), 49-56 (2009).
    • (2009) Schizophr. Res , vol.108 , Issue.1-3 , pp. 49-56
    • Takahashi, T.1    Wood, S.J.2    Soulsby, B.3
  • 34
    • 67349241355 scopus 로고    scopus 로고
    • Insular cortex gray matter changes in individuals at ultra-high risk of developing psychosis
    • Takahashi T, Wood SJ, Yung AR et al. Insular cortex gray matter changes in individuals at ultra-high risk of developing psychosis. Schizophr. Res. 111(1-3), 94-102 (2009).
    • (2009) Schizophr. Res , vol.111 , Issue.1-3 , pp. 94-102
    • Takahashi, T.1    Wood, S.J.2    Yung, A.R.3
  • 35
    • 70349669596 scopus 로고    scopus 로고
    • Brain surface contraction mapped in first-episode schizophrenia: A longitudinal magnetic resonance imaging study
    • Sun D, Stuart GW, Jenkinson M et al. Brain surface contraction mapped in first-episode schizophrenia: a longitudinal magnetic resonance imaging study. Mol. Psychiatry 14(10), 976-986 (2008).
    • (2008) Mol. Psychiatry , vol.14 , Issue.10 , pp. 976-986
    • Sun, D.1    Stuart, G.W.2    Jenkinson, M.3
  • 36
    • 68049120178 scopus 로고    scopus 로고
    • Poor outcome in chronic schizophrenia is associated with progressive loss of volume of the putamen
    • Mitelman SA, Canfield EL, Chu KW et al. Poor outcome in chronic schizophrenia is associated with progressive loss of volume of the putamen. Schizophr. Res. 113(2-3), 241-245 (2009).
    • (2009) Schizophr. Res , vol.113 , Issue.2-3 , pp. 241-245
    • Mitelman, S.A.1    Canfield, E.L.2    Chu, K.W.3
  • 37
    • 69849090943 scopus 로고    scopus 로고
    • A longitudinal study of the corpus callosum in chronic schizophrenia
    • Mitelman SA, Nikiforova YK, Canfield EL et al. A longitudinal study of the corpus callosum in chronic schizophrenia. Schizophr. Res. 114(1-3), 144-153 (2009).
    • (2009) Schizophr. Res , vol.114 , Issue.1-3 , pp. 144-153
    • Mitelman, S.A.1    Nikiforova, Y.K.2    Canfield, E.L.3
  • 38
    • 67349127240 scopus 로고    scopus 로고
    • Borgwardt SJ, Dickey C, Hulshoff Pol H, Whitford TJ, DeLisi LE. Workshop on defining the significance of progressive brain change in schizophrenia: December 12, 2008 American College of Neuropsychopharmacology (ACNP) all-day satellite, Scottsdale, Arizona. The rapporteurs' report. Schizophr. Res. 112(1-3), 32-45 (2009).
    • Borgwardt SJ, Dickey C, Hulshoff Pol H, Whitford TJ, DeLisi LE. Workshop on defining the significance of progressive brain change in schizophrenia: December 12, 2008 American College of Neuropsychopharmacology (ACNP) all-day satellite, Scottsdale, Arizona. The rapporteurs' report. Schizophr. Res. 112(1-3), 32-45 (2009).
  • 39
    • 24344436398 scopus 로고    scopus 로고
    • Structural brain imaging evidence for multiple pathological processes at different stages of brain development in schizophrenia
    • An important theoretical paper, ••
    • Pantelis C, Yucel M, Wood SJ et al. Structural brain imaging evidence for multiple pathological processes at different stages of brain development in schizophrenia. Schizophr. Bull. 31(3), 672-696 (2005). •• An important theoretical paper.
    • (2005) Schizophr. Bull , vol.31 , Issue.3 , pp. 672-696
    • Pantelis, C.1    Yucel, M.2    Wood, S.J.3
  • 40
    • 60249087534 scopus 로고    scopus 로고
    • Progressive brain structural changes mapped as psychosis develops in 'at-risk' individuals
    • Sun D, Phillips L, Velakoulis D et al. Progressive brain structural changes mapped as psychosis develops in 'at-risk' individuals. Schizophr. Res. 108(1-3), 85-92 (2009).
    • (2009) Schizophr. Res , vol.108 , Issue.1-3 , pp. 85-92
    • Sun, D.1    Phillips, L.2    Velakoulis, D.3
  • 41
    • 26644458815 scopus 로고    scopus 로고
    • Volume increases in striatum associated with positive symptom reduction in schizophrenia: A preliminary observation
    • Taylor S, Christensen JD, Holcomb JM, Garver DL. Volume increases in striatum associated with positive symptom reduction in schizophrenia: a preliminary observation. Psychiatry Res. 140(1), 85-89 (2005).
    • (2005) Psychiatry Res , vol.140 , Issue.1 , pp. 85-89
    • Taylor, S.1    Christensen, J.D.2    Holcomb, J.M.3    Garver, D.L.4
  • 42
    • 67649224058 scopus 로고    scopus 로고
    • Thompson PM, Bartzokis G, Hayashi KM et al. Time-lapse mapping of cortical changes in schizophrenia with different treatments. Cereb. Cortex 19(5), 1107-1123 (2009). •• A landmark study.
    • Thompson PM, Bartzokis G, Hayashi KM et al. Time-lapse mapping of cortical changes in schizophrenia with different treatments. Cereb. Cortex 19(5), 1107-1123 (2009). •• A landmark study.
  • 43
    • 67649876638 scopus 로고    scopus 로고
    • The effects of antipsychotics on the brain: What have we learnt from structural imaging of schizophrenia? - a systematic review
    • Smieskova R, Fusar-Poli P, Allen P et al. The effects of antipsychotics on the brain: what have we learnt from structural imaging of schizophrenia? - a systematic review. Curr. Pharm. Des. 15(22), 2535-2549 (2009).
    • (2009) Curr. Pharm. Des , vol.15 , Issue.22 , pp. 2535-2549
    • Smieskova, R.1    Fusar-Poli, P.2    Allen, P.3
  • 44
    • 70449641192 scopus 로고    scopus 로고
    • Do antipsychotic drugs affect brain structure? A systematic and critical review of MRI findings
    • Important review of the effects of antipsychotic drugs on brain structure, •
    • Navari S, Dazzan P. Do antipsychotic drugs affect brain structure? A systematic and critical review of MRI findings. Psychol Med, 39(11), 1763-1777 (2009). • Important review of the effects of antipsychotic drugs on brain structure.
    • (2009) Psychol Med , vol.39 , Issue.11 , pp. 1763-1777
    • Navari, S.1    Dazzan, P.2
  • 45
    • 55949099579 scopus 로고    scopus 로고
    • Longitudinal MRI study in schizophrenia patients and their healthy siblings
    • Brans RG, van Haren NE, van Baal GC et al. Longitudinal MRI study in schizophrenia patients and their healthy siblings. Br. J. Psychiatry 193(5), 422-423 (2008).
    • (2008) Br. J. Psychiatry , vol.193 , Issue.5 , pp. 422-423
    • Brans, R.G.1    van Haren, N.E.2    van Baal, G.C.3
  • 46
    • 40049090664 scopus 로고    scopus 로고
    • Brain structure and function changes during the development of schizophrenia: The evidence from studies of subjects at increased genetic risk
    • Lawrie SM, McIntosh AM, Hall J, Owens DG, Johnstone EC. Brain structure and function changes during the development of schizophrenia: the evidence from studies of subjects at increased genetic risk. Schizophr. Bull. 34(2), 330-340 (2008).
    • (2008) Schizophr. Bull , vol.34 , Issue.2 , pp. 330-340
    • Lawrie, S.M.1    McIntosh, A.M.2    Hall, J.3    Owens, D.G.4    Johnstone, E.C.5
  • 48
    • 67349135684 scopus 로고    scopus 로고
    • The effect of ageing on grey and white matter reductions in schizophrenia
    • Bose SK, Mackinnon T, Mehta MA et al. The effect of ageing on grey and white matter reductions in schizophrenia. Schizophr. Res. 112(1-3), 7-13 (2009).
    • (2009) Schizophr. Res , vol.112 , Issue.1-3 , pp. 7-13
    • Bose, S.K.1    Mackinnon, T.2    Mehta, M.A.3
  • 49
    • 35048894824 scopus 로고    scopus 로고
    • Longitudinal grey-matter and glutamatergic losses in first-episode schizophrenia
    • Theberge J, Williamson KE, Aoyama N et al. Longitudinal grey-matter and glutamatergic losses in first-episode schizophrenia. Br. J. Psychiatry 191, 325-334 (2007).
    • (2007) Br. J. Psychiatry , vol.191 , pp. 325-334
    • Theberge, J.1    Williamson, K.E.2    Aoyama, N.3


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